eseroline has been researched along with physostigmine in 14 studies
| Studies (eseroline) | Trials (eseroline) | Recent Studies (post-2010) (eseroline) | Studies (physostigmine) | Trials (physostigmine) | Recent Studies (post-2010) (physostigmine) |
|---|---|---|---|---|---|
| 29 | 0 | 1 | 6,230 | 252 | 331 |
| Protein | Taxonomy | eseroline (IC50) | physostigmine (IC50) |
|---|---|---|---|
| Acetylcholinesterase | Electrophorus electricus (electric eel) | 0.1666 | |
| Acetylcholinesterase | Tetronarce californica (Pacific electric ray) | 0.3023 | |
| Cholinesterase | Homo sapiens (human) | 0.3055 | |
| Cytochrome P450 2D6 | Homo sapiens (human) | 0.2 | |
| Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | 0.857 | |
| Acetylcholinesterase | Mus musculus (house mouse) | 0.0269 | |
| Acetylcholinesterase | Homo sapiens (human) | 0.0853 | |
| Acetylcholinesterase | Bos taurus (cattle) | 0.7197 | |
| Alpha-1D adrenergic receptor | Rattus norvegicus (Norway rat) | 0.857 | |
| Delta-type opioid receptor | Mus musculus (house mouse) | 1.1821 | |
| Acetylcholinesterase | Gallus gallus (chicken) | 0.02 | |
| Acetylcholinesterase | Rattus norvegicus (Norway rat) | 0.0416 | |
| Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | 0.857 | |
| Cholinesterase | Equus caballus (horse) | 0.4081 | |
| Cholinesterase | Mus musculus (house mouse) | 0.28 | |
| Acyl-CoA:cholesterol acyltransferase | Oryctolagus cuniculus (rabbit) | 0.0189 | |
| Carboxylic ester hydrolase | Rattus norvegicus (Norway rat) | 0.018 | |
| Carboxylic ester hydrolase | Equus caballus (horse) | 1.263 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (42.86) | 18.7374 |
| 1990's | 4 (28.57) | 18.2507 |
| 2000's | 3 (21.43) | 29.6817 |
| 2010's | 1 (7.14) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Brossi, A; Greig, NH; Holloway, HW; Yu, Q | 1 |
| Bartolini, A; Bartolini, R; Galli, A; Malmberg-Aiello, P; Renzi, G | 1 |
| Quinn, KD; Stewart, JT | 1 |
| Lawrence, GD; Yatim, N | 1 |
| Krishna, G; Kutty, RK; Somani, SM | 1 |
| Brossi, A; Flippen-Anderson, JL; Gilardi, R; Jacobson, AE; Klee, WA; Schönenberger, B; Streaty, R | 1 |
| Atack, JR; Brossi, A; Rapoport, SI; Yu, QS | 1 |
| Downen, M; Giacobini, E; Hallak, M; McIlhany, M; Somani, S | 1 |
| Brossi, A; Clark, OE; Ray, R; Schönenberger, B | 1 |
| Aiello-Malmberg, P; Bartolini, A; Bartolini, R; Galli, A; Grazzini, E; Renzi, G | 1 |
| Chen, JL; Chiang, CH; Yeh, MK | 1 |
| Chaw, CS; Moochhala, SM; Yang, YY; Zhao, B | 1 |
| Golicnik, M; Stojan, J | 1 |
| Brenner, T; Gubbe, U; Hofer, S; Hoppe-Tichy, T; Pinder, N; Swoboda, S; Weigand, MA; Zimmermann, JB | 1 |
14 other study(ies) available for eseroline and physostigmine
| Article | Year |
|---|---|
Syntheses and anticholinesterase activities of (3aS)-N1, N8-bisnorphenserine, (3aS)-N1,N8-bisnorphysostigmine, their antipodal isomers, and other potential metabolites of phenserine.
Topics: Acetylcholinesterase; Butyrylcholinesterase; Carbamates; Cholinesterase Inhibitors; Erythrocytes; Humans; Hydrolysis; In Vitro Techniques; Indoles; Oxidation-Reduction; Phenylcarbamates; Physostigmine; Stereoisomerism; Structure-Activity Relationship | 1998 |
Inhibition of [3H]naloxone binding in homogenates of rat brain by eseroline, a drug, with analgesic activity, related to physostigmine.
Topics: Analgesics; Animals; Binding, Competitive; Brain; In Vitro Techniques; Indoles; Kinetics; Naloxone; Physostigmine; Rats; Receptors, Opioid | 1979 |
A high performance liquid chromatographic post-column fluorescent ion pair extraction system: application to physostigmine and its metabolite eseroline in human serum.
Topics: Benzenesulfonates; Chromatography, High Pressure Liquid; Fluorescent Dyes; Humans; Indoles; Nitriles; Physostigmine | 1991 |
Extraction of physostigmine from biologic fluids and analysis by liquid chromatography with electrochemical detection.
Topics: Chromatography, High Pressure Liquid; Electrochemistry; Humans; Indoles; Physostigmine | 1990 |
Eseroline, a metabolite of physostigmine, induces neuronal cell death.
Topics: Adenine Nucleotides; Adenosine Triphosphate; Animals; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Indoles; L-Lactate Dehydrogenase; Mice; Neurons; Physostigmine | 1990 |
Comparison of (-)-eseroline with (+)-eseroline and dihydroseco analogues in antinociceptive assays: confirmation of rubreserine structure by X-ray analysis.
Topics: Adenylyl Cyclase Inhibitors; Analgesics; Animals; In Vitro Techniques; Indoles; Physostigmine; Rats; Receptors, Opioid; Stereoisomerism; Structure-Activity Relationship; X-Ray Diffraction | 1986 |
Carbamate analogues of (-)-physostigmine: in vitro inhibition of acetyl- and butyrylcholinesterase.
Topics: Acetylcholinesterase; Animals; Butyrylcholinesterase; Carbamates; Chemical Phenomena; Chemistry; Cholinesterase Inhibitors; Electrophorus; Humans; Indoles; Physostigmine | 1988 |
Pharmacokinetics and pharmacodynamics of physostigmine after intravenous administration in beagle dogs.
Topics: Animals; Body Water; Brain; Cholinesterases; Dogs; Half-Life; Humans; Indoles; Injections, Intravenous; Male; Mathematics; Physostigmine; Rats; Tissue Distribution | 1987 |
Inhibition of acetylcholinesterase from electric eel by (-)-and (+)-physostigmine and related compounds.
Topics: Acetylcholinesterase; Animals; Cholinesterase Inhibitors; Eels; Indoles; Physostigmine; Structure-Activity Relationship | 1986 |
Reversible inhibition of acetylcholinesterase by eseroline, an opioid agonist structurally related to physostigmine (eserine) and morphine.
Topics: Animals; Cholinesterase Inhibitors; Electric Stimulation; Electrophorus; Guinea Pigs; Horses; Humans; Ileum; In Vitro Techniques; Indoles; Kinetics; Morphine Derivatives; Muscle Contraction; Muscle, Smooth; Physostigmine; Rats; Rats, Inbred Strains; Structure-Activity Relationship | 1982 |
Anaerobic stability of aqueous physostigmine solution.
Topics: Anaerobiosis; Cholinesterase Inhibitors; Chromatography, High Pressure Liquid; Drug Stability; Hydrogen-Ion Concentration; Indoles; Kinetics; Oxygen; Physostigmine; Solutions; Spectrophotometry, Ultraviolet; Temperature; Thermodynamics; Water | 2000 |
Simple liquid chromatographic method for the determination of physostigmine and its metabolite eseroline in rat plasma: application to a pharmacokinetic study.
Topics: Animals; Cholinesterase Inhibitors; Chromatography, Liquid; Indoles; Male; Physostigmine; Rats; Rats, Sprague-Dawley; Reproducibility of Results | 2003 |
Transient kinetic approach to the study of acetylcholinesterase reversible inhibition by eseroline.
Topics: Acetylcholinesterase; Analgesics, Opioid; Animals; Binding Sites; Cholinesterase Inhibitors; Electrophorus; Indoles; Kinetics; Mathematics; Models, Chemical; Physostigmine; Substrate Specificity | 2002 |
Revival of physostigmine - a novel HPLC assay for simultaneous determination of physostigmine and its metabolite eseroline designed for a pharmacokinetic study of septic patients.
Topics: Chromatography, High Pressure Liquid; Healthy Volunteers; Humans; Indoles; Liquid-Liquid Extraction; Physostigmine; Shock, Septic | 2015 |