erythrosine has been researched along with cyclosporine in 75 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 26 (34.67) | 18.2507 |
| 2000's | 32 (42.67) | 29.6817 |
| 2010's | 16 (21.33) | 24.3611 |
| 2020's | 1 (1.33) | 2.80 |
| Authors | Studies |
|---|---|
| Ichimura, K; Kashiwagura, T; Kawahara, K; Koike, M; Matsui, W; Takeguchi, N | 1 |
| Bernardi, P; Nicolli, A; Petronilli, V | 1 |
| Coleman, R; Román, ID | 1 |
| Brezden, CB; Hedley, DW; Rauth, AM | 1 |
| Larsson, R; Liminga, G; Nygren, P | 1 |
| Benítez del Castillo, JM; del Aguila, C; Duran, S; García Sánchez, J; Hernandez, J | 1 |
| Acosta, D; Jiang, T | 1 |
| Amador, A; Kahan, BD; Rutzky, LP; Welsh, M | 1 |
| Coleman, R; Johnson, GD; Román, ID | 1 |
| Benítez del Castillo, JM; Castillo, A; del Aguila, C; Durán, S; García-Sanchez, J; Otero, M; Toledano, N | 1 |
| Ford, PJ; Germann, UA; Harding, MW; Mason, VS; Shlyakhter, D | 1 |
| Csoka, K; Dhar, S; Fridborg, H; Jonsson, B; Larsson, R; Liminga, G; Nygren, P | 1 |
| Allain, F; Denys, A; Foxwell, B; Spik, G | 1 |
| Hauser, IA; Jakob, I; Lindemann, B; Thévenod, F | 1 |
| Müller, M; Roninson, I; Sarkadi, B; Szabó, K; Váradi, A; Welker, E | 1 |
| Bradham, CA; Brenner, DA; Cascio, WE; Crowe, RA; Elmore, SP; Herman, B; Lemasters, JJ; Nieminen, AL; Nishimura, Y; Qian, T; Trost, LC | 1 |
| Hauser, IA; Hopfer, U; Koziolek, M; Thévenod, F | 1 |
| Bowser, DN; Minamikawa, T; Nagley, P; Williams, DA | 1 |
| Bernardi, P; Canton, M; Colonna, R; Di Lisa, F; Miotto, G; Petronilli, V | 1 |
| Bernardi, P; Brini, M; Canton, M; Colonna, R; Di Lisa, F; Miotto, G; Petronilli, V | 1 |
| Wigler, PW | 1 |
| Beglinger, C; Drewe, J; Fricker, G; Gutmann, H; Michael, S; Török, M | 1 |
| Drewe, J; Fricker, G; Gutmann, H; Miller, DS; Toeroek, M | 1 |
| Legrand, O; Marie, JP; Perrot, JY; Simonin, G; Zittoun, R | 1 |
| Farber, JL; Hoek, JB; Marcineviciute, A; Marcinkeviciute, A; Pastorino, JG; Rothman, RJ; Tafani, M | 1 |
| Masereeuw, R; Miller, DS; Russel, FG; Terlouw, SA; van Aubel, RA | 1 |
| Chaloupka, R; Israël, N; Petit, PX; Sureau, F | 1 |
| Friedmann, JM; Hauser, IA; Katsen, AD; Thévenod, F | 1 |
| Leitch, GJ; Scanlon, M; Shaw, A; Visvesvara, GS | 1 |
| Hail, N; Lotan, R | 1 |
| Akaike, A; Honda, K; Inoue, R; Kihara, T; Nakamizo, T; Sawada, H; Shimohama, S; Urushitani, M | 1 |
| Albertioni, F; Eriksson, S; Löfgren, C; Månsson, E; Paul, A; Paul, C; Ullberg, K | 1 |
| Kamal, M; Mahida, YR; Ouellette, AJ; Podolsky, DK; Smith, A; Wakelin, D | 1 |
| Bernardi, P; Braidot, E; Gennaro, R; Macrì, F; Risso, A; Skerlavaj, B; Sordano, MC; Vianello, A; Zanetti, M | 1 |
| Hayashi, H; Katoh, H; Nishigaki, N | 1 |
| Albertioni, F; Eriksson, S; Lotfi, K; Månsson, E; Peterson, C | 1 |
| Coleman, R; Fernández-Moreno, MD; Fueyo, JA; Roma, MG; Román, ID | 1 |
| Dong, Y; Fechner, J; Feng, P; Hamawy, M; Hu, H; Knechtle, SJ | 1 |
| Litman, T; Skovsgaard, T; Stein, WD | 1 |
| Boersma, MG; Cnubben, NH; Rietjens, IM; Spenkelink, B; Usta, M; van Bladeren, PJ; van der Velde, AE; van Zanden, JJ; Wortelboer, HM | 1 |
| Bacsó, Z; Cianfriglia, M; Fenyvesi, F; Goda, K; Kappelmayer, J; Lustyik, G; Nagy, H; Szabó, G; Szilasi, M | 1 |
| Dogan, AL; Faussat, AM; Legrand, O; Marie, JP; Perrot, JY | 1 |
| Norenberg, MD; Rao, KV | 1 |
| Drinyaev, VA; Ermakova, NV; Korystov, YN; Kruglyak, EB; Kublik, LN; Levitman, MKh; Mosin, VA; Novik, TS; Shaposhnikova, VV; Sterlina, TS | 1 |
| Audus, KL; Jin, H | 1 |
| Capasso, G; Chiodini, P; Della Ragione, F; Di Gennaro, CI; Galletti, P; Indaco, S; Manna, C; Migliardi, V; Zappia, V | 1 |
| Buetler, TM; Krauskopf, A; Lhote, P; Petermann, O; Ruegg, UT | 1 |
| Garweg, JG; Goldblum, D; Wegmann-Burns, M | 1 |
| Bartlett, MC; Clarke, DM; Loo, TW | 1 |
| Akita, H; Hayashi, H; Hofmann, AF; Mita, S; Onuki, R; Sugiyama, Y; Suzuki, H | 1 |
| Bacsó, Z; Fenyvesi, F; Goda, K; Juhász, I; Krasznai, Z; Márián, T; Megyeri, A; Nagy, H; Szabó, G; Vecsernyés, M | 1 |
| Bakker, SJ; Gans, RO; Kauffman, HF; Koëter, GH; Slebos, DJ; van der Deen, M; van der Toorn, M | 1 |
| Chinn, LW; Gow, JM; Hodges, LM; Kroetz, DL | 1 |
| Beghin, D; Claude, N; Delongeas, JL; Farinotti, R; Forestier, F; Gil, S | 1 |
| Hayashi, H; Katoh, H; Saotome, M; Satoh, H; Tanaka, T; Urushida, T; Yaguchi, Y | 1 |
| DeFranco, DB; Devinney, MJ; Dineley, KE; Hastings, TG; Malaiyandi, LM; Vergun, O | 1 |
| Amioka, K; Haneda, M; Iwasaki, K; Kato, M; Kobayashi, T; Kurata, Y; Kuzuya, T; Miwa, Y; Nakao, A; Uchida, K; Watarai, Y | 1 |
| Abellán, A; Agulló, E; Garcia-Dorado, D; Miró-Casas, E; Ruiz-Meana, M | 1 |
| Hayashi, T; Ijiri, Y; Iwamoto, A; Kato, R; Kozu, C; Nishide, M; Suzuki, K; Tanaka, K; Urashima, K | 1 |
| Choi, JH; Hwang, IK; Lee, CH; Park, JH; Seong, JK; Shin, JH; Won, MH; Yi, SS; Yoo, KY; Yoon, YS | 1 |
| Cornelius, MG; Fricker, G; Huls, M; Ott, M | 1 |
| Currin, RT; Lemasters, JJ; Liu, Q; Ramshesh, VK; Rehman, H; Shi, Y; Sun, J; Zhong, Z | 1 |
| Abdallah, Y; Erdogan, A; Gündüz, D; Iraqi, W; Kasseckert, SA; Ladilov, Y; Neuhof, C; Piper, HM; Reusch, HP; Said, M; Schlüter, KD; Shahzad, T; Tillmanns, H | 1 |
| Fukuda, H; Fukuyama, Y; Nakanishi, T; Shibue, Y; Shirasaka, Y; Tamai, I; Yoshida, K | 1 |
| Alberici, LC; Curti, C; Dos Santos, GA; Pardo-Andreu, GL; Pestana, CR; Rodrigues, FP; Santos, AC; Uyemura, SA | 1 |
| Armstrong, C; Colombo, F; Duan, J; Rioux, N | 1 |
| Jakob, I; Molinas, A; Sicard, G | 1 |
| Bocci, E; Corsi, I; Della Torre, C; Focardi, SE | 1 |
| Achilli, TM; McCalla, S; Meyer, J; Morgan, JR; Tripathi, A | 1 |
| Boguen, R; Treulen, F; Uribe, P; Villegas, JV | 1 |
| Bua, J; Bustos, PL; Milduberger, N; Perrone, AE; Postan, M | 1 |
| Borlongan, CV; Kaneko, Y; Tajiri, N | 1 |
| Chen, R; Gan, X; Ren, Y; Xiao, A; You, C; Yu, H | 1 |
| Grimm, M; Javadov, S; Kuznetsov, AV; Margreiter, R; Saks, V | 1 |
| Abe, K; Ait-Oufella, H; Alacamli, G; Alacamli, OG; Amir, O; Antar, S; Ashour, H; Azimonti, G; Baba, Y; Balogun, MM; Bampidis, V; Bastos, ML; Ben Hamouda, N; Bickel Haase, T; Bjornsson, R; Bostan, M; Braik, R; Brantom, P; Briggs, S; Bujor, I; Canbek, TD; Cherecheanu, AP; Chesson, A; Choudhary, RJ; Christensen, H; Chung, HR; Clavier, T; Dahman, NBH; Dani, S; Demailly, Z; Devine, LD; Ding, G; Duan, X; Durjava, M; Dusemund, B; Edebali, S; Elbaz Greener, G; Elnoby, AS; Fang, Q; Fares, AM; Fashola, MB; Fawzy, MS; Fouad, FM; Fu, SZ; Fujita, S; Furusawa, S; Gallagher, AM; Gao, J; Goyal, N; Guo, J; Hamuda, N; Han, Y; Hariri, G; Heist, EK; Hill, AJ; Homoud, M; Hu, Q; Hu, Z; Huang, L; Ide, T; Ikeda, M; Ishimaru, K; Jiang, C; Kaderli, ST; Kanamura, T; Karalezli, A; Kaur, P; Kazatsker, M; Kobo, O; Kouba, M; Kumar, R; Lavillegrand, JR; Leshem, E; Li, A; Li, S; Liu, R; López Puente, S; López-Alonso, M; Ma, M; Madias, C; Manini, P; Marcon, F; Margolis, G; Matsushima, S; Mayo, B; Miller, JE; Miyake, R; Miyamoto, HD; Naumann-Gola, S; Ortner, E; Pandit, R; Pang, Y; Pechová, A; Petkova, M; Pîrvulescu, R; Popa-Cherecheanu, A; Ramos, F; Roguin, A; Rozen, G; Ruskin, JN; Sanz, Y; Schweiggert-Weisz, U; Shafie, AAA; Sharma, H; Shi, X; Stoicescu, EA; Stopyra, W; Suh, JD; Sul, S; Tamion, F; Tiu, C; Tohyama, T; Tsutsui, H; Tsutsui, Y; Vandestienne, M; Villa, RE; Wang, P; Watanabe, M; Westendorf, J; Woutersen, R; Xia, J; Xing, W; Xu, X; Yang, L; Yang, N; Yu, J; Yu, M; Yu, X; Zhang, L; Zhao, Y; Zhao, Z; Zhou, X; Zorn, H | 1 |
3 review(s) available for erythrosine and cyclosporine
| Article | Year |
|---|---|
The mitochondrial permeability transition in cell death: a common mechanism in necrosis, apoptosis and autophagy.
Topics: Animals; Apoptosis; Autophagy; Calcimycin; Calcium; Cells, Cultured; Cyclosporine; Fluoresceins; Hydrogen-Ion Concentration; Microscopy, Confocal; Mitochondria; Mitochondria, Liver; Necrosis; Oxidative Stress; Permeability; Peroxides; Reactive Oxygen Species; Rhodamines; Superoxides; tert-Butylhydroperoxide | 1998 |
Imaging the mitochondrial permeability transition pore in intact cells.
Topics: Animals; Cell Membrane Permeability; Cobalt; Cyclosporine; Fluoresceins; Fluorescent Dyes; Humans; Microscopy, Confocal; Mitochondria | 1998 |
Topics: Adolescent; Adult; Animals; Asthma; Atrial Fibrillation; Autoantibodies; Biomarkers; Breast Neoplasms; Child; Conjunctivitis, Allergic; Cornea; COVID-19; Cyclosporine; Cytokines; Death, Sudden, Cardiac; Defibrillators, Implantable; Diet; Disease Models, Animal; Docetaxel; Double-Blind Method; Dry Eye Syndromes; Educational Status; Emulsions; Female; Fluorescein Angiography; Fluoresceins; Focus Groups; Heart Failure; Hemothorax; Humans; Inflammation; Keratoconus; Male; Meibomian Glands; Mice; Middle Aged; Multiple Sclerosis; Myocardial Infarction; Myocardium; Nerve Fibers; Nigeria; Obesity; Overweight; Pandemics; Primary Prevention; Prospective Studies; Qualitative Research; Registries; Retinal Ganglion Cells; Retinal Vessels; Schools; Sirolimus; Tertiary Care Centers; Th1 Cells; Th2 Cells; Tomography, Optical Coherence; Troponin I; Tumor Necrosis Factor-alpha; United States; Ventricular Remodeling | 2022 |
2 trial(s) available for erythrosine and cyclosporine
| Article | Year |
|---|---|
Pretransplant pharmacodynamic analysis of immunosuppressive agents using CFSE-based T-cell proliferation assay.
Topics: Adult; Cell Proliferation; Cyclosporine; Female; Fluoresceins; Fluorescent Dyes; Humans; Immunosuppressive Agents; Kidney Failure, Chronic; Kidney Transplantation; Male; Middle Aged; Prednisolone; Prospective Studies; Succinimides; T-Lymphocytes; Tacrolimus | 2009 |
Topics: Adolescent; Adult; Animals; Asthma; Atrial Fibrillation; Autoantibodies; Biomarkers; Breast Neoplasms; Child; Conjunctivitis, Allergic; Cornea; COVID-19; Cyclosporine; Cytokines; Death, Sudden, Cardiac; Defibrillators, Implantable; Diet; Disease Models, Animal; Docetaxel; Double-Blind Method; Dry Eye Syndromes; Educational Status; Emulsions; Female; Fluorescein Angiography; Fluoresceins; Focus Groups; Heart Failure; Hemothorax; Humans; Inflammation; Keratoconus; Male; Meibomian Glands; Mice; Middle Aged; Multiple Sclerosis; Myocardial Infarction; Myocardium; Nerve Fibers; Nigeria; Obesity; Overweight; Pandemics; Primary Prevention; Prospective Studies; Qualitative Research; Registries; Retinal Ganglion Cells; Retinal Vessels; Schools; Sirolimus; Tertiary Care Centers; Th1 Cells; Th2 Cells; Tomography, Optical Coherence; Troponin I; Tumor Necrosis Factor-alpha; United States; Ventricular Remodeling | 2022 |
71 other study(ies) available for erythrosine and cyclosporine
| Article | Year |
|---|---|
Inhibition of the multidrug efflux pump in isolated hepatocyte couplets by immunosuppressants FK506 and cyclosporine.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Bile Canaliculi; Cyclosporine; Daunorubicin; Drug Resistance; Fluoresceins; Fluorescent Dyes; Fura-2; Liver; Membrane Glycoproteins; Microscopy, Fluorescence; Progesterone; Rats; Signal Processing, Computer-Assisted; Tacrolimus; Verapamil; Vinblastine | 1993 |
Modulation of the mitochondrial cyclosporin A-sensitive permeability transition pore by matrix pH. Evidence that the pore open-closed probability is regulated by reversible histidine protonation.
Topics: Animals; Calcium; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Cyclosporine; Diethyl Pyrocarbonate; Fluoresceins; Fluorescent Dyes; Histidine; Hydrogen-Ion Concentration; Hydroxylamine; Hydroxylamines; Ion Channel Gating; Ion Channels; Kinetics; Mitochondria, Liver; Rats | 1993 |
Disruption of canalicular function in isolated rat hepatocyte couplets caused by cyclosporin A.
Topics: Actins; Animals; Bile Canaliculi; Cholic Acids; Cyclosporine; Dose-Response Relationship, Drug; Fluoresceins; Fluorescent Dyes; Glutathione; Liver; Male; Rats; Rats, Wistar | 1994 |
Constitutive expression of P-glycoprotein as a determinant of loading with fluorescent calcium probes.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Calcium; CHO Cells; Cricetinae; Cricetulus; Cyclosporine; Cytosol; Female; Flow Cytometry; Fluoresceins; Fluorescent Dyes; Humans; Indoles; Rhodamine 123; Rhodamines; Verapamil | 1994 |
Microfluorometric evaluation of calcein acetoxymethyl ester as a probe for P-glycoprotein-mediated resistance: effects of cyclosporin A and its nonimmunosuppressive analogue SDZ PSC 833.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Carrier Proteins; Cyanides; Cyclosporine; Cyclosporins; Drug Resistance; Fluoresceins; Membrane Glycoproteins; Rats; Tumor Cells, Cultured; Vincristine | 1994 |
Influence of topically applied cyclosporine A in olive oil on corneal epithelium permeability.
Topics: Administration, Topical; Adult; Cell Membrane Permeability; Cornea; Corneal Diseases; Cyclosporine; Emulsions; Female; Fluorescein; Fluoresceins; Fluorophotometry; Humans; Male; Olive Oil; Ophthalmic Solutions; Plant Oils; Pruritus | 1994 |
An in vitro model of cyclosporine-induced nephrotoxicity.
Topics: Alkaline Phosphatase; Animals; Cell Survival; Cells, Cultured; Cyclosporine; Fluoresceins; Fluorescent Dyes; Kidney Cortex; Kidney Diseases; L-Lactate Dehydrogenase; Mitochondria; Neutral Red; Pharmaceutical Vehicles; Polyethylene Glycols; Propidium; Rats; Rats, Sprague-Dawley; Tetrazolium Salts; Thiazoles | 1993 |
Production of interference in the TDx polarization immunoassay by fluorescein angiography.
Topics: Angiography; Cyclosporine; Drug Monitoring; Fluorescein; Fluoresceins; Fluorescence; Fluorescence Polarization Immunoassay; Injections, Intravenous | 1993 |
S-adenosyl-L-methionine prevents disruption of canalicular function and pericanalicular cytoskeleton integrity caused by cyclosporin A in isolated rat hepatocyte couplets.
Topics: Actins; Animals; Bile Canaliculi; Cells, Cultured; Cholic Acids; Cyclosporine; Cytoskeleton; Fluoresceins; Fluorescent Dyes; Glutathione; Immunosuppressive Agents; Liver; Male; Phalloidine; Rats; Rats, Wistar; S-Adenosylmethionine; Vacuoles | 1996 |
Influence of topical cyclosporine A and dissolvent on corneal epithelium permeability of fluorescein.
Topics: Administration, Topical; Adolescent; Adult; Cell Membrane Permeability; Cornea; Cyclosporine; Epithelium; Female; Fluorescein; Fluoresceins; Fluorophotometry; Humans; Immunosuppressive Agents; Male; Oils; Ophthalmic Solutions; Pharmaceutical Vehicles; Reference Values | 1995 |
Chemosensitization and drug accumulation effects of VX-710, verapamil, cyclosporin A, MS-209 and GF120918 in multidrug resistant HL60/ADR cells expressing the multidrug resistance-associated protein MRP.
Topics: Acridines; Affinity Labels; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Cyclosporine; Daunorubicin; Doxorubicin; Drug Resistance, Multiple; Etoposide; Fluoresceins; HL-60 Cells; Humans; Isoquinolines; Multidrug Resistance-Associated Proteins; Piperidines; Pyridines; Quinolines; Tetrahydroisoquinolines; Tritium; Verapamil; Vincristine | 1997 |
Cytotoxic activity of calcein acetoxymethyl ester (Calcein/AM) on primary cultures of human haematological and solid tumours.
Topics: Antineoplastic Agents; Cell Survival; Cyclosporine; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Drug Synergism; Fluoresceins; Humans; Leukemia; Tumor Cells, Cultured | 1996 |
Distribution of cyclophilin B-binding sites in the subsets of human peripheral blood lymphocytes.
Topics: Amino Acid Isomerases; Binding Sites; Binding, Competitive; Carrier Proteins; CD4-Positive T-Lymphocytes; Cell Culture Techniques; Cyclophilins; Cyclosporine; Fluoresceins; Humans; Immunophenotyping; Immunosuppressive Agents; Lymphocyte Activation; Peptidylprolyl Isomerase; Recombinant Proteins; T-Lymphocyte Subsets | 1997 |
MDR1 in taste buds of rat vallate papilla: functional, immunohistochemical, and biochemical evidence.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Connective Tissue Cells; Cyclosporine; Epithelial Cells; Female; Fluoresceins; Fluorescent Dyes; Immunoglobulin G; In Vitro Techniques; Kinetics; Male; Microscopy, Fluorescence; Rats; Rats, Sprague-Dawley; Tamoxifen; Taste Buds; Tongue; Verapamil | 1998 |
Drug-stimulated nucleotide trapping in the human multidrug transporter MDR1. Cooperation of the nucleotide binding domains.
Topics: Adenine Nucleotides; Adenosine Triphosphatases; ATP Binding Cassette Transporter, Subfamily B, Member 1; Binding Sites; Cyclosporine; Enzyme Inhibitors; Ethylmaleimide; Fluoresceins; Fluorouracil; Humans; Protein Binding; Recombinant Proteins; Verapamil | 1998 |
Therapeutic concentrations of cyclosporine A, but not FK506, increase P-glycoprotein expression in endothelial and renal tubule cells.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport, Active; Cell Line; Cyclosporine; Endothelium, Vascular; Fluoresceins; Fluorescent Dyes; Humans; Immunohistochemistry; Kidney Tubules; Kinetics; Rats; Tacrolimus; Verapamil | 1998 |
Mitochondrial permeability transition and swelling can occur reversibly without inducing cell death in intact human cells.
Topics: Aldehydes; Apoptosis; Benzimidazoles; Carbocyanines; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cell Survival; Cyclosporine; Fluoresceins; Fluorescent Dyes; Humans; Intracellular Membranes; Ionophores; Membrane Potentials; Microscopy, Confocal; Mitochondria; Mitochondrial Swelling; Organic Chemicals; Osteosarcoma; Permeability; Staining and Labeling; Tumor Cells, Cultured | 1999 |
Transient and long-lasting openings of the mitochondrial permeability transition pore can be monitored directly in intact cells by changes in mitochondrial calcein fluorescence.
Topics: Animals; Calcium; Caseins; Cell Membrane Permeability; Cells, Cultured; Cobalt; Cyclosporine; Fluoresceins; Fluorescent Dyes; Microscopy, Fluorescence; Mitochondria, Liver; Rats; Rhodamines; Spectrometry, Fluorescence | 1999 |
PSC833, cyclosporin A, and dexniguldipine effects on cellular calcein retention and inhibition of the multidrug resistance pump in human leukemic lymphoblasts.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Cyclosporine; Cyclosporins; Dihydropyridines; Drug Resistance, Neoplasm; Fluoresceins; Half-Life; Humans; Inhibitory Concentration 50; Kinetics; Leukemia; Lymphocytes; Molecular Weight; Tumor Cells, Cultured | 1999 |
Evidence for different ABC-transporters in Caco-2 cells modulating drug uptake.
Topics: ATP Binding Cassette Transporter, Subfamily B; ATP-Binding Cassette Transporters; Blotting, Western; Caco-2 Cells; Cyclosporine; Fluoresceins; Humans; Intestinal Absorption; Molecular Sequence Data; Multidrug Resistance-Associated Proteins; Propionates; Quinolines; Reverse Transcriptase Polymerase Chain Reaction | 1999 |
Interactions of HIV protease inhibitors with ATP-dependent drug export proteins.
Topics: Adenosine Triphosphatases; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Cyclosporine; Fluoresceins; HIV Protease Inhibitors; Killifishes; Methotrexate; Mitochondrial Proteins; Ribosomal Proteins; Ritonavir; Saccharomyces cerevisiae Proteins; Saquinavir | 1999 |
Both Pgp and MRP1 activities using calcein-AM contribute to drug resistance in AML.
Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Base Pair Mismatch; Biological Transport; Calcium; Cyclosporine; DNA-Binding Proteins; Drug Resistance, Multiple; Female; Flow Cytometry; Fluoresceins; Fluorescent Dyes; Genes, MDR; Humans; K562 Cells; Leukemia, Myeloid, Acute; Male; Multidrug Resistance-Associated Proteins; MutS Homolog 3 Protein; RNA, Messenger; Transcription, Genetic; Tumor Cells, Cultured | 1999 |
Functional consequences of the sustained or transient activation by Bax of the mitochondrial permeability transition pore.
Topics: Adenylate Kinase; Animals; Apoptosis; Atractyloside; bcl-2-Associated X Protein; Calcium; Ceramides; Cyclosporine; Cytochrome c Group; Fluoresceins; Gangliosides; Intracellular Membranes; Ion Channels; Membrane Potentials; Membrane Proteins; Mitochondria, Liver; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Permeability; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Rats | 1999 |
Endothelin B receptor-mediated regulation of ATP-driven drug secretion in renal proximal tubule.
Topics: Adenosine Triphosphate; Animals; Anion Transport Proteins; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Carrier Proteins; Cyclosporine; Endothelins; Fluoresceins; Iohexol; Kidney Tubules, Proximal; Killifishes; Methotrexate; Protein Kinase C; Receptor, Endothelin B; Receptors, Endothelin | 2000 |
Over-expression of Bcl-2 does not protect cells from hypericin photo-induced mitochondrial membrane depolarization, but delays subsequent events in the apoptotic pathway.
Topics: 3T3 Cells; Animals; Anthracenes; Apoptosis; Bongkrekic Acid; Caspase 3; Caspases; Cell Line; Cell Membrane Permeability; Cyclosporine; Dose-Response Relationship, Radiation; Enzyme Activation; Fibroblasts; Flow Cytometry; Fluoresceins; Humans; Hydrogen-Ion Concentration; Intracellular Membranes; Membrane Potentials; Mice; Microscopy, Confocal; Mitochondria; Perylene; Phosphatidylserines; Photosensitivity Disorders; Proto-Oncogene Proteins c-bcl-2; Time Factors | 1999 |
Up-regulation of multidrug resistance P-glycoprotein via nuclear factor-kappaB activation protects kidney proximal tubule cells from cadmium- and reactive oxygen species-induced apoptosis.
Topics: Animals; Annexin A5; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cadmium; Cadmium Chloride; Calcium Channel Blockers; Cell Line; Cyclosporine; Cyclosporins; Enzyme Inhibitors; Fluoresceins; Kidney Tubules, Proximal; Kinetics; Necrosis; NF-kappa B; Oxidative Stress; Rats; Rats, Inbred WKY; Reactive Oxygen Species; Time Factors; Up-Regulation; Verapamil | 2000 |
Role of P glycoprotein in the course and treatment of Encephalitozoon microsporidiosis.
Topics: Acquired Immunodeficiency Syndrome; Albendazole; Animals; Anthelmintics; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Calcium Channel Blockers; Cells, Cultured; Chlorocebus aethiops; Cyclosporine; Encephalitozoon; Encephalitozoonosis; Fluoresceins; Genes, MDR; Immunohistochemistry; Immunosuppressive Agents; Verapamil | 2001 |
Mitochondrial permeability transition is a central coordinating event in N-(4-hydroxyphenyl)retinamide-induced apoptosis.
Topics: Anticarcinogenic Agents; Apoptosis; Ascorbic Acid; Carcinoma, Squamous Cell; Cell Division; Cyclosporine; DNA Fragmentation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Fenretinide; Fluoresceins; Fluorescent Dyes; Humans; Intracellular Membranes; Membrane Potentials; Mitochondria; Oxidation-Reduction; Permeability; Reactive Oxygen Species; Rhodamine 123; Skin Neoplasms; Tumor Cells, Cultured | 2000 |
N-methyl-D-aspartate receptor-mediated mitochondrial Ca(2+) overload in acute excitotoxic motor neuron death: a mechanism distinct from chronic neurotoxicity after Ca(2+) influx.
Topics: 2,4-Dinitrophenol; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Calcium Signaling; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Cells, Cultured; Cyclosporine; Dibucaine; Dizocilpine Maleate; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Fluoresceins; Fluorescent Dyes; Glutamic Acid; Heterocyclic Compounds, 3-Ring; Imidazoles; Kainic Acid; Mitochondria; Motor Neuron Disease; Motor Neurons; N-Methylaspartate; Nerve Tissue Proteins; Neurons; Neurotoxins; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Oxidative Stress; Rats; Rats, Wistar; Reactive Oxygen Species; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Rhodamines; Spinal Cord; Superoxide Dismutase; Uncoupling Agents | 2001 |
Cross-resistance to cytosine arabinoside in a multidrug-resistant human promyelocytic cell line selected for resistance to doxorubicin: implications for combination chemotherapy.
Topics: Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cyclosporine; Cyclosporins; Cytarabine; Deoxycytidine Kinase; DNA Fragmentation; Doxorubicin; Drug Resistance, Multiple; Flow Cytometry; Fluoresceins; HL-60 Cells; Humans; Leukemia, Promyelocytic, Acute | 2001 |
Mucosal T cells regulate Paneth and intermediate cell numbers in the small intestine of T. spiralis-infected mice.
Topics: Animals; Cell Division; Coloring Agents; Cyclosporine; Female; Fluoresceins; Genes, T-Cell Receptor; Growth Substances; Immunity, Mucosal; Intestinal Mucosa; Intestine, Small; Lymph Nodes; Mice; Mice, Inbred BALB C; Mice, Knockout; Mice, Nude; Mucins; Muscle Proteins; Neuropeptides; Paneth Cells; Peptides; Protein Precursors; T-Lymphocytes; Tartrazine; Trefoil Factor-2; Trefoil Factor-3; Trichinellosis | 2001 |
BMAP-28, an antibiotic peptide of innate immunity, induces cell death through opening of the mitochondrial permeability transition pore.
Topics: Animals; Anti-Infective Agents; Antimicrobial Cationic Peptides; Calcium; Cattle; Cell Death; Cells, Cultured; Cyclosporine; Cytochrome c Group; Dose-Response Relationship, Drug; Fluoresceins; Fluorescent Dyes; Humans; Immunity, Innate; Ion Channels; K562 Cells; Leukocytes, Mononuclear; Membrane Potentials; Membrane Proteins; Mitochondria; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Proteins; U937 Cells | 2002 |
Diazoxide opens the mitochondrial permeability transition pore and alters Ca2+ transients in rat ventricular myocytes.
Topics: Animals; Antihypertensive Agents; Calcium; Calcium Signaling; Cyclosporine; Diazoxide; Enzyme Inhibitors; Flavoproteins; Fluoresceins; Fluorescent Dyes; Heart Ventricles; In Vitro Techniques; Intracellular Membranes; Ion Channels; Membrane Potentials; Microscopy, Confocal; Mitochondria; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Myocardium; Oxidation-Reduction; Rats | 2002 |
Low level of mitochondrial deoxyguanosine kinase is the dominant factor in acquired resistance to 9-beta-D-arabinofuranosylguanine cytotoxicity.
Topics: Anthracyclines; Antineoplastic Agents; Arabinonucleosides; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blotting, Western; Cells, Cultured; Cyclosporine; Daunorubicin; Deoxycytidine Kinase; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Electrophoresis, Polyacrylamide Gel; Flow Cytometry; Fluoresceins; Humans; Mitochondria; Nucleosides; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured | 2002 |
Cyclosporin A induced internalization of the bile salt export pump in isolated rat hepatocyte couplets.
Topics: Animals; ATP-Binding Cassette Transporters; Bile Acids and Salts; Bile Canaliculi; Biological Transport, Active; Cells, Cultured; Cholic Acids; Cyclosporine; Dose-Response Relationship, Drug; Fluoresceins; Hepatocytes; Immunosuppressive Agents; Male; Rats; Rats, Wistar; Tacrolimus | 2003 |
Effect of immunosuppressants on T-cell subsets observed in vivo using carboxy-fluorescein diacetate succinimidyl ester labeling.
Topics: Animals; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cell Division; Cyclosporine; Fluoresceins; Fluorescent Dyes; Immunosuppressive Agents; Lymphocyte Culture Test, Mixed; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, SCID; Sirolimus; Succinimides; Tacrolimus | 2003 |
Pumping of drugs by P-glycoprotein: a two-step process?
Topics: Algorithms; Animals; Anti-Bacterial Agents; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blotting, Western; Calcium Channel Blockers; Carcinoma, Ehrlich Tumor; Cell Line, Tumor; Cyclosporine; Daunorubicin; Fluoresceins; Humans; Immunosuppressive Agents; Kinetics; Models, Biological; Pharmaceutical Preparations; Quinolines; Verapamil; Vinblastine | 2003 |
Interplay between MRP inhibition and metabolism of MRP inhibitors: the case of curcumin.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Baculoviridae; Cell Line; Curcumin; Cyclosporine; Dinitrochlorobenzene; Dose-Response Relationship, Drug; Drug Resistance, Multiple; Ethacrynic Acid; Fluoresceins; Glutathione; Glutathione Transferase; Humans; Propionates; Quinolines; Recombinant Proteins; Spodoptera | 2003 |
Distinct groups of multidrug resistance modulating agents are distinguished by competition of P-glycoprotein-specific antibodies.
Topics: Adenosine Triphosphatases; Animals; Anti-Bacterial Agents; Antibodies, Monoclonal; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Binding, Competitive; Calcium Channel Blockers; Cyclosporine; Detergents; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Flow Cytometry; Fluoresceins; Humans; Ivermectin; Mice; NIH 3T3 Cells; Substrate Specificity | 2004 |
Evaluation and comparison of MRP1 activity with three fluorescent dyes and three modulators in leukemic cell lines.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Bronchodilator Agents; Cyclosporine; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Enzyme Inhibitors; Fluoresceins; Fluorescent Dyes; Humans; Leukemia; Multidrug Resistance-Associated Proteins; Probenecid; Propionates; Quinolines; Rhodamine 123; Tumor Cells, Cultured | 2004 |
Manganese induces the mitochondrial permeability transition in cultured astrocytes.
Topics: Animals; Antioxidants; Astrocytes; Cell Membrane Permeability; Cells, Cultured; Cyclosporine; Fluoresceins; Immunosuppressive Agents; Intracellular Membranes; Manganese; Membrane Potentials; Microscopy, Fluorescence; Mitochondria; Neurons; Oxidative Stress; Permeability; Rats; Time Factors | 2004 |
Avermectins inhibit multidrug resistance of tumor cells.
Topics: Animals; Cell Division; Cell Line, Tumor; Cell Survival; Cyclosporine; Dose-Response Relationship, Drug; Drug Combinations; Drug Evaluation, Preclinical; Drug Resistance, Multiple; Drug Synergism; Fluoresceins; Fluorescence; Humans; Ivermectin; Leukemia P388; Male; Mice; Paclitaxel; Rhodamine 123; Russia; Vincristine | 2004 |
Effect of bisphenol A on drug efflux in BeWo, a human trophoblast-like cell line.
Topics: Adenosine Triphosphatases; ATP Binding Cassette Transporter, Subfamily B, Member 1; Benzhydryl Compounds; Biological Transport, Active; Cell Line; Cyclosporine; Esterases; Estradiol; Estrogens, Non-Steroidal; Female; Fluoresceins; Fluorescent Dyes; Humans; Phenols; Pregnancy; Trophoblasts | 2005 |
Diverse effects of natural antioxidants on cyclosporin cytotoxicity in rat renal tubular cells.
Topics: Animals; Antioxidants; Cell Survival; Cells, Cultured; Cyclosporine; Epithelium; Fluoresceins; Glutathione; Kidney Diseases; Kidney Tubules, Proximal; Lipid Peroxides; Phenylethyl Alcohol; Rats; Rats, Inbred WKY; Reactive Oxygen Species; Resveratrol; Stilbenes; Thiobarbituric Acid Reactive Substances; Vitamin E | 2005 |
Cyclosporin A generates superoxide in smooth muscle cells.
Topics: Animals; Aorta; Cells, Cultured; Cyclosporine; Dose-Response Relationship, Drug; Ethidium; Fluoresceins; Free Radical Scavengers; Immunosuppressive Agents; Male; Myocytes, Smooth Muscle; Rats; Reactive Oxygen Species; Superoxide Dismutase; Superoxides | 2005 |
Effects of daunorubicin, mitomycin C, azathioprine and cyclosporin A on human retinal pigmented epithelial, corneal endothelial and conjunctival cell lines.
Topics: Antimetabolites; Azathioprine; Cell Count; Cell Line; Cell Proliferation; Conjunctiva; Cyclosporine; Daunorubicin; Endothelium, Corneal; Epithelial Cells; Fluoresceins; Humans; Immunosuppressive Agents; Mitomycin; Pigment Epithelium of Eye; Propidium | 2006 |
Transmembrane segment 1 of human P-glycoprotein contributes to the drug-binding pocket.
Topics: Adenosine Triphosphatases; Amino Acid Sequence; Amino Acid Substitution; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Binding Sites; Cell Line; Colchicine; Cricetinae; Cyclosporine; Demecolcine; Disulfides; Dithiothreitol; Fluoresceins; Flupenthixol; Humans; Mesylates; Point Mutation; Protein Structure, Tertiary; Verapamil; Vinblastine | 2006 |
Inhibition of bile acid transport across Na+/taurocholate cotransporting polypeptide (SLC10A1) and bile salt export pump (ABCB 11)-coexpressing LLC-PK1 cells by cholestasis-inducing drugs.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Biological Transport; Cholestasis; Cyclosporine; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Fluoresceins; Kinetics; LLC-PK1 Cells; Organic Anion Transporters, Sodium-Dependent; Oxadiazoles; Rifampin; Rifamycins; Swine; Symporters; Taurocholic Acid; Transfection | 2006 |
Complete inhibition of P-glycoprotein by simultaneous treatment with a distinct class of modulators and the UIC2 monoclonal antibody.
Topics: Animals; Antibodies, Monoclonal; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cyclosporine; Cyclosporins; Daunorubicin; Fluoresceins; Humans; Mice; NIH 3T3 Cells; Vinblastine | 2007 |
Cyclosporin A-induced oxidative stress is not the consequence of an increase in mitochondrial membrane potential.
Topics: Aniline Compounds; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Benzimidazoles; Calcium; Carbocyanines; Cell Line; Cyclosporine; Cytoplasm; Fluoresceins; Fluorescent Dyes; Humans; Immunosuppressive Agents; In Vitro Techniques; Membrane Potential, Mitochondrial; Mitochondria, Liver; Mitochondrial Membrane Transport Proteins; Mitochondrial Membranes; Mitochondrial Permeability Transition Pore; Oxidative Stress; Reactive Oxygen Species; Swine; Xanthenes | 2007 |
Substrate-dependent effects of human ABCB1 coding polymorphisms.
Topics: ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Boron Compounds; Cell Line; Cyclosporine; Fluoresceins; Gene Frequency; Haplotypes; Humans; Paclitaxel; Polymorphism, Genetic | 2008 |
Development and characterisation of a new model of rat trophoblasts.
Topics: Animal Testing Alternatives; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Cell Proliferation; Cell Survival; Cryopreservation; Cyclosporine; Cyclosporins; Drug Evaluation, Preclinical; Female; Fluoresceins; Fluorescent Dyes; Neoplasm Proteins; Organ Culture Techniques; Pregnancy; Rats; Rats, Wistar; Rhodamine 123; Trophoblasts | 2009 |
Transient opening of mitochondrial permeability transition pore by reactive oxygen species protects myocardium from ischemia-reperfusion injury.
Topics: Animals; Calcium; Cyclosporine; Fluoresceins; Hydrogen Peroxide; Magnetic Resonance Spectroscopy; Male; Membrane Potential, Mitochondrial; Mitochondria, Heart; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Myocardial Contraction; Myocardium; Myocytes, Cardiac; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Reperfusion Injury; Ventricular Function, Left | 2009 |
A comparison of Zn2+- and Ca2+-triggered depolarization of liver mitochondria reveals no evidence of Zn2+-induced permeability transition.
Topics: Animals; Calcium; Cation Transport Proteins; Cyclosporine; Enzyme Inhibitors; Fluoresceins; Fluorescent Dyes; Membrane Potential, Mitochondrial; Mitochondria, Liver; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Permeability; Rats; Rats, Sprague-Dawley; Rhodamine 123; Ruthenium Red; Zinc | 2009 |
Role of sarcoplasmic reticulum in mitochondrial permeability transition and cardiomyocyte death during reperfusion.
Topics: Animals; Calcium Signaling; Cell Death; Cells, Cultured; Colchicine; Cyclosporine; Enzyme Inhibitors; Fluoresceins; Ischemic Contracture; Male; Membrane Potential, Mitochondrial; Microtubules; Mitochondria, Heart; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Myocardial Reperfusion Injury; Myocytes, Cardiac; Rats; Rats, Sprague-Dawley; Ryanodine; Sarcoplasmic Reticulum; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Thapsigargin; Time Factors; Tubulin Modulators | 2009 |
Is cyclosporine A transport inhibited by pravastatin via multidrug resistant protein 2?
Topics: Biological Transport; Caco-2 Cells; Cell Survival; Cyclosporine; Drug Interactions; Female; Fluoresceins; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Immunosuppressive Agents; Middle Aged; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Polymyositis; Pravastatin | 2010 |
Cyclosporine A reduces dendritic outgrowth of neuroblasts in the subgranular zone of the dentate gyrus in C57BL/6 mice.
Topics: Animals; Astrocytes; Blotting, Western; Calcium-Binding Proteins; Cell Proliferation; Cyclosporine; Cytoplasmic Granules; Dendrites; Dentate Gyrus; DNA-Binding Proteins; Doublecortin Domain Proteins; Doublecortin Protein; Fluoresceins; Fluorescent Dyes; Glial Fibrillary Acidic Protein; Immunohistochemistry; Immunosuppressive Agents; Ki-67 Antigen; Male; Mice; Mice, Inbred C57BL; Microfilament Proteins; Microglia; Microtubule-Associated Proteins; Nerve Tissue Proteins; Neurogenesis; Neurons; Neuropeptides; Nuclear Proteins; Organic Chemicals | 2010 |
St. John's Wort constituents modulate P-glycoprotein transport activity at the blood-brain barrier.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport, Active; Blood-Brain Barrier; Blotting, Western; Capillaries; Cells, Cultured; Cyclosporine; Endothelial Cells; Fluoresceins; Fluorescent Dyes; Hypericum; Immunohistochemistry; In Vitro Techniques; Protein Kinase C; Quercetin; Signal Transduction; Swine | 2010 |
NIM811 prevents mitochondrial dysfunction, attenuates liver injury, and stimulates liver regeneration after massive hepatectomy.
Topics: Adenosine Triphosphate; Alanine Transaminase; Animals; Caspase 3; Cell Death; Cyclosporine; Cytochromes c; Fluoresceins; Hepatectomy; Liver; Liver Regeneration; Male; Membrane Potential, Mitochondrial; Mice; Mice, Inbred C57BL; Mitochondrial Diseases; Organ Size; Proliferating Cell Nuclear Antigen | 2011 |
Interplay between Ca2+ cycling and mitochondrial permeability transition pores promotes reperfusion-induced injury of cardiac myocytes.
Topics: Acetylcysteine; Adenosine Triphosphate; Animals; Calcium; Cyclosporine; Fluoresceins; Male; Membrane Potential, Mitochondrial; Mitochondria, Heart; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Myocardial Reperfusion Injury; Myocytes, Cardiac; Necrosis; Rats; Rats, Wistar; Reactive Oxygen Species; Ruthenium Compounds; Ryanodine; Thapsigargin; Tiopronin | 2011 |
Quantitative time-lapse imaging-based analysis of drug-drug interaction mediated by hepatobiliary transporter, multidrug resistance-associated protein 2, in sandwich-cultured rat hepatocytes.
Topics: Animals; ATP-Binding Cassette Transporters; Bile Canaliculi; Cell Culture Techniques; Cell Membrane; Cells, Cultured; Cyclosporine; Drug Interactions; Fluoresceins; Fluorescent Dyes; Hepatocytes; Hyperbilirubinemia; Male; Microscopy, Fluorescence; Molecular Imaging; Pharmaceutical Preparations; Propionates; Quinolines; Rats; Rats, Sprague-Dawley; Rats, Wistar; Rifampin | 2011 |
Characterization of the stimulus for reactive oxygen species generation in calcium-overloaded mitochondria.
Topics: Analysis of Variance; Animals; Calcium; Cyclosporine; Electron Transport; Electron Transport Complex I; Electron Transport Complex III; Fluoresceins; Fluorescent Dyes; Glutamic Acid; Hydrogen Peroxide; Male; Membrane Potential, Mitochondrial; Mitochondria, Liver; Mitochondrial Membranes; Oxazines; Rats; Rats, Wistar; Reactive Oxygen Species; Rotenone; Succinic Acid | 2011 |
A high throughput in vitro mrp2 assay to predict in vivo biliary excretion.
Topics: Animals; ATP-Binding Cassette Transporters; Benzbromarone; Bile Canaliculi; Biliary Tract; Biological Transport; Cyclosporine; Digoxin; Drug Evaluation, Preclinical; Drug Interactions; Fluoresceins; High-Throughput Screening Assays; Metabolic Clearance Rate; Propionates; Quinolines; Rats; Taurocholic Acid; Transport Vesicles | 2012 |
Functional evidence of multidrug resistance transporters (MDR) in rodent olfactory epithelium.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP-Binding Cassette Sub-Family B Member 4; Biological Transport; Cyclosporine; Female; Fluoresceins; Gene Expression; Male; Mice; Mice, Inbred BALB C; Microscopy, Fluorescence; Multidrug Resistance-Associated Proteins; Olfactory Mucosa; Olfactory Receptor Neurons; Probenecid; Propionates; Quinolines; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; Verapamil | 2012 |
Differential ABCB and ABCC gene expression and efflux activities in gills and hemocytes of Mytilus galloprovincialis and their involvement in cadmium response.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cadmium; Cyclosporine; Fluoresceins; Fluorescent Dyes; Gene Expression Regulation; Gills; Hemocytes; Multidrug Resistance-Associated Proteins; Mytilus; Propionates; Quinolines; Water Pollutants, Chemical | 2014 |
Multilayer spheroids to quantify drug uptake and diffusion in 3D.
Topics: ATP Binding Cassette Transporter, Subfamily B; Carbenoxolone; Cell Line; Cell Line, Tumor; Cyclosporine; Diffusion; Fluoresceins; HEK293 Cells; Humans; Loperamide; MCF-7 Cells; Pharmaceutical Preparations; Spheroids, Cellular; Verapamil | 2014 |
Mitochondrial permeability transition increases reactive oxygen species production and induces DNA fragmentation in human spermatozoa.
Topics: Calcium; Chlorides; Cyclosporine; DNA Fragmentation; Fluoresceins; Healthy Volunteers; Humans; In Situ Nick-End Labeling; Ionomycin; Male; Membrane Potential, Mitochondrial; Membrane Potentials; Microscopy, Confocal; Mitochondria; Oxidative Stress; Permeability; Reactive Oxygen Species; Spermatozoa | 2015 |
Oxidative stress damage in the protozoan parasite Trypanosoma cruzi is inhibited by Cyclosporin A.
Topics: Apoptosis; Calcineurin Inhibitors; Cell Death; Cyclophilins; Cyclosporine; Cytochromes c; Fluoresceins; Fluorescent Dyes; Hydrogen Peroxide; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Necrosis; Oxidative Stress; Protozoan Proteins; Reactive Oxygen Species; Trypanosoma cruzi | 2015 |
Cyclosporine A Treatment Abrogates Ischemia-Induced Neuronal Cell Death by Preserving Mitochondrial Integrity through Upregulation of the Parkinson's Disease-Associated Protein DJ-1.
Topics: Adenosine Triphosphate; Analysis of Variance; Animals; Cell Survival; Cerebral Cortex; Cyclosporine; Cytochromes c; DNA, Mitochondrial; Drug Administration Schedule; Embryo, Mammalian; Fluoresceins; Glucose; Glucose-6-Phosphate; Glutathione; Hypoxia; Membrane Potential, Mitochondrial; Neurons; Protein Deglycase DJ-1; Rats; Up-Regulation | 2016 |
The cyclophilin D/Drp1 axis regulates mitochondrial fission contributing to oxidative stress-induced mitochondrial dysfunctions in SH-SY5Y cells.
Topics: Cell Line, Tumor; Cyclophilins; Cyclosporine; Dynamins; Fluoresceins; Fluorescent Dyes; GTP Phosphohydrolases; Humans; Metabolic Networks and Pathways; Microtubule-Associated Proteins; Mitochondria; Mitochondrial Dynamics; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Mitochondrial Proteins; Neurodegenerative Diseases; Neurons; Neuroprotective Agents; Oxidative Stress; Peptidyl-Prolyl Isomerase F; Up-Regulation | 2017 |
Synchronism in mitochondrial ROS flashes, membrane depolarization and calcium sparks in human carcinoma cells.
Topics: Adenocarcinoma; Antioxidants; Breast Neoplasms; Calcium Signaling; Cell Line, Tumor; Colonic Neoplasms; Cyclosporine; Fluoresceins; Humans; Membrane Potential, Mitochondrial; Microscopy, Confocal; Microscopy, Fluorescence; Mitochondria; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Oxidative Stress; Photochemistry; Reactive Oxygen Species; Recombinant Proteins; Rhodamines; Single-Cell Analysis; Superoxide Dismutase | 2017 |