Page last updated: 2024-08-21

erythromycin and probenecid

erythromycin has been researched along with probenecid in 39 studies

Research

Studies (39)

TimeframeStudies, this research(%)All Research%
pre-199015 (38.46)18.7374
1990's3 (7.69)18.2507
2000's11 (28.21)29.6817
2010's10 (25.64)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Johans, C; Kinnunen, PK; Söderlund, T; Suomalainen, P1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Lombardo, F; Obach, RS; Waters, NJ1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Fent, K; Popovic, M; Smital, T; Zaja, R1
Bellman, K; Knegtel, RM; Settimo, L1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Spector, R1
Gray, IR1
Johnson, RC; Luger, SW; Massarotti, EM; Messner, RP; Rahn, DW; Steere, AC; Wong, JB1
Willcox, RR1
Hatos, G1
Platts, WM1
Foster, MT1
Hansson, H; Juhlin, I1
Sim, SK1
Chotiwan, P; Desudchit, P; Dhanamun, B; Nunthapisud, P; Rukjutitum, S; Tattakorn, V1
Corbitt, R; Gant, TW; O'Connor, CK; Thorgeirsson, SS; Thorgeirsson, U1
Blackwell, AL; Singh, G; Thomas, PD1
Choi, CH; Kim, HS; Min, YD1
FLIPPIN, HF; FOLTZ, EL1
KOENIG, MG1
Asakura, E; Baba, K; Hasegawa, T; Kitaichi, K; Nadai, M; Sugie, M; Takagi, K; Torita, S; Zhao, YL1
Hu, J; Liu, H; Liu, X; Wang, G; Xie, L1

Reviews

3 review(s) available for erythromycin and probenecid

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
A survey of problems in the antibiotic treatment of gonorrhoea. With special reference to South-East Asia.
    The British journal of venereal diseases, 1970, Volume: 46, Issue:3

    Topics: Anti-Bacterial Agents; Asia, Southeastern; Chloramphenicol; Erythromycin; Female; Gonorrhea; Humans; Injections; Male; Neisseria gonorrhoeae; Penicillin Resistance; Penicillins; Probenecid; Spectinomycin; Sulfathiazoles; Sulfonamides; Tetracycline

1970
THE TREATMENT OF STAPHYLOCOCCAL INFECTIONS.
    The Medical clinics of North America, 1963, Volume: 47

    Topics: Animals; Anti-Bacterial Agents; Antitoxins; Bacitracin; Carrier State; Erythromycin; Furunculosis; Humans; Immune Sera; Immunotherapy, Active; Methicillin; Novobiocin; Osteomyelitis; Penicillins; Probenecid; Staphylococcal Infections; Toxicology; Toxins, Biological; Vancomycin

1963

Trials

3 trial(s) available for erythromycin and probenecid

ArticleYear
Treatment of early Lyme disease.
    The American journal of medicine, 1992, Volume: 92, Issue:4

    Topics: Adult; Amoxicillin; Antibodies, Bacterial; Azithromycin; Borrelia burgdorferi Group; Doxycycline; Erythema Chronicum Migrans; Erythromycin; Female; Follow-Up Studies; Humans; Immunoglobulin G; Immunoglobulin M; Lyme Disease; Male; Middle Aged; Nervous System Diseases; Pilot Projects; Probenecid; Sensation; Treatment Outcome

1992
Venereal disease: diagnosis and treatment.
    Drugs, 1973, Volume: 5, Issue:2

    Topics: Cephalosporins; Clinical Trials as Topic; Drug Combinations; Erythromycin; Female; Gonorrhea; Humans; Male; Penicillin G Procaine; Penicillins; Probenecid; Sexually Transmitted Diseases; Spectinomycin; Syphilis; Syphilis, Congenital; Tetracycline; Time Factors; Urethritis

1973
Rifampicin-erythromycin combination for the treatment of gonococcal urethritis in men.
    The Southeast Asian journal of tropical medicine and public health, 1984, Volume: 15, Issue:3

    Topics: Adolescent; Adult; Aged; Ampicillin; Clinical Trials as Topic; Costs and Cost Analysis; Drug Therapy, Combination; Erythromycin; Gonorrhea; Humans; Male; Middle Aged; Neisseria gonorrhoeae; Penicillin Resistance; Probenecid; Rifampin; Thailand; Urethritis

1984

Other Studies

33 other study(ies) available for erythromycin and probenecid

ArticleYear
Surface activity profiling of drugs applied to the prediction of blood-brain barrier permeability.
    Journal of medicinal chemistry, 2004, Mar-25, Volume: 47, Issue:7

    Topics: Blood-Brain Barrier; Lipid Bilayers; Micelles; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship; Surface Properties

2004
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Molecular characterization of zebrafish Oatp1d1 (Slco1d1), a novel organic anion-transporting polypeptide.
    The Journal of biological chemistry, 2013, Nov-22, Volume: 288, Issue:47

    Topics: Animals; Evolution, Molecular; Glycosylation; Gonadal Steroid Hormones; HEK293 Cells; Humans; Ion Transport; Organic Anion Transporters; Protein Multimerization; Zebrafish; Zebrafish Proteins

2013
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Gonorrhea--recommended treatment schecules, 1974.
    American family physician, 1975, Volume: 11, Issue:2

    Topics: Adolescent; Ampicillin; Cephalosporins; Child; Child, Preschool; Drug Therapy, Combination; Erythromycin; Female; Gonorrhea; Humans; Infant; Infant, Newborn; Infant, Newborn, Diseases; Male; Penicillin G Procaine; Pharyngitis; Pregnancy; Pregnancy Complications, Infectious; Probenecid; Salpingitis; Spectinomycin; Sulfides; Tetracycline; Tetrazoles; Thiadiazoles; Urethritis

1975
Gonorrhea. Recommended treatment schedules--1974.
    The Journal of pediatrics, 1975, Volume: 86, Issue:5

    Topics: Adolescent; Adult; Age Factors; Ampicillin; Anti-Bacterial Agents; Cefazolin; Child; Child, Preschool; Endophthalmitis; Erythromycin; Female; Follow-Up Studies; Gonorrhea; Hospitalization; Humans; Infant; Infant, Newborn; Male; Penicillin G; Penicillin G Procaine; Pharyngeal Diseases; Pregnancy; Pregnancy Complications, Infectious; Probenecid; Salpingitis; Sex Factors; Spectinomycin; Tetracycline

1975
The transport of gentamicin in the choroid plexus and cerebrospinal fluid.
    The Journal of pharmacology and experimental therapeutics, 1975, Volume: 194, Issue:1

    Topics: Ammonium Sulfate; Animals; Biological Transport, Active; Biopharmaceutics; Brain Chemistry; Carbon Radioisotopes; Cerebrospinal Fluid; Choline; Choroid Plexus; Erythromycin; Gentamicins; In Vitro Techniques; Inulin; Kanamycin; Kinetics; Probenecid; Rabbits; Streptomycin; Tritium

1975
Gonorrhea: recommended treatment schedules-1974. Part II: Disseminated gonococcal infection and gonococcal infection in pediatric patients.
    Obstetrics and gynecology, 1975, Volume: 45, Issue:6

    Topics: Ampicillin; Anti-Bacterial Agents; Child; Child Abuse; Erythromycin; Female; Gonorrhea; Hospitalization; Humans; Immobilization; Infant, Newborn; Infant, Newborn, Diseases; Ophthalmia Neonatorum; Penicillin G; Penicillin G Procaine; Pregnancy; Probenecid; Tetracycline

1975
The choice of antibiotic for treating infective endocarditis.
    The Quarterly journal of medicine, 1975, Volume: 44, Issue:175

    Topics: Adolescent; Adult; Aged; Amoxicillin; Amphotericin B; Aneurysm, Infected; Anti-Bacterial Agents; Bacteria; Cardiac Surgical Procedures; Child; Cloxacillin; Endocarditis; Endocarditis, Bacterial; Erythromycin; Fusidic Acid; Gentamicins; Humans; Kanamycin; Middle Aged; Probenecid; Renal Dialysis; Staphylococcal Infections

1975
Treatment of gonorrhoea by penicillin and a renal blocking agent (probenecid).
    The Medical journal of Australia, 1970, May-30, Volume: 1, Issue:22

    Topics: Ampicillin; Australia; Culture Media; Drug Eruptions; Erythromycin; Gonorrhea; Humans; Kanamycin; Kidney; Male; Microbial Sensitivity Tests; Neisseria gonorrhoeae; Oxytetracycline; Penicillin G Benzathine; Penicillin G Procaine; Penicillin Resistance; Probenecid; Streptomycin; Tetracycline; Urethritis

1970
Diagnosis and treatment of venereal disease.
    Postgraduate medicine, 1971, Volume: 50, Issue:1

    Topics: Adolescent; Adult; Ampicillin; Anti-Bacterial Agents; Erythromycin; False Positive Reactions; Female; Fluorescent Antibody Technique; Gonorrhea; Humans; Male; Neurosyphilis; Penicillin G Benzathine; Penicillin G Procaine; Probenecid; Syphilis; Syphilis Serodiagnosis; Syphilis, Cardiovascular; Syphilis, Latent; Tetracycline; United States

1971
[Therapy and therapy-control in uncomplicated gonorrhea].
    Lakartidningen, 1971, Sep-15, Volume: 68, Issue:38

    Topics: Doxycycline; Erythromycin; Female; Gonorrhea; Humans; Leucomycins; Lincomycin; Male; Neisseria gonorrhoeae; Penicillin G; Penicillin Resistance; Penicillins; Probenecid; Rifampin; Tetracycline

1971
Chemotherapy of gonorrhea: a review of current status.
    Canadian Medical Association journal, 1972, Nov-18, Volume: 107, Issue:10

    Topics: Anti-Bacterial Agents; Cephalosporins; Chloramphenicol; Erythromycin; Gonorrhea; Humans; Kanamycin; Penicillins; Probenecid; Rifampin; Sulfonamides; Trimethoprim

1972
Probenecid as an aid to penicillin therapy.
    The Medical letter on drugs and therapeutics, 1966, Feb-11, Volume: 8, Issue:3

    Topics: Aminosalicylic Acids; Cephalothin; Cloxacillin; Erythromycin; Humans; Methicillin; Penicillin G; Penicillin G Benzathine; Probenecid; Sulfonamides

1966
In vivo induction of liver P-glycoprotein expression by xenobiotics in monkeys.
    Toxicology and applied pharmacology, 1995, Volume: 133, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Body Weight; Densitometry; Diethylstilbestrol; Drug Resistance, Multiple; Electrophoresis, Polyacrylamide Gel; Erythromycin; Female; Gene Expression Regulation; Liver; Macaca mulatta; Male; Organ Size; Probenecid; Rifampin; RNA, Messenger; Tamoxifen

1995
An audit of the problems in management of patients with gonorrhoea.
    International journal of STD & AIDS, 1997, Volume: 8, Issue:3

    Topics: Ampicillin; Anti-Bacterial Agents; Anti-Infective Agents; Antitrichomonal Agents; Bacteriological Techniques; Ciprofloxacin; Drug Therapy, Combination; Erythromycin; Female; Gonorrhea; Humans; Male; Metronidazole; Oxytetracycline; Penicillins; Probenecid; Renal Agents; Reproducibility of Results

1997
Double-edged sword of chemosensitizer: increase of multidrug resistance protein (MRP) in leukemic cells by an MRP inhibitor probenecid.
    Biochemical and biophysical research communications, 2001, Apr-27, Volume: 283, Issue:1

    Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Blotting, Western; Cell Division; Cell Survival; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance, Neoplasm; Enzyme Inhibitors; Erythromycin; HL-60 Cells; Humans; Leukemia, Myeloid, Acute; Multidrug Resistance-Associated Proteins; Ofloxacin; Probenecid; Protein Synthesis Inhibitors; Reverse Transcriptase Polymerase Chain Reaction; Rifampin; RNA, Messenger; Tumor Cells, Cultured; Uricosuric Agents; Vincristine

2001
The newer antimicrobial agents.
    American practitioner and digest of treatment, 1953, Volume: 4, Issue:9

    Topics: Anti-Bacterial Agents; Erythromycin; Humans; Niacin; Nicotinic Acids; Penicillins; Probenecid; Sulfonamides

1953
Possible involvement of the drug transporters P glycoprotein and multidrug resistance-associated protein Mrp2 in disposition of azithromycin.
    Antimicrobial agents and chemotherapy, 2004, Volume: 48, Issue:3

    Topics: Animals; Anti-Bacterial Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azithromycin; Bile; Cyclosporine; Erythromycin; Hyperbilirubinemia; Immunosuppressive Agents; Intestinal Mucosa; Kidney; Liver; Male; Mitochondrial Proteins; Probenecid; Rats; Rats, Sprague-Dawley; Rats, Wistar; Renal Agents; Ribosomal Proteins; Saccharomyces cerevisiae Proteins; Tissue Distribution

2004
Possible multiple transporters were involved in hepatobiliary excretion of antofloxacin in rats.
    Xenobiotica; the fate of foreign compounds in biological systems, 2007, Volume: 37, Issue:6

    Topics: Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Bile; Biological Transport; Cimetidine; Cyclosporine; Diclofenac; Enzyme Inhibitors; Erythromycin; Liver; Male; Membrane Transport Proteins; Ofloxacin; Probenecid; Rats; Rats, Sprague-Dawley; Uricosuric Agents

2007