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erythromycin propionate-n-acetylcysteinate and erythromycin

erythromycin propionate-n-acetylcysteinate has been researched along with erythromycin in 32 studies

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-19902 (6.25)18.7374
1990's0 (0.00)18.2507
2000's8 (25.00)29.6817
2010's20 (62.50)24.3611
2020's2 (6.25)2.80

Authors

AuthorsStudies
Fregnan, GB; Gazzani, G; Mazzone, A; Pasotti, D; Ricevuti, G1
De Bernardi, M; Feletti, F; Fregnan, GB; Gazzani, G1
Yarwood, SJ1
Curci, S; Gerbino, A; Hofer, AM; Pozzan, T; Ruder, WC; Zaccolo, M1
Cohen, G; Kodama, T; Makranz, C; Reichert, F; Rotshenker, S1
Conley, RR; Dwivedi, Y; Faludi, G; Mondal, AC; Palkovits, M; Pandey, GN; Rizavi, HS; Sarosi, A1
Badran, B; El Zein, N; Sariban, E1
Im, MJ; Kim, BJ; Kim, UH; Okamoto, H; Park, KH; Takasawa, S; Yim, CY1
Abel, T; Bizily, SF; Esposito, MF; Favilla, C; Kanes, SJ; Kelly, MP; Stein, JM; Vecsey, CG; Wand, G; Yang, X1
Dart, C; Davies, LM; Kamishima, T; Purves, GI; Quayle, JM1
Eggo, MC1
Bond, M; Hewer, RC; Newby, AC; Sala-Newby, GB; Wu, YJ1
Lim, Q'; Too, HP; Wan, G; Wong, YH; Zhou, L1
Bengtsson, T; Dehvari, N; Öberg, AI1
Boittin, FX; Dorchies, OM; Patthey-Vuadens, O; Reutenauer-Patte, J; Ruegg, UT1
Gratzke, C; Hennenberg, M; Rutz, B; Schmetkamp, H; Stief, CG; Strittmatter, F; Walther, S1
Barnett, SC; Boomkamp, SD; Houslay, MD; McGrath, MA1
Dezaki, K; Ishikawa, SE; Ito, K; Kakei, M; Kawakami, M; Kodera, S; Lam, NV; Rita, RS; Shimomura, K; Sugawara, H; Tominaga, M; Uchida, K; Yada, T; Yamada, H; Yosida, M1
Bailey, KL; DeVasure, JM; Heires, AJ; Nordgren, TM; Poole, JA; Romberger, DJ; Wyatt, TA1
Brandt, S; Dent, A; Medeiros, A; Serezani, CH; Wang, S; Wang, Z; Wu, H1
Boulton, S; Chen, H; Cheng, X; Mei, F; Melacini, G; Ye, N; Zhou, J; Zhu, Y1
Duan, XP; Fan, LL; Zhang, DD1
Fukada, S; Hoshino, M; Ikawa, M; Mikami, N; Miyagoe-Suzuki, Y; Nakamura, M; Ohtani, T; Sato, T; Takeda, S; Tsuchida, K; Tsujikawa, K; Uezumi, A; Watanabe, Y; Yamaguchi, M; Yamamoto, H1
Henquin, JC; Nenquin, M1
Antonetti, DA; Ramos, CJ1
Antonetti, DA; Lin, C; Liu, X; Ramos, CJ1
Ghavami, R; Kompany-Zareh, M; Omidikia, N; Sepehri, B1
Cheng, X; Robichaux, WG1
Hu, ZQ; Li, YJ; Li, ZG; Song, SD; Tang, HF; Wang, XF; Yan, CG; Zhang, ZW1
Gu, Y; Huang, LM; Li, G1
Hosoi, M; Kato, TA; Sasaki, I; Tozaki-Saitoh, H; Tsuda, M; Yamashita, T1
Hoy, JJ; Iglesias-Bartolome, R; Kuhn, S; Park, J; Salinas Parra, N1

Reviews

4 review(s) available for erythromycin propionate-n-acetylcysteinate and erythromycin

ArticleYear
Microtubule-associated proteins (MAPs) regulate cAMP signalling through exchange protein directly activated by cAMP (EPAC).
    Biochemical Society transactions, 2005, Volume: 33, Issue:Pt 6

    Topics: Acetylcysteine; Animals; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Erythromycin; Microtubule-Associated Proteins; Protein Binding; rap1 GTP-Binding Proteins; Second Messenger Systems

2005
Molecular regulation of thyroid gland function.
    Current opinion in endocrinology, diabetes, and obesity, 2010, Volume: 17, Issue:5

    Topics: Acetylcysteine; Animals; Erythromycin; Humans; Insulin; Insulin-Like Growth Factor I; Integrins; Iodides; Mice; Mitogen-Activated Protein Kinases; Peptide Hydrolases; Phosphatidylinositol 3-Kinase; Plasminogen Activators; Rats; Signal Transduction; Thyroid Gland; Thyroid Neoplasms; Vascular Endothelial Growth Factor A

2010
The role of small GTPases and EPAC-Rap signaling in the regulation of the blood-brain and blood-retinal barriers.
    Tissue barriers, 2017, 07-03, Volume: 5, Issue:3

    Topics: Acetylcysteine; Animals; Blood-Brain Barrier; Blood-Retinal Barrier; Erythromycin; Humans; Monomeric GTP-Binding Proteins; Signal Transduction

2017
Intracellular cAMP Sensor EPAC: Physiology, Pathophysiology, and Therapeutics Development.
    Physiological reviews, 2018, 04-01, Volume: 98, Issue:2

    Topics: Acetylcysteine; Animals; Cytoplasm; Erythromycin; Guanine Nucleotide Exchange Factors; Humans; Protein Transport; Receptors, Cyclic AMP; Signal Transduction

2018

Trials

2 trial(s) available for erythromycin propionate-n-acetylcysteinate and erythromycin

ArticleYear
Serum, sputum and bronchial concentrations of erythromycin in chronic bronchitis after single and multiple treatments with either propionate-N-acetylcysteinate or stearate erythromycin.
    Chemotherapy, 1988, Volume: 34, Issue:5

    Topics: Acetylcysteine; Administration, Oral; Bronchi; Bronchitis; Chronic Disease; Double-Blind Method; Erythromycin; Female; Humans; Intestinal Absorption; Male; Middle Aged; Mucus; Sputum

1988
Human pharmacokinetics of erythromycin propionate-N-acetylcysteinate: comparative evaluation with erythromycin stearate and N-acetylcysteine.
    International journal of clinical pharmacology, therapy, and toxicology, 1988, Volume: 26, Issue:9

    Topics: Acetylcysteine; Adult; Biological Availability; Erythromycin; Female; Half-Life; Humans; Male; Metabolic Clearance Rate; Middle Aged

1988

Other Studies

26 other study(ies) available for erythromycin propionate-n-acetylcysteinate and erythromycin

ArticleYear
Termination of cAMP signals by Ca2+ and G(alpha)i via extracellular Ca2+ sensors: a link to intracellular Ca2+ oscillations.
    The Journal of cell biology, 2005, Oct-24, Volume: 171, Issue:2

    Topics: Acetylcysteine; Biosensing Techniques; Calcium; Calcium Signaling; Cell Line; Cell Membrane; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Erythromycin; Fluorescence Resonance Energy Transfer; GTP-Binding Protein alpha Subunits, Gi-Go; Humans; Pertussis Toxin; Receptors, Calcium-Sensing; Sensitivity and Specificity; Signal Transduction

2005
cAMP cascade (PKA, Epac, adenylyl cyclase, Gi, and phosphodiesterases) regulates myelin phagocytosis mediated by complement receptor-3 and scavenger receptor-AI/II in microglia and macrophages.
    Glia, 2006, Volume: 53, Issue:4

    Topics: Acetylcysteine; Adenylyl Cyclases; Animals; Cells, Cultured; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme-Linked Immunosorbent Assay; Erythromycin; GTP-Binding Protein alpha Subunits, Gi-Go; Indicators and Reagents; Macrophage-1 Antigen; Macrophages; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Microglia; Myelin Sheath; Phagocytosis; Phosphoric Diester Hydrolases; Scavenger Receptors, Class A; Signal Transduction

2006
Differential and brain region-specific regulation of Rap-1 and Epac in depressed suicide victims.
    Archives of general psychiatry, 2006, Volume: 63, Issue:6

    Topics: Acetylcysteine; Adult; Aged; Brain; Brain Chemistry; Cerebellum; Depressive Disorder; Erythromycin; Female; Gene Expression Regulation; Hippocampus; Humans; Male; Middle Aged; Neuronal Plasticity; Prefrontal Cortex; rap1 GTP-Binding Proteins; RNA, Messenger; Suicide; Tissue Distribution

2006
VIP differentially activates beta2 integrins, CR1, and matrix metalloproteinase-9 in human monocytes through cAMP/PKA, EPAC, and PI-3K signaling pathways via VIP receptor type 1 and FPRL1.
    Journal of leukocyte biology, 2008, Volume: 83, Issue:4

    Topics: Acetylcysteine; Animals; Calcium; CD18 Antigens; Cell Line; CHO Cells; Cricetinae; Cricetulus; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Erythromycin; Humans; Matrix Metalloproteinase 9; Monocytes; Neutrophils; Polymerase Chain Reaction; Receptors, Complement 3b; Receptors, Formyl Peptide; Receptors, Lipoxin; Receptors, Vasoactive Intestinal Polypeptide, Type I; Signal Transduction; Transfection; Vasoactive Intestinal Peptide

2008
Generation of nicotinic acid adenine dinucleotide phosphate and cyclic ADP-ribose by glucagon-like peptide-1 evokes Ca2+ signal that is essential for insulin secretion in mouse pancreatic islets.
    Diabetes, 2008, Volume: 57, Issue:4

    Topics: Acetylcysteine; ADP-ribosyl Cyclase 1; Animals; Calcium; Cyclic ADP-Ribose; Endoplasmic Reticulum; Erythromycin; Glucagon-Like Peptide 1; Insulin; Insulin Secretion; Islets of Langerhans; Mice; Mice, Inbred ICR; Mice, Knockout; NADP; Signal Transduction

2008
Developmental etiology for neuroanatomical and cognitive deficits in mice overexpressing Galphas, a G-protein subunit genetically linked to schizophrenia.
    Molecular psychiatry, 2009, Volume: 14, Issue:4

    Topics: Acetylcysteine; Acoustic Stimulation; Age Factors; Analysis of Variance; Animals; Animals, Newborn; Antipsychotic Agents; Behavior, Animal; Brain; Cognition Disorders; Conditioning, Psychological; Cyclic AMP; Disease Models, Animal; Erythromycin; Exploratory Behavior; Fear; Female; Gene Expression Regulation, Developmental; GTP-Binding Protein alpha Subunits, Gs; Haloperidol; Male; Maze Learning; Mice; Mice, Inbred C57BL; Mice, Transgenic; Phosphodiesterase Inhibitors; Psychophysics; Reflex, Startle; Rolipram; Time Factors

2009
Exchange protein activated by cAMP (Epac) mediates cAMP-dependent but protein kinase A-insensitive modulation of vascular ATP-sensitive potassium channels.
    The Journal of physiology, 2009, Jul-15, Volume: 587, Issue:Pt 14

    Topics: Acetylcysteine; Animals; Aorta; Cells, Cultured; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Erythromycin; Ion Channel Gating; KATP Channels; Male; Membrane Potentials; Muscle, Smooth, Vascular; Myocytes, Cardiac; Rats; Rats, Wistar

2009
PKA and Epac synergistically inhibit smooth muscle cell proliferation.
    Journal of molecular and cellular cardiology, 2011, Volume: 50, Issue:1

    Topics: Acetylcysteine; Animals; Blotting, Western; Cell Proliferation; Cells, Cultured; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Erythromycin; Male; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Paxillin; Phalloidine; rap1 GTP-Binding Proteins; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Small Interfering

2011
Cyclic AMP signalling through PKA but not Epac is essential for neurturin-induced biphasic ERK1/2 activation and neurite outgrowths through GFRα2 isoforms.
    Cellular signalling, 2011, Volume: 23, Issue:11

    Topics: Acetylcysteine; Animals; Blotting, Western; Cell Line, Tumor; Cell Survival; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Erythromycin; Gene Expression Regulation; Glial Cell Line-Derived Neurotrophic Factor Receptors; Humans; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 3; Nerve Regeneration; Neurites; Neurturin; Phosphorylation; Protein Isoforms; Proto-Oncogene Proteins c-ret; Rats; Real-Time Polymerase Chain Reaction; Signal Transduction; Transfection

2011
β-Adrenergic inhibition of contractility in L6 skeletal muscle cells.
    PloS one, 2011, Volume: 6, Issue:7

    Topics: Acetylcysteine; Adrenergic beta-Agonists; Animals; Calcium; Cell Adhesion; Cells, Cultured; CHO Cells; Cricetinae; Cricetulus; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP-Dependent Protein Kinases; Erythromycin; Muscle Contraction; Muscle Fibers, Skeletal; Muscle, Skeletal; Phosphatidylinositol 3-Kinases; Phosphorylation; Potassium Channels; Protein Kinase C; Rats; Receptors, Adrenergic, beta-2; rho-Associated Kinases; Signal Transduction

2011
Urocortins improve dystrophic skeletal muscle structure and function through both PKA- and Epac-dependent pathways.
    The American journal of pathology, 2012, Volume: 180, Issue:2

    Topics: Acetylcysteine; Animals; Brefeldin A; Calcium; Calcium Channels; Cyclic AMP-Dependent Protein Kinases; Erythromycin; Group VI Phospholipases A2; Injections, Intradermal; Membrane Glycoproteins; Mice; Mice, Inbred C57BL; Muscle Contraction; Muscle Relaxation; Muscle Strength; Muscle, Skeletal; Muscular Dystrophy, Animal; Protein Kinase Inhibitors; Protein Synthesis Inhibitors; Receptors, Corticotropin-Releasing Hormone; Stromal Interaction Molecule 1; Urocortins

2012
The cAMP effector EPAC activates Elk1 transcription factor in prostate smooth muscle, and is a minor regulator of α1-adrenergic contraction.
    Journal of biomedical science, 2013, Jul-02, Volume: 20

    Topics: Acetylcysteine; Erythromycin; ets-Domain Protein Elk-1; Humans; Immunohistochemistry; Male; Muscle Contraction; Muscle, Smooth; Prostate; Receptors, Adrenergic, alpha-1; Signal Transduction; Urinary Tract

2013
Epac and the high affinity rolipram binding conformer of PDE4 modulate neurite outgrowth and myelination using an in vitro spinal cord injury model.
    British journal of pharmacology, 2014, Volume: 171, Issue:9

    Topics: Acetylcysteine; Animals; Animals, Newborn; Cells, Cultured; Dose-Response Relationship, Drug; Erythromycin; Nerve Fibers, Myelinated; Neurites; Phosphodiesterase 4 Inhibitors; Protein Binding; Rats; Rats, Sprague-Dawley; Rolipram; Spinal Cord Injuries

2014
Involvement of cAMP/EPAC/TRPM2 activation in glucose- and incretin-induced insulin secretion.
    Diabetes, 2014, Volume: 63, Issue:10

    Topics: Acetylcysteine; Animals; Calcium; Cyclic AMP; Erythromycin; Exenatide; Glucose; Incretins; Insulin; Insulin Secretion; Insulin-Secreting Cells; Male; Mice; Mice, Knockout; Peptides; Rats, Wistar; Signal Transduction; TRPM Cation Channels; Venoms

2014
cAMP-dependent protein kinase activation decreases cytokine release in bronchial epithelial cells.
    American journal of physiology. Lung cellular and molecular physiology, 2014, Oct-15, Volume: 307, Issue:8

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Acetylcysteine; ADAM Proteins; ADAM17 Protein; Animal Feed; Animals; Bronchi; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Dust; Enzyme-Linked Immunosorbent Assay; Erythromycin; Humans; Interleukin-6; Interleukin-8; Mice; Mice, Inbred C57BL; Protein Kinase C-epsilon; Swine; Tumor Necrosis Factor-alpha

2014
MicroRNA 21 is a homeostatic regulator of macrophage polarization and prevents prostaglandin E2-mediated M2 generation.
    PloS one, 2015, Volume: 10, Issue:2

    Topics: Acetylcysteine; Animals; Cell Polarity; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; Erythromycin; Female; Gene Silencing; Homeostasis; Macrophage Activation; Macrophages; Mice; Mice, Knockout; MicroRNAs; STAT3 Transcription Factor; Suppressor of Cytokine Signaling 1 Protein; Suppressor of Cytokine Signaling Proteins

2015
Biochemical and pharmacological characterizations of ESI-09 based EPAC inhibitors: defining the ESI-09 "therapeutic window".
    Scientific reports, 2015, Mar-20, Volume: 5

    Topics: Acetylcysteine; Animals; Erythromycin; Hydrazones; Isoxazoles; Mice; Mice, Knockout; Structure-Activity Relationship

2015
[The role of Epac in kidney tuble physiology].
    Sheng li ke xue jin zhan [Progress in physiology], 2015, Volume: 46, Issue:2

    Topics: Acetylcysteine; Erythromycin; Kidney Tubules

2015
Calcitonin Receptor Signaling Inhibits Muscle Stem Cells from Escaping the Quiescent State and the Niche.
    Cell reports, 2015, Oct-13, Volume: 13, Issue:2

    Topics: Acetylcysteine; Animals; Apoptosis; Cell Differentiation; Cells, Cultured; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Erythromycin; Mice; Myoblasts; Receptors, Calcitonin; Second Messenger Systems; Stem Cell Niche

2015
Sulphonylurea receptor-1, sulphonylureas and amplification of insulin secretion by Epac activation in β cells.
    Diabetes, obesity & metabolism, 2016, Volume: 18, Issue:7

    Topics: Acetylcysteine; Animals; Bucladesine; Cyclic AMP-Dependent Protein Kinases; Erythromycin; Glyburide; Hypoglycemic Agents; Insulin; Insulin Secretion; Insulin-Secreting Cells; Mice, Inbred C57BL; Sulfonylurea Compounds; Sulfonylurea Receptors; Tolbutamide

2016
The EPAC-Rap1 pathway prevents and reverses cytokine-induced retinal vascular permeability.
    The Journal of biological chemistry, 2018, 01-12, Volume: 293, Issue:2

    Topics: Acetylcysteine; Animals; Capillary Permeability; Cytokines; Erythromycin; Humans; rap1 GTP-Binding Proteins; Receptors, Vascular Endothelial Growth Factor; Retina; Signal Transduction

2018
Predictive and Descriptive CoMFA Models: The Effect of Variable Selection.
    Combinatorial chemistry & high throughput screening, 2018, Volume: 21, Issue:2

    Topics: Acetylcysteine; ADP-ribosyl Cyclase 1; Algorithms; ATPases Associated with Diverse Cellular Activities; Datasets as Topic; DNA-Binding Proteins; Erythromycin; Models, Chemical; Quantitative Structure-Activity Relationship

2018
Protective Effect of Quercetin in LPS-Induced Murine Acute Lung Injury Mediated by cAMP-Epac Pathway.
    Inflammation, 2018, Volume: 41, Issue:3

    Topics: Acetylcysteine; Acute Lung Injury; Animals; Cell Line; Cyclic AMP; Erythromycin; Inflammation; Inflammation Mediators; Lipopolysaccharides; Lung; Mice; Protective Agents; Quercetin

2018
Inflammation induces Epac-protein kinase C alpha and epsilon signaling in TRPV1-mediated hyperalgesia.
    Pain, 2018, Volume: 159, Issue:11

    Topics: Acetylcysteine; Action Potentials; Animals; Biotinylation; Capsaicin; Cells, Cultured; Disease Models, Animal; Enzyme Inhibitors; Erythromycin; Freund's Adjuvant; Ganglia, Spinal; Hyperalgesia; Inflammation; Male; Neurons; Patch-Clamp Techniques; Protein Kinase C-alpha; Protein Kinase C-epsilon; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2X4; Signal Transduction; TRPV Cation Channels

2018
Involvement of exchange protein directly activated by cAMP and tumor progression locus 2 in IL-1β production in microglial cells following activation of β-adrenergic receptors.
    Journal of pharmacological sciences, 2020, Volume: 143, Issue:3

    Topics: Acetylcysteine; Adrenergic beta-Agonists; Animals; Cells, Cultured; Erythromycin; Gene Expression; Interleukin-1beta; Isoproterenol; MAP Kinase Kinase Kinases; Mice; Microglia; Norepinephrine; Proto-Oncogene Proteins; Receptors, Adrenergic, beta; Signal Transduction; Up-Regulation

2020
Protein kinase A inhibitor proteins (PKIs) divert GPCR-Gαs-cAMP signaling toward EPAC and ERK activation and are involved in tumor growth.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2020, Volume: 34, Issue:10

    Topics: Acetylcysteine; Animals; Cell Line, Tumor; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Erythromycin; Extracellular Signal-Regulated MAP Kinases; Feedback, Physiological; Female; GTP-Binding Protein alpha Subunits; HEK293 Cells; Humans; Intracellular Signaling Peptides and Proteins; Male; MAP Kinase Signaling System; Mice; Mice, Nude; Prostatic Neoplasms

2020