Page last updated: 2024-09-05

eslicarbazepine acetate and carbamazepine

eslicarbazepine acetate has been researched along with carbamazepine in 48 studies

Compound Research Comparison

Studies
(eslicarbazepine acetate)
Trials
(eslicarbazepine acetate)
Recent Studies (post-2010)
(eslicarbazepine acetate)
Studies
(carbamazepine)
Trials
(carbamazepine)
Recent Studies (post-2010) (carbamazepine)
2296817511,9921,1283,101

Research

Studies (48)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (2.08)18.2507
2000's11 (22.92)29.6817
2010's32 (66.67)24.3611
2020's4 (8.33)2.80

Authors

AuthorsStudies
Alves, PC; Benes, J; Cunha, RA; Figueiredo, AA; Freitas, AP; Garrett, J; Learmonth, DA; Parada, A; Soares-da-Silva, P1
Abdelrahman, A; Dosa, S; El-Tayeb, A; Hinz, S; Müller, CE; Tian, M; Weinhausen, S; Weyer, S1
Ambrósio, AF; Araújo, I; Carvalho, AP; Carvalho, CM; Malva, JO; Silva, AP; Soares-da-Silva, P1
Hainzl, D; Parada, A; Soares-da-Silva, P1
Bonifácio, MJ; Cunha, RA; Parada, A; Patmore, L; Sheridan, RD; Soares-da-Silva, P1
Parada, A; Soares-da-Silva, P1
Ambrósio, AF; Carvalho, AP; Carvalho, CM; Soares-Da-Silva, P1
Coelho, JE; Costenla, AR; Cunha, RA; de Mendonça, A; Lopes, LV; Parada, A; Ribeiro, JA; Sebastião, AM1
Almeida, L; Soares-da-Silva, P2
Ambrósio, AF; Araújo, IM; Carvalho, AP; Carvalho, CM; Leal, EC; Malva, JO; Soares-da-Silva, P; Verdasca, MJ1
Alves, G; Caramona, M; Castel-Branco, M; Falcão, A; Figueiredo, I; Fortuna, A; Loureiro, A1
Alves, G; Caramona, M; Castel-Branco, M; Falcão, A; Figueiredo, I; Loureiro, A1
Alves, G; Falcão, A; Fortuna, A; Soares-da-Silva, P; Sousa, J1
Almeida, A; Alves, G; Direito, R; Falcão, A; Fortuna, A; Rocha, M; Soares-da-Silva, P; Sousa, J1
Almeida, L; Milovan, D; Nunes, T; Rocha, JF; Romach, MK; Sellers, EM; Soares-da-Silva, P; Sokowloska, M1
Steinhoff, BJ; Trinka, E; Wendling, AS1
Alves, G; Bicker, J; Falcão, A; Fortuna, A; Soares-da-Silva, P1
Almeida, L; Elger, C; Falcão, A; Halász, P; Perucca, E; Soares-da-Silva, P1
Baum, L; Kwan, P; Zhang, C; Zuo, Z1
Fernandes-Lopes, C; Loureiro, AI; Soares-da-Silva, P; Wright, LC1
Almeida, L; Falcão, A; Nunes, T; Rocha, JF; Soares-da-Silva, P1
Fadda, V; Giovannelli, F; Maratea, D; Verrotti, A; Zaccara, G1
Almeida, L; Bialer, M; Elger, C; Falcão, A; Nunes, T; Soares-da-Silva, P; Vaz-da-Silva, M1
Banach, M; Borowicz, KK; Czuczwar, SJ1
Holtkamp, M; Peltola, J; Rocamora, R; Ryvlin, P; Sieradzan, K; Villanueva, V1
Jiménez-Conde, J; Ley, M; Principe, A; Rocamora, R1
Benbadis, SR; Giarratano, M; Gierbolini, J1
Bathal, H; Ojeda, J; Parra, J; Rocamora, RA; Rodríguez-Uranga, JJ; Serrano-Castro, PJ; Villanueva, V; Viteri, C1
Baftiu, A; Brodtkorb, E; Burns, ML; Dinarevic, J; Johannessen Landmark, C; Johannessen, SI; Kufaas, RF; Reimers, A; Svendsen, T1
Crommen, J; Fillet, M; Janicot, B; Servais, AC; Takam, A1
Höfler, J; Kalss, G; Kirschner, M; Kuchukhidze, G; Leitinger, M; Rohracher, A; Schmid, E; Steinhoff, BJ; Trinka, E; Wendling, AS1
Poza-Aldea, JJ1
Mäkinen, J; Peltola, J; Rainesalo, S1
Kay, L; Klein, KM; Reif, PS; Rosenow, F; Strzelczyk, A; Willems, LM; Zöllner, JP1
Cagnetti, C; Foschi, N; Lattanzi, S; Lorusso, A; Provinciali, L; Silvestrini, M1
Andersen, NB; Nielsen, MK; Petrenaite, V1
Ben-Menachem, E; Elger, C; Keller, B; Kowacs, PA; Löffler, K; Rocha, JF; Soares-da-Silva, P; Trinka, E1
Blum, D; Cheng, H; Grinnell, T; Harvey, JH; Pazdera, L; Sam, MC; Sperling, MR; Strom, LA1
Rocha, JF; Soares-da-Silva, P; Trinka, E1
Brigo, F; Lattanzi, S1
Intravooth, T; Juerges, K; Staack, AM; Steinhoff, BJ; Stockinger, J1
Abou-Khalil, B; Blum, D; Cheng, H; Gama, H; Grinnell, T; Jung, J; Klein, P; Rocha, F; Ryvlin, P; Shah, A; Specchio, LM1
Boyd, A; Falco-Walter, J; Le, S; Loring, DW; Meador, KJ; Razavi, B; Seliger, J1
Assenza, G; McMurray, R; Peltola, J; Rocamora, R; Villanueva, V1
Lawthom, C; Maguire, M; O'Dwyer, M; Oak, K; Shankar, R; Thomas, R; Watkins, L1
Ley, M; Principe, A; Rocamora, R1
Bak, LK; Jakobsen, E; Krarup, S; Lindholm, SEH; Mertz, C; Pinborg, LH1

Reviews

6 review(s) available for eslicarbazepine acetate and carbamazepine

ArticleYear
Mechanisms of action of carbamazepine and its derivatives, oxcarbazepine, BIA 2-093, and BIA 2-024.
    Neurochemical research, 2002, Volume: 27, Issue:1-2

    Topics: Animals; Anticonvulsants; Carbamazepine; Dibenzazepines; Epilepsy; Humans; Oxcarbazepine; Sodium Channel Blockers

2002
Neurological adverse events of new generation sodium blocker antiepileptic drugs. Meta-analysis of randomized, double-blinded studies with eslicarbazepine acetate, lacosamide and oxcarbazepine.
    Seizure, 2013, Volume: 22, Issue:7

    Topics: Acetamides; Anticonvulsants; Ataxia; Carbamazepine; Dibenzazepines; Diplopia; Dizziness; Dose-Response Relationship, Drug; Double-Blind Method; Humans; Lacosamide; Nervous System Diseases; Oxcarbazepine; Randomized Controlled Trials as Topic; Risk Assessment; Sodium Channel Blockers; Treatment Outcome

2013
Pharmacokinetic/pharmacodynamic evaluation of eslicarbazepine for the treatment of epilepsy.
    Expert opinion on drug metabolism & toxicology, 2015, Volume: 11, Issue:4

    Topics: Adult; Age Factors; Animals; Anticonvulsants; Carbamazepine; Child; Dibenzazepines; Dose-Response Relationship, Drug; Drug Therapy, Combination; Epilepsies, Partial; Humans; Oxcarbazepine

2015
Carbamazepine-related antiepileptic drugs for the treatment of epilepsy - a comparative review.
    Expert opinion on pharmacotherapy, 2016, Volume: 17, Issue:7

    Topics: Anticonvulsants; Carbamazepine; Dibenzazepines; Drugs, Generic; Epilepsy; Humans; Oxcarbazepine

2016
[A proposal for a model to replace carbamazepine or oxcarbazepine by eslicarbazepine acetate in clinical practice].
    Revista de neurologia, 2016, Sep-01, Volume: 63, Issue:5

    Topics: Anticonvulsants; Carbamazepine; Dibenzazepines; Humans; Oxcarbazepine

2016
The evidence for switching dibenzazepines in people with epilepsy.
    Acta neurologica Scandinavica, 2020, Volume: 142, Issue:2

    Topics: Anticonvulsants; Carbamazepine; Dibenzazepines; Drug Substitution; Epilepsy; Evidence-Based Medicine; Humans

2020

Trials

10 trial(s) available for eslicarbazepine acetate and carbamazepine

ArticleYear
Safety, tolerability and pharmacokinetic profile of BIA 2-093, a novel putative antiepileptic agent, during first administration to humans.
    Drugs in R&D, 2003, Volume: 4, Issue:5

    Topics: Administration, Oral; Adolescent; Adult; Anticonvulsants; Carbamazepine; Dibenzazepines; Dose-Response Relationship, Drug; Electroencephalography; Epilepsy; Humans; Male; Metabolic Clearance Rate; Middle Aged; Oxcarbazepine; Time Factors

2003
Safety, tolerability, and pharmacokinetic profile of BIA 2-093, a novel putative antiepileptic, in a rising multiple-dose study in young healthy humans.
    Journal of clinical pharmacology, 2004, Volume: 44, Issue:8

    Topics: Adolescent; Adult; Anticonvulsants; Area Under Curve; Carbamazepine; Dibenzazepines; Dose-Response Relationship, Drug; Double-Blind Method; Half-Life; Humans; Male; Middle Aged; Oxcarbazepine; Tablets

2004
Effect of eslicarbazepine acetate and oxcarbazepine on cognition and psychomotor function in healthy volunteers.
    Epilepsy & behavior : E&B, 2010, Volume: 18, Issue:4

    Topics: Adult; Anticonvulsants; Attention; Blood Pressure; Carbamazepine; Cognition; Dibenzazepines; Dose-Response Relationship, Drug; Drug Administration Schedule; Follow-Up Studies; Heart Rate; Humans; Learning; Middle Aged; Neuropsychological Tests; Oxcarbazepine; Psychomotor Performance; Reaction Time; Single-Blind Method; Statistics, Nonparametric; Young Adult

2010
Pharmacokinetics of eslicarbazepine acetate at steady-state in adults with partial-onset seizures.
    Epilepsy research, 2011, Volume: 96, Issue:1-2

    Topics: Adult; Anticonvulsants; Carbamazepine; Dibenzazepines; Dose-Response Relationship, Drug; Female; Humans; International Cooperation; Male; Middle Aged; Oxcarbazepine; Seizures; Tandem Mass Spectrometry; Time Factors; Young Adult

2011
Steady-state plasma and cerebrospinal fluid pharmacokinetics and tolerability of eslicarbazepine acetate and oxcarbazepine in healthy volunteers.
    Epilepsia, 2013, Volume: 54, Issue:1

    Topics: Administration, Oral; Adult; Anticonvulsants; Carbamazepine; Dibenzazepines; Female; Humans; Male; Middle Aged

2013
Pharmacokinetics and tolerability of eslicarbazepine acetate and oxcarbazepine at steady state in healthy volunteers.
    Epilepsia, 2013, Volume: 54, Issue:8

    Topics: Adult; Anticonvulsants; Area Under Curve; Carbamazepine; Chromatography, High Pressure Liquid; Cross-Over Studies; Dibenzazepines; Dose-Response Relationship, Drug; Electrocardiography; Electrochemistry; Female; Heart Rate; Humans; Male; Oxcarbazepine; Time Factors

2013
Efficacy and safety of eslicarbazepine acetate versus controlled-release carbamazepine monotherapy in newly diagnosed epilepsy: A phase III double-blind, randomized, parallel-group, multicenter study.
    Epilepsia, 2018, Volume: 59, Issue:2

    Topics: Adult; Alanine Transaminase; Anticonvulsants; Carbamazepine; Delayed-Action Preparations; Dibenzazepines; Dizziness; Dose-Response Relationship, Drug; Double-Blind Method; Epilepsies, Partial; Equivalence Trials as Topic; Fatigue; Female; gamma-Glutamyltransferase; Headache; Humans; Logistic Models; Male; Middle Aged; Nausea; Treatment Outcome; Voltage-Gated Sodium Channel Blockers; Young Adult

2018
Efficacy and safety of eslicarbazepine acetate monotherapy in patients converting from carbamazepine.
    Epilepsia, 2018, Volume: 59, Issue:3

    Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Dibenzazepines; Drug Resistant Epilepsy; Drug Substitution; Female; Humans; Male; Middle Aged; Nausea; Treatment Outcome; Voltage-Gated Sodium Channel Blockers; Young Adult

2018
Tolerability of adjunctive eslicarbazepine acetate according to concomitant lamotrigine or carbamazepine use: A subgroup analysis of three phase III trials in adults with focal (partial-onset) seizures.
    Epilepsy research, 2018, Volume: 147

    Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Dibenzazepines; Diplopia; Dose-Response Relationship, Drug; Double-Blind Method; Female; Follow-Up Studies; Humans; Lamotrigine; Male; Randomized Controlled Trials as Topic; Seizures; Vomiting; Young Adult

2018
Comparative neuropsychological effects of carbamazepine and eslicarbazepine acetate.
    Epilepsy & behavior : E&B, 2019, Volume: 94

    Topics: Adolescent; Adult; Affect; Anticonvulsants; Attention; Carbamazepine; Cross-Over Studies; Dibenzazepines; Double-Blind Method; Epilepsy; Female; Healthy Volunteers; Humans; Male; Memory; Middle Aged; Neuropsychological Tests; Psychomotor Performance; Spatial Memory; Stroop Test; Treatment Outcome; Young Adult

2019

Other Studies

32 other study(ies) available for eslicarbazepine acetate and carbamazepine

ArticleYear
Anticonvulsant and sodium channel-blocking properties of novel 10,11-dihydro-5H-dibenz[b,f]azepine-5-carboxamide derivatives.
    Journal of medicinal chemistry, 1999, Jul-15, Volume: 42, Issue:14

    Topics: Amides; Animals; Anticonvulsants; Azepines; Calcium Channel Blockers; Calcium Channels; Cerebral Cortex; Electroshock; In Vitro Techniques; Ion Channel Gating; Motor Activity; Prodrugs; Rats; Seizures; Sodium; Stereoisomerism; Structure-Activity Relationship; Synaptosomes

1999
Carbamazepine derivatives with P2X4 receptor-blocking activity.
    Bioorganic & medicinal chemistry, 2014, Feb-01, Volume: 22, Issue:3

    Topics: Adenosine Triphosphate; Animals; Calcium; Carbamazepine; Chemistry Techniques, Synthetic; Dibenzazepines; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Humans; Inhibitory Concentration 50; Mice; Purinergic P2X Receptor Antagonists; Rats; Receptors, Purinergic P2X4; Structure-Activity Relationship

2014
Neurotoxic/neuroprotective profile of carbamazepine, oxcarbazepine and two new putative antiepileptic drugs, BIA 2-093 and BIA 2-024.
    European journal of pharmacology, 2000, Oct-13, Volume: 406, Issue:2

    Topics: Animals; Anticonvulsants; Carbamazepine; Caspase 3; Caspases; Cells, Cultured; Dibenzazepines; Excitatory Amino Acid Antagonists; Female; Hippocampus; Neuroprotective Agents; Oxcarbazepine; Pregnancy; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate

2000
Metabolism of two new antiepileptic drugs and their principal metabolites S(+)- and R(-)-10,11-dihydro-10-hydroxy carbamazepine.
    Epilepsy research, 2001, Volume: 44, Issue:2-3

    Topics: Animals; Anticonvulsants; Brain; Carbamazepine; Dibenzazepines; Humans; Liver; Male; Mice; Rabbits; Rats; Rats, Wistar; Stereoisomerism

2001
Interaction of the novel anticonvulsant, BIA 2-093, with voltage-gated sodium channels: comparison with carbamazepine.
    Epilepsia, 2001, Volume: 42, Issue:5

    Topics: Animals; Anticonvulsants; Batrachotoxins; Brain; Carbamazepine; Cerebral Cortex; Dibenzazepines; Mice; Patch-Clamp Techniques; Saxitoxin; Sodium; Sodium Channels; Synaptosomes; Tumor Cells, Cultured; Veratridine

2001
The novel anticonvulsant BIA 2-093 inhibits transmitter release during opening of voltage-gated sodium channels: a comparison with carbamazepine and oxcarbazepine.
    Neurochemistry international, 2002, Volume: 40, Issue:5

    Topics: Animals; Anticonvulsants; Carbamazepine; Corpus Striatum; Dibenzazepines; Electrophysiology; In Vitro Techniques; Ion Channel Gating; Male; Neurotransmitter Agents; Oxcarbazepine; Rats; Rats, Wistar; Sodium Channels; Veratrine

2002
Effects of carbamazepine and novel 10,11-dihydro-5H-dibenz[b,f]azepine-5-carboxamide derivatives on synaptic transmission in rat hippocampal slices.
    Pharmacology & toxicology, 2002, Volume: 90, Issue:4

    Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Anticonvulsants; Carbamazepine; Dibenzazepines; Dose-Response Relationship, Drug; Excitatory Postsynaptic Potentials; Hippocampus; In Vitro Techniques; Picrotoxin; Rats; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission

2002
Neurotoxicity induced by antiepileptic drugs in cultured hippocampal neurons: a comparative study between carbamazepine, oxcarbazepine, and two new putative antiepileptic drugs, BIA 2-024 and BIA 2-093.
    Epilepsia, 2004, Volume: 45, Issue:12

    Topics: Animals; Anticonvulsants; Carbamazepine; Cell Survival; Cells, Cultured; Dibenzazepines; Epilepsy; Hippocampus; Immunohistochemistry; Neurons; Neurotoxicity Syndromes; Rats; Rats, Wistar; Reactive Oxygen Species; Toxicity Tests

2004
Enantioselective HPLC-UV method for determination of eslicarbazepine acetate (BIA 2-093) and its metabolites in human plasma.
    Biomedical chromatography : BMC, 2007, Volume: 21, Issue:11

    Topics: Calibration; Carbamazepine; Chromatography, High Pressure Liquid; Dibenzazepines; Drug Monitoring; Drug Stability; Humans; Molecular Structure; Oxcarbazepine; Plasma; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Spectrophotometry, Ultraviolet; Stereoisomerism

2007
Simultaneous and enantioselective liquid chromatographic determination of eslicarbazepine acetate, S-licarbazepine, R-licarbazepine and oxcarbazepine in mouse tissue samples using ultraviolet detection.
    Analytica chimica acta, 2007, Jul-16, Volume: 596, Issue:1

    Topics: Animals; Calibration; Carbamazepine; Chromatography, Liquid; Dibenzazepines; Mice; Mice, Inbred Strains; Oxcarbazepine; Sensitivity and Specificity; Spectrophotometry, Ultraviolet; Stereoisomerism; Tissue Distribution

2007
Development and validation of an HPLC-UV method for the simultaneous quantification of carbamazepine, oxcarbazepine, eslicarbazepine acetate and their main metabolites in human plasma.
    Analytical and bioanalytical chemistry, 2010, Volume: 397, Issue:4

    Topics: Carbamazepine; Chromatography, High Pressure Liquid; Dibenzazepines; Humans; Molecular Structure; Oxcarbazepine; Sensitivity and Specificity; Spectrophotometry, Ultraviolet; Stereoisomerism

2010
Enantioselective assay for therapeutic drug monitoring of eslicarbazepine acetate: no interference with carbamazepine and its metabolites.
    Therapeutic drug monitoring, 2010, Volume: 32, Issue:4

    Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Dibenzazepines; Drug Monitoring; Female; Humans; Indicators and Reagents; Male; Middle Aged; Spectrophotometry, Ultraviolet; Stereoisomerism; Young Adult

2010
[Abrupt switch from extended-release oxcarbazepine to eslicarbazepine acetate].
    Der Nervenarzt, 2011, Volume: 82, Issue:6

    Topics: Adult; Anticonvulsants; Carbamazepine; Delayed-Action Preparations; Dibenzazepines; Drug Therapy, Combination; Epilepsy; Female; Humans; Male; Middle Aged; Oxcarbazepine; Treatment Outcome; Young Adult

2011
A chiral HPLC-UV method for the quantification of dibenz[b,f]azepine-5-carboxamide derivatives in mouse plasma and brain tissue: eslicarbazepine acetate, carbamazepine and main metabolites.
    Journal of separation science, 2011, Volume: 34, Issue:12

    Topics: Animals; Anticonvulsants; Brain; Brain Chemistry; Carbamazepine; Chromatography, High Pressure Liquid; Dibenzazepines; Epilepsy; Humans; Male; Mice; Models, Animal

2011
In vitro transport profile of carbamazepine, oxcarbazepine, eslicarbazepine acetate, and their active metabolites by human P-glycoprotein.
    Epilepsia, 2011, Volume: 52, Issue:10

    Topics: Animals; Anticonvulsants; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Carbamazepine; Cell Line; Dibenzazepines; Drug Resistance; Flow Cytometry; Fluorescent Antibody Technique; Humans; In Vitro Techniques; LLC-PK1 Cells; Oxcarbazepine; Polymerase Chain Reaction; Swine

2011
Development and validation of an enantioselective liquid-chromatography/tandem mass spectrometry method for the separation and quantification of eslicarbazepine acetate, eslicarbazepine, R-licarbazepine and oxcarbazepine in human plasma.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2011, Sep-01, Volume: 879, Issue:25

    Topics: Carbamazepine; Chromatography, Liquid; Dibenzazepines; Drug Stability; Humans; Male; Oxcarbazepine; Reproducibility of Results; Sensitivity and Specificity; Solid Phase Extraction; Stereoisomerism; Tandem Mass Spectrometry

2011
Practical guidance and considerations for transitioning patients from oxcarbazepine or carbamazepine to eslicarbazepine acetate--Expert opinion.
    Epilepsy & behavior : E&B, 2015, Volume: 50

    Topics: Anticonvulsants; Attitude of Health Personnel; Carbamazepine; Dibenzazepines; Drug Substitution; Drug Therapy, Combination; Epilepsy; Humans; Oxcarbazepine; Voltage-Gated Sodium Channel Blockers

2015
Assessing long-term effects of eslicarbazepine acetate on lipid metabolism profile, sodium values and liver function tests.
    Epilepsy research, 2015, Volume: 115

    Topics: Adult; Anticonvulsants; Carbamazepine; Cholesterol; Dibenzazepines; Dyslipidemias; Epilepsy; Female; Humans; Liver Function Tests; Male; Outpatients; Oxcarbazepine; Retrospective Studies; Sodium; Time Factors; Triglycerides

2015
EPICON consensus: recommendations for proper management of switching to eslicarbazepine acetate in epilepsy.
    Neurologia, 2018, Volume: 33, Issue:5

    Topics: Anticonvulsants; Carbamazepine; Consensus; Delphi Technique; Dibenzazepines; Drug Substitution; Epilepsy; Guidelines as Topic; Humans; Neurologists; Oxcarbazepine; Surveys and Questionnaires; Voltage-Gated Sodium Channel Blockers

2018
The Impact of Pharmacokinetic Interactions With Eslicarbazepine Acetate Versus Oxcarbazepine and Carbamazepine in Clinical Practice.
    Therapeutic drug monitoring, 2016, Volume: 38, Issue:4

    Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Dibenzazepines; Drug Interactions; Drug Monitoring; Female; Humans; Infant; Infant, Newborn; Lamotrigine; Male; Middle Aged; Norway; Oxcarbazepine; Triazines; Valproic Acid; Young Adult

2016
Liquid chromatography separation of the chiral prodrug eslicarbazepine acetate and its main metabolites in polar organic mode. Application to their analysis after in vitro metabolism.
    Journal of chromatography. A, 2016, Oct-07, Volume: 1467

    Topics: Acetic Acid; Acetonitriles; Carbamazepine; Cellulose; Chromatography, Liquid; Dibenzazepines; Diethylamines; Humans; Microsomes, Liver; Oxcarbazepine; Phenylcarbamates; Prodrugs; Solid Phase Extraction; Solvents; Stereoisomerism

2016
Overnight switching from oxcarbazepine to eslicarbazepine acetate: an observational study.
    Acta neurologica Scandinavica, 2017, Volume: 135, Issue:4

    Topics: Adult; Aged; Anticonvulsants; Carbamazepine; Dibenzazepines; Drug Resistant Epilepsy; Drug Substitution; Female; Humans; Male; Middle Aged; Oxcarbazepine

2017
Transition from oxcarbazepine to eslicarbazepine acetate: A single center study.
    Brain and behavior, 2017, Volume: 7, Issue:3

    Topics: Adult; Aged; Carbamazepine; Dibenzazepines; Drug Substitution; Epilepsy; Female; Follow-Up Studies; Humans; Male; Middle Aged; Outcome Assessment, Health Care; Oxcarbazepine; Registries; Voltage-Gated Sodium Channel Blockers; Young Adult

2017
Eslicarbazepine acetate as a therapeutic option in a patient with carbamazepine-induced rash and HLA-A*31:01.
    Seizure, 2017, Volume: 47

    Topics: Adult; Anticonvulsants; Carbamazepine; Dibenzazepines; Epilepsy, Frontal Lobe; Exanthema; Female; Haplotypes; HLA-B15 Antigen; Humans; Pharmacogenomic Variants; Voltage-Gated Sodium Channel Blockers

2017
Eslicarbazepine acetate as adjunctive treatment in partial-onset epilepsy.
    Acta neurologica Scandinavica, 2018, Volume: 137, Issue:1

    Topics: Adult; Anticonvulsants; Carbamazepine; Dibenzazepines; Drug Therapy, Combination; Epilepsies, Partial; Female; Humans; Male; Middle Aged; Oxcarbazepine; Retrospective Studies; Seizures; Young Adult

2018
Clinical experience with eslicarbazepine acetate in adults with sub-analysis of elderly.
    Seizure, 2017, Volume: 53

    Topics: Adult; Age Factors; Aged; Anticonvulsants; Carbamazepine; Dibenzazepines; Drug Therapy, Combination; Epilepsies, Partial; Female; Humans; Male; Middle Aged; Outcome Assessment, Health Care; Retrospective Studies; Voltage-Gated Sodium Channel Blockers; Young Adult

2017
Response: Comparing the dosages of lacosamide, eslicarbazepine acetate, and controlled-release carbamazepine in noninferiority epilepsy monotherapy trials: How much "fair" is "fair".
    Epilepsia, 2018, Volume: 59, Issue:4

    Topics: Acetamides; Anticonvulsants; Carbamazepine; Delayed-Action Preparations; Dibenzazepines; Epilepsy; Humans; Lacosamide

2018
Comparing the dosages of lacosamide, eslicarbazepine acetate, and controlled-release carbamazepine in noninferiority epilepsy monotherapy trials: How much "fair" is "fair"?
    Epilepsia, 2018, Volume: 59, Issue:4

    Topics: Acetamides; Anticonvulsants; Carbamazepine; Delayed-Action Preparations; Dibenzazepines; Epilepsy; Humans; Lacosamide

2018
Antiepileptic drugs-induced hyponatremia: Review and analysis of 560 hospitalized patients.
    Epilepsy research, 2018, Volume: 143

    Topics: Adult; Aged; Anticonvulsants; Carbamazepine; Dibenzazepines; Epilepsy; Female; Hospitalization; Humans; Hyponatremia; Incidence; Male; Oxcarbazepine; Young Adult

2018
Safety, tolerability and effectiveness of transition to eslicarbazepine acetate from carbamazepine or oxcarbazepine in clinical practice.
    Seizure, 2020, Volume: 75

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticonvulsants; Carbamazepine; Clinical Studies as Topic; Dibenzazepines; Drug Substitution; Drug-Related Side Effects and Adverse Reactions; Europe; Female; Follow-Up Studies; Humans; Male; Middle Aged; Outcome Assessment, Health Care; Oxcarbazepine; Young Adult

2020
[Long-term effects of dibenzazepines on metabolic parameters: retrospective comparison of carbamazepine, oxcarbazepine and eslicarbazepine acetate in the real world].
    Revista de neurologia, 2020, Jul-16, Volume: 71, Issue:2

    Topics: Adult; Aged; Alanine Transaminase; Anticonvulsants; Aspartate Aminotransferases; Carbamazepine; Dibenzazepines; Epilepsies, Partial; Female; Follow-Up Studies; gamma-Glutamyltransferase; Healthy Lifestyle; Humans; Hyponatremia; Leukocyte Count; Lipids; Male; Metabolism; Middle Aged; Nerve Tissue Proteins; Oxcarbazepine; Retrospective Studies; Sodium; Voltage-Gated Sodium Channels

2020
Distinct effects on cAMP signaling of carbamazepine and its structural derivatives do not correlate with their clinical efficacy in epilepsy.
    European journal of pharmacology, 2020, Nov-05, Volume: 886

    Topics: Adenylyl Cyclases; Anticonvulsants; Calcium Signaling; Carbamazepine; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Dibenzazepines; Epilepsy; HEK293 Cells; Humans; Oxcarbazepine; Seizures; Signal Transduction; Treatment Outcome

2020