Page last updated: 2024-08-21

erythromycin and sirolimus

erythromycin has been researched along with sirolimus in 16 studies

Research

Studies (16)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	2 (12.50)	18.2507
2000's	10 (62.50)	29.6817
2010's	3 (18.75)	24.3611
2020's	1 (6.25)	2.80

Authors

Authors	Studies
Beck, WT; Schuetz, EG; Schuetz, JD	1
Li, Y; Li, YH; Wang, YH; Yang, L; Yang, SL	1
Andricopulo, AD; Moda, TL; Montanari, CA	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Cane, DE; Fu, H; Khosla, C; Lau, J	1
Dhingra, N; Kaur, H; Khanna, R; Kumari, R; Lal, R; Tuteja, D	1
Brattström, C; Burke, JT; Claesson, K	1
Hayakawa, A; Itaya, N; Kakegawa, T; Kobayashi, H; Saito, H	1
De Vos, M; Depoortere, I; Lefebvre, R; Peeters, TL; Schoonjans, R; Van Vlem, B; Vanholder, R	1
Kealey, JT	1
Akagawa, K; Omura, S; Osawa, T; Sunatsuka, T	1
Beyer, D; Bizot, MN; Jiang, Q; Kovarik, JM; Schmouder, RL; Shenouda, M	1
Akagawa, K; Omura, T; Osawa, M; Sawai, T; Sunazuka, T	1
Chasick, A; Chasik, A; Hughes, T; Leiding, JW; Salit, RB	1
Grininger, M	1

Reviews

4 review(s) available for erythromycin and sirolimus

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Regulation and manipulation of the gene clusters encoding type-I PKSs. Trends in biotechnology, 2000, Volume: 18, Issue:6 Topics: Combinatorial Chemistry Techniques; Erythromycin; Gene Expression Regulation; Genetic Engineering; Multienzyme Complexes; Multigene Family; Rifamycins; Sirolimus	2000
Creating polyketide diversity through genetic engineering. Frontiers in bioscience : a journal and virtual library, 2003, Jan-01, Volume: 8 Topics: Carbohydrate Sequence; Epothilones; Erythromycin; Molecular Structure; Multienzyme Complexes; Peptides; Protein Engineering; Ribosomal Proteins; Sirolimus	2003
Enzymology of assembly line synthesis by modular polyketide synthases. Nature chemical biology, 2023, Volume: 19, Issue:4 Topics: Anti-Bacterial Agents; Erythromycin; Polyketide Synthases; Polyketides; Sirolimus	2023

Trials

1 trial(s) available for erythromycin and sirolimus

Article	Year
Effect of multiple-dose erythromycin on everolimus pharmacokinetics. European journal of clinical pharmacology, 2005, Volume: 61, Issue:1 Topics: Adult; Anti-Bacterial Agents; Area Under Curve; Cross-Over Studies; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Erythromycin; Everolimus; Female; Half-Life; Humans; Immunosuppressive Agents; Male; Sirolimus	2005

Other Studies

11 other study(ies) available for erythromycin and sirolimus

Article	Year
Modulators and substrates of P-glycoprotein and cytochrome P4503A coordinately up-regulate these proteins in human colon carcinoma cells. Molecular pharmacology, 1996, Volume: 49, Issue:2 Topics: Adenocarcinoma; ATP Binding Cassette Transporter, Subfamily B, Member 1; Base Sequence; Blotting, Northern; Cell Line; Clotrimazole; Colonic Neoplasms; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme System; Dexamethasone; DNA Primers; Doxorubicin; Gene Expression Regulation, Neoplastic; Humans; Midazolam; Mixed Function Oxygenases; Molecular Sequence Data; Multigene Family; Phenobarbital; Phenytoin; Polymerase Chain Reaction; Rifampin; Tumor Cells, Cultured; Verapamil	1996
Modeling K(m) values using electrotopological state: substrates for cytochrome P450 3A4-mediated metabolism. Bioorganic & medicinal chemistry letters, 2005, Sep-15, Volume: 15, Issue:18 Topics: Computational Biology; Cyclohexanols; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Molecular Structure; Principal Component Analysis; Pyrrolizidine Alkaloids; Quantitative Structure-Activity Relationship; Reproducibility of Results; Substrate Specificity; Venlafaxine Hydrochloride	2005
Hologram QSAR model for the prediction of human oral bioavailability. Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24 Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2007
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Dissecting the role of acyltransferase domains of modular polyketide synthases in the choice and stereochemical fate of extender units. Biochemistry, 1999, Feb-02, Volume: 38, Issue:5 Topics: Acyl Coenzyme A; Acyltransferases; Amino Acid Sequence; Erythromycin; Escherichia coli; Isoenzymes; Molecular Sequence Data; Multienzyme Complexes; Plasmids; Protein Processing, Post-Translational; Protein Structure, Tertiary; Recombinant Fusion Proteins; Sirolimus; Stereoisomerism; Streptomyces; Substrate Specificity; Thiolester Hydrolases	1999
Sirolimus and erythromycin interaction: two cases. Transplantation proceedings, 2001, Volume: 33, Issue:3 Topics: Adult; Aged; Anti-Bacterial Agents; Erythromycin; Humans; Immunosuppressive Agents; Kidney Transplantation; Legionellosis; Male; Postoperative Complications; Sirolimus	2001
[Effect of rapamycin on cytoplasmic accumulation of hetero nuclear ribonucleoprotein C-like unwinding protein 2]. The Japanese journal of antibiotics, 2001, Volume: 54 Suppl A Topics: Animals; Anti-Bacterial Agents; Cells, Cultured; Cytoplasm; Erythromycin; Heterogeneous-Nuclear Ribonucleoproteins; Immunosuppressive Agents; Mice; NF-kappa B; Ribonucleoproteins; Roxithromycin; Sirolimus; Tacrolimus	2001
In vitro evaluation of motilin agonism by macrolide immunosuppressive drugs. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2002, Volume: 17, Issue:6 Topics: Animals; Carbachol; Cyclosporine; Duodenum; Electric Stimulation; Erythromycin; Immunosuppressive Agents; In Vitro Techniques; Kinetics; Male; Motilin; Muscle Contraction; Muscle, Smooth; Rabbits; Sirolimus; Tacrolimus	2002
[Influence of erythromycin and the metabolite, EM201 on IL-2 receptor signaling]. The Japanese journal of antibiotics, 2003, Volume: 56 Suppl A Topics: Anti-Bacterial Agents; Cell Division; Cells, Cultured; Depression, Chemical; Erythromycin; Humans; Lymphocyte Activation; Receptors, Interleukin-2; Signal Transduction; Sirolimus; T-Lymphocytes	2003
[Effect of EM201, an in vivo metabolite of erythromycin (EM), on signal transduction of IL-2 receptor]. The Japanese journal of antibiotics, 2004, Volume: 57 Suppl A Topics: Cells, Cultured; Chromones; Erythromycin; Flavonoids; Humans; Monocytes; Morpholines; Receptors, Interleukin-2; Signal Transduction; Sirolimus	2004
Successful sirolimus graded dose challenge in an erythromycin-allergic patient. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2012, Volume: 109, Issue:4 Topics: Adult; Drug Administration Schedule; Erythromycin; Feasibility Studies; Hematopoietic Stem Cell Transplantation; Human T-lymphotropic virus 1; Humans; Leukemia-Lymphoma, Adult T-Cell; Recurrence; Sirolimus	2012