erythronolide-a and propadiene

erythronolide-a has been researched along with propadiene* in 1 studies

Other Studies

1 other study(ies) available for erythronolide-a and propadiene

ArticleYear
Direct Entry to 4,10-Didesmethyl (9S)-Dihydroerythronolide A via Catalytic Allene Osmylation.
    Organic letters, 2016, 06-17, Volume: 18, Issue:12

    Desmethyl erythronolides have emerged as macrolide targets that may prove effective against resistant bacteria. A five-step sequence to 4,10-didesmethyl (9S)-dihydroerythronolide A (1) from known cyclic bis[allene] 13 is reported. Key structural and mechanistic aspects of the synthesis are discussed along with catalytic allene osmylation. An improved route to 13 is also described.

    Topics: Alkadienes; Anti-Bacterial Agents; Catalysis; Erythromycin; Molecular Structure; Stereoisomerism

2016