erythromycin has been researched along with troleandomycin in 99 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 58 (58.59) | 18.7374 |
1990's | 22 (22.22) | 18.2507 |
2000's | 12 (12.12) | 29.6817 |
2010's | 7 (7.07) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
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Beck, WT; Schuetz, EG; Schuetz, JD | 1 |
Dantzig, AH; Ekins, S; Kim, RB; Lan, LB; Leake, BF; Schuetz, EG; Schuetz, JD; Shepard, RL; Wikel, JH; Winter, MA; Wrighton, SA; Yasuda, K | 1 |
Furuya, K; Lan, LB; Sanglard, D; Schuetz, EG; Schuetz, JD; Yasuda, K | 1 |
Dansette, PM; Fontana, E; Poli, SM | 1 |
Pratim Roy, P; Roy, K | 1 |
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
Ekins, S; Williams, AJ; Xu, JJ | 1 |
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
Chen, L; Fei, J; Mei, Y; Ren, S; Yan, SF; Zeng, J; Zhang, JZ | 1 |
Genazzani, E | 1 |
Flood, MK; Georgiew, S; Gröger, H | 1 |
Allen, JE; Gururaj, VJ; Laude, TA; Rajkumar, SV; Russo, RM | 1 |
Cocuzza, G | 1 |
Antignac, E; Fukuhara, M | 1 |
Bonfils, C; Daujat, M; Fabre, G; Fabre, I; Maurel, P; Pichard, L; Pineau, T | 1 |
Berson, A; Fisher, D; Labbe, G; Larrey, D; Loeper, J; Pessayre, D; Tinel, M | 1 |
Descatoire, V; Labbe, G; Larrey, D; Letteron, P; Loeper, J; Pessayre, D; Tinel, M | 1 |
Berezhinskaia, VV; Dolgova, GV | 1 |
Baciewicz, AM | 1 |
Franklin, MR; Ritter, JK | 1 |
Arlotto, MP; Klaassen, CD; Parkinson, A; Sonderfan, AJ | 1 |
Barra, Y; Cano, JP; Covo, J; Crevat-Pisano, P; Dragna, S; Fabre, G | 1 |
Delaforge, M; Mansuy, D; Sartori, E | 1 |
Fujita, M; Izumi, M; Nakayoshi, T; Shinkai, S | 1 |
Luherne, JY; Maitre, F; Pariente, EA | 1 |
Beaune, P; Dansette, PM; Delaforge, M; Jaouen, M; Mansuy, D; Sartori, E | 1 |
Beaune, P; Delaforge, M; Mansuy, D; Sartori, E | 1 |
Bailey, BS; Barwick, J; Guzelian, P; Hartle, HT; Maurel, P; Schuetz, EG; Watkins, PB; Wrighton, SA; Young, B | 1 |
Benhamou, JP; Funck-Brentano, C; Larrey, D; Pessayre, D | 1 |
André, P; Descotes, J; Evreux, JC | 1 |
Geslin, P; Lemerle-Gruson, S; Pesnel, G; Reinert, P; Squinazi, F | 1 |
Guzelian, PS; Maurel, P; Mendez-Picon, G; Parker, GA; Schuetz, EG; Watkins, PB; Wrighton, SA | 1 |
Willcox, RR | 1 |
von Graevenitz, A | 1 |
Ross, S | 2 |
Braun, P | 1 |
Griffith, LJ | 1 |
Frisby, BR | 1 |
Betinová, M | 1 |
Vakulenko, NA | 1 |
Carlisle, HN; Marietti, M; Saslaw, S | 1 |
Linnane, AW; Stewart, PR | 1 |
Itkin, IH; Menzel, ML | 1 |
Carlisle, HN; Saslaw, S | 1 |
Breese, BB; Disney, FA; Talpey, WB | 1 |
Micheva, M; Stoĭchev, Ts | 1 |
Pessayre, D | 1 |
Babany, G; Cobert, B; Funck-Brentano, C; Larrey, D; Pessayre, D; Tinel, M | 1 |
Brenner, M; Ebling, W; LaForce, CF; Miller, MF; Szefler, SJ | 1 |
Delaforge, M; Jaouen, M; Mansuy, D | 1 |
Leung, GW; Selenke, WM; Townley, RG | 1 |
Eckels, DD; Gershwin, ME; Scharre, KA | 1 |
Hemsworth, TC; Renton, KW | 1 |
Kupfer, D; Mani, C; Parkinson, A; Pearce, R | 1 |
Elezoglou, V; Kounenis, G; Koutsoviti-Papadopoulou, M | 1 |
Sadrieh, N; Thomas, PE | 1 |
Barra, Y; Maurel, P; Placidi, M; Rahmani, R; Sérée, E; Zhou, XJ; Zhou-Pan, XR | 1 |
Hanssen, BR; Lindstrom, TD; Wrighton, SA | 1 |
Bristol, DC; Danielson, ND; Holeman, JA; Kirzner, DH | 1 |
Oster, G; Thompson, D | 1 |
Guengerich, FP; Krivoruk, Y; Tateishi, T; Ueng, YF; Wood, AJ; Wood, M | 1 |
Flurer, CL | 1 |
Hiroki, S; Inoue, K; Shimada, T; Urano, T; Yamazaki, H | 1 |
Hiroki, S; Shimada, T; Urano, T; Yamazaki, H | 1 |
Ishizaki, T; Zhao, XJ | 1 |
Counihan, M; Duan, SX; Durol, AL; Graf, JA; Greenblatt, DJ; Harmatz, JS; Mertzanis, P; Shader, RI; von Moltke, LL; Wright, CE | 1 |
Shimada, T; Yamazaki, H | 2 |
Horbach, GJ; Van Miert, AS; Witkamp, RF; Zweers-Zeilmaker, WM | 1 |
Chen, JH; Ding, H; Kong, R; Li, QX; Peng, RX; Wang, H; Yu, JP; Zhang, YH | 1 |
Kobayashi, S; Kumai, T; Tanaka, M; Tateishi, T; Watanabe, M | 1 |
Floreani, M; Geroni, C; Napoli, E; Quintieri, L; Rosato, A; Sola, F; Zanovello, P | 1 |
Garzotti, M; Hamdan, M; Rovatti, L | 1 |
Fowler, SM; Friedberg, T; Riley, RJ; Taylor, JM; Wolf, CR | 1 |
Hoffmaster, KA; Paine, MF; Wagner, DA; Watkins, PB | 1 |
Paine, MF; Pusek, SN; Wanwimolruk, S; Watkins, PB | 1 |
Allen, C; Evans, DC; Evers, R; Hargreaves, R; Lake, BG; O'Connor, D | 1 |
HEILMAN, FR; MARTIN, WJ; NICHOLS, DR; REISCH, AJ | 1 |
FINLAND, M; KUNIN, CM; PRYLES, CV | 1 |
FINLAND, M; HIRSCH, HA; KUNIN, CM | 1 |
FINLAND, M; HIRSCH, HA | 1 |
HALL, GA; KIRBY, WM; PERRY, DM | 1 |
GILBERT, FI | 1 |
ROBERTS, EF | 1 |
SCHNEIDERMAN, FJ | 1 |
SATOMI, M | 1 |
JERVEY, L | 1 |
MARTIN, WJ | 1 |
KATSU, M; NORMURA, K; OSUGA, H; YAMAMOTO, I | 1 |
WARNER, RS | 1 |
ISENBERG, HD | 1 |
COLVILLE, JM; COX, F; QUINN, EL | 1 |
ROBINSON, MM | 1 |
Hall, K; Meredith, S; Murray, KT; Narasimhulu, SS; Ray, WA; Stein, CM | 1 |
Berry, AJ; Grime, K; Kenny, JR; McGinnity, DF; Riley, RJ | 1 |
Allas, U; Tenson, T | 1 |
Chen, Y; Fretland, AJ; Liu, L; Monshouwer, M | 1 |
8 review(s) available for erythromycin and troleandomycin
Article | Year |
---|---|
Cytochrome p450 enzymes mechanism based inhibitors: common sub-structures and reactivity.
Topics: Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Inhibitors; Humans; Isoenzymes; Structure-Activity Relationship; Terminology as Topic | 2005 |
[Macrolide antibiotics and their use in combined pharmacotherapy].
Topics: Bacterial Infections; Depression, Chemical; Drug Interactions; Drug Therapy, Combination; Erythromycin; Humans; Metabolic Clearance Rate; Theophylline; Troleandomycin | 1989 |
Carbamazepine drug interactions.
Topics: Carbamazepine; Cimetidine; Dextropropoxyphene; Drug Interactions; Erythromycin; Humans; Isoniazid; Lithium; Phenobarbital; Phenytoin; Primidone; Protein Binding; Troleandomycin; Valproic Acid; Warfarin | 1986 |
Pharmacokinetic drug interactions with macrolide antibiotics.
Topics: Adrenal Cortex Hormones; Anti-Bacterial Agents; Antipyrine; Carbamazepine; Drug Interactions; Ergot Alkaloids; Erythromycin; Humans; Kinetics; Pharmaceutical Preparations; Theophylline; Troleandomycin | 1985 |
Erythromycin, oleandomycin and triacetyloleandomycin.
Topics: Anti-Bacterial Agents; Cardiovascular Diseases; Erythromycin; Gastrointestinal Diseases; Humans; Oleandomycin; Respiratory Tract Infections; Troleandomycin | 1968 |
Hepatotoxicity of erythromycin.
Topics: Chemical and Drug Induced Liver Injury; Drug Hypersensitivity; Erythromycin; Humans; Liver; Liver Diseases; Liver Function Tests; Troleandomycin | 1969 |
Effects of macrolide antibiotics on drug metabolism in rats and in humans.
Topics: Amines; Animals; Anti-Bacterial Agents; Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme System; Enzyme Induction; Erythromycin; Humans; Leucomycins; Oxidation-Reduction; Pharmaceutical Preparations; Rats; Species Specificity; Troleandomycin | 1983 |
NEWER ANTIMICROBIAL AGENTS HAVING CURRENT OR POTENTIAL CLINICAL APPLICATION.
Topics: Amphotericin B; Anti-Bacterial Agents; Antifungal Agents; Cephalothin; Colistin; Cycloserine; Demeclocycline; Erythromycin; Gentamicins; Griseofulvin; Humans; Kanamycin; Methicillin; Novobiocin; Oxacillin; Paromomycin; Penicillin V; Penicillins; Pharmacology; Ristocetin; Staphylococcal Infections; Toxicology; Troleandomycin; Vancomycin | 1964 |
4 trial(s) available for erythromycin and troleandomycin
Article | Year |
---|---|
'Triple tetracycline' in the treatment of non-gonococcal urethritis in males.
Topics: Anti-Bacterial Agents; Chlortetracycline; Clinical Trials as Topic; Demeclocycline; England; Erythromycin; Humans; Leucomycins; Male; Tetracycline; Troleandomycin; Urethritis; Wales | 1972 |
B-hemolytic streptococcal illness. A comparison of the effectiveness of penicillin G, triacetyloleandomycin, and erythromycin estolate.
Topics: Child; Child, Preschool; Clinical Trials as Topic; Erythromycin; Humans; Penicillin G; Streptococcal Infections; Troleandomycin | 1966 |
Inhibition of triazolam clearance by macrolide antimicrobial agents: in vitro correlates and dynamic consequences.
Topics: Administration, Oral; Anti-Bacterial Agents; Aryl Hydrocarbon Hydroxylases; Azithromycin; Clarithromycin; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Double-Blind Method; Erythromycin; Humans; Hypnotics and Sedatives; In Vitro Techniques; Microsomes, Liver; Oxidoreductases, N-Demethylating; Time Factors; Triazolam; Troleandomycin | 1998 |
Is quinine a suitable probe to assess the hepatic drug-metabolizing enzyme CYP3A4?
Topics: Administration, Oral; Adult; Aged; Antimalarials; Area Under Curve; Breath Tests; Cross-Over Studies; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Erythromycin; Female; Humans; Liver; Male; Metabolic Clearance Rate; Middle Aged; Molecular Probes; Ovarian Neoplasms; Quinidine; Quinine; Troleandomycin | 2002 |
87 other study(ies) available for erythromycin and troleandomycin
Article | Year |
---|---|
Modulators and substrates of P-glycoprotein and cytochrome P4503A coordinately up-regulate these proteins in human colon carcinoma cells.
Topics: Adenocarcinoma; ATP Binding Cassette Transporter, Subfamily B, Member 1; Base Sequence; Blotting, Northern; Cell Line; Clotrimazole; Colonic Neoplasms; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme System; Dexamethasone; DNA Primers; Doxorubicin; Gene Expression Regulation, Neoplastic; Humans; Midazolam; Mixed Function Oxygenases; Molecular Sequence Data; Multigene Family; Phenobarbital; Phenytoin; Polymerase Chain Reaction; Rifampin; Tumor Cells, Cultured; Verapamil | 1996 |
Three-dimensional quantitative structure-activity relationships of inhibitors of P-glycoprotein.
Topics: Animals; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Caco-2 Cells; Ergonovine; Fluoxetine; Humans; Models, Molecular; Oxytocics; Protein Conformation; Selective Serotonin Reuptake Inhibitors; Structure-Activity Relationship; Swine; Transfection; Vinblastine | 2002 |
Interaction of cytochrome P450 3A inhibitors with P-glycoprotein.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Cell Line; Cells, Cultured; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dihydroergocryptine; Drug Interactions; Enzyme Inhibitors; Fluconazole; Humans; Mice; Mice, Knockout; Microsomes, Liver; Oxidoreductases, N-Demethylating; Recombinant Proteins; Reserpine; Swine; Tissue Distribution; Transfection; Vinblastine | 2002 |
Comparative chemometric modeling of cytochrome 3A4 inhibitory activity of structurally diverse compounds using stepwise MLR, FA-MLR, PLS, GFA, G/PLS and ANN techniques.
Topics: Algorithms; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Enzyme Inhibitors; Factor Analysis, Statistical; Least-Squares Analysis; Linear Models; Models, Molecular; Neural Networks, Computer; Quantitative Structure-Activity Relationship; Reproducibility of Results | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
Discovery and characterization of novel, potent, and selective cytochrome P450 2J2 inhibitors.
Topics: Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Discovery; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Kinetics; Microsomes, Liver; Models, Molecular; Molecular Dynamics Simulation; Substrate Specificity | 2013 |
The pharmacological and pharmacokinetic properties of troleandomycin.
Topics: Animals; Chemical Phenomena; Chemistry; Enzyme Induction; Erythromycin; Humans; Kinetics; Lipoproteins, LDL; Liver; Mice; Oleandomycin; Rats; Tissue Distribution; Triglycerides; Troleandomycin | 1975 |
Comparative serum and tonsillar tissue concentration of two macrolides.
Topics: Adult; Erythromycin; Humans; Palatine Tonsil; Troleandomycin | 1978 |
Triacetyloleandomycin in streptococcal throat infections. A reappraisal of an older antibiotic.
Topics: Cephalosporins; Child; Child, Preschool; Erythromycin; Female; Humans; Laryngitis; Lincomycin; Male; Streptococcal Infections; Troleandomycin | 1976 |
The microbiological characteristics of troleandomycin.
Topics: Anti-Bacterial Agents; Bacteria; Chemical Phenomena; Chemistry; Drug Resistance, Microbial; Erythromycin; Mitochondria; Oleandomycin; Troleandomycin | 1975 |
Identification of a constitutive form of cytochrome P-450 with high activity towards macrolide antibiotics in Syrian golden hamster liver.
Topics: Animals; Anti-Bacterial Agents; Cricetinae; Cytochrome P-450 Enzyme System; Erythromycin; Isoenzymes; Male; Mesocricetus; Microsomes, Liver; Rats; Species Specificity; Substrate Specificity; Troleandomycin | 1992 |
Induction protocols for cytochromes P450IIIA in vivo and in primary cultures of animal and human hepatocytes.
Topics: Animals; Anti-Bacterial Agents; Cells, Cultured; Culture Techniques; Cytochrome P-450 Enzyme System; Dexamethasone; Enzyme Induction; Erythromycin; Female; Fetus; Humans; Liver; Male; Pregnancy; Pregnenolone Carbonitrile; Rabbits; Rats; Rats, Inbred Strains; Rifampin; Sex Characteristics; Troleandomycin | 1991 |
Inhibition of rat liver estrogen 2/4-hydroxylase activity by troleandomycin: comparison with erythromycin and roxithromycin.
Topics: Animals; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dexamethasone; Erythromycin; Ferricyanides; Male; Microsomes, Liver; Rats; Rats, Inbred Strains; Roxithromycin; Steroid Hydroxylases; Troleandomycin | 1990 |
Effects of clarithromycin on cytochrome P-450. Comparison with other macrolides.
Topics: Animals; Clarithromycin; Cytochrome P-450 Enzyme System; Dealkylation; Dexamethasone; Enzyme Induction; Erythromycin; Iron; Isoenzymes; Male; Rats; Rats, Inbred Strains; Troleandomycin | 1989 |
Clotrimazole induction of cytochrome P-450: dose-differentiated isozyme induction.
Topics: Aniline Hydroxylase; Animals; Clotrimazole; Cytochrome P-450 Enzyme System; Dexamethasone; Dose-Response Relationship, Drug; Enzyme Induction; Erythromycin; Glucuronosyltransferase; Imidazoles; Male; Microsomes, Liver; Mixed Function Oxygenases; Oxidoreductases, O-Demethylating; Rats; Troleandomycin | 1987 |
Studies on the pregnenolone-16 alpha-carbonitrile-inducible form of rat liver microsomal cytochrome P-450 and UDP-glucuronosyltransferase.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 Enzyme System; Enzyme Induction; Erythromycin; Female; Glucuronosyltransferase; Isoenzymes; Kinetics; Male; Microsomes, Liver; Pregnenolone Carbonitrile; Rats; Steroid Hydroxylases; Troleandomycin | 1987 |
Involvement of the macrolide antibiotic inducible cytochrome P-450 LM3c in the metabolism of midazolam by microsomal fractions prepared from rabbit liver.
Topics: Animals; Cyclosporins; Cytochrome P-450 Enzyme System; Enzyme Induction; Erythromycin; In Vitro Techniques; Isoenzymes; Male; Microsomes, Liver; Midazolam; Rabbits; Rifampin; Troleandomycin | 1988 |
In vivo and in vitro effects of a new macrolide antibiotic roxithromycin on rat liver cytochrome P-450: comparison with troleandomycin and erythromycin.
Topics: Animals; Chemical Phenomena; Chemistry; Cytochrome P-450 Enzyme System; Erythromycin; Leucomycins; Liver; Male; Rats; Rats, Inbred Strains; Troleandomycin | 1988 |
Comparative study on effects of 14- and 16-membered macrolides on gastrointestinal motility in unanaesthetized dogs.
Topics: Administration, Oral; Animals; Anti-Bacterial Agents; Dogs; Erythromycin; Female; Gastrointestinal Motility; Injections, Intravenous; Leucomycins; Structure-Activity Relationship; Troleandomycin | 1988 |
[Crossed hepatotoxicity of erythromycin propionate and troleandomycin?].
Topics: Adult; Chemical and Drug Induced Liver Injury; Drug Interactions; Erythromycin; Humans; Male; Troleandomycin | 1988 |
Drug interactions with macrolide antibiotics: specificity of pseudo-suicide inhibition and induction of cytochrome P-450.
Topics: Animals; Biotransformation; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Induction; Erythromycin; In Vitro Techniques; Liver; Pharmaceutical Preparations; Rats; Structure-Activity Relationship; Troleandomycin | 1986 |
Some erythromycin derivatives are strong inducers in rats of a cytochrome P-450 very similar to that induced by 16 alpha-pregnenolone carbonitrile.
Topics: Animals; Cytochrome P-450 Enzyme System; Erythromycin; In Vitro Techniques; Male; Microsomes, Liver; Pregnenolone Carbonitrile; Rats; Rats, Inbred Strains; Troleandomycin | 1985 |
Demonstration in multiple species of inducible hepatic cytochromes P-450 and their mRNAs related to the glucocorticoid-inducible cytochrome P-450 of the rat.
Topics: Animals; Base Sequence; Cricetinae; Cytochrome P-450 Enzyme System; Dexamethasone; Enzyme Induction; Erythromycin; Female; Gerbillinae; Glucocorticoids; Liver; Male; Mesocricetus; Phenobarbital; Pregnenolone Carbonitrile; Rabbits; Rats; Rats, Inbred Strains; Rifampin; RNA, Messenger; Species Specificity; Troleandomycin | 1985 |
Drug interactions and hepatitis produced by some macrolide antibiotics.
Topics: Animals; Anti-Bacterial Agents; Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Induction; Erythromycin; Humans; Liver; Microsomes, Liver; Rats; Structure-Activity Relationship; Troleandomycin | 1985 |
[Haemophilus influenzae infections in infants and macrolides. Importance of the choice of an effective antibiotic and compliance with its administration schedule].
Topics: Amoxicillin; Child, Preschool; Erythromycin; Haemophilus influenzae; Humans; Infant; Leucomycins; Meningitis, Haemophilus; Respiratory Tract Infections; Troleandomycin | 1985 |
Identification of an inducible form of cytochrome P-450 in human liver.
Topics: Amino Acid Sequence; Cytochrome P-450 Enzyme System; Dexamethasone; Enzyme Induction; Erythromycin; Humans; Immunosorbent Techniques; Liver; Substrate Specificity; Troleandomycin | 1985 |
Sensitivity studies on Serratia strains from clinical specimens.
Topics: Ampicillin; Anti-Bacterial Agents; Bacteriological Techniques; Cephalothin; Chloramphenicol; Colistin; Erythromycin; Furazolidone; Humans; Kanamycin; Nalidixic Acid; Neomycin; Nitrofurantoin; Nitrofurazone; Novobiocin; Penicillin G; Penicillin Resistance; Serratia marcescens; Streptomycin; Sulfadiazine; Tetracycline; Troleandomycin | 1967 |
Development of resistance to kanamycin.
Topics: Bacitracin; Chloramphenicol; Cloxacillin; Enterobacter; Erythromycin; Escherichia coli; Kanamycin; Methicillin; Neomycin; Novobiocin; Penicillin Resistance; Penicillins; Proteus; Pseudomonas aeruginosa; Staphylococcus; Tetracycline; Troleandomycin | 1966 |
A laboratory comparison of tri-acetyl oleandomycin and nine other antibiotics.
Topics: Anti-Bacterial Agents; Chloramphenicol; Clostridium; Cloxacillin; Enterococcus faecalis; Erythromycin; Haemophilus influenzae; Lincomycin; Novobiocin; Penicillin G; Penicillin Resistance; Staphylococcus; Streptococcus; Streptomycin; Tetracycline; Troleandomycin; Vancomycin | 1968 |
[Effect of tetracyclines, macrolide antibiotics, and sigmamycin on staphylococci in vitro].
Topics: Anti-Bacterial Agents; Chlortetracycline; Demeclocycline; Drug Resistance, Microbial; Erythromycin; Leucomycins; Oleandomycin; Oxytetracycline; Staphylococcus; Tetracycline; Troleandomycin | 1968 |
[Unification of the method for determination of biological activity of antibiotics by means of single test culture].
Topics: Anti-Bacterial Agents; Bacillus; Bacillus subtilis; Biological Assay; Depression, Chemical; Drug Resistance, Microbial; Erythromycin; Methods; Oleandomycin; Streptomycin; Troleandomycin | 1968 |
Therapy of staphylococcal infections in monkeys. IV. Further comparison of triacetyloleandomycin and erythromycins.
Topics: Animals; Aspartate Aminotransferases; Blood Bactericidal Activity; C-Reactive Protein; Erythromycin; Haplorhini; Penicillin Resistance; Staphylococcal Infections; Staphylococcus; Troleandomycin | 1969 |
Staphylococcal infections in nurseries.
Topics: Ampicillin; Bacitracin; Cephalosporins; Chloramphenicol; Cross Infection; Erythromycin; Humans; Infant, Newborn; Infant, Newborn, Diseases; Infant, Premature, Diseases; Methicillin; Novobiocin; Penicillin G; Sepsis; Tetracycline; Troleandomycin; Vancomycin | 1966 |
The inhibition of chlorophyll formation in Euglena by antibiotics which inhibit bacterial and mitochondrial protein synthesis.
Topics: Chloramphenicol; Chlorophyll; Chloroplasts; Erythromycin; Euglena; Leucomycins; Lincomycin; Photosynthesis; Tetracycline; Troleandomycin | 1967 |
The use of macrolide antibiotic substances in the treatment of asthma.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Cortex Hormones; Asthma; Bronchography; Bronchoscopy; Chloramphenicol; Eosinophils; Erythromycin; Humans; Skin Tests; Sputum; Troleandomycin | 1970 |
Serum antibacterial activity after oral suspensions and capsules of triacetyloleandomycin and erythromycin estolate.
Topics: Dosage Forms; Erythromycin; Humans; Staphylococcus; Streptococcus; Troleandomycin | 1970 |
[Effect of triacetyloleandomycin, erythromycin and spiramycin on mono-oxygenase activity].
Topics: Animals; Cytochrome P-450 Enzyme System; Electron Transport; Erythromycin; Leucomycins; Liver; Male; Mixed Function Oxygenases; Organ Size; Rats; Rats, Inbred Strains; Troleandomycin | 1984 |
Inactivation of cytochrome P-450 by a troleandomycin metabolite. Protective role of glutathione.
Topics: Animals; Cobalt; Cytochrome P-450 Enzyme System; Enzyme Induction; Erythromycin; Glutathione; Male; Methylcholanthrene; Oleandomycin; Phenobarbital; Rats; Rats, Inbred Strains; Troleandomycin | 1983 |
Inhibition of methylprednisolone elimination in the presence of erythromycin therapy.
Topics: Adolescent; Alanine Transaminase; Aspartate Aminotransferases; Asthma; Child; Erythromycin; Female; Humans; Male; Methylprednisolone; Statistics as Topic; Troleandomycin | 1983 |
Dual effects of macrolide antibiotics on rat liver cytochrome P-450. Induction and formation of metabolite-complexes: a structure-activity relationship.
Topics: Animals; Anti-Bacterial Agents; Cytochrome P-450 Enzyme System; Erythromycin; Liver; Male; Phenobarbital; Rats; Rats, Inbred Strains; Structure-Activity Relationship; Troleandomycin | 1983 |
Nonantibiotic effects of macrolide antibiotics of the oleandomycin-erythromycin group with special reference to their "steroid-sparing" effects.
Topics: Anaphylaxis; Animals; Aspartate Aminotransferases; Carrageenan; Epinephrine; Erythromycin; Erythromycin Estolate; Female; Glucose Tolerance Test; Glycogen; Guinea Pigs; Histamine; Hydrocortisone; Inflammation; Liver; Methylprednisolone; Mice; Rats; Steroids; Troleandomycin | 1980 |
Depression of colony formation by human thymus-derived lymphocytes with rifampin and other antimicrobial agents.
Topics: Adult; Antifungal Agents; Chloramphenicol; Clindamycin; Clone Cells; Erythromycin; Humans; Mycobacterium; Rifampin; T-Lymphocytes; Troleandomycin; Vancomycin | 1981 |
Depression of theophylline metabolism and elimination by troleandomycin and erythromycin.
Topics: Animals; Drug Interactions; Erythromycin; In Vitro Techniques; Male; Metabolic Clearance Rate; Microsomes, Liver; Rabbits; Theophylline; Troleandomycin; Uric Acid | 1981 |
Involvement of cytochrome P4503A in catalysis of tamoxifen activation and covalent binding to rat and human liver microsomes.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Benzimidazoles; Biotransformation; Chickens; Cricetinae; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Erythromycin; Female; Humans; Hydrocortisone; Immunoglobulin G; Male; Mesocricetus; Methylcholanthrene; Metyrapone; Mice; Microsomes, Liver; Mixed Function Oxygenases; Phenobarbital; Pregnenolone Carbonitrile; Proadifen; Protein Binding; Rats; Rats, Sprague-Dawley; Species Specificity; Tamoxifen; Troleandomycin | 1994 |
Comparative study of erythromycin, troleandomycin and tylosin on the rabbit intestine.
Topics: Animals; Dose-Response Relationship, Drug; Erythromycin; Female; Intestines; Male; Muscle Contraction; Muscle, Smooth; Rabbits; Troleandomycin; Tylosin | 1994 |
Characterization of rat cytochrome P450 isozymes involved in the covalent binding of cyclosporin A to microsomal proteins.
Topics: Aging; Animals; Antibodies, Monoclonal; Aryl Hydrocarbon Hydroxylases; Blotting, Western; Catalysis; Cyclosporine; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Induction; Erythromycin; Female; Glutathione; Isoenzymes; Kidney; Male; Mannitol; Microsomes; Microsomes, Liver; Oxidoreductases, N-Demethylating; Protein Binding; Proteins; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Testosterone; Tritium; Troleandomycin | 1994 |
Involvement of human liver cytochrome P450 3A in vinblastine metabolism: drug interactions.
Topics: Adolescent; Adult; Antibodies; Base Sequence; Binding, Competitive; Biotransformation; Blotting, Western; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme System; Drug Interactions; Erythromycin; Female; Humans; Ketoconazole; Kinetics; Male; Microsomes, Liver; Middle Aged; Mixed Function Oxygenases; Molecular Sequence Data; Multigene Family; Oligodeoxyribonucleotides; RNA, Messenger; Troleandomycin; Vinblastine; Vindesine | 1993 |
Cytochrome P-450 complex formation by dirithromycin and other macrolides in rat and human livers.
Topics: Animals; Anti-Bacterial Agents; Cytochrome P-450 Enzyme System; Dexamethasone; Erythromycin; Humans; In Vitro Techniques; Macrolides; Male; Microsomes, Liver; NADP; Phenobarbital; Phenytoin; Rats; Rats, Sprague-Dawley; Troleandomycin | 1993 |
Simple methods for the qualitative identification and quantitative determination of macrolide antibiotics.
Topics: Anti-Bacterial Agents; Chromatography, Gas; Erythromycin; Oleandomycin; Spectrophotometry, Ultraviolet; Spiramycin; Sulfuric Acids; Troleandomycin; Tylosin | 1993 |
Use of terfenadine and contraindicated drugs.
Topics: Anti-Bacterial Agents; Antifungal Agents; Clarithromycin; Contraindications; Drug Interactions; Drug Utilization; Erythromycin; Histamine H1 Antagonists; Humans; Itraconazole; Ketoconazole; Pharmaceutical Services; Product Labeling; Retrospective Studies; Terfenadine; Troleandomycin | 1996 |
Identification of human liver cytochrome P-450 3A4 as the enzyme responsible for fentanyl and sufentanil N-dealkylation.
Topics: Analgesics, Opioid; Animals; Antibodies; Antibody Specificity; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dealkylation; Enzyme Inhibitors; Erythromycin; Fentanyl; Humans; Kinetics; Liver; Microsomes, Liver; Mixed Function Oxygenases; Norpregnenes; Rabbits; Sufentanil; Troleandomycin | 1996 |
Analysis of macrolide antibiotics by capillary electrophoresis.
Topics: Acetonitriles; Anti-Bacterial Agents; Buffers; Carbohydrate Sequence; Cholic Acid; Cholic Acids; Clarithromycin; Electrophoresis, Capillary; Erythromycin; Molecular Sequence Data; Molecular Structure; Oleandomycin; Spiramycin; Troleandomycin | 1996 |
Effects of roxithromycin, erythromycin and troleandomycin on their N-demethylation by rat and human cytochrome P450 enzymes.
Topics: Animals; Anti-Bacterial Agents; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Dealkylation; Enzyme Induction; Erythromycin; Humans; Isoenzymes; Microsomes, Liver; Rats; Roxithromycin; Species Specificity; Troleandomycin | 1996 |
Effects of erythromycin and roxithromycin on oxidation of testosterone and nifedipine catalyzed by CYP3A4 in human liver microsomes.
Topics: Animals; Anti-Bacterial Agents; Catalysis; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Erythromycin; Humans; Ketoconazole; Male; Microsomes, Liver; Mixed Function Oxygenases; Nifedipine; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Roxithromycin; Testosterone; Troleandomycin | 1996 |
Metabolic interactions of selected antimalarial and non-antimalarial drugs with the major pathway (3-hydroxylation) of quinine in human liver microsomes.
Topics: Anti-Infective Agents; Antimalarials; Chromatography; Cytochrome P-450 Enzyme System; Doxycycline; Drug Interactions; Erythromycin; Humans; Hydroxylation; Ketoconazole; Microsomes, Liver; Nifedipine; Omeprazole; Primaquine; Quinine; Tetracycline; Troleandomycin | 1997 |
Comparative studies of in vitro inhibition of cytochrome P450 3A4-dependent testosterone 6beta-hydroxylation by roxithromycin and its metabolites, troleandomycin, and erythromycin.
Topics: Anti-Bacterial Agents; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Erythromycin; Humans; Hydroxylation; Methylation; Microsomes, Liver; Mixed Function Oxygenases; Recombinant Proteins; Roxithromycin; Steroid Hydroxylases; Troleandomycin | 1998 |
Formation in vitro of an inhibitory cytochrome P450 x Fe2+-metabolite complex with roxithromycin and its decladinosyl, O-dealkyl and N-demethyl metabolites in rat liver microsomes.
Topics: Animals; Anti-Bacterial Agents; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dexamethasone; Erythromycin; Iron; Male; Methylation; Microsomes, Liver; Oxidoreductases, N-Demethylating; Rats; Rats, Sprague-Dawley; Roxithromycin; Testosterone; Troleandomycin | 1998 |
In vitro complex formation and inhibition of hepatic cytochrome P450 activity by different macrolides and tiamulin in goats and cattle.
Topics: Animals; Anti-Bacterial Agents; Aryl Hydrocarbon Hydroxylases; Cattle; Cell Line; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Diterpenes; Erythromycin; Female; Goats; Humans; Hydroxylation; Ivermectin; Macrolides; Microsomes, Liver; Oxidoreductases, N-Demethylating; Rats; Spiramycin; Testosterone; Troleandomycin; Tylosin | 1999 |
Demethylation capacity of human fetal adrenal mitochondrial cytochrome P-450 in vitro.
Topics: Adrenal Glands; Aminopyrine; Benzphetamine; Cytochrome P-450 Enzyme System; Erythromycin; Fetus; Formaldehyde; Humans; Microsomes, Liver; Mitochondria; Troleandomycin | 1999 |
Role of CYP3A in bromperidol metabolism in rat in vitro and in vivo.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dexamethasone; Enzyme Inhibitors; Erythromycin; Half-Life; Haloperidol; Immune Sera; Male; Microsomes, Liver; Oxidoreductases, N-Demethylating; Propionates; Quinine; Rats; Rats, Sprague-Dawley; Steroid Hydroxylases; Theophylline; Troleandomycin | 1999 |
In vivo antitumor activity and host toxicity of methoxymorpholinyl doxorubicin: role of cytochrome P450 3A.
Topics: Animals; Anti-Bacterial Agents; Antibiotics, Antineoplastic; Antineoplastic Agents; Aryl Hydrocarbon Hydroxylases; Bone Marrow; Coculture Techniques; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Doxorubicin; Erythromycin; Female; Leukemia, Experimental; Liver; Liver Neoplasms, Experimental; Methylation; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Microsomes, Liver; NADP; Neoplasm Transplantation; Neoplasms, Experimental; Oxidoreductases, N-Demethylating; Pregnenolone Carbonitrile; Protein Synthesis Inhibitors; Time Factors; Troleandomycin; Tumor Cells, Cultured | 2000 |
Coupling of a supercritical fluid chromatography system to a hybrid (Q-TOF 2) mass spectrometer: on-line accurate mass measurements.
Topics: Anti-Bacterial Agents; Carbon Dioxide; Chromatography, Liquid; Erythromycin; Hydrocortisone; Macrolides; Mass Spectrometry; Oleandomycin; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Testosterone; Troleandomycin | 2001 |
CYP3A4 active site volume modification by mutagenesis of leucine 211.
Topics: Amino Acid Substitution; Anti-Anxiety Agents; Anti-Bacterial Agents; Binding Sites; Coumarins; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Diazepam; Enzyme Activation; Enzyme Inhibitors; Erythromycin; Hydroxylation; Kinetics; Leucine; Mixed Function Oxygenases; Mutagenesis, Site-Directed; Oxidation-Reduction; Structure-Activity Relationship; Substrate Specificity; Testosterone; Troleandomycin | 2002 |
Cytochrome P450 3A4 and P-glycoprotein mediate the interaction between an oral erythromycin breath test and rifampin.
Topics: Adult; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Breath Tests; Carbon Dioxide; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Erythromycin; Female; Humans; Male; Rifampin; Troleandomycin | 2002 |
Eletriptan metabolism by human hepatic CYP450 enzymes and transport by human P-glycoprotein.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Brain; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Erythromycin; Genes, MDR; Humans; Indoles; Injections, Intravenous; Male; Mice; Mice, Mutant Strains; Miconazole; Microsomes, Liver; Oxazolidinones; Oxidoreductases, N-Demethylating; Phenotype; Piperidines; Pyrrolidines; Recombinant Proteins; Statistics as Topic; Sumatriptan; Triazoles; Troleandomycin; Tryptamines | 2003 |
Triacetyloleandomycin and erythromycin in serum; comparison of concentrations and of antibacterial effects.
Topics: Anti-Bacterial Agents; Antibiotics, Antitubercular; Dermatologic Agents; Erythromycin; Humans; Troleandomycin | 1958 |
Antibacterial activity of serum after oral doses of triacetyloleandomycin, erythromycin, potassium penicillin V and penicillin V.
Topics: Anti-Bacterial Agents; Dermatologic Agents; Erythromycin; Humans; Penicillin V; Penicillins; Potassium; Troleandomycin | 1958 |
Antibacterial activity of serum of normal men after oral doses of erythromycin propionate and triacetyloleandomycin.
Topics: Anti-Bacterial Agents; Antibiotics, Antitubercular; Blood; Dermatologic Agents; Erythromycin; Humans; Troleandomycin | 1959 |
Effect of food on the absorption of erythromycin propionate, erythromycin stearate and triacetyloleandomycin.
Topics: Anti-Bacterial Agents; Erythromycin; Food; Humans; Troleandomycin | 1959 |
Triacetyloleandomycin and erythromycin: a comparison of in vitro activity and of blood levels obtained after oral administration.
Topics: Administration, Oral; Anti-Bacterial Agents; Erythromycin; Humans; In Vitro Techniques; Troleandomycin | 1959 |
Cholestatic hepatitis caused by esters of erythromycin and oleandomycin.
Topics: Drug Hypersensitivity; Erythromycin; Esters; Hepatitis; Humans; Oleandomycin; Troleandomycin | 1962 |
Antibiotics and newer advances with emphasis on the synthetic penicilins.
Topics: Anti-Bacterial Agents; Chloramphenicol; Colistin; Demeclocycline; Dihydrostreptomycin Sulfate; Erythromycin; Kanamycin; Methicillin; Penicillin V; Penicillins; Streptomycin; Troleandomycin; Vancomycin | 1962 |
CASE REPORTS ON STAPHYLOCOCCAL PNEUMONIA AND EMPYEMA IN INFANCY.
Topics: Blood Transfusion; Drainage; Empyema; Erythromycin; Humans; Infant; Lung Abscess; Methicillin; Pneumonia; Pneumonia, Staphylococcal; Pneumothorax; Staphylococcal Infections; Troleandomycin | 1963 |
[FEVER IN CHILDREN. (2)].
Topics: Anti-Bacterial Agents; Antibiotics, Antitubercular; Child; Chloramphenicol; Communicable Diseases; Erythromycin; Fever; Infant; Infant, Newborn; Infections; Oxytetracycline; Penicillin G; Penicillins; Propionates; Sulfadimethoxine; Sulfamethoxypyridazine; Sulfisomidine; Sulfonamides; Troleandomycin | 1963 |
TRIACETYLOLEANDOMYCIN.
Topics: Anti-Bacterial Agents; Chloramphenicol; Drug Resistance; Drug Resistance, Microbial; Erythromycin; Humans; Penicillins; Pharmacology; Pneumococcal Infections; Staphylococcal Infections; Streptococcal Infections; Tetracycline; Troleandomycin | 1964 |
[SUCESSFUL TREATMENT OF A CASE OF PNEUMOCOCCAL MENINGITIS WITH LONG-TERM COMBINED THERAPY OF ANTIBIOTICS AND ADRENAL CORTEX HORMONES].
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Anti-Bacterial Agents; Dexamethasone; Drug Therapy; Erythromycin; Humans; Meningitis; Meningitis, Pneumococcal; Penicillins; Prednisolone; Streptococcus pneumoniae; Streptomycin; Tetracycline; Troleandomycin | 1964 |
CLINICAL STUDY OF NAFCILLIN FOR STAPHYLOCOCCAL SOFT TISSUE AND MUCOUS MEMBRANE INFECTIONS IN A GENERAL PRACTICE.
Topics: Abscess; Animals; Carbuncle; Cellulitis; Child; Chloramphenicol; Drug Resistance; Drug Resistance, Microbial; Erythromycin; Furunculosis; General Practice; Humans; Mastoiditis; Mucous Membrane; Nafcillin; Osteomyelitis; Parotitis; Penicillin G; Penicillins; Peritonsillar Abscess; Staphylococcal Infections; Staphylococcus; Troleandomycin; Ulcer | 1964 |
THE CONSISTENCY OF IN VITRO MICROBIAL RESPONSE: A SURVEY OF THE AMERICAS, EUROPE AND JAPAN.
Topics: Anti-Bacterial Agents; Bacteriophages; Chloramphenicol; Drug Resistance, Microbial; Erythromycin; Europe; Humans; In Vitro Techniques; Japan; Mexico; Penicillins; Pharmacology; South America; Staphylococcus; Streptococcus; Streptococcus pneumoniae; Tetracycline; Troleandomycin | 1965 |
Comparative studies of erythromycin propionate, erythromycin stearate, and triacetyloleandomycin.
Topics: Erythromycin; Oleandomycin; Troleandomycin | 1960 |
Hepatic dysfunction associated with triacetyloleandomycin and propionyl erythromycin ester lauryl sulfate.
Topics: Erythromycin; Liver Diseases; Oleandomycin; Sodium Dodecyl Sulfate; Troleandomycin | 1962 |
Oral erythromycin and the risk of sudden death from cardiac causes.
Topics: Administration, Oral; Adult; Aged; Amoxicillin; Anti-Bacterial Agents; Aryl Hydrocarbon Hydroxylases; Calcium Channel Blockers; Confounding Factors, Epidemiologic; Cytochrome P-450 CYP3A; Death, Sudden, Cardiac; Diltiazem; Drug Interactions; Erythromycin; Female; Humans; Male; Middle Aged; Multivariate Analysis; Nitroimidazoles; Oxidoreductases, N-Demethylating; Risk; Troleandomycin; Verapamil | 2004 |
Evaluation of time-dependent cytochrome P450 inhibition using cultured human hepatocytes.
Topics: Aged; Aged, 80 and over; Cells, Cultured; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Erythromycin; Female; Fluoxetine; Hepatocytes; Humans; Male; Microsomes, Liver; Middle Aged; Ticrynafen; Troleandomycin | 2006 |
A method for selecting cis-acting regulatory sequences that respond to small molecule effectors.
Topics: 4-Butyrolactone; Amino Acid Motifs; Base Sequence; beta-Galactosidase; Chloramphenicol; Erythromycin; Gene Expression; Genes, Reporter; Molecular Sequence Data; Open Reading Frames; Peptide Library; Peptides; Protein Synthesis Inhibitors; Regulatory Sequences, Nucleic Acid; RNA, Messenger; Troleandomycin | 2010 |
Determination of time-dependent inactivation of CYP3A4 in cryopreserved human hepatocytes and assessment of human drug-drug interactions.
Topics: Cryopreservation; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Diltiazem; Drug Interactions; Enzyme Activation; Enzyme Inhibitors; Erythromycin; Hepatocytes; Humans; Microsomes, Liver; Pharmacokinetics; Risk Assessment; Time Factors; Troleandomycin; Verapamil | 2011 |