esermethole and phenserine

esermethole has been researched along with phenserine* in 1 studies

Other Studies

1 other study(ies) available for esermethole and phenserine

Article	Year
Palladium-catalyzed enantioselective C-3 allylation of 3-substituted-1H-indoles using trialkylboranes. Journal of the American Chemical Society, 2006, May-17, Volume: 128, Issue:19 We have developed a new enantioselective C-3 allylation of 3-substituted indoles using allyl alcohol and trialkylboranes. Asymmetric syntheses of 3,3-disubstituted indolines and indolenines in enantiomeric excesses up to 90% have been achieved using the bulky borane 9-BBN-C6H13 as the promoter of the reaction. The dependence of the selectivity on the nature of the borane suggests that the boron reagent has a role beyond promoting ionization of the allyl alcohol. A protocol for oxidation of indolenines to oxindoles has also been developed and led to a formal synthesis of (-)-phenserine. Topics: Alkenes; Boranes; Catalysis; Indoles; Palladium; Physostigmine; Stereoisomerism	2006

Article

Year

Palladium-catalyzed enantioselective C-3 allylation of 3-substituted-1H-indoles using trialkylboranes.

Journal of the American Chemical Society, 2006, May-17, Volume: 128, Issue:19

We have developed a new enantioselective C-3 allylation of 3-substituted indoles using allyl alcohol and trialkylboranes. Asymmetric syntheses of 3,3-disubstituted indolines and indolenines in enantiomeric excesses up to 90% have been achieved using the bulky borane 9-BBN-C6H13 as the promoter of the reaction. The dependence of the selectivity on the nature of the borane suggests that the boron reagent has a role beyond promoting ionization of the allyl alcohol. A protocol for oxidation of indolenines to oxindoles has also been developed and led to a formal synthesis of (-)-phenserine.

Topics: Alkenes; Boranes; Catalysis; Indoles; Palladium; Physostigmine; Stereoisomerism

2006