eslicarbazepine acetate has been researched along with oxcarbazepine in 36 studies
| Studies (eslicarbazepine acetate) | Trials (eslicarbazepine acetate) | Recent Studies (post-2010) (eslicarbazepine acetate) | Studies (oxcarbazepine) | Trials (oxcarbazepine) | Recent Studies (post-2010) (oxcarbazepine) |
|---|---|---|---|---|---|
| 229 | 68 | 175 | 1,213 | 170 | 478 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (2.78) | 18.2507 |
| 2000's | 8 (22.22) | 29.6817 |
| 2010's | 23 (63.89) | 24.3611 |
| 2020's | 4 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| Alves, PC; Benes, J; Cunha, RA; Figueiredo, AA; Freitas, AP; Garrett, J; Learmonth, DA; Parada, A; Soares-da-Silva, P | 1 |
| Abdelrahman, A; Dosa, S; El-Tayeb, A; Hinz, S; Müller, CE; Tian, M; Weinhausen, S; Weyer, S | 1 |
| Ambrósio, AF; Araújo, I; Carvalho, AP; Carvalho, CM; Malva, JO; Silva, AP; Soares-da-Silva, P | 1 |
| Parada, A; Soares-da-Silva, P | 1 |
| Ambrósio, AF; Carvalho, AP; Carvalho, CM; Soares-Da-Silva, P | 1 |
| Almeida, L; Soares-da-Silva, P | 2 |
| Ambrósio, AF; Araújo, IM; Carvalho, AP; Carvalho, CM; Leal, EC; Malva, JO; Soares-da-Silva, P; Verdasca, MJ | 1 |
| Alves, G; Caramona, M; Castel-Branco, M; Falcão, A; Figueiredo, I; Fortuna, A; Loureiro, A | 1 |
| Alves, G; Caramona, M; Castel-Branco, M; Falcão, A; Figueiredo, I; Loureiro, A | 1 |
| Alves, G; Falcão, A; Fortuna, A; Soares-da-Silva, P; Sousa, J | 1 |
| Almeida, L; Milovan, D; Nunes, T; Rocha, JF; Romach, MK; Sellers, EM; Soares-da-Silva, P; Sokowloska, M | 1 |
| Steinhoff, BJ; Trinka, E; Wendling, AS | 1 |
| Almeida, L; Elger, C; Falcão, A; Halász, P; Perucca, E; Soares-da-Silva, P | 1 |
| Baum, L; Kwan, P; Zhang, C; Zuo, Z | 1 |
| Fernandes-Lopes, C; Loureiro, AI; Soares-da-Silva, P; Wright, LC | 1 |
| Almeida, L; Falcão, A; Nunes, T; Rocha, JF; Soares-da-Silva, P | 1 |
| Fadda, V; Giovannelli, F; Maratea, D; Verrotti, A; Zaccara, G | 1 |
| Almeida, L; Bialer, M; Elger, C; Falcão, A; Nunes, T; Soares-da-Silva, P; Vaz-da-Silva, M | 1 |
| Banach, M; Borowicz, KK; Czuczwar, SJ | 1 |
| Holtkamp, M; Peltola, J; Rocamora, R; Ryvlin, P; Sieradzan, K; Villanueva, V | 1 |
| Jiménez-Conde, J; Ley, M; Principe, A; Rocamora, R | 1 |
| Benbadis, SR; Giarratano, M; Gierbolini, J | 1 |
| Bathal, H; Ojeda, J; Parra, J; Rocamora, RA; Rodríguez-Uranga, JJ; Serrano-Castro, PJ; Villanueva, V; Viteri, C | 1 |
| Baftiu, A; Brodtkorb, E; Burns, ML; Dinarevic, J; Johannessen Landmark, C; Johannessen, SI; Kufaas, RF; Reimers, A; Svendsen, T | 1 |
| Crommen, J; Fillet, M; Janicot, B; Servais, AC; Takam, A | 1 |
| Höfler, J; Kalss, G; Kirschner, M; Kuchukhidze, G; Leitinger, M; Rohracher, A; Schmid, E; Steinhoff, BJ; Trinka, E; Wendling, AS | 1 |
| Poza-Aldea, JJ | 1 |
| Mäkinen, J; Peltola, J; Rainesalo, S | 1 |
| Cagnetti, C; Foschi, N; Lattanzi, S; Lorusso, A; Provinciali, L; Silvestrini, M | 1 |
| Andersen, NB; Nielsen, MK; Petrenaite, V | 1 |
| Intravooth, T; Juerges, K; Staack, AM; Steinhoff, BJ; Stockinger, J | 1 |
| Assenza, G; McMurray, R; Peltola, J; Rocamora, R; Villanueva, V | 1 |
| Ley, M; Principe, A; Rocamora, R | 1 |
| Bak, LK; Jakobsen, E; Krarup, S; Lindholm, SEH; Mertz, C; Pinborg, LH | 1 |
| Bialer, M; Franco, V; Odi, R; Perucca, E | 1 |
6 review(s) available for eslicarbazepine acetate and oxcarbazepine
| Article | Year |
|---|---|
Mechanisms of action of carbamazepine and its derivatives, oxcarbazepine, BIA 2-093, and BIA 2-024.
Topics: Animals; Anticonvulsants; Carbamazepine; Dibenzazepines; Epilepsy; Humans; Oxcarbazepine; Sodium Channel Blockers | 2002 |
Neurological adverse events of new generation sodium blocker antiepileptic drugs. Meta-analysis of randomized, double-blinded studies with eslicarbazepine acetate, lacosamide and oxcarbazepine.
Topics: Acetamides; Anticonvulsants; Ataxia; Carbamazepine; Dibenzazepines; Diplopia; Dizziness; Dose-Response Relationship, Drug; Double-Blind Method; Humans; Lacosamide; Nervous System Diseases; Oxcarbazepine; Randomized Controlled Trials as Topic; Risk Assessment; Sodium Channel Blockers; Treatment Outcome | 2013 |
Pharmacokinetic/pharmacodynamic evaluation of eslicarbazepine for the treatment of epilepsy.
Topics: Adult; Age Factors; Animals; Anticonvulsants; Carbamazepine; Child; Dibenzazepines; Dose-Response Relationship, Drug; Drug Therapy, Combination; Epilepsies, Partial; Humans; Oxcarbazepine | 2015 |
Carbamazepine-related antiepileptic drugs for the treatment of epilepsy - a comparative review.
Topics: Anticonvulsants; Carbamazepine; Dibenzazepines; Drugs, Generic; Epilepsy; Humans; Oxcarbazepine | 2016 |
[A proposal for a model to replace carbamazepine or oxcarbazepine by eslicarbazepine acetate in clinical practice].
Topics: Anticonvulsants; Carbamazepine; Dibenzazepines; Humans; Oxcarbazepine | 2016 |
Bioequivalence and switchability of generic antiseizure medications (ASMs): A re-appraisal based on analysis of generic ASM products approved in Europe.
Topics: Anticonvulsants; Area Under Curve; Biological Variation, Individual; Dibenzazepines; Drug Substitution; Drugs, Generic; Europe; Gabapentin; Humans; Lacosamide; Lamotrigine; Levetiracetam; Oxcarbazepine; Pregabalin; Therapeutic Equivalency; Topiramate; Vigabatrin; Zonisamide | 2021 |
6 trial(s) available for eslicarbazepine acetate and oxcarbazepine
| Article | Year |
|---|---|
Safety, tolerability and pharmacokinetic profile of BIA 2-093, a novel putative antiepileptic agent, during first administration to humans.
Topics: Administration, Oral; Adolescent; Adult; Anticonvulsants; Carbamazepine; Dibenzazepines; Dose-Response Relationship, Drug; Electroencephalography; Epilepsy; Humans; Male; Metabolic Clearance Rate; Middle Aged; Oxcarbazepine; Time Factors | 2003 |
Safety, tolerability, and pharmacokinetic profile of BIA 2-093, a novel putative antiepileptic, in a rising multiple-dose study in young healthy humans.
Topics: Adolescent; Adult; Anticonvulsants; Area Under Curve; Carbamazepine; Dibenzazepines; Dose-Response Relationship, Drug; Double-Blind Method; Half-Life; Humans; Male; Middle Aged; Oxcarbazepine; Tablets | 2004 |
Effect of eslicarbazepine acetate and oxcarbazepine on cognition and psychomotor function in healthy volunteers.
Topics: Adult; Anticonvulsants; Attention; Blood Pressure; Carbamazepine; Cognition; Dibenzazepines; Dose-Response Relationship, Drug; Drug Administration Schedule; Follow-Up Studies; Heart Rate; Humans; Learning; Middle Aged; Neuropsychological Tests; Oxcarbazepine; Psychomotor Performance; Reaction Time; Single-Blind Method; Statistics, Nonparametric; Young Adult | 2010 |
Pharmacokinetics of eslicarbazepine acetate at steady-state in adults with partial-onset seizures.
Topics: Adult; Anticonvulsants; Carbamazepine; Dibenzazepines; Dose-Response Relationship, Drug; Female; Humans; International Cooperation; Male; Middle Aged; Oxcarbazepine; Seizures; Tandem Mass Spectrometry; Time Factors; Young Adult | 2011 |
Steady-state plasma and cerebrospinal fluid pharmacokinetics and tolerability of eslicarbazepine acetate and oxcarbazepine in healthy volunteers.
Topics: Administration, Oral; Adult; Anticonvulsants; Carbamazepine; Dibenzazepines; Female; Humans; Male; Middle Aged | 2013 |
Pharmacokinetics and tolerability of eslicarbazepine acetate and oxcarbazepine at steady state in healthy volunteers.
Topics: Adult; Anticonvulsants; Area Under Curve; Carbamazepine; Chromatography, High Pressure Liquid; Cross-Over Studies; Dibenzazepines; Dose-Response Relationship, Drug; Electrocardiography; Electrochemistry; Female; Heart Rate; Humans; Male; Oxcarbazepine; Time Factors | 2013 |
24 other study(ies) available for eslicarbazepine acetate and oxcarbazepine
| Article | Year |
|---|---|
Anticonvulsant and sodium channel-blocking properties of novel 10,11-dihydro-5H-dibenz[b,f]azepine-5-carboxamide derivatives.
Topics: Amides; Animals; Anticonvulsants; Azepines; Calcium Channel Blockers; Calcium Channels; Cerebral Cortex; Electroshock; In Vitro Techniques; Ion Channel Gating; Motor Activity; Prodrugs; Rats; Seizures; Sodium; Stereoisomerism; Structure-Activity Relationship; Synaptosomes | 1999 |
Carbamazepine derivatives with P2X4 receptor-blocking activity.
Topics: Adenosine Triphosphate; Animals; Calcium; Carbamazepine; Chemistry Techniques, Synthetic; Dibenzazepines; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Humans; Inhibitory Concentration 50; Mice; Purinergic P2X Receptor Antagonists; Rats; Receptors, Purinergic P2X4; Structure-Activity Relationship | 2014 |
Neurotoxic/neuroprotective profile of carbamazepine, oxcarbazepine and two new putative antiepileptic drugs, BIA 2-093 and BIA 2-024.
Topics: Animals; Anticonvulsants; Carbamazepine; Caspase 3; Caspases; Cells, Cultured; Dibenzazepines; Excitatory Amino Acid Antagonists; Female; Hippocampus; Neuroprotective Agents; Oxcarbazepine; Pregnancy; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 2000 |
The novel anticonvulsant BIA 2-093 inhibits transmitter release during opening of voltage-gated sodium channels: a comparison with carbamazepine and oxcarbazepine.
Topics: Animals; Anticonvulsants; Carbamazepine; Corpus Striatum; Dibenzazepines; Electrophysiology; In Vitro Techniques; Ion Channel Gating; Male; Neurotransmitter Agents; Oxcarbazepine; Rats; Rats, Wistar; Sodium Channels; Veratrine | 2002 |
Neurotoxicity induced by antiepileptic drugs in cultured hippocampal neurons: a comparative study between carbamazepine, oxcarbazepine, and two new putative antiepileptic drugs, BIA 2-024 and BIA 2-093.
Topics: Animals; Anticonvulsants; Carbamazepine; Cell Survival; Cells, Cultured; Dibenzazepines; Epilepsy; Hippocampus; Immunohistochemistry; Neurons; Neurotoxicity Syndromes; Rats; Rats, Wistar; Reactive Oxygen Species; Toxicity Tests | 2004 |
Enantioselective HPLC-UV method for determination of eslicarbazepine acetate (BIA 2-093) and its metabolites in human plasma.
Topics: Calibration; Carbamazepine; Chromatography, High Pressure Liquid; Dibenzazepines; Drug Monitoring; Drug Stability; Humans; Molecular Structure; Oxcarbazepine; Plasma; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Spectrophotometry, Ultraviolet; Stereoisomerism | 2007 |
Simultaneous and enantioselective liquid chromatographic determination of eslicarbazepine acetate, S-licarbazepine, R-licarbazepine and oxcarbazepine in mouse tissue samples using ultraviolet detection.
Topics: Animals; Calibration; Carbamazepine; Chromatography, Liquid; Dibenzazepines; Mice; Mice, Inbred Strains; Oxcarbazepine; Sensitivity and Specificity; Spectrophotometry, Ultraviolet; Stereoisomerism; Tissue Distribution | 2007 |
Development and validation of an HPLC-UV method for the simultaneous quantification of carbamazepine, oxcarbazepine, eslicarbazepine acetate and their main metabolites in human plasma.
Topics: Carbamazepine; Chromatography, High Pressure Liquid; Dibenzazepines; Humans; Molecular Structure; Oxcarbazepine; Sensitivity and Specificity; Spectrophotometry, Ultraviolet; Stereoisomerism | 2010 |
[Abrupt switch from extended-release oxcarbazepine to eslicarbazepine acetate].
Topics: Adult; Anticonvulsants; Carbamazepine; Delayed-Action Preparations; Dibenzazepines; Drug Therapy, Combination; Epilepsy; Female; Humans; Male; Middle Aged; Oxcarbazepine; Treatment Outcome; Young Adult | 2011 |
In vitro transport profile of carbamazepine, oxcarbazepine, eslicarbazepine acetate, and their active metabolites by human P-glycoprotein.
Topics: Animals; Anticonvulsants; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Carbamazepine; Cell Line; Dibenzazepines; Drug Resistance; Flow Cytometry; Fluorescent Antibody Technique; Humans; In Vitro Techniques; LLC-PK1 Cells; Oxcarbazepine; Polymerase Chain Reaction; Swine | 2011 |
Development and validation of an enantioselective liquid-chromatography/tandem mass spectrometry method for the separation and quantification of eslicarbazepine acetate, eslicarbazepine, R-licarbazepine and oxcarbazepine in human plasma.
Topics: Carbamazepine; Chromatography, Liquid; Dibenzazepines; Drug Stability; Humans; Male; Oxcarbazepine; Reproducibility of Results; Sensitivity and Specificity; Solid Phase Extraction; Stereoisomerism; Tandem Mass Spectrometry | 2011 |
Practical guidance and considerations for transitioning patients from oxcarbazepine or carbamazepine to eslicarbazepine acetate--Expert opinion.
Topics: Anticonvulsants; Attitude of Health Personnel; Carbamazepine; Dibenzazepines; Drug Substitution; Drug Therapy, Combination; Epilepsy; Humans; Oxcarbazepine; Voltage-Gated Sodium Channel Blockers | 2015 |
Assessing long-term effects of eslicarbazepine acetate on lipid metabolism profile, sodium values and liver function tests.
Topics: Adult; Anticonvulsants; Carbamazepine; Cholesterol; Dibenzazepines; Dyslipidemias; Epilepsy; Female; Humans; Liver Function Tests; Male; Outpatients; Oxcarbazepine; Retrospective Studies; Sodium; Time Factors; Triglycerides | 2015 |
EPICON consensus: recommendations for proper management of switching to eslicarbazepine acetate in epilepsy.
Topics: Anticonvulsants; Carbamazepine; Consensus; Delphi Technique; Dibenzazepines; Drug Substitution; Epilepsy; Guidelines as Topic; Humans; Neurologists; Oxcarbazepine; Surveys and Questionnaires; Voltage-Gated Sodium Channel Blockers | 2018 |
The Impact of Pharmacokinetic Interactions With Eslicarbazepine Acetate Versus Oxcarbazepine and Carbamazepine in Clinical Practice.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Dibenzazepines; Drug Interactions; Drug Monitoring; Female; Humans; Infant; Infant, Newborn; Lamotrigine; Male; Middle Aged; Norway; Oxcarbazepine; Triazines; Valproic Acid; Young Adult | 2016 |
Liquid chromatography separation of the chiral prodrug eslicarbazepine acetate and its main metabolites in polar organic mode. Application to their analysis after in vitro metabolism.
Topics: Acetic Acid; Acetonitriles; Carbamazepine; Cellulose; Chromatography, Liquid; Dibenzazepines; Diethylamines; Humans; Microsomes, Liver; Oxcarbazepine; Phenylcarbamates; Prodrugs; Solid Phase Extraction; Solvents; Stereoisomerism | 2016 |
Overnight switching from oxcarbazepine to eslicarbazepine acetate: an observational study.
Topics: Adult; Aged; Anticonvulsants; Carbamazepine; Dibenzazepines; Drug Resistant Epilepsy; Drug Substitution; Female; Humans; Male; Middle Aged; Oxcarbazepine | 2017 |
Transition from oxcarbazepine to eslicarbazepine acetate: A single center study.
Topics: Adult; Aged; Carbamazepine; Dibenzazepines; Drug Substitution; Epilepsy; Female; Follow-Up Studies; Humans; Male; Middle Aged; Outcome Assessment, Health Care; Oxcarbazepine; Registries; Voltage-Gated Sodium Channel Blockers; Young Adult | 2017 |
Eslicarbazepine acetate as adjunctive treatment in partial-onset epilepsy.
Topics: Adult; Anticonvulsants; Carbamazepine; Dibenzazepines; Drug Therapy, Combination; Epilepsies, Partial; Female; Humans; Male; Middle Aged; Oxcarbazepine; Retrospective Studies; Seizures; Young Adult | 2018 |
Clinical experience with eslicarbazepine acetate in adults with sub-analysis of elderly.
Topics: Adult; Age Factors; Aged; Anticonvulsants; Carbamazepine; Dibenzazepines; Drug Therapy, Combination; Epilepsies, Partial; Female; Humans; Male; Middle Aged; Outcome Assessment, Health Care; Retrospective Studies; Voltage-Gated Sodium Channel Blockers; Young Adult | 2017 |
Antiepileptic drugs-induced hyponatremia: Review and analysis of 560 hospitalized patients.
Topics: Adult; Aged; Anticonvulsants; Carbamazepine; Dibenzazepines; Epilepsy; Female; Hospitalization; Humans; Hyponatremia; Incidence; Male; Oxcarbazepine; Young Adult | 2018 |
Safety, tolerability and effectiveness of transition to eslicarbazepine acetate from carbamazepine or oxcarbazepine in clinical practice.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticonvulsants; Carbamazepine; Clinical Studies as Topic; Dibenzazepines; Drug Substitution; Drug-Related Side Effects and Adverse Reactions; Europe; Female; Follow-Up Studies; Humans; Male; Middle Aged; Outcome Assessment, Health Care; Oxcarbazepine; Young Adult | 2020 |
[Long-term effects of dibenzazepines on metabolic parameters: retrospective comparison of carbamazepine, oxcarbazepine and eslicarbazepine acetate in the real world].
Topics: Adult; Aged; Alanine Transaminase; Anticonvulsants; Aspartate Aminotransferases; Carbamazepine; Dibenzazepines; Epilepsies, Partial; Female; Follow-Up Studies; gamma-Glutamyltransferase; Healthy Lifestyle; Humans; Hyponatremia; Leukocyte Count; Lipids; Male; Metabolism; Middle Aged; Nerve Tissue Proteins; Oxcarbazepine; Retrospective Studies; Sodium; Voltage-Gated Sodium Channels | 2020 |
Distinct effects on cAMP signaling of carbamazepine and its structural derivatives do not correlate with their clinical efficacy in epilepsy.
Topics: Adenylyl Cyclases; Anticonvulsants; Calcium Signaling; Carbamazepine; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Dibenzazepines; Epilepsy; HEK293 Cells; Humans; Oxcarbazepine; Seizures; Signal Transduction; Treatment Outcome | 2020 |