Page last updated: 2024-08-21

erythromycin and ru 66647

erythromycin has been researched along with ru 66647 in 131 studies

Research

Studies (131)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	18 (13.74)	18.2507
2000's	92 (70.23)	29.6817
2010's	17 (12.98)	24.3611
2020's	4 (3.05)	2.80

Authors

Authors	Studies
Appelbaum, PC; Ednie, LM; Jacobs, MR	1
Appelbaum, PC; Jacobs, MR; Pankuch, GA; Visalli, MA	1
Barry, AL; Brown, SD; Fuchs, PC	3
Bryskier, A; Hoppe, JE	1
Citron, DM; Goldstein, EJ; Hudspeth, M; Hunt Gerardo, S; Merriam, CV	1
Bryskier, A; Lütticken, R; Reinert, RR	1
Hammerschlag, MR; Roblin, PM	1
Hamilton-Miller, JM; Shah, S	1
Eliopoulos, GM; Moellering, RC; Schülin, T; Wennersten, CB	1
Baquero, F; Portillo, A; Ruiz, F; Saenz, Y; Tenorio, C; Torres, C; Zarazaga, M	1
Agouridas, C; Denis, A	1
Douthwaite, S; Hansen, LH; Mauvais, P	2
Mankin, AS; Mauvais, P; Shah, S; Xiong, L	1
Appelbaum, PC; Credito, KL; Ednie, LM; Jacobs, MR	1
Collart-Dutilleul, V; Diu-Hercend, A; Maridonneau-Parini, I; Miossec-Bartoli, C; N'Diaye, EN; Peyron, P; Pilatre, L	1
Agouridas, C; Auger, JM; Benedetti, Y; Bonnefoy, A; Bretin, F; Chantot, JF; D'Ambrières, SG; Denis, A; Dussarat, A; Fromentin, C; Lachaud, S; Laurin, P; Le Martret, O; Loyau, V; Pejac, JM; Perron, S; Tessot, N	1
Baquero, F; Del Campo, R; Portillo, A; Ruiz-Larrea, F; Sáenz, Y; Tenorio, C; Torres, C; Zarazaga, M	1
Appelbaum, PC; Davies, TA; Jacobs, MR; Kelly, LM	1
Borlace, G; Munckhof, WJ; Turnidge, JD	1
Baltch, AL; Franke, MA; Michelsen, PB; Ritz, WJ; Smith, RP	1
Bemer-Melchior, P; Bryskier, A; Drugeon, HB; Juvin, ME; Schito, GC; Tassin, S	1
Ishii, Y; Miyazaki, S; Okamoto, H; Tateda, K; Yamaguchi, K	2
Murray, BE; Singh, KV; Zscheck, KK	1
Giovanetti, E; Marchetti, F; Montanari, MP; Varaldo, PE	1
Andrews, JM; Ashby, JP; Walker, RM; Weller, TM; Wise, R	1
Charles, PE; Chavanet, P; Desbiolles, N; Lequeu, C; Martin, L; Mateo-Ponce, V; Piroth, L; Portier, H	1
Muller-Serieys, C	1
Huovinen, P; Jalava, J; Kataja, J; Seppälä, H	1
Bryskier, A; Calvo, R; Esteban, J; Fernández-Roblas, R; Soriano, F	1
Bryskier, A	1
Bonnefoy, A; Delachaume, C; Girard, AM; Guitton, M; Le Priol, P	1
Biedenbach, DJ; Jones, RN; Rospide, MF	1
Hoban, DJ; Nichol, K; Wierzbowski, AK; Zhanel, GG	1
Brandt, CM; Bryskier, A; Holland, R; Honscha, M; Hövener, B; Lütticken, R; Reinert, RR; Truong, ND	1
Henwood, CJ; Johnson, AP; Tysall, L; Warner, M	1
Almaraz, F; Baquero, F; Cantón, R; Galán, JC; Loza, E; Morosini, MI; Negri, MC	1
Cartwright, FD; Kenny, GE	1
Su, WG; Wu, YJ	1
Appelbaum, PC; Bryskier, A; Davies, TA; Ednie, LM; Jacobs, MR; Nagai, K; Palavecino, E	1
Benjamin, WH; Crain, MC; Edwards, KM; Gray, BM; Johnson, CN; Waites, KB	1
Andrasevic, AT; Appelbaum, PC; Davies, TA; Drukalska, L; Hoellman, DB; Hryniewicz, W; Hupkova, H; Jacobs, MR; Kelly, LM; Kolman, J; Miciuleviciene, J; Nagai, K; Pana, M; Setchanova, L; Thege, MK; Trupl, J; Urbaskova, P	1
Almer, LS; Beyer, JM; Cao, Z; Doktor, SZ; Flamm, RK; Ramer, NC; Shortridge, VD; Zhong, P	1
Astfalk, N; Jagusch, H; Petridou, J; Scheuring, S; Schmitz, FJ; Schwarz, S	1
Fluit, AC; Milatovic, D; Schmitz, FJ; Schwarz, S; Verhoef, J	1
Champney, WS; Pelt, J	1
Cortes, L; Guilbault, C; Low, DE; Restieri, C; Weiss, K	1
Ma, Z; Nilius, AM	1
Astfalk, N; Köhrer, K; Petridou, J; Scheuring, S; Schmitz, FJ; Schwarz, S	1
Chuah, SK; Gollapudi, S; Iskandar, L; Thadepalli, H	1
Champney, WS	1
Shortridge, V; Zhong, P	1
Champney, WS; Tober, CL	1
Agreda, MC; Betriu, C; Culebras, E; Gómez, M; Picazo, JJ; Rodríguez-Avial, I; Sánchez, BA	1
Quinn, J; Ruoff, GE; Ziter, PS	1
Hoban, DJ; Low, DE; Nichol, KA; Palatnick, L; Zhanel, GG	1
Almaraz, F; Baquero, F; Cantón, R; del Campo, R; Loza, E; Morosini, MI	1
Chang, FY; Chuang, YC; Hsueh, PR; Huang, WK; Ko, WC; Lau, YJ; Lee, CM; Leu, HS; Liu, CY; Liu, YC; Lu, JJ; Luh, KT; Shyr, JM; Teng, LJ; Wan, JH; Wu, JJ; Wu, TL; Yan, JJ; Yang, D; Yang, YC	2
Bidet, P; Bingen, E; Brahimi, N; Deforche, D; Doit, C; Geslin, P; Loukil, C	1
Ashi-Sulaiman, A; de Azavedo, JS; Duncan, CL; Katz, KC; Low, DE; McCann, J; McGeer, AJ; Pong-Porter, S; Rzayev, Y; Sarabia, A; Willey, BM	1
Berisio, R; Fucini, P; Hansen, HA; Harms, J; Schluenzen, F; Yonath, A; Zarivach, R	1
Besier, S; Brade, V; Giesser, I; Hunfeld, KP; Schäfer, V; Wichelhaus, TA	1
Amyes, S; Walsh, F; Willcock, J	1
Chronopoulou, G; Foustoukou, M; Ioannidou, S; Kanavaki, S; Kanelopoulou, M; Pangalis, A; Papafraggas, E; Petropoulou, N; Salem, Z; Tassios, PT; Trikka-Graphakos, E; Vatopoulos, AC; Zachariadou, L	1
Appelbaum, PC; Bajaksouzian, S; Jacobs, MR	1
Aktaş, Z; Berkiten, R; Gönüllü, N; Gürol, D; Küçükbasmaci, O	1
Hisanaga, T; Hoban, DJ; Nichol, K; Wierzbowski, A; Zhanel, GG	1
Acker, G; Brade, V; Hunfeld, KP; Kraiczy, P; Rödel, R; Wichelhaus, TA	1
Crawford, SA; Jorgensen, JH; McElmeel, ML; Whitney, CG	1
Bidet, P; Bingen, E; Brahimi, N; Deforche, D; Doit, C	1
Andrews, JM; Brenwald, NP; Fraise, AP; Harnett, SJ; Jevons, G; Wise, R	1
Canales, M; Capilla, S; Cerdá Zolezzi, P; Durán, E; Gómez-Lus, R; Goñi, P; Millán, L; Rubio Calvo, MC	1
Bagel, S; Brauers, J; Henrichfreise, B; Kresken, M; Wiedemann, B	1
Bryskier, A; Chevalier, J; Chollet, R; Pagès, JM	1
Champney, WS; Mentens, N; Zurawick, K	1
Andersen, NM; Douthwaite, S; Jakobsen, L; Novotny, GW; Poehlsgaard, J	1
Appelbaum, PC; Bozdogan, B; Clark, CL; Credito, KL; Ednie, LM; Jacobs, MR; Kelly, LM; Kosowska, K; Lin, G; Matic, V; McGhee, P; Pankuch, GA; Smith, K	1
Appelbaum, PC; Clark, C; Credito, K; Dewasse, B; Hoellman, D; Jacobs, MR; Kosowska, K; Lin, G; McGhee, P; Pankuch, GA	1
Almela, M; Marco, F; Mensa, J; Ortega, M; Puig, J; Soriano, A	1
Korkhin, Y; Mankin, AS; Xiong, L	1
Abbanat, D; Bush, K; Foleno, B; Li, Y; Macielag, M; Montenegro, D; Webb, G; Wira, E	1
Canu, A; Devenyns, I; Lagrou, K; Leclercq, R; Massonet, C; Meekers, E; Syrogiannopoulos, G; Van Eldere, J; Verhaegen, J	1
Blaha, G; Moore, PB; Steitz, TA; Tu, D	1
Bosnar, M; Eraković, V; Kelnerić, Z; Munić, V; Parnham, MJ	1
Andreu, A; Gonzalez, JJ	1
Crawford, SA; Davis, KA; Fiebelkorn, KR; Jorgensen, JH	1
Dunbar, L; Fogarty, C; Kohno, S; Nusrat, R; Rangaraju, M; van Rensburg, DJ	1
Al-Lahham, A; Reinert, RR; van der Linden, M	1
Bolla, JM; Mamelli, L; Mégraud, F; Pagès, JM; Prouzet-Mauléon, V	1
Choi, SH; Choo, EJ; Jeong, JY; Kim, NJ; Kim, YS; Kwak, YG; Lee, MS; Park, SJ; Ryu, J; Woo, JH	1
De Salvo, MC; Fogarty, C; Nusrat, R; Rangaraju, M; van Rensburg, D	1
Boyd, D; Hoban, DJ; Mulvey, M; Wierzbowski, AK; Zhanel, GG	1
Abbanat, D; Bush, K; Foleno, BD; Henninger, TC; Macielag, MJ; Marinelli, BA; Zhu, B	1
Al-Lahham, A; Grivea, IN; Katopodis, GD; Reinert, RR; Syrogiannopoulos, GA	1
D'Costa, VM; Hughes, DW; McGrann, KM; Wright, GD	1
Eerola, E; Hänninen, ML; Katila, ML; Kaukoranta, SS; Koskela, M; Pajarre, S; Rautelin, H; Schönberg-Norio, D; Uksila, J	1
Crimin, K; Engtrakul, J; Fermini, B; Fossa, AA; O'Donnell, J; Wisialowski, T	1
Barker, L; Burger, MT; Chu, DT; Desai, MC; Hiebert, C; Kidney, J; Langhorne, M; Plattner, JJ; Seid, M; Shawar, R	1
Chesneau, O; Courvalin, P; Tsvetkova, K	1
Cornaglia, G; Koncan, R; Mazzariol, A; Vitali, LA	1
Choi, EC; Kim, H; Kwon, AR; Shim, MJ; Yoon, EJ; Yoon, JM	1
Ackermann, A; Bachmakov, I; Brune, K; Dörje, F; Dormann, H; Eberl, S; Fromm, MF; Gassmann, KG; Hahn, EG; König, J; Mürdter, TE; Neubert, A; Reisig, M; Renner, B; Zierhut, S	1
Janata, J; Novotná, G; Spízek, J	1
Ando, S; Inoue, M; Kishimoto, T; Ogawa, M; Sato, K; Takemura, H; Yamazaki, T	1
Allizond, V; Andreotti, S; Banche, G; Barbui, A; Carlone, NA; Cuffini, AM; Gaido, E; Li Vigni, N; Malabaila, A; Mandras, N; Roana, J; Savoia, D; Scalas, D; Tullio, V	1
Chen, XZ; Jin, ZP; Lei, PS; Li, Y; Liu, J; Liu, L; Wang, GQ; Xu, P	1
Castanheira, M; Jones, RN; Woosley, LN	1
Tang, D; Ying, L	1
Abdalla, S; El-Domany, R; El-Mahdy, TS; Mohamed, MS; Ross, JI; Snelling, AM	1
Giguère, S; Javsicas, LH; Womble, AY	1
Cate, JH; Dunkle, JA; Mankin, AS; Xiong, L	1
Blaha, G; Bulkley, D; Innis, CA; Steitz, TA	1
Akbergenov, R; Akshay, S; Bertea, M; Böttger, EC; Hobbie, SN; Oettinghaus, B; Shcherbakov, D	1
Bencetić Mihaljević, V; Letfus, V; Milić, A; Padovan, J; Ralić, J	1
Dinos, GP; Kalpaxis, DL; Krokidis, MG; Márquez, V; Wilson, DN	1
Hofmann, T; Scheuch, G; Siekmeier, R	1
Gumbart, JC; Pavlova, A	1
Gupta, P; Gupta, V; Klepacki, D; Liu, B; Mankin, AS; Schulten, K; Vázquez-Laslop, N	1
Ahn, JW; Baek, YS; Jeon, J; Song, HJ	1
Gumbart, JC; Oyelere, AK; Parks, JM; Pavlova, A	1
Baldassarri, L; Di Bonaventura, G; Gherardi, G; Monaco, M; Pantosti, A; Pimentel de Araujo, F; Pompilio, A	1
Feng, Y; Guo, Q; Shao, B	1
Min, YH	1
Pejčić, AV	1
Abdelshahid, M; Arenz, S; Beckert, B; Bock, LV; Graf, M; Grubmüller, H; Innis, CA; Leroy, EC; Mankin, AS; Seip, B; Sothiselvam, S; Svetlov, MS; Vázquez-Laslop, N; Wilson, DN	1
Chen, Z; Deng, X; Fang, Y; Hu, Y; Li, D; Ouyang, L; Xu, H; Yu, Z; Zhang, H; Zheng, J	1

Reviews

9 review(s) available for erythromycin and ru 66647

Article	Year
[Ketolides and oxazolidinones. Mechanisms of action and antibacterial spectrum]. Presse medicale (Paris, France : 1983), 2000, Dec-02, Volume: 29, Issue:37 Topics: Acetamides; Anti-Bacterial Agents; Erythromycin; Gram-Positive Bacterial Infections; Humans; Ketolides; Linezolid; Macrolides; Microbial Sensitivity Tests; Oxazolidinones; Respiratory Tract Infections; Streptococcus; Structure-Activity Relationship	2000
Ketolides-telithromycin, an example of a new class of antibacterial agents. Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases, 2000, Volume: 6, Issue:12 Topics: Anti-Bacterial Agents; Drug Resistance, Microbial; Erythromycin; Gram-Positive Cocci; Humans; Ketolides; Macrolides	2000
Recent developments on ketolides and macrolides. Current medicinal chemistry, 2001, Volume: 8, Issue:14 Topics: Animals; Anti-Bacterial Agents; Carbamates; Drug Design; Drug Evaluation, Preclinical; Erythromycin; Ketolides; Ketones; Macrolides; Structure-Activity Relationship	2001
Bacterial ribosomal subunit synthesis: a novel antibiotic target. Current drug targets. Infectious disorders, 2001, Volume: 1, Issue:1 Topics: Anti-Bacterial Agents; Anti-Infective Agents; Bacterial Proteins; Erythromycin; Ketolides; Macrolides; Protein Biosynthesis; Protein Synthesis Inhibitors; Ribosomal Proteins; Ribosomes	2001
The emerging new generation of antibiotic: ketolides. Current drug targets. Infectious disorders, 2001, Volume: 1, Issue:2 Topics: Anti-Bacterial Agents; Binding Sites; Drug Design; Erythromycin; Ketolides; Macrolides; Ribosomes; RNA, Ribosomal, 23S	2001
Ketolides: an emerging treatment for macrolide-resistant respiratory infections, focusing on S. pneumoniae. Expert opinion on emerging drugs, 2003, Volume: 8, Issue:2 Topics: Anti-Bacterial Agents; Clinical Trials as Topic; Drug Resistance, Multiple, Bacterial; Erythromycin; Humans; Ketolides; Macrolides; Respiratory Tract Infections; Streptococcus pneumoniae	2003
Recent advances in the medicinal chemistry of novel erythromycin-derivatized antibiotics. Current topics in medicinal chemistry, 2010, Volume: 10, Issue:14 Topics: Anti-Bacterial Agents; Azithromycin; Chemistry, Pharmaceutical; Clarithromycin; Drug Resistance, Microbial; Erythromycin; Humans; Ketolides; Macrolides	2010
Inhalation of macrolides: a novel approach to treatment of pulmonary infections. Advances in experimental medicine and biology, 2015, Volume: 839 Topics: Administration, Inhalation; Aerosols; Animals; Anti-Bacterial Agents; Azithromycin; Bronchiectasis; Clarithromycin; Cystic Fibrosis; Erythromycin; Humans; Ketolides; Lung; Macrolides; Pulmonary Disease, Chronic Obstructive; Rats	2015
Stevens-Johnson syndrome and toxic epidermal necrolysis associated with the use of macrolide antibiotics: a review of published cases. International journal of dermatology, 2021, Volume: 60, Issue:1 Topics: Anti-Bacterial Agents; Azithromycin; Clarithromycin; Erythromycin; Humans; Ketolides; Macrolides; Roxithromycin; Stevens-Johnson Syndrome	2021

Trials

4 trial(s) available for erythromycin and ru 66647

Article	Year
Efficacy and tolerability of 5-day, once-daily telithromycin compared with 10-day, twice-daily clarithromycin for the treatment of group A beta-hemolytic streptococcal tonsillitis/pharyngitis: a multicenter, randomized, double-blind, parallel-group study. Clinical therapeutics, 2003, Volume: 25, Issue:2 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Clarithromycin; Double-Blind Method; Drug Administration Schedule; Drug Resistance, Bacterial; Erythromycin; Female; Humans; Ketolides; Macrolides; Male; Middle Aged; Streptococcal Infections; Streptococcus pyogenes; Tonsillitis; Treatment Outcome	2003
Efficacy of telithromycin in community-acquired pneumonia caused by pneumococci with reduced susceptibility to penicillin and/or erythromycin. Chemotherapy, 2005, Volume: 51, Issue:4 Topics: Administration, Oral; Adult; Aged; Anti-Bacterial Agents; Community-Acquired Infections; Double-Blind Method; Erythromycin; Female; Humans; Ketolides; Male; Middle Aged; Penicillin Resistance; Pneumonia, Pneumococcal; Treatment Outcome	2005
Efficacy of oral telithromycin in community-acquired pneumonia caused by resistant Streptococcus pneumoniae. The Journal of infection, 2005, Volume: 51, Issue:3 Topics: Administration, Oral; Adult; Aged; Anti-Bacterial Agents; Community-Acquired Infections; Drug Resistance, Bacterial; Erythromycin; Female; Humans; Ketolides; Male; Microbial Sensitivity Tests; Middle Aged; Penicillin Resistance; Penicillins; Pneumonia, Pneumococcal; Treatment Outcome	2005
Role of p-glycoprotein inhibition for drug interactions: evidence from in vitro and pharmacoepidemiological studies. Clinical pharmacokinetics, 2007, Volume: 46, Issue:12 Topics: Aged; Aged, 80 and over; Alanine Transaminase; Aspartate Aminotransferases; ATP Binding Cassette Transporter, Subfamily B, Member 1; Bilirubin; Biological Transport; Caco-2 Cells; Creatinine; Digitoxin; Digoxin; Drug Interactions; Erythromycin; Female; Heart Diseases; Humans; Inpatients; Inulin; Ketolides; Macrolides; Male; Pharmacoepidemiology	2007

Other Studies

118 other study(ies) available for erythromycin and ru 66647

Article	Year
Comparative antianaerobic activities of the ketolides HMR 3647 (RU 66647) and HMR 3004 (RU 64004). Antimicrobial agents and chemotherapy, 1997, Volume: 41, Issue:9 Topics: Anti-Bacterial Agents; Azithromycin; Bacteria, Anaerobic; Carbon Dioxide; Clarithromycin; Erythromycin; Hydrogen-Ion Concentration; Ketolides; Macrolides; Microbial Sensitivity Tests; Roxithromycin	1997
Susceptibilities of penicillin- and erythromycin-susceptible and -resistant pneumococci to HMR 3647 (RU 66647), a new ketolide, compared with susceptibilities to 17 other agents. Antimicrobial agents and chemotherapy, 1998, Volume: 42, Issue:3 Topics: Anti-Bacterial Agents; Drug Evaluation, Preclinical; Drug Resistance, Microbial; Erythromycin; Ketolides; Macrolides; Microbial Sensitivity Tests; Penicillin Resistance; Streptococcus pneumoniae	1998
Antipneumococcal activities of a ketolide (HMR 3647), a streptogramin (quinupristin-dalfopristin), a macrolide (erythromycin), and a lincosamide (clindamycin). Antimicrobial agents and chemotherapy, 1998, Volume: 42, Issue:4 Topics: Anti-Bacterial Agents; Clindamycin; Erythromycin; Humans; Ketolides; Macrolides; Penicillin Resistance; Phenotype; Pneumococcal Infections; Streptococcus pneumoniae; Virginiamycin	1998
In vitro susceptibilities of Bordetella pertussis and Bordetella parapertussis to two ketolides (HMR 3004 and HMR 3647), four macrolides (azithromycin, clarithromycin, erythromycin A, and roxithromycin), and two ansamycins (rifampin and rifapentine). Antimicrobial agents and chemotherapy, 1998, Volume: 42, Issue:4 Topics: Anti-Bacterial Agents; Azithromycin; Bordetella; Bordetella pertussis; Clarithromycin; Erythromycin; Ketolides; Macrolides; Microbial Sensitivity Tests; Rifabutin; Rifampin; Roxithromycin	1998
Activities of HMR 3004 (RU 64004) and HMR 3647 (RU 66647) compared to those of erythromycin, azithromycin, clarithromycin, roxithromycin, and eight other antimicrobial agents against unusual aerobic and anaerobic human and animal bite pathogens isolated f Antimicrobial agents and chemotherapy, 1998, Volume: 42, Issue:5 Topics: Animals; Anti-Bacterial Agents; Azithromycin; Bacteria, Aerobic; Bacteria, Anaerobic; Bites, Human; Clarithromycin; Erythromycin; Humans; Ketolides; Macrolides; Microbial Sensitivity Tests; Roxithromycin; Skin Diseases, Bacterial; Soft Tissue Infections; Wounds and Injuries	1998
In vitro activities of the new ketolide antibiotics HMR 3004 and HMR 3647 against Streptococcus pneumoniae in Germany. Antimicrobial agents and chemotherapy, 1998, Volume: 42, Issue:6 Topics: Anti-Bacterial Agents; Drug Resistance, Multiple; Erythromycin; Germany; Humans; Ketolides; Macrolides; Microbial Sensitivity Tests; Penicillin Resistance; Streptococcus pneumoniae	1998
In vitro activity of a new ketolide antibiotic, HMR 3647, against Chlamydia pneumoniae. Antimicrobial agents and chemotherapy, 1998, Volume: 42, Issue:6 Topics: Anti-Bacterial Agents; Azithromycin; Child; Child, Preschool; Chlamydophila pneumoniae; Erythromycin; Humans; Ketolides; Macrolides; Microbial Sensitivity Tests; Roxithromycin	1998
Comparative in-vitro activity of ketolide HMR 3647 and four macrolides against gram-positive cocci of known erythromycin susceptibility status. The Journal of antimicrobial chemotherapy, 1998, Volume: 41, Issue:6 Topics: Anti-Bacterial Agents; Drug Resistance, Microbial; Erythromycin; Gram-Positive Cocci; Ketolides; Macrolides; Microbial Sensitivity Tests	1998
In-vitro activity of the new ketolide antibiotic HMR 3647 against gram-positive bacteria. The Journal of antimicrobial chemotherapy, 1998, Volume: 42, Issue:3 Topics: Anti-Bacterial Agents; Drug Resistance, Microbial; Drug Resistance, Multiple; Erythromycin; Gram-Positive Bacteria; Humans; Ketolides; Macrolides; Microbial Sensitivity Tests	1998
In vitro activity of the new ketolide HMR3647 in comparison with those of macrolides and pristinamycins against Enterococcus spp. Antimicrobial agents and chemotherapy, 1998, Volume: 42, Issue:12 Topics: Anti-Bacterial Agents; Drug Resistance, Microbial; Enterococcus; Erythromycin; Ketolides; Macrolides; Microbial Sensitivity Tests; Phenotype; Virginiamycin	1998
Synthesis of 6-O-methyl-azithromycin and its ketolide analogue via Beckmann rearrangement of 9(E)-6-O-methyl-erythromycin oxime. Bioorganic & medicinal chemistry letters, 1998, Sep-22, Volume: 8, Issue:18 Topics: Anti-Bacterial Agents; Azithromycin; Erythromycin; Escherichia coli; Haemophilus influenzae; Ketolides; Macrolides; Microbial Sensitivity Tests; Models, Molecular; Staphylococcus aureus; Streptococcus; Structure-Activity Relationship	1998
The macrolide-ketolide antibiotic binding site is formed by structures in domains II and V of 23S ribosomal RNA. Molecular microbiology, 1999, Volume: 31, Issue:2 Topics: Anti-Bacterial Agents; Base Sequence; Binding Sites; Cell Division; Erythromycin; Escherichia coli; Ketolides; Macrolides; Molecular Sequence Data; Nucleic Acid Conformation; RNA, Ribosomal, 23S	1999
A ketolide resistance mutation in domain II of 23S rRNA reveals the proximity of hairpin 35 to the peptidyl transferase centre. Molecular microbiology, 1999, Volume: 31, Issue:2 Topics: Anti-Bacterial Agents; Base Sequence; Binding Sites; Drug Resistance, Microbial; Erythromycin; Escherichia coli; Ketolides; Macrolides; Molecular Sequence Data; Mutation; Nucleic Acid Conformation; Peptidyl Transferases; Ribosomes; RNA, Ribosomal, 23S	1999
Activity of telithromycin (HMR 3647) against anaerobic bacteria compared to those of eight other agents by time-kill methodology. Antimicrobial agents and chemotherapy, 1999, Volume: 43, Issue:8 Topics: Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Azithromycin; Bacteria, Anaerobic; beta-Lactamases; Clarithromycin; Clindamycin; Drug Therapy, Combination; Erythromycin; Gram-Negative Anaerobic Bacteria; Gram-Positive Bacteria; Ketolides; Macrolides; Metronidazole; Microbial Sensitivity Tests; Roxithromycin; Virginiamycin	1999
The new ketolide HMR3647 accumulates in the azurophil granules of human polymorphonuclear cells. Antimicrobial agents and chemotherapy, 1999, Volume: 43, Issue:10 Topics: Anti-Bacterial Agents; Cell Line; Centrifugation; Cytoplasmic Granules; Erythromycin; Humans; Ketolides; Leukocytes, Mononuclear; Macrolides; Neutrophils; Subcellular Fractions	1999
Synthesis and antibacterial activity of HMR 3647 a new ketolide highly potent against erythromycin-resistant and susceptible pathogens. Bioorganic & medicinal chemistry letters, 1999, Nov-01, Volume: 9, Issue:21 Topics: Animals; Anti-Bacterial Agents; Drug Resistance, Microbial; Erythromycin; Gram-Negative Bacteria; Gram-Positive Bacteria; Haemophilus influenzae; Ketolides; Macrolides; Mice; Microbial Sensitivity Tests; Molecular Structure	1999
In vitro activities of ketolide HMR3647, macrolides, and other antibiotics against Lactobacillus, Leuconostoc, and Pediococcus isolates. Antimicrobial agents and chemotherapy, 1999, Volume: 43, Issue:12 Topics: Anti-Bacterial Agents; Anti-Infective Agents; Ciprofloxacin; Erythromycin; Ketolides; Lactobacillus; Leuconostoc; Macrolides; Microbial Sensitivity Tests; Pediococcus	1999
Antipneumococcal activity of telithromycin by agar dilution, microdilution, E test, and disk diffusion methodologies. Journal of clinical microbiology, 2000, Volume: 38, Issue:4 Topics: Anti-Bacterial Agents; Colony Count, Microbial; Drug Resistance, Microbial; Erythromycin; Humans; Ketolides; Macrolides; Microbial Sensitivity Tests; Pneumococcal Infections; Streptococcus pneumoniae	2000
Macrolide-ketolide inhibition of MLS-resistant ribosomes is improved by alternative drug interaction with domain II of 23S rRNA. Molecular microbiology, 2000, Volume: 36, Issue:1 Topics: Anti-Bacterial Agents; Base Sequence; Binding Sites; Clarithromycin; Drug Interactions; Drug Resistance, Microbial; Erythromycin; Escherichia coli; Ketolides; Macrolides; Microbial Sensitivity Tests; Molecular Sequence Data; Mutation; Protein Synthesis Inhibitors; Ribosomes; RNA, Ribosomal, 23S	2000
Postantibiotic suppression of growth of erythromycin A-susceptible and -resistant gram-positive bacteria by the ketolides telithromycin (HMR 3647) and HMR 3004. Antimicrobial agents and chemotherapy, 2000, Volume: 44, Issue:6 Topics: Anti-Bacterial Agents; Drug Resistance, Microbial; Erythromycin; Ketolides; Macrolides; Staphylococcus; Streptococcus	2000
Antibacterial effect of telithromycin (HMR 3647) and comparative antibiotics against intracellular Legionella pneumophila. The Journal of antimicrobial chemotherapy, 2000, Volume: 46, Issue:1 Topics: Anti-Bacterial Agents; Erythromycin; Humans; Ketolides; Legionella pneumophila; Legionnaires' Disease; Levofloxacin; Macrolides; Monocytes; Ofloxacin	2000
In vitro activity of the new ketolide telithromycin compared with those of macrolides against Streptococcus pyogenes: influences of resistance mechanisms and methodological factors. Antimicrobial agents and chemotherapy, 2000, Volume: 44, Issue:11 Topics: Anti-Bacterial Agents; Bacterial Proteins; Carbon Dioxide; Culture Media; Drug Resistance, Microbial; Erythromycin; Humans; Ketolides; Macrolides; Membrane Proteins; Methyltransferases; Microbial Sensitivity Tests; Polymerase Chain Reaction; Streptococcus pyogenes	2000
Comparative in vitro activity of telithromycin (HMR 3647), three macrolides, amoxycillin, cefdinir and levofloxacin against gram-positive clinical isolates in Japan. The Journal of antimicrobial chemotherapy, 2000, Volume: 46, Issue:5 Topics: Amoxicillin; Anti-Bacterial Agents; Cefdinir; Cephalosporins; Community-Acquired Infections; Drug Resistance, Microbial; Erythromycin; Gram-Positive Bacteria; Humans; Japan; Ketolides; Levofloxacin; Macrolides; Microbial Sensitivity Tests; Ofloxacin; Penicillins; Respiratory Tract Infections; Staphylococcus aureus	2000
Efficacy of telithromycin (HMR 3647) against enterococci in a mouse peritonitis model. Antimicrobial agents and chemotherapy, 2000, Volume: 44, Issue:12 Topics: Animals; Anti-Bacterial Agents; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Resistance, Microbial; Enterococcus; Erythromycin; Ketolides; Macrolides; Mice; Microbial Sensitivity Tests; Peritonitis	2000
In vitro activity of ketolides telithromycin and HMR 3004 against italian isolates of Streptococcus pyogenes and Streptococcus pneumoniae with different erythromycin susceptibility. The Journal of antimicrobial chemotherapy, 2000, Volume: 46, Issue:6 Topics: Anti-Bacterial Agents; Drug Resistance, Microbial; Erythromycin; Ketolides; Macrolides; Microbial Sensitivity Tests; Streptococcus pneumoniae; Streptococcus pyogenes	2000
The in vitro activity of ABT773, a new ketolide antimicrobial agent. The Journal of antimicrobial chemotherapy, 2000, Volume: 46, Issue:6 Topics: Anti-Bacterial Agents; Erythromycin; Humans; Ketolides; Macrolides; Methicillin Resistance; Microbial Sensitivity Tests	2000
HMR 3647 human-like treatment of experimental pneumonia due to penicillin-resistant and erythromycin-resistant Streptococcus pneumoniae. The Journal of antimicrobial chemotherapy, 2001, Volume: 47, Issue:1 Topics: Amoxicillin; Animals; Anti-Bacterial Agents; Disease Models, Animal; Erythromycin; Humans; Ketolides; Macrolides; Male; Penicillins; Pneumonia, Pneumococcal; Rabbits; Streptococcus pneumoniae; Treatment Outcome	2001
In vitro activities of the novel ketolide telithromycin (HMR 3647) against erythromycin-resistant Streptococcus species. Antimicrobial agents and chemotherapy, 2001, Volume: 45, Issue:3 Topics: Anti-Bacterial Agents; Drug Resistance, Microbial; Erythromycin; Humans; Ketolides; Macrolides; Microbial Sensitivity Tests; Phenotype; Streptococcus	2001
The bactericidal activities of HMR 3004, HMR 3647 and erythromycin against gram-positive bacilli and development of resistance. The Journal of antimicrobial chemotherapy, 1999, Volume: 43, Issue:2 Topics: Animals; Anti-Bacterial Agents; Corynebacterium; Drug Resistance, Microbial; Erythromycin; Gram-Positive Bacteria; Ketolides; Macrolides; Microbial Sensitivity Tests; Mutation; Serum Bactericidal Test	1999
In vivo efficacy of the new ketolide telithromycin (HMR 3647) in murine infection models. Antimicrobial agents and chemotherapy, 2001, Volume: 45, Issue:6 Topics: Administration, Oral; Animals; Anti-Bacterial Agents; Area Under Curve; Bacterial Infections; Biological Availability; Erythromycin; Half-Life; Injections, Intravenous; Ketolides; Macrolides; Male; Mice; Microbial Sensitivity Tests; Virginiamycin	2001
Comparative antimicrobial activity of ABT-773, a novel ketolide, tested against drug-resistant Gram-positive cocci and Haemophilus influenzae. International journal of antimicrobial agents, 2001, Volume: 17, Issue:6 Topics: Anti-Bacterial Agents; Drug Resistance, Microbial; Enterococcus; Erythromycin; Gram-Positive Cocci; Haemophilus influenzae; Humans; Ketolides; Macrolides; Staphylococcus; Staphylococcus aureus; Streptococcus; Streptococcus pneumoniae	2001
Macrolide-resistant Streptococcus pneumoniae in Canada during 1998-1999: prevalence of mef(A) and erm(B) and susceptibilities to ketolides. Antimicrobial agents and chemotherapy, 2001, Volume: 45, Issue:7 Topics: Anti-Bacterial Agents; Bacterial Proteins; Canada; Drug Resistance, Microbial; Erythromycin; Gene Frequency; Humans; Ketolides; Macrolides; Membrane Proteins; Methyltransferases; Microbial Sensitivity Tests; Streptococcus pneumoniae	2001
Macrolide resistance in Streptococcus pyogenes isolates from throat infections in the region of Aachen, Germany. Microbial drug resistance (Larchmont, N.Y.), 2001,Summer, Volume: 7, Issue:2 Topics: Anti-Bacterial Agents; Drug Resistance; Erythromycin; Genotype; Germany; Ketolides; Macrolides; Microbial Sensitivity Tests; Pharynx; Phenotype; Polymorphism, Restriction Fragment Length; Regulon; Respiratory Tract Infections; Reverse Transcriptase Polymerase Chain Reaction; Streptococcal Infections; Streptococcus pyogenes; Streptogramins; Virginiamycin	2001
Activity of the ketolide telithromycin (HMR-3647) against erythromycin-susceptible and -resistant pneumococci isolated in the UK. International journal of antimicrobial agents, 2001, Volume: 18, Issue:1 Topics: Anti-Bacterial Agents; Bacterial Proteins; Clindamycin; Drug Resistance, Microbial; Drug Resistance, Multiple; Erythromycin; Ketolides; Macrolides; Membrane Proteins; Methyltransferases; Streptococcus pneumoniae	2001
In vitro activity of telithromycin against Spanish Streptococcus pneumoniae isolates with characterized macrolide resistance mechanisms. Antimicrobial agents and chemotherapy, 2001, Volume: 45, Issue:9 Topics: Anti-Bacterial Agents; Clindamycin; Drug Resistance, Microbial; Erythromycin; Humans; Ketolides; Macrolides; Microbial Sensitivity Tests; Spain; Streptococcus pneumoniae; Virginiamycin	2001
Susceptibilities of Mycoplasma hominis, M. pneumoniae, and Ureaplasma urealyticum to GAR-936, dalfopristin, dirithromycin, evernimicin, gatifloxacin, linezolid, moxifloxacin, quinupristin-dalfopristin, and telithromycin compared to their susceptibilities Antimicrobial agents and chemotherapy, 2001, Volume: 45, Issue:9 Topics: 4-Quinolones; Acetamides; Aminoglycosides; Anti-Bacterial Agents; Aza Compounds; Erythromycin; Fluoroquinolones; Gatifloxacin; Humans; Hydrogen-Ion Concentration; Ketolides; Linezolid; Macrolides; Microbial Sensitivity Tests; Minocycline; Moxifloxacin; Mycoplasma hominis; Mycoplasma pneumoniae; Oxazolidinones; Quinolines; Tetracyclines; Tigecycline; Ureaplasma urealyticum; Virginiamycin	2001
Relative potency of telithromycin, azithromycin and erythromycin against recent clinical isolates of gram-positive cocci. European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2001, Volume: 20, Issue:7 Topics: Anti-Bacterial Agents; Azithromycin; Drug Resistance, Microbial; Erythromycin; Gram-Positive Cocci; Humans; Ketolides; Macrolides; Microbial Sensitivity Tests; Probability; Sensitivity and Specificity	2001
Activities of a new fluoroketolide, HMR 3787, and its (des)-fluor derivative RU 64399 compared to those of telithromycin, erythromycin A, azithromycin, clarithromycin, and clindamycin against macrolide-susceptible or -resistant Streptococcus pneumoniae an Antimicrobial agents and chemotherapy, 2001, Volume: 45, Issue:11 Topics: Anti-Bacterial Agents; Azithromycin; Clarithromycin; Clindamycin; Drug Resistance; Erythromycin; Ketolides; Macrolides; Microbial Sensitivity Tests; Streptococcus pneumoniae; Streptococcus pyogenes	2001
In vivo efficacy of telithromycin (HMR3647) against Streptococcus pneumoniae and Haemophilus influenzae. Antimicrobial agents and chemotherapy, 2001, Volume: 45, Issue:11 Topics: Animals; Anti-Bacterial Agents; Drug Resistance; Erythromycin; Haemophilus Infections; Haemophilus influenzae; Half-Life; Ketolides; Macrolides; Male; Mice; Mice, Inbred CBA; Mice, Inbred ICR; Microbial Sensitivity Tests; Pneumococcal Infections; Respiratory Tract Infections; Streptococcus pneumoniae	2001
In vitro activity of ABT-773, telithromycin and eight other antimicrobials against erythromycin-resistant Streptococcus pneumoniae respiratory isolates of children. International journal of antimicrobial agents, 2001, Volume: 18, Issue:6 Topics: Anti-Bacterial Agents; Anti-Infective Agents; Child; Dose-Response Relationship, Drug; Drug Resistance; Drug Resistance, Multiple, Bacterial; Erythromycin; Fluoroquinolones; Humans; Ketolides; Macrolides; Microbial Sensitivity Tests; Streptococcus pneumoniae	2001
Selection of zone size interpretive criteria for disk diffusion susceptibility tests of three antibiotics against Streptococcus pneumoniae, using the New Guidelines of the National Committee for Clinical Laboratory Standards. Antimicrobial agents and chemotherapy, 2002, Volume: 46, Issue:2 Topics: Anti-Bacterial Agents; Cefotaxime; Ceftriaxone; Clinical Laboratory Techniques; Diffusion; Erythromycin; Guidelines as Topic; Humans; Ketolides; Macrolides; Microbial Sensitivity Tests; Streptococcus pneumoniae	2002
Susceptibility to telithromycin in 1,011 Streptococcus pyogenes isolates from 10 central and Eastern European countries. Antimicrobial agents and chemotherapy, 2002, Volume: 46, Issue:2 Topics: Anti-Bacterial Agents; Azithromycin; Drug Resistance, Bacterial; Erythromycin; Europe, Eastern; Genes, Bacterial; Humans; Ketolides; Macrolides; Microbial Sensitivity Tests; Streptococcus pyogenes	2002
Comparison of in vitro activities of ABT-773 and telithromycin against macrolide-susceptible and -resistant streptococci and staphylococci. Antimicrobial agents and chemotherapy, 2002, Volume: 46, Issue:3 Topics: Anti-Bacterial Agents; Drug Resistance, Microbial; Erythromycin; Humans; Ketolides; Macrolides; Microbial Sensitivity Tests; Respiratory Tract Infections; Ribosomes; Staphylococcus; Streptococcus	2002
Molecular characterization of ketolide-resistant erm(A)-carrying Staphylococcus aureus isolates selected in vitro by telithromycin, ABT-773, quinupristin and clindamycin. The Journal of antimicrobial chemotherapy, 2002, Volume: 49, Issue:4 Topics: Anti-Bacterial Agents; Bacterial Proteins; Clindamycin; DNA Transposable Elements; Drug Resistance, Bacterial; Erythromycin; Ketolides; Macrolides; Methyltransferases; Mutation; Staphylococcus aureus; Virginiamycin	2002
In vitro activities of the ketolides ABT-773 and telithromycin and of three macrolides against genetically characterized isolates of Streptococcus pneumoniae, Streptococcus pyogenes, Haemophilus influenzae and Moraxella catarrhalis. The Journal of antimicrobial chemotherapy, 2002, Volume: 50, Issue:1 Topics: Anti-Bacterial Agents; Community-Acquired Infections; Drug Resistance, Bacterial; Erythromycin; Genes, Bacterial; Haemophilus influenzae; Humans; Ketolides; Macrolides; Microbial Sensitivity Tests; Moraxella catarrhalis; Respiratory Tract Infections; Streptococcus	2002
The ketolide antibiotic ABT-773 is a specific inhibitor of translation and 50S ribosomal subunit formation in Streptococcus pneumoniae cells. Current microbiology, 2002, Volume: 45, Issue:3 Topics: Anti-Bacterial Agents; Erythromycin; Humans; In Vitro Techniques; Ketolides; Macrolides; Pneumococcal Infections; Protein Biosynthesis; Ribosomes; Staphylococcus aureus; Streptococcus pneumoniae	2002
Genotypic characterization of macrolide-resistant strains of Streptococcus pneumoniae isolated in Quebec, Canada, and in vitro activity of ABT-773 and telithromycin. The Journal of antimicrobial chemotherapy, 2002, Volume: 50, Issue:3 Topics: Adolescent; Adult; Anti-Bacterial Agents; Child; Drug Resistance, Bacterial; Erythromycin; Female; Genes, Bacterial; Genotype; Humans; Ketolides; Macrolides; Male; Microbial Sensitivity Tests; Pneumococcal Infections; Quebec; Streptococcus pneumoniae	2002
Ketolides: the future of the macrolides? Current opinion in pharmacology, 2002, Volume: 2, Issue:5 Topics: Anti-Bacterial Agents; Bacteria; Bacterial Infections; Bacterial Proteins; Drug Resistance, Microbial; Erythromycin; Humans; Ketolides; Macrolides; Methyltransferases; Ribosomes	2002
Molecular analysis of constitutively expressed erm(C) genes selected in vitro by incubation in the presence of the noninducers quinupristin, telithromycin, or ABT-773. Microbial drug resistance (Larchmont, N.Y.), 2002,Fall, Volume: 8, Issue:3 Topics: Anti-Bacterial Agents; Drug Resistance, Microbial; Erythromycin; Genes, Bacterial; In Vitro Techniques; Ketolides; Macrolides; Microbial Sensitivity Tests; Mutation; Protein Biosynthesis; Selection, Genetic; Staphylococcus aureus; Virginiamycin	2002
Comparison of telithromycin, a new ketolide, with erythromycin and clarithromycin for the treatment of Haemophilus influenzae pneumonia in suckling, middle aged and senescent mice. International journal of antimicrobial agents, 2002, Volume: 20, Issue:3 Topics: Aging; Animals; Animals, Suckling; Anti-Bacterial Agents; Area Under Curve; Clarithromycin; Drug Administration Schedule; Drug Evaluation, Preclinical; Erythromycin; Haemophilus influenzae; Ketolides; Lung; Macrolides; Mice; Pneumonia, Bacterial; Tissue Distribution	2002
Preferential inhibition of protein synthesis by ketolide antibiotics in Haemophilus influenzae cells. Current microbiology, 2003, Volume: 46, Issue:2 Topics: Anti-Bacterial Agents; Bacterial Proteins; Erythromycin; Haemophilus influenzae; Humans; Inhibitory Concentration 50; Ketolides; Macrolides; Microbial Sensitivity Tests; Protein Synthesis Inhibitors; Ribosomes	2003
Erythromycin and clindamycin resistance and telithromycin susceptibility in Streptococcus agalactiae. Antimicrobial agents and chemotherapy, 2003, Volume: 47, Issue:3 Topics: Anti-Bacterial Agents; Clindamycin; Cross Infection; Drug Resistance, Bacterial; Erythromycin; Humans; Infant, Newborn; Ketolides; Macrolides; Microbial Sensitivity Tests; Spain; Streptococcal Infections; Streptococcus agalactiae; Tetracycline Resistance	2003
Antimicrobial resistance in Haemophilus influenzae and Moraxella catarrhalis respiratory tract isolates: results of the Canadian Respiratory Organism Susceptibility Study, 1997 to 2002. Antimicrobial agents and chemotherapy, 2003, Volume: 47, Issue:6 Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; beta-Lactam Resistance; beta-Lactamases; Canada; Drug Resistance, Multiple, Bacterial; Erythromycin; Female; Gram-Negative Bacterial Infections; Haemophilus influenzae; Humans; Influenza, Human; Ketolides; Longitudinal Studies; Macrolides; Male; Microbial Sensitivity Tests; Middle Aged; Minocycline; Moraxella catarrhalis; Respiratory Tract Infections; Tigecycline	2003
Streptococcus pyogenes isolates with characterized macrolide resistance mechanisms in Spain: in vitro activities of telithromycin and cethromycin. The Journal of antimicrobial chemotherapy, 2003, Volume: 52, Issue:1 Topics: Anti-Bacterial Agents; Drug Resistance; Erythromycin; Genes, Bacterial; Humans; Ketolides; Macrolides; Microbial Sensitivity Tests; Phenotype; Reverse Transcriptase Polymerase Chain Reaction; Spain; Streptococcal Infections; Streptococcus pyogenes	2003
Telithromycin- and fluoroquinolone-resistant Streptococcus pneumoniae in Taiwan with high prevalence of resistance to macrolides and beta-lactams: SMART program 2001 data. Antimicrobial agents and chemotherapy, 2003, Volume: 47, Issue:7 Topics: Adult; Anti-Bacterial Agents; Anti-Infective Agents; beta-Lactam Resistance; Ciprofloxacin; Erythromycin; Genotype; Humans; Incidence; Ketolides; Macrolides; Microbial Sensitivity Tests; Penicillin Resistance; Penicillins; Pneumococcal Infections; Prevalence; Streptococcus pneumoniae; Taiwan	2003
Telithromycin and quinupristin-dalfopristin resistance in clinical isolates of Streptococcus pyogenes: SMART Program 2001 Data. Antimicrobial agents and chemotherapy, 2003, Volume: 47, Issue:7 Topics: Anti-Bacterial Agents; Drug Resistance, Bacterial; Erythromycin; Genes, Bacterial; Humans; Ketolides; Macrolides; Microbial Sensitivity Tests; Phenotype; Streptococcal Infections; Streptococcus pyogenes; Taiwan; Virginiamycin	2003
Activity of telithromycin against penicillin-resistant Streptococcus pneumoniae isolates recovered from French children with invasive and noninvasive infections. Antimicrobial agents and chemotherapy, 2003, Volume: 47, Issue:7 Topics: Amoxicillin; Anti-Bacterial Agents; Azithromycin; Cefpodoxime; Ceftizoxime; Ceftriaxone; Child; Drug Resistance, Bacterial; Erythromycin; France; Humans; In Vitro Techniques; Josamycin; Ketolides; Macrolides; Penicillin G; Penicillin Resistance; Penicillins; Pneumococcal Infections; Streptococcus pneumoniae	2003
Emergence of macrolide resistance in throat culture isolates of group a streptococci in Ontario, Canada, in 2001. Antimicrobial agents and chemotherapy, 2003, Volume: 47, Issue:7 Topics: Anti-Bacterial Agents; Clindamycin; Drug Resistance, Bacterial; Erythromycin; Humans; Ketolides; Macrolides; Microbial Sensitivity Tests; Ontario; Pharynx; Prevalence; Streptococcal Infections; Streptococcus pyogenes	2003
Structural insight into the antibiotic action of telithromycin against resistant mutants. Journal of bacteriology, 2003, Volume: 185, Issue:14 Topics: Anti-Bacterial Agents; Binding Sites; Crystallization; Crystallography, X-Ray; Deinococcus; Drug Resistance, Bacterial; Erythromycin; Humans; Ketolides; Macrolides; Models, Molecular; Molecular Sequence Data; RNA, Ribosomal, 23S	2003
Selection of ketolide resistance in Staphylococcus aureus. International journal of antimicrobial agents, 2003, Volume: 22, Issue:1 Topics: Anti-Bacterial Agents; Drug Resistance, Bacterial; Erythromycin; Genes, Bacterial; Humans; In Vitro Techniques; Ketolides; Macrolides; Mutation; Selection, Genetic; Staphylococcal Infections; Staphylococcus aureus	2003
High-level telithromycin resistance in laboratory-generated mutants of Streptococcus pneumoniae. The Journal of antimicrobial chemotherapy, 2003, Volume: 52, Issue:3 Topics: Amino Acid Sequence; Anti-Bacterial Agents; Bacterial Proteins; Base Sequence; Clarithromycin; DNA Primers; Drug Resistance, Bacterial; Erythromycin; Ketolides; Macrolides; Membrane Proteins; Methyltransferases; Microbial Sensitivity Tests; Molecular Sequence Data; Mutation; Reverse Transcriptase Polymerase Chain Reaction; Ribosomes; Streptococcus pneumoniae	2003
In vitro activity of telithromycin (HMR 3647) against Greek Streptococcus pyogenes and Streptococcus pneumoniae clinical isolates with different macrolide susceptibilities. Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases, 2003, Volume: 9, Issue:7 Topics: Anti-Bacterial Agents; Clarithromycin; Dose-Response Relationship, Drug; Drug Resistance, Bacterial; Erythromycin; Greece; Ketolides; Macrolides; Streptococcus pneumoniae; Streptococcus pyogenes	2003
Telithromycin post-antibiotic and post-antibiotic sub-MIC effects for 10 Gram-positive cocci. The Journal of antimicrobial chemotherapy, 2003, Volume: 52, Issue:5 Topics: Anti-Bacterial Agents; Bacterial Proteins; Clindamycin; Colony Count, Microbial; Drug Resistance, Bacterial; Erythromycin; Gram-Positive Cocci; Humans; Ketolides; Macrolides; Microbial Sensitivity Tests; Staphylococcus; Streptococcus	2003
In vitro activity of telithromycin compared with macrolides and fluoroquinolones against Streptococcus pneumoniae, Haemophilus influenzae and Moraxella catarrhalis. International journal of antimicrobial agents, 2003, Volume: 22, Issue:5 Topics: Anti-Bacterial Agents; Erythromycin; Fluoroquinolones; Haemophilus influenzae; Humans; In Vitro Techniques; Ketolides; Macrolides; Microbial Sensitivity Tests; Moraxella catarrhalis; Streptococcus pneumoniae	2003
Comparison of in vitro activities of ketolides, macrolides, and an azalide against the spirochete Borrelia burgdorferi. Antimicrobial agents and chemotherapy, 2004, Volume: 48, Issue:1 Topics: Anti-Bacterial Agents; Anti-Infective Agents; Aza Compounds; Borrelia burgdorferi; Erythromycin; Humans; Ketolides; Lyme Disease; Macrolides; Microbial Sensitivity Tests	2004
Activities of cethromycin and telithromycin against recent North American isolates of Streptococcus pneumoniae. Antimicrobial agents and chemotherapy, 2004, Volume: 48, Issue:2 Topics: Anti-Bacterial Agents; Drug Resistance, Bacterial; Erythromycin; Genes, Bacterial; Humans; Ketolides; Macrolides; Microbial Sensitivity Tests; North America; Pneumococcal Infections; Reverse Transcriptase Polymerase Chain Reaction; Streptococcus pneumoniae	2004
Telithromycin susceptibility and genomic diversity of macrolide-resistant serotype III group B streptococci isolated in perinatal infections. Antimicrobial agents and chemotherapy, 2004, Volume: 48, Issue:2 Topics: Anti-Bacterial Agents; Bacterial Proteins; Drug Resistance, Bacterial; Erythromycin; Female; Genes, Bacterial; Humans; Infant, Newborn; Ketolides; Macrolides; Membrane Proteins; Methyltransferases; Microbial Sensitivity Tests; Pregnancy; Reverse Transcriptase Polymerase Chain Reaction; Streptococcal Infections; Streptococcus agalactiae	2004
Comparative study of the in vitro activity of a new fluoroquinolone, ABT-492. The Journal of antimicrobial chemotherapy, 2004, Volume: 53, Issue:5 Topics: Anti-Bacterial Agents; Anti-Infective Agents; Bacteria; Bacterial Infections; Chlamydia trachomatis; Chlamydophila pneumoniae; Ciprofloxacin; Erythromycin; Fluoroquinolones; Humans; Ketolides; Macrolides; Microbial Sensitivity Tests; Quinolones	2004
Macrolide resistance phenotypes of commensal viridans group streptococci and Gemella spp. and PCR detection of resistance genes. International journal of antimicrobial agents, 2004, Volume: 23, Issue:6 Topics: Acetamides; Anti-Bacterial Agents; Bacterial Proteins; Drug Resistance; Erythromycin; Genes, Bacterial; Humans; Ketolides; Lincosamides; Linezolid; Macrolides; Membrane Proteins; Methyltransferases; Microbial Sensitivity Tests; Oxazolidinones; Staphylococcaceae; Streptogramin B; Tetracycline Resistance; Virginiamycin; Viridans Streptococci	2004
High prevalence of the ermB gene among erythromycin-resistant streptococcus pneumoniae isolates in Germany during the winter of 2000-2001 and in vitro activity of telithromycin. Antimicrobial agents and chemotherapy, 2004, Volume: 48, Issue:8 Topics: Anti-Bacterial Agents; Bacterial Proteins; Drug Resistance, Bacterial; Electrophoresis, Gel, Pulsed-Field; Erythromycin; Genotype; Germany; Ketolides; Macrolides; Membrane Proteins; Methyltransferases; Pneumococcal Infections; Reverse Transcriptase Polymerase Chain Reaction; Streptococcus pneumoniae	2004
The AcrAB-TolC pump is involved in macrolide resistance but not in telithromycin efflux in Enterobacter aerogenes and Escherichia coli. Antimicrobial agents and chemotherapy, 2004, Volume: 48, Issue:9 Topics: Anti-Bacterial Agents; Arginine; Bacterial Outer Membrane Proteins; Dose-Response Relationship, Drug; Drug Resistance, Bacterial; Enterobacter aerogenes; Erythromycin; Escherichia coli; Escherichia coli Proteins; Ketolides; Macrolides; Membrane Transport Proteins; Microbial Sensitivity Tests	2004
An examination of the differential sensitivity to ketolide antibiotics in ermB strains of Streptococcus pyogenes and Streptococcus pneumoniae. Current microbiology, 2004, Volume: 49, Issue:4 Topics: Anti-Bacterial Agents; Bacterial Proteins; Drug Resistance, Bacterial; Erythromycin; Ketolides; Macrolides; Methyltransferases; Microbial Sensitivity Tests; Streptococcus pneumoniae; Streptococcus pyogenes	2004
Ketolide antimicrobial activity persists after disruption of interactions with domain II of 23S rRNA. Antimicrobial agents and chemotherapy, 2004, Volume: 48, Issue:10 Topics: Anti-Bacterial Agents; Erythromycin; Escherichia coli; Ketolides; Microbial Sensitivity Tests; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Plasmids; RNA, Ribosomal, 23S; Tylosin	2004
Antipneumococcal activities of two novel macrolides, GW 773546 and GW 708408, compared with those of erythromycin, azithromycin, clarithromycin, clindamycin, and telithromycin. Antimicrobial agents and chemotherapy, 2004, Volume: 48, Issue:11 Topics: Anti-Bacterial Agents; Azithromycin; Clarithromycin; Clindamycin; Drug Resistance, Bacterial; Erythromycin; Genes, Bacterial; Ketolides; Macrolides; Microbial Sensitivity Tests; Mutation; Streptococcus pneumoniae; Time Factors	2004
Activities of two novel macrolides, GW 773546 and GW 708408, compared with those of telithromycin, erythromycin, azithromycin, and clarithromycin against Haemophilus influenzae. Antimicrobial agents and chemotherapy, 2004, Volume: 48, Issue:11 Topics: Anti-Bacterial Agents; Azithromycin; Clarithromycin; Drug Resistance, Bacterial; Erythromycin; Haemophilus influenzae; Ketolides; Macrolides; Microbial Sensitivity Tests; Ribosomal Proteins; RNA, Ribosomal, 23S; Time Factors	2004
Activity of telithromycin against erythromycin-susceptible and -resistant Streptococcus pneumoniae isolates from adults with invasive infections. International journal of antimicrobial agents, 2004, Volume: 24, Issue:6 Topics: Adult; Drug Resistance, Bacterial; Erythromycin; Humans; Ketolides; Microbial Sensitivity Tests; Pneumococcal Infections; Streptococcus pneumoniae	2004
Binding site of the bridged macrolides in the Escherichia coli ribosome. Antimicrobial agents and chemotherapy, 2005, Volume: 49, Issue:1 Topics: Anti-Bacterial Agents; Base Sequence; Binding Sites; Binding, Competitive; Drug Resistance, Bacterial; Erythromycin; Escherichia coli; Ketolides; Macrolides; Microbial Sensitivity Tests; Molecular Sequence Data; Mutation; Ribosomes; RNA, Ribosomal, 23S	2005
In vitro activities of novel 2-fluoro-naphthyridine-containing ketolides. Antimicrobial agents and chemotherapy, 2005, Volume: 49, Issue:1 Topics: Anti-Bacterial Agents; Bacteria; Colony Count, Microbial; Drug Resistance, Bacterial; Erythromycin; Haemophilus influenzae; Humans; Ketolides; Microbial Sensitivity Tests; Moraxella catarrhalis; Naphthyridines; Respiratory Tract Infections; Staphylococcus; Streptococcus pneumoniae	2005
Macrolide-resistance mechanisms in Streptococcus pneumoniae isolates from Belgium. Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases, 2005, Volume: 11, Issue:4 Topics: Anti-Bacterial Agents; Bacterial Proteins; Belgium; Clindamycin; Drug Resistance, Bacterial; Erythromycin; Genes, Bacterial; Humans; Ketolides; Macrolides; Membrane Proteins; Methyltransferases; Microbial Sensitivity Tests; Mutation; RNA, Ribosomal, 23S; Streptococcus pneumoniae	2005
Structures of MLSBK antibiotics bound to mutated large ribosomal subunits provide a structural explanation for resistance. Cell, 2005, Apr-22, Volume: 121, Issue:2 Topics: Anti-Bacterial Agents; Azithromycin; Binding Sites; Clindamycin; Crystallography; Drug Resistance, Bacterial; Erythromycin; Escherichia coli; Haloarcula marismortui; Ketolides; Mutation; Protein Binding; Ribosomes; RNA, Ribosomal, 23S; Virginiamycin	2005
Cellular uptake and efflux of azithromycin, erythromycin, clarithromycin, telithromycin, and cethromycin. Antimicrobial agents and chemotherapy, 2005, Volume: 49, Issue:6 Topics: Animals; Anti-Bacterial Agents; Azithromycin; Cell Line; Clarithromycin; Dogs; Epithelial Cells; Erythromycin; Humans; Ketolides; Macrolides; Mice; Neutrophils; Phagocytes	2005
Multicenter study of the mechanisms of resistance and clonal relationships of Streptococcus agalactiae isolates resistant to macrolides, lincosamides, and ketolides in Spain. Antimicrobial agents and chemotherapy, 2005, Volume: 49, Issue:6 Topics: Anti-Bacterial Agents; Bacterial Proteins; Drug Resistance, Multiple, Bacterial; Erythromycin; Female; Humans; Infant, Newborn; Ketolides; Lincosamides; Macrolides; Microbial Sensitivity Tests; Pregnancy; Pregnancy Complications, Infectious; Spain; Streptococcal Infections; Streptococcus agalactiae	2005
Induction of telithromycin resistance by erythromycin in isolates of macrolide-resistant Staphylococcus spp. Antimicrobial agents and chemotherapy, 2005, Volume: 49, Issue:7 Topics: Anti-Bacterial Agents; Bacterial Proteins; Coagulase; Drug Resistance, Multiple, Bacterial; Erythromycin; Gene Expression Regulation, Bacterial; Humans; Ketolides; Macrolides; Microbial Sensitivity Tests; Staphylococcus; Staphylococcus aureus	2005
Molecular characterization of the first telithromycin-resistant Streptococcus pneumoniae isolate in Germany. Antimicrobial agents and chemotherapy, 2005, Volume: 49, Issue:8 Topics: Aged; Anti-Bacterial Agents; Bacterial Proteins; Drug Resistance, Bacterial; Erythromycin; Germany; Humans; Ketolides; Macrolides; Membrane Proteins; Microbial Sensitivity Tests; Pneumonia, Pneumococcal; Streptococcus pneumoniae	2005
Molecular basis of macrolide resistance in Campylobacter: role of efflux pumps and target mutations. The Journal of antimicrobial chemotherapy, 2005, Volume: 56, Issue:3 Topics: Anti-Bacterial Agents; Campylobacter; Clarithromycin; Dipeptides; DNA, Ribosomal; Drug Resistance, Multiple, Bacterial; Erythromycin; Ketolides; Macrolides; Membrane Transport Proteins; Microbial Sensitivity Tests; Mutation	2005
Characterization of erythromycin-resistant Streptococcus pneumoniae in Korea, and In Vitro activity of telithromycin against erythromycin-resistant Streptococcus pneumoniae. Microbial drug resistance (Larchmont, N.Y.), 2005,Fall, Volume: 11, Issue:3 Topics: Anti-Bacterial Agents; Drug Resistance, Bacterial; Erythromycin; Genotype; Ketolides; Korea; Microbial Sensitivity Tests; Phenotype; Streptococcus pneumoniae	2005
Expression of the mef(E) gene encoding the macrolide efflux pump protein increases in Streptococcus pneumoniae with increasing resistance to macrolides. Antimicrobial agents and chemotherapy, 2005, Volume: 49, Issue:11 Topics: Azithromycin; Bacterial Proteins; Clindamycin; Drug Resistance, Bacterial; Erythromycin; Gene Dosage; Humans; Ketolides; Macrolides; Membrane Proteins; Phenotype; Promoter Regions, Genetic; Streptococcus pneumoniae	2005
Synthesis and antibacterial activity of 3-O-acyl-6-O-carbamoyl erythromycin A derivatives. Bioorganic & medicinal chemistry letters, 2006, Feb-15, Volume: 16, Issue:4 Topics: Anti-Bacterial Agents; Bacteria; Erythromycin; Ketolides; Microbial Sensitivity Tests; Molecular Conformation; Stereoisomerism; Structure-Activity Relationship	2006
Resistance to erythromycin and telithromycin in Streptococcus pyogenes isolates obtained between 1999 and 2002 from Greek children with tonsillopharyngitis: phenotypic and genotypic analysis. Antimicrobial agents and chemotherapy, 2006, Volume: 50, Issue:1 Topics: Acute Disease; Child; Child, Preschool; Drug Resistance, Bacterial; Erythromycin; Genotype; Greece; Humans; Ketolides; Pharyngitis; Phenotype; Streptococcal Infections; Streptococcus pyogenes; Tonsillitis	2006
Sampling the antibiotic resistome. Science (New York, N.Y.), 2006, Jan-20, Volume: 311, Issue:5759 Topics: Amino Acid Substitution; Anti-Bacterial Agents; Ciprofloxacin; Daptomycin; Drug Resistance, Multiple, Bacterial; Erythromycin; Genes, Bacterial; Ketolides; Macrolides; Microbial Sensitivity Tests; Molecular Sequence Data; Mutation; Rifampin; Soil Microbiology; Streptomyces; Trimethoprim Resistance; Vancomycin Resistance; Virginiamycin	2006
Activities of telithromycin, erythromycin, fluoroquinolones, and doxycycline against Campylobacter strains isolated from Finnish subjects. Antimicrobial agents and chemotherapy, 2006, Volume: 50, Issue:3 Topics: Anti-Bacterial Agents; Campylobacter; Doxycycline; Erythromycin; Finland; Fluoroquinolones; Humans; Ketolides; Microbial Sensitivity Tests	2006
Differentiation of arrhythmia risk of the antibacterials moxifloxacin, erythromycin, and telithromycin based on analysis of monophasic action potential duration alternans and cardiac instability. The Journal of pharmacology and experimental therapeutics, 2006, Volume: 318, Issue:1 Topics: Action Potentials; Animals; Arrhythmias, Cardiac; Aza Compounds; Cell Line; Dose-Response Relationship, Drug; Erythromycin; Ether-A-Go-Go Potassium Channels; Fluoroquinolones; Guinea Pigs; Heart Rate; Humans; Ketolides; Moxifloxacin; Quinolines; Risk Factors; Torsades de Pointes	2006
Synthesis and antibacterial activity of novel C12 ethyl ketolides. Bioorganic & medicinal chemistry, 2006, Aug-15, Volume: 14, Issue:16 Topics: Animals; Anti-Bacterial Agents; Erythromycin; Ketolides; Methylation; Mice; Microbial Sensitivity Tests; Respiratory Tract Infections; Ribosomes; Streptococcus pneumoniae; Structure-Activity Relationship	2006
Resistance phenotypes conferred by macrolide phosphotransferases. FEMS microbiology letters, 2007, Volume: 269, Issue:2 Topics: Amino Acid Sequence; Anti-Bacterial Agents; Drug Resistance, Bacterial; Erythromycin; Escherichia coli; Ketolides; Macrolides; Microbial Sensitivity Tests; Molecular Sequence Data; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Plasmids; Recombination, Genetic	2007
Activities of 16-membered ring macrolides and telithromycin against different genotypes of erythromycin-susceptible and erythromycin-resistant Streptococcus pyogenes and Streptococcus pneumoniae. The Journal of antimicrobial chemotherapy, 2007, Volume: 59, Issue:6 Topics: Anti-Bacterial Agents; Drug Resistance, Bacterial; Erythromycin; Genotype; Humans; Italy; Ketolides; Macrolides; Microbial Sensitivity Tests; Pneumococcal Infections; Reverse Transcriptase Polymerase Chain Reaction; Streptococcal Infections; Streptococcus pneumoniae; Streptococcus pyogenes	2007
Activities of clindamycin, synercid, telithromycin, linezolid, and mupirocin against Gram-positive coccal strains resistant to erythromycin in Korea. Archives of pharmacal research, 2007, Volume: 30, Issue:7 Topics: Acetamides; Anti-Bacterial Agents; Clindamycin; Drug Resistance, Bacterial; Erythromycin; Gram-Positive Bacterial Infections; Gram-Positive Cocci; Humans; Ketolides; Korea; Linezolid; Microbial Sensitivity Tests; Mupirocin; Oxazolidinones; Virginiamycin	2007
In vitro activity of telithromycin and quinupristin/dalfopristin against methicillin-resistant coagulase-negative staphylococci with defined resistance genotypes. Folia microbiologica, 2007, Volume: 52, Issue:6 Topics: Anti-Bacterial Agents; Clindamycin; Coagulase; Drug Resistance, Bacterial; Erythromycin; Ketolides; Macrolides; Methicillin Resistance; Microbial Sensitivity Tests; Staphylococcus; Streptogramin A; Streptogramin B; Virginiamycin	2007
The intracellular accumulation of phagocytic and epithelial cells and the inhibitory effect on Chlamydophila (Chlamydia) pneumoniae of telithromycin and comparator antimicrobials. Journal of chemotherapy (Florence, Italy), 2008, Volume: 20, Issue:4 Topics: Anti-Bacterial Agents; Cell Line; Chlamydophila pneumoniae; Ciprofloxacin; Clarithromycin; Dose-Response Relationship, Drug; Epithelial Cells; Erythromycin; Humans; Ketolides; Microbial Sensitivity Tests; Minocycline; Phagocytes	2008
In vitro compared activity of telithromycin and azithromycin against northwest Italian isolates of Streptococcus pyogenes and Streptococcus pneumoniae with different erythromycin susceptibility. Letters in applied microbiology, 2008, Volume: 47, Issue:4 Topics: Adult; Anti-Bacterial Agents; Azithromycin; Child; Drug Resistance, Bacterial; Erythromycin; Humans; Italy; Ketolides; Microbial Sensitivity Tests; Streptococcal Infections; Streptococcus pneumoniae; Streptococcus pyogenes	2008
Synthesis of novel macrolide derivatives with imidazo[4,5-b]pyridinyl sulfur contained alkyl side chains and their antibacterial activity. Bioorganic & medicinal chemistry letters, 2009, Aug-01, Volume: 19, Issue:15 Topics: Anti-Bacterial Agents; Chemistry, Pharmaceutical; Clarithromycin; Drug Design; Drug Resistance, Multiple, Bacterial; Erythromycin; Humans; Imidazoles; Ketolides; Macrolides; Microbial Sensitivity Tests; Models, Chemical; Respiratory Tract Infections; Staphylococcus aureus; Streptococcus pneumoniae; Sulfides; Sulfur	2009
CEM-101 activity against Gram-positive organisms. Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:5 Topics: Anti-Bacterial Agents; Azithromycin; Ceftriaxone; Clarithromycin; Drug Resistance, Bacterial; Drug Synergism; Erythromycin; Gentamicins; Gram-Positive Bacteria; Ketolides; Macrolides; Microbial Sensitivity Tests; Ofloxacin; Staphylococcus aureus; Staphylococcus epidermidis; Streptococcus pneumoniae; Streptococcus pyogenes; Triazoles; Trimethoprim, Sulfamethoxazole Drug Combination; Vancomycin	2010
Detection of a new erm(X)-mediated antibiotic resistance in Egyptian cutaneous propionibacteria. Anaerobe, 2010, Volume: 16, Issue:4 Topics: Acne Vulgaris; Anti-Bacterial Agents; Blotting, Southern; Clindamycin; DNA Transposable Elements; DNA, Bacterial; Drug Resistance, Bacterial; Egypt; Erythromycin; Gene Dosage; Humans; Ketolides; Macrolides; Polymerase Chain Reaction; Propionibacteriaceae; Sequence Analysis, DNA; Sequence Homology, Nucleic Acid; Skin Diseases, Bacterial; Transcriptional Activation	2010
Disposition of oral telithromycin in foals and in vitro activity of the drug against macrolide-susceptible and macrolide-resistant Rhodococcus equi isolates. Journal of veterinary pharmacology and therapeutics, 2010, Volume: 33, Issue:4 Topics: Administration, Oral; Animals; Anti-Bacterial Agents; Azithromycin; Bronchoalveolar Lavage; Bronchoalveolar Lavage Fluid; Clarithromycin; Drug Resistance, Bacterial; Epithelium; Erythromycin; Female; Horses; Ketolides; Linear Models; Lung; Macrolides; Male; Microbial Sensitivity Tests; Rhodococcus equi	2010
Neuropsychological effects of macrolides. Prescrire international, 2010, Volume: 19, Issue:107 Topics: Anti-Bacterial Agents; Erythromycin; Humans; Ketolides; Macrolides; Mental Disorders	2010
Structures of the Escherichia coli ribosome with antibiotics bound near the peptidyl transferase center explain spectra of drug action. Proceedings of the National Academy of Sciences of the United States of America, 2010, Oct-05, Volume: 107, Issue:40 Topics: Anti-Bacterial Agents; Base Sequence; Chloramphenicol; Clindamycin; Deinococcus; Erythromycin; Escherichia coli; Haloarcula marismortui; Ketolides; Molecular Sequence Data; Molecular Structure; Peptidyl Transferases; Ribosomes; RNA, Ribosomal, 23S; X-Ray Diffraction	2010
Revisiting the structures of several antibiotics bound to the bacterial ribosome. Proceedings of the National Academy of Sciences of the United States of America, 2010, Oct-05, Volume: 107, Issue:40 Topics: Anti-Bacterial Agents; Azithromycin; Bacterial Proteins; Binding Sites; Chloramphenicol; Deinococcus; Erythromycin; Haloarcula marismortui; Ketolides; Molecular Structure; Ribosomes; Thermus thermophilus	2010
Phylogenetic sequence variations in bacterial rRNA affect species-specific susceptibility to drugs targeting protein synthesis. Antimicrobial agents and chemotherapy, 2011, Volume: 55, Issue:9 Topics: Aminoglycosides; Binding Sites; Erythromycin; Ketolides; Macrolides; Microbial Sensitivity Tests; Mycobacterium smegmatis; Phylogeny; RNA, Ribosomal; RNA, Ribosomal, 16S; RNA, Ribosomal, 23S	2011
Investigating the barriers to bioavailability of macrolide antibiotics in the rat. European journal of drug metabolism and pharmacokinetics, 2012, Volume: 37, Issue:3 Topics: Animals; Anti-Bacterial Agents; Biological Availability; Clarithromycin; Erythromycin; Hepatocytes; Ketolides; Macrolides; Male; Microsomes, Liver; Rats; Rats, Sprague-Dawley; Roxithromycin	2012
Insights into the mode of action of novel fluoroketolides, potent inhibitors of bacterial protein synthesis. Antimicrobial agents and chemotherapy, 2014, Volume: 58, Issue:1 Topics: Anti-Bacterial Agents; Bacterial Proteins; Erythromycin; Escherichia coli; Ketolides; Microbial Sensitivity Tests; Protein Biosynthesis; Ribosomes; RNA, Ribosomal, 23S	2014
Parametrization of macrolide antibiotics using the force field toolkit. Journal of computational chemistry, 2015, Oct-15, Volume: 36, Issue:27 Topics: Algorithms; Amino Sugars; Anti-Bacterial Agents; Azithromycin; Binding Sites; Erythromycin; Escherichia coli; Hexoses; Ketolides; Macrolides; Molecular Dynamics Simulation; Ribosomes; Static Electricity; Thermodynamics; Thermus thermophilus; Water	2015
Nascent peptide assists the ribosome in recognizing chemically distinct small molecules. Nature chemical biology, 2016, Volume: 12, Issue:3 Topics: Amino Acids; Anti-Bacterial Agents; Erythromycin; Gene Expression Regulation; Hexoses; Ketolides; Methyltransferases; Peptides; Protein Biosynthesis; Ribosomes; Substrate Specificity; Transcriptional Activation	2016
Antimicrobial resistance of Staphylococcus aureus isolated from skin infections and its implications in various clinical conditions in Korea. International journal of dermatology, 2016, Volume: 55, Issue:4 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Child; Child, Preschool; Ciprofloxacin; Clindamycin; Dibekacin; Drug Resistance, Multiple, Bacterial; Erythromycin; Female; Fusidic Acid; Gentamicins; Humans; Infant; Infant, Newborn; Ketolides; Male; Methicillin-Resistant Staphylococcus aureus; Middle Aged; Mupirocin; Oxacillin; Republic of Korea; Retrospective Studies; Rifampin; Staphylococcal Skin Infections; Staphylococcus aureus; Teicoplanin; Tetracycline; Vancomycin; Virginiamycin; Young Adult	2016
Toward the rational design of macrolide antibiotics to combat resistance. Chemical biology & drug design, 2017, Volume: 90, Issue:5 Topics: Anti-Bacterial Agents; Azithromycin; Drug Design; Drug Resistance, Bacterial; Erythromycin; Escherichia coli; Escherichia coli Infections; Humans; Ketolides; Macrolides; Molecular Dynamics Simulation; Point Mutation; Ribosomes	2017
Adhesion and biofilm formation by Staphylococcus aureus clinical isolates under conditions relevant to the host: relationship with macrolide resistance and clonal lineages. Journal of medical microbiology, 2019, Volume: 68, Issue:2 Topics: A549 Cells; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Bacterial Adhesion; Bacterial Proteins; Biofilms; Clindamycin; Drug Resistance, Bacterial; Electrophoresis, Gel, Pulsed-Field; Erythromycin; Female; Genotype; Humans; Ketolides; Macrolides; Male; Methicillin-Resistant Staphylococcus aureus; Middle Aged; Multilocus Sequence Typing; Penicillin-Binding Proteins; Phenotype; Staphylococcal Infections; Staphylococcus aureus; Young Adult	2019
Cytotoxic comparison of macrolide antibiotics and their chlorinated disinfection byproduct mixtures. Ecotoxicology and environmental safety, 2019, Oct-30, Volume: 182 Topics: Anti-Bacterial Agents; Disinfectants; Disinfection; Drinking Water; Erythromycin; Halogenation; Ketolides; Toxicity Tests; Water Pollutants, Chemical; Water Purification	2019
Solithromycin Can Specifically Induce Macrolide-Lincosamide-Streptogramin B Resistance. Microbial drug resistance (Larchmont, N.Y.), 2020, Volume: 26, Issue:9 Topics: Anti-Bacterial Agents; Bacillus subtilis; Bacterial Proteins; Clindamycin; Drug Resistance, Bacterial; Erythromycin; Escherichia coli; Gene Expression Regulation, Bacterial; Genes, Reporter; Genetic Engineering; Ketolides; Lac Operon; Lincosamides; Macrolides; Methyltransferases; Microbial Sensitivity Tests; Miocamycin; Staphylococcus aureus; Streptogramin B; Transformation, Bacterial; Triazoles	2020
Structural and mechanistic basis for translation inhibition by macrolide and ketolide antibiotics. Nature communications, 2021, 07-22, Volume: 12, Issue:1 Topics: Amino Acid Motifs; Amino Acid Sequence; Anti-Bacterial Agents; Bacillus subtilis; Binding Sites; Cryoelectron Microscopy; Drug Resistance, Microbial; Erythromycin; Genes, Bacterial; Ketolides; Macrolides; Methyltransferases; Molecular Dynamics Simulation; Mutagenesis, Insertional; Protein Biosynthesis; Protein Synthesis Inhibitors; Ribosomes	2021
The antimicrobial activity of cethromycin against Staphylococcus aureus and compared with erythromycin and telithromycin. BMC microbiology, 2023, 04-20, Volume: 23, Issue:1 Topics: Anti-Bacterial Agents; Drug Resistance, Multiple, Bacterial; Erythromycin; Humans; Ketolides; Lincosamides; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Multilocus Sequence Typing; Staphylococcal Infections; Staphylococcus aureus; Streptogramin B	2023