erythrosine has been researched along with methotrexate in 50 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 18 (36.00) | 18.7374 |
| 1990's | 11 (22.00) | 18.2507 |
| 2000's | 15 (30.00) | 29.6817 |
| 2010's | 6 (12.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cramer, PL; Gapski, GR; Henderson, GB; Huennekens, FM; Neef, V; Rader, JI; Whiteley, JM | 1 |
| Allen, CN; Collington, GK; Hirst, BH; Simmons, NL | 1 |
| Freisheim, JH; Hynes, JB; Jansen, G; Kerwar, SS; McAlinden, TP; Patil, SA; Schornagel, JH; Westerhof, GR | 1 |
| Daniel, J; Dyson, JE; McLaughlin, JB; Simmons, DM; Surrey, CR | 1 |
| Assaraf, YG; Molina, A; Schimke, RT | 2 |
| Assaraf, YG; Schimke, RT; Seamer, LC | 1 |
| Barnett, PA; Carney, DN; D'Agostino, AN; Frenkel, EP; McCormick, CI; Minna, JD; Neuwelt, EA | 1 |
| Kerwar, SS; Webber, S; Whiteley, JM | 1 |
| Rybak, LP | 1 |
| Barbet, J; Lemonnier, FA; Leserman, LD; Machy, P; Mishal, Z; Truneh, A | 1 |
| Midoux, P; Monsigny, M; Roche, AC | 1 |
| Ishizaki, Y; Nishiya, I; Nunokawa, S; Saitoh, S; Yamashita, K | 1 |
| Koch, U; Pau, HW; Straehler-Pohl, HJ | 1 |
| Henderson, GB; Russell, A; Whiteley, JM | 1 |
| Barbet, J; Leserman, LD; Machy, P; Pierres, M | 1 |
| Leserman, LD; Machy, P | 1 |
| Leserman, LD; Moore, JJ; Terry, WD; Weinstein, JN | 1 |
| Masereeuw, R; Miller, DS; Russel, FG | 1 |
| Bertino, JR; Elisseyeff, Y; Flintoff, WF; Goker, E; Gorlick, R; Mazumdar, M; Steinherz, P; Trippett, T | 1 |
| Audus, KL; Avery, M; Liu, F; Shi, F; Soares, MJ; Zhang, X | 1 |
| Fan, J; Huennekens, FM | 1 |
| Miller, DS; Pritchard, JB | 1 |
| Michnick, SW; Remy, I; Wilson, IA | 1 |
| Bebawy, M; Morris, MB; Roufogalis, BD | 1 |
| Michnick, SW; Remy, I | 1 |
| Drewe, J; Fricker, G; Gutmann, H; Miller, DS; Toeroek, M | 1 |
| Masereeuw, R; Miller, DS; Russel, FG; Terlouw, SA; van Aubel, RA | 1 |
| Masereeuw, R; Miller, DS; Russel, FG; Terlouw, SA | 1 |
| Katakura, Y; Kishimoto, M; Nakanishi, F; Ogura, Y; Oi, D; Omasa, T; Suga, KI; Yoshikawa, T | 1 |
| Miller, DS | 1 |
| Becker, A; Bode, U; Jaehde, U; Scheuch, E | 1 |
| Borst, P; Burg, D; Mulder, GJ; Saeki, T; Wielinga, P; Zelcer, N | 1 |
| Assaraf, YG; Dijkmans, BA; Hooijberg, JH; Ifergan, I; Jansen, G; Kathmann, I; Peters, GJ; Rothem, L; Stark, M | 1 |
| Deutsch, M; Ehrenfeld, M; Herman, S; Langevitz, P; Zurgil, N | 1 |
| Assaraf, YG; Goldman, ID; Jansen, G; Rothem, L; Scheffer, GL; Stark, M | 1 |
| COLEMAN, V; CORWIN, ME; JAWETZ, E; OKUMOTO, M; RIEGELMAN, S; THYGESON, P | 1 |
| Baehr, C; Breen, CM; Fricker, G; Miller, DS; Sykes, DB | 1 |
| Cruysberg, LP; Edelhauser, HF; Geroski, DH; Gilbert, JA; Hendrikse, F; Nuijts, RM | 1 |
| Chen, V; Dantzig, AH; Perry, WI; Pratt, S; Starling, JJ | 1 |
| Baehr, CH; Fricker, G; Miller, DS | 1 |
| Barnaby, R; Hamilton, JW; Karlson, KH; Miller, DS; Shaw, JR; Stanton, BA; Stanton, CR | 1 |
| Bai, KB; Hudecz, F; Köhidai, L; Láng, O; Mezö, G; Orbán, E; Szabó, R | 1 |
| Ayric, Z; Blau, N; Blom, H; Bode, H; Cario, H; Debatin, KM; Holzmann, K; Hopfner, KP; Kohne, E; Pannicke, U; Rump, EM; Schwarz, K; Smith, DE; Smulders, Y | 1 |
| Hagesaether, E | 1 |
| Heilmann, K; Messerschmidt, K | 1 |
| Infante, MR; Mitjans, M; Nogueira, DR; Pérez, L; Tavano, L; Vinardell, MP | 1 |
| Algarve, TD; Azzolin, V; Barbisan, F; da Cruz, IB; Dornelles, EB; Duarte, MM; Marcon, M; Mostardeiro, CP; Motta, Jde R; Schott, KL; Trott, A; Unfer, TC | 1 |
| Deng, P; Junger, WG; Qi, B; Sun, D; Wang, C; Wang, T; Xia, Y; Yao, J; Yu, T; Zhang, X | 1 |
3 review(s) available for erythrosine and methotrexate
| Article | Year |
|---|---|
Organic acid transport into the cochlear perilymph.
Topics: Acids; Animals; Anti-Bacterial Agents; Cochlea; Fluorescein; Fluoresceins; Furosemide; Labyrinthine Fluids; Methotrexate; Perilymph; Salicylates | 1987 |
Dual pathways for organic anion secretion in renal proximal tubule.
Topics: Animals; Biological Transport; Fishes; Fluoresceins; Ion Pumps; Kidney Tubules, Proximal; Methotrexate; Organic Chemicals; Ouabain | 1997 |
Xenobiotic export pumps, endothelin signaling, and tubular nephrotoxicants--a case of molecular hijacking.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Calcium; Endothelins; Fluoresceins; Kidney Tubules, Proximal; Killifishes; Membrane Transport Proteins; Methotrexate; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Nitric Oxide; Protein Kinase C; Receptor, Endothelin B; Receptors, Endothelin; Signal Transduction; Xenobiotics | 2002 |
47 other study(ies) available for erythrosine and methotrexate
| Article | Year |
|---|---|
Synthesis of a fluorescent derivative of amethopterin,.
Topics: Animals; Biological Transport; Depression, Chemical; Diamines; Fluoresceins; Fluorescence; Folic Acid Antagonists; Lacticaseibacillus casei; Leukemia L1210; Methotrexate; Spectrophotometry, Ultraviolet; Thiocyanates | 1975 |
Pharmacological profile of inhibition of 2',7'-bis(2-carboxyethyl)-5(6)-carboxyfluorescein efflux in human HCT-8 intestinal epithelial cells.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Adenosine Triphosphate; Biological Transport; Dose-Response Relationship, Drug; Epithelium; Fluoresceins; Humans; Hydrogen-Ion Concentration; Indomethacin; Intestinal Neoplasms; Methotrexate; Nitrobenzoates; Spectrometry, Fluorescence; Tumor Cells, Cultured; Vinblastine | 1991 |
Synthesis and biological evaluation of a fluorescent analogue of folic acid.
Topics: Binding, Competitive; Biological Transport; Carrier Proteins; Cell Line; Flow Cytometry; Fluoresceins; Fluorescence; Fluorescent Dyes; Folate Receptors, GPI-Anchored; Folic Acid; Humans; Lysine; Methotrexate; Placenta; Receptors, Cell Surface; Substrate Specificity; Tetrahydrofolate Dehydrogenase; Tumor Cells, Cultured | 1991 |
Effects of hyperthermia, irradiation, and cytotoxic drugs on fluorescein isothiocyanate staining intensity for flow cytofluorometry.
Topics: Antineoplastic Agents; Cell Cycle; Cell Line; Cell Nucleus; Cell Survival; Computers; Doxorubicin; Flow Cytometry; Fluorescein-5-isothiocyanate; Fluoresceins; Hot Temperature; Humans; Kinetics; Methotrexate; Proteins; Staining and Labeling; Thiocyanates | 1987 |
A fluorescein-methotrexate-based flow cytometric bioassay for measurement of plasma methotrexate and trimetrexate levels.
Topics: Flow Cytometry; Fluorescein; Fluoresceins; Humans; Indicators and Reagents; Methotrexate; Quinazolines; Trimetrexate | 1989 |
Sequential amplification of dihydrofolate reductase and multidrug resistance genes in Chinese hamster ovary cells selected for stepwise resistance to the lipid-soluble antifolate trimetrexate.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line; Cricetinae; Drug Resistance; Fluorescein; Fluoresceins; Folic Acid Antagonists; Gene Amplification; Gene Expression; Membrane Glycoproteins; Methotrexate; Pyrimidines; Quinazolines; RNA, Messenger; Tetrahydrofolate Dehydrogenase; Trimetrexate | 1989 |
Characterization by flow cytometry of fluorescein-methotrexate transport in Chinese hamster ovary cells.
Topics: Animals; Cells, Cultured; Cricetinae; Cricetulus; Female; Flow Cytometry; Fluoresceins; Methotrexate; Ovary | 1989 |
Growth of human lung tumor in the brain of the nude rat as a model to evaluate antitumor agent delivery across the blood-brain barrier.
Topics: Animals; Antineoplastic Agents; Blood-Brain Barrier; Brain Neoplasms; Carcinoma, Small Cell; Cell Line; Evans Blue; Fluoresceins; Humans; Lung Neoplasms; Methotrexate; Models, Biological; Neoplasm Transplantation; Rats; Rats, Inbred Strains | 1985 |
Synthesis and efficient isolation procedure for gamma-linked fluorescein methotrexate.
Topics: Animals; Chemical Phenomena; Chemistry; Chromatography, DEAE-Cellulose; Chromatography, High Pressure Liquid; Fluorescein-5-isothiocyanate; Fluoresceins; Folic Acid Antagonists; Liver; Methotrexate; Rats; Spectrum Analysis; Structure-Activity Relationship; Thiocyanates | 1986 |
Intra-arterial infusion for head and neck cancers.
Topics: Aged; Antineoplastic Agents; Brachiocephalic Trunk; Carcinoma, Squamous Cell; Carotid Arteries; Catheterization; Female; Fluoresceins; Fluorouracil; Head; Head and Neck Neoplasms; Humans; Injections, Intra-Arterial; Leukocyte Count; Male; Methods; Methotrexate; Neoplasm Recurrence, Local; Neoplasms; Vinblastine | 1973 |
Endocytosis of HLA and H-2 molecules on transformed murine cells measured by fluorescence dequenching of liposome-encapsulated carboxyfluorescein.
Topics: Animals; Antibodies, Monoclonal; Cell Transformation, Viral; Endocytosis; Epitopes; Fluoresceins; H-2 Antigens; HeLa Cells; HLA Antigens; Humans; L Cells; Liposomes; Major Histocompatibility Complex; Methotrexate; Mice; Simian virus 40; Spectrometry, Fluorescence | 1983 |
Uptake of neoglycoproteins via membrane lectin(s) of L1210 cells evidenced by quantitative flow cytofluorometry and drug targeting.
Topics: Animals; Cell Membrane; Cell Survival; Flow Cytometry; Fluorescein-5-isothiocyanate; Fluoresceins; Fluorescent Dyes; Glycated Serum Albumin; Glycation End Products, Advanced; Hydrogen-Ion Concentration; Lectins; Leukemia L1210; Methotrexate; Mice; Serum Albumin; Thiocyanates | 1984 |
[Cell functions of cultured human choriocarcinoma following the administration of methotrexate (author's transl)].
Topics: Cell Cycle; Cells, Cultured; Choriocarcinoma; Chorionic Gonadotropin; DNA, Neoplasm; Female; Flow Cytometry; Fluorescein-5-isothiocyanate; Fluoresceins; Humans; Methotrexate; Pregnancy; Thiocyanates; Trophoblastic Neoplasms; Uterine Neoplasms | 1981 |
[Photodocumentation of intra-arterial infusions using fluorescein].
Topics: Catheterization; Fluorescein; Fluoresceins; Humans; Infusions, Intra-Arterial; Methotrexate; Mouth Neoplasms; Pharyngeal Neoplasms | 1983 |
A fluorescent derivative of methotrexate as an intracellular marker for dihydrofolate reductase in L1210 cells.
Topics: Animals; Biological Transport; Drug Resistance; Fluorescein-5-isothiocyanate; Fluoresceins; Fluorescent Dyes; Folic Acid Antagonists; Kinetics; Leukemia L1210; Methotrexate; Mice; Protein Binding; Thiocyanates | 1980 |
Drug transfer into lymphoblasts mediated by liposomes bound to distinct sites on H-2 encoded I-A, I-E, and K molecules.
Topics: Animals; B-Lymphocytes; Fluoresceins; Fluorescent Antibody Technique; Genes, MHC Class II; H-2 Antigens; Histocompatibility Antigens; Histocompatibility Antigens Class II; Isoantibodies; Liposomes; Lymphocyte Activation; Methotrexate; Mice; Mice, Inbred CBA; Staphylococcal Protein A; T-Lymphocytes | 1982 |
Small liposomes are better than large liposomes for specific drug delivery in vitro.
Topics: Animals; Antibodies, Monoclonal; Chemical Phenomena; Chemistry, Physical; Chromatography, Gel; Endocytosis; Fluoresceins; Liposomes; Methotrexate; Mice; Microscopy, Fluorescence; Staphylococcal Protein A | 1983 |
Specific interaction of myeloma tumor cells with hapten-bearing liposomes containing methotrexate and carboxyfluorescein.
Topics: Animals; DNA, Neoplasm; Fluoresceins; Haptens; Liposomes; Methotrexate; Mice; Plasmacytoma; Receptors, Antigen, B-Cell; Tetrahydrofolate Dehydrogenase | 1980 |
Multiple pathways of organic anion secretion in renal proximal tubule revealed by confocal microscopy.
Topics: Animals; Anions; Biological Transport; Fluorescein; Fluoresceins; Kidney Tubules, Proximal; Killifishes; Methotrexate; Microscopy, Confocal; Rhodamines; Sodium | 1996 |
Defective transport is a common mechanism of acquired methotrexate resistance in acute lymphocytic leukemia and is associated with decreased reduced folate carrier expression.
Topics: Adolescent; Adult; Aged; Biological Transport; Blast Crisis; Carrier Proteins; Child; Child, Preschool; Drug Resistance; Fluoresceins; Folic Acid; Humans; Membrane Proteins; Membrane Transport Proteins; Methotrexate; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Reduced Folate Carrier Protein | 1997 |
Permeability and metabolic properties of a trophoblast cell line (HRP-1) derived from normal rat placenta.
Topics: Animals; Biological Transport; Biomarkers; Carbon Radioisotopes; Cell Culture Techniques; Cell Line; Cell Membrane Permeability; Cytochrome P-450 CYP1A1; Dermatologic Agents; Dextrans; Female; Fluorescein; Fluoresceins; Humans; Linoleic Acid; Linoleic Acids; Mannitol; Methotrexate; Microsomes; Oxazines; Rats; Sucrose; Transferrin; Trophoblasts; Urea | 1997 |
Biotin derivatives of folate compounds: synthesis and utilization for visualization and affinity purification of folate transport proteins.
Topics: Animals; Bacterial Proteins; Biological Transport; Biotin; Carrier Proteins; Chromatography, Affinity; Electrophoresis, Polyacrylamide Gel; Fluorescein; Fluoresceins; Folate Receptors, GPI-Anchored; Folic Acid; Leukemia L1210; Methotrexate; Microscopy; Molecular Structure; Receptors, Cell Surface; Sepharose; Tumor Cells, Cultured | 1997 |
Erythropoietin receptor activation by a ligand-induced conformation change.
Topics: Animals; CHO Cells; COS Cells; Cricetinae; Dimerization; Erythropoietin; Flow Cytometry; Fluoresceins; Janus Kinase 2; Ligands; Methotrexate; Microscopy, Fluorescence; Peptides, Cyclic; Protein Conformation; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Receptors, Erythropoietin; Recombinant Fusion Proteins; Tetrahydrofolate Dehydrogenase; Transfection | 1999 |
A continuous fluorescence assay for the study of P-glycoprotein-mediated drug efflux using inside-out membrane vesicles.
Topics: Adenosine Triphosphate; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport, Active; Cell Membrane; Colchicine; Drug Resistance, Multiple; Fluoresceins; Humans; Kinetics; Methotrexate; Methylene Blue; Sodium-Potassium-Exchanging ATPase; Spectrometry, Fluorescence; Tumor Cells, Cultured; Vinblastine | 1999 |
Clonal selection and in vivo quantitation of protein interactions with protein-fragment complementation assays.
Topics: Animals; Carrier Proteins; Cell Survival; CHO Cells; Cricetinae; Erythropoietin; Flow Cytometry; Fluoresceins; Genetic Complementation Test; Immunophilins; Methotrexate; Mice; Microscopy, Fluorescence; Peptides, Cyclic; Phosphotransferases (Alcohol Group Acceptor); Protein Binding; Receptors, Erythropoietin; Recombinant Fusion Proteins; Sirolimus; Tacrolimus; Tacrolimus Binding Proteins; Tetrahydrofolate Dehydrogenase; TOR Serine-Threonine Kinases; Transfection | 1999 |
Interactions of HIV protease inhibitors with ATP-dependent drug export proteins.
Topics: Adenosine Triphosphatases; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Cyclosporine; Fluoresceins; HIV Protease Inhibitors; Killifishes; Methotrexate; Mitochondrial Proteins; Ribosomal Proteins; Ritonavir; Saccharomyces cerevisiae Proteins; Saquinavir | 1999 |
Endothelin B receptor-mediated regulation of ATP-driven drug secretion in renal proximal tubule.
Topics: Adenosine Triphosphate; Animals; Anion Transport Proteins; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Carrier Proteins; Cyclosporine; Endothelins; Fluoresceins; Iohexol; Kidney Tubules, Proximal; Killifishes; Methotrexate; Protein Kinase C; Receptor, Endothelin B; Receptors, Endothelin | 2000 |
Nephrotoxicants induce endothelin release and signaling in renal proximal tubules: effect on drug efflux.
Topics: Animals; Biological Transport; Calcium; Endothelins; Energy Metabolism; Fluoresceins; Kidney Tubules, Proximal; Killifishes; Methotrexate; Signal Transduction; Tetradecanoylphorbol Acetate | 2001 |
Flow cytometry: an improved method for the selection of highly productive gene-amplified CHO cells using flow cytometry.
Topics: Animals; Antigens, Surface; Cell Separation; CHO Cells; Cricetinae; Flow Cytometry; Fluoresceins; Gene Amplification; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; In Situ Hybridization, Fluorescence; Methotrexate; Tetrahydrofolate Dehydrogenase | 2001 |
Simultaneous analysis of sulfur-containing excitatory amino acids using micellar electrokinetic chromatography with diode array and laser-induced fluorescence detection.
Topics: Amino Acids, Sulfur; Antimetabolites, Antineoplastic; Central Nervous System; Chromatography, Micellar Electrokinetic Capillary; Drug Stability; Excitatory Amino Acids; Fluoresceins; Fluorescent Dyes; Humans; Hydrogen-Ion Concentration; Lasers; Methotrexate; Sensitivity and Specificity; Spectrometry, Fluorescence; Succinimides | 2002 |
Inhibition of the multidrug resistance protein 1 (MRP1) by peptidomimetic glutathione-conjugate analogs.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Cell Division; Cells, Cultured; Estradiol; Fluoresceins; Glucuronides; Glutathione; Insecta; Kinetics; Methotrexate; Peptides; Tritium | 2002 |
Loss of multidrug resistance protein 1 expression and folate efflux activity results in a highly concentrative folate transport in human leukemia cells.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Blotting, Western; Cell Division; Cell Line; Cell Membrane; Flow Cytometry; Fluoresceins; Folic Acid; Humans; Leucovorin; Methotrexate; Microscopy, Fluorescence; Mutation; Time Factors; Tumor Cells, Cultured | 2003 |
The induction of apoptosis by methotrexate in activated lymphocytes as indicated by fluorescence hyperpolarization: a possible model for predicting methotrexate therapy for rheumatoid arthritis patients.
Topics: Adult; Aged; Aged, 80 and over; Antirheumatic Agents; Apoptosis; Arthritis, Rheumatoid; Cells, Cultured; Drug Resistance; Female; Fluoresceins; Fluorescence Polarization; Fluorescence Polarization Immunoassay; Fluorometry; Humans; Lymphocyte Activation; Lymphocytes; Male; Methotrexate; Middle Aged; Models, Biological; Predictive Value of Tests; Reaction Time; Reproducibility of Results | 2003 |
Antifolate resistance associated with loss of MRP1 expression and function in Chinese hamster ovary cells with markedly impaired export of folate and cholate.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Cell Division; Cells, Cultured; CHO Cells; Cholates; Cricetinae; Drug Resistance; Flow Cytometry; Fluoresceins; Folic Acid; Humans; Methotrexate; Multidrug Resistance-Associated Proteins; Prostaglandins A; Pyrimethamine; Tritium | 2003 |
EFFECT OF IUDR AND AMETHOPTERIN ON EXPERIMENTAL HERPES SIMPLEX KERATITIS.
Topics: Animals; Fluoresceins; Idoxuridine; Keratitis; Keratitis, Dendritic; Keratitis, Herpetic; Lagomorpha; Methotrexate; Pharmacology; Rabbits; Research; Tissue Culture Techniques | 1963 |
Fluorescein-methotrexate transport in rat choroid plexus analyzed using confocal microscopy.
Topics: Animals; Biological Transport; Bronchodilator Agents; Choroid Plexus; Digoxin; Enzyme Inhibitors; Epithelial Cells; Fluoresceins; Male; Methotrexate; Microscopy, Confocal; Organic Anion Transporters; Propionates; Quinolines; Rats; Rats, Sprague-Dawley | 2004 |
In vitro sustained human transscleral drug delivery of fluorescein-labeled dexamethasone and methotrexate with fibrin sealant.
Topics: Dexamethasone; Diffusion Chambers, Culture; Drug Delivery Systems; Fibrin Tissue Adhesive; Fluorescein; Fluoresceins; Glucocorticoids; Humans; Methotrexate; Middle Aged; Permeability; Sclera; Tissue Adhesives | 2005 |
Kinetic validation of the use of carboxydichlorofluorescein as a drug surrogate for MRP5-mediated transport.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Antimetabolites, Antineoplastic; Cyclic Nucleotide Phosphodiesterases, Type 5; Fluoresceins; Fluorescent Dyes; Glutamates; Guanine; HeLa Cells; Humans; Kinetics; Membrane Transport Proteins; Methotrexate; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Pemetrexed; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Probenecid; Propionates; Quinolines; Reproducibility of Results; Staining and Labeling; Transfection | 2006 |
Fluorescein-methotrexate transport in dogfish shark (Squalus acanthias) choroid plexus.
Topics: Animals; Biological Transport; Choroid Plexus; Dogfish; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fluoresceins; Methotrexate; Microscopy, Confocal; Organic Anion Transporters; Protein Kinases | 2006 |
MRP2 and acquired tolerance to inorganic arsenic in the kidney of killifish (Fundulus heteroclitus).
Topics: Animals; Arsenites; Dose-Response Relationship, Drug; Drug Tolerance; Fluoresceins; Fluorescent Dyes; Fundulidae; Kidney Tubules, Proximal; Membrane Potential, Mitochondrial; Membrane Transport Proteins; Methotrexate; Mitochondria; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Protein Processing, Post-Translational; RNA, Messenger; Sodium Compounds; Tissue Distribution; Up-Regulation; Water Pollutants, Chemical | 2007 |
Design, synthesis, and in vitro activity of novel drug delivery systems containing tuftsin derivatives and methotrexate.
Topics: Amino Acid Sequence; Antineoplastic Agents; Apoptosis; Cathepsin B; Cell Line; Chemotaxis; Drug Carriers; Drug Design; Endocytosis; Fluoresceins; Humans; Methotrexate; Staining and Labeling; Tuftsin | 2008 |
Dihydrofolate reductase deficiency due to a homozygous DHFR mutation causes megaloblastic anemia and cerebral folate deficiency leading to severe neurologic disease.
Topics: Anemia, Megaloblastic; Child; Child, Preschool; Erythrocytes; Female; Fluoresceins; Folic Acid; Folic Acid Deficiency; Homozygote; Humans; Male; Methotrexate; Models, Molecular; Mutation; Nervous System Diseases; Pedigree; Protein Conformation; Tetrahydrofolate Dehydrogenase | 2011 |
Permeation modulating properties of natural polymers--effect of molecular weight and mucus.
Topics: Chitosan; Excipients; Fluoresceins; Fluorescent Dyes; Goblet Cells; HT29 Cells; Humans; Hyaluronic Acid; Methotrexate; Molecular Weight; Mucus; Pectins; Permeability; Polymers | 2011 |
Toxin-antigen conjugates as selection tools for antibody producing cells.
Topics: Animals; Antibodies; Antibodies, Monoclonal; Antibody-Producing Cells; Antigens; Cell Survival; Dose-Response Relationship, Drug; Fluoresceins; Hybridomas; Immunologic Techniques; Immunotoxins; Methotrexate; Mice; Mice, Inbred BALB C; Ovalbumin; Reproducibility of Results | 2013 |
In vitro antitumor activity of methotrexate via pH-sensitive chitosan nanoparticles.
Topics: Antimetabolites, Antineoplastic; Apoptosis; Cell Cycle; Cell Survival; Chemical Phenomena; Chitosan; Drug Delivery Systems; Feasibility Studies; Fluoresceins; HeLa Cells; Humans; Hydrogen-Ion Concentration; Lysine; MCF-7 Cells; Methotrexate; Microscopy, Fluorescence; Nanoparticles; Surface-Active Agents | 2013 |
Methotrexate-related response on human peripheral blood mononuclear cells may be modulated by the Ala16Val-SOD2 gene polymorphism.
Topics: Antioxidants; Caspases; Cytokines; Dose-Response Relationship, Drug; Fluoresceins; Gene Expression Regulation, Enzymologic; Humans; Lipid Peroxidation; Methotrexate; Polymorphism, Single Nucleotide; Protein Carbonylation; Reactive Oxygen Species; RNA, Messenger; Superoxide Dismutase | 2014 |
Shock wave-induced ATP release from osteosarcoma U2OS cells promotes cellular uptake and cytotoxicity of methotrexate.
Topics: Adenosine Triphosphate; Antimetabolites, Antineoplastic; Bone Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Extracorporeal Shockwave Therapy; Fluoresceins; Humans; Methotrexate; Osteosarcoma; Receptors, Purinergic P2X7 | 2016 |