Page last updated: 2024-08-21

erythromycin and motilin

erythromycin has been researched along with motilin in 139 studies

Research

Studies (139)

Timeframe	Studies, this research(%)	All Research%
pre-1990	6 (4.32)	18.7374
1990's	74 (53.24)	18.2507
2000's	43 (30.94)	29.6817
2010's	15 (10.79)	24.3611
2020's	1 (0.72)	2.80

Authors

Authors	Studies
Boivin, M; Poitras, P; Raymond, MC; Riberdy, M; Trudel, L	1
Shi, XZ; Zhang, JJ	1
Bosso, R; Fiorucci, S; Morelli, A	1
Schusdziarra, V	1
Mortazavi, P; Mueller, BA	1
Bosso, R; Bottini, P; Desando, A; Fiorucci, S; Marino, C; Morelli, A; Scionti, L	1
Baker, RA; Harvey, JR; Liu, YF; Saccone, GT; Thune, A; Toouli, J	2
Calis, KA; Yurkowski, PJ	1
Danielian, P	1
Baker, RA; Costi, D; Saccone, GT; Thune, A; Toouli, J	1
Catnach, SM; Fairclough, PD	1
Annese, V; Bouillon, R; Depoortere, I; Janssens, J; Muls, E; Peeters, T; Tack, J; Vantrappen, G	1
Peeters, TL	2
Ito, Z; Kondo, Y; Mizumoto, A; Omura, S; Otawa, M	1
Arndorfer, RC; Cavanaugh, JH; Koch, TR; Lee, MB; Nellans, HN; Ryan, RP; Sarna, SK; Soergel, KH; Stone, JE; Wood, CM	1
Carlson, RG; Courington, KR; Hocking, MP; Sninsky, CA; Vogel, SB	1
Depoortere, I; Peeters, TL; Vantrappen, G	2
Galligan, JJ; Minocha, A	1
Matthijs, G; Peeters, TL; Vantrappen, G	1
Inatomi, N; Itoh, Z; Marui, S; Omura, S; Satoh, H; Satoh, T	1
Hashimoto, N; Inatomi, N; Itoh, Z; Maki, Y; Omura, S; Satoh, H	1
Maskell, JP; Pilot, MA; Qin, XY; Thomson, HH; Zara, GP	1
Itoh, Z; Kondo, Y; Omura, S; Torii, K	1
Arai, H; Itoh, Z; Kuroume, T; Tomomasa, T; Wakabayashi, K	1
Arai, H; Inoue, M; Itoh, Z; Nakaya, M; Suzuki, T; Wakabayashi, K	1
Arai, H; Itoh, Z; Nakaya, M; Suzuki, T; Wakabayashi, K	1
Haga, N; Inatomi, N; Itoh, Z; Mizumoto, A; Shiba, Y; Yamamoto, O	1
Pagano, AP; Parkman, HP; Ryan, JP; Vozzelli, MA	1
Akagawa, KS; Keicho, N; Kudoh, S; Yotsumoto, H	1
Chaussade, S	1
Depoortere, I; Peeters, TL	2
Bruley des Varannes, S; Chayvialle, JA; Galmiche, JP; Parys, V; Ropert, A; Rozé, C	1
Liu, YG; Nie, YQ; Qian, W	1
Fujikura, K; Itoh, Z; Koyama, H; Ohshima, K; Omura, S; Sakai, T; Sano, I; Satoh, M	1
Falcucci, M; Grossi, L; Lapenna, D; Martelli, L; Marzio, L	1
Elezoglou, V; Kounenis, G; Koutsoviti-Papadopoulou, M	1
Distrutti, E; Fiorucci, S; Gerli, R; Morelli, A	1
Inatomi, N; Itoh, Z; Omura, S	1
Fiorucci, S; Morelli, A; Santucci, L	1
Inatomi, N; Itoh, Z; Omura, S; Satoh, H; Satoh, T	1
Depoortere, I; Dharanipragada, R; Florance, JR; Galdes, A; Macielag, MJ; Marvin, MS; Peeters, TL	1
Cioppi, M; Fayad, J; Little, AG; Pennathur, A; Sieren, GL; Tran, A	1
Chaussade, S; Couturier, D; Guerre, J; Michopoulos, S; Sogni, P	1
Bhatia, V; Broor, SL	1
Cioppi, M; Fayad, JB; Little, AG; Pennathur, A	1
Bologna, SD; Hasler, WL; Owyang, C	1
Coremans, G; Janssens, J; Peeters, T; Tack, J; Vantrappen, G; Wilmer, A	1
Bergmann, H; Gaupmann, G; Granser-Vacariu, GV; Kugi, A; Peeters, TL; Schneider, C; Stacher, G; Wiesnagrotzki, S	1
Fiorucci, S; Morelli, A	1
McCallum, RW; Richards, RD; Weber, FH	1
Itoh, Z; Kawamura, O; Kusano, M; Nishioka, T; Sekiguchi, T	1
Hayashi, N; Itoh, Z; Mizumoto, A; Ohtawa, M; Omura, S; Yanagida, K	1
Itoh, Z; Kawamura, O; Omura, S; Sekiguchi, T	1
Inui, A; Itoh, Z; Mizumoto, A; Omura, S; Satoh, M; Shiba, Y	1
Bains, MS; Burt, M; Fortner, JG; Ginsberg, RJ; McCormack, PM; Pommier, R; Scott, A; Turnbull, AD; Williard, WC; Yeh, S	1
Arruebo, MP; Murillo, MD; Plaza, MA	1
Goebell, H; Layer, P; Rosien, U; Sturm, A; von der Ohe, M	1
Pagano, AP; Parkman, HP; Ryan, JP	1
Inatomi, N; Itoh, Z; Marui, S; Omura, S; Sato, F	2
Ito, S; Sakai, T; Sano, I; Sato, M	1
Aoyama, N; Baba, S; Inui, A; Kasuga, M; Miyamoto, M; Morimoto, S; Nakajima, Y; Ohmoto, A; Okano, H; Ueno, N	1
Arruebo, MP; Guerrero-Lindner, E; Murillo, MD; Plaza, MA	1
Abdullah, NA; Chen, S; Inoue, R; Ito, Y; Tanaka, M; Yamada, K	1
Asai, T	1
Itoh, Z	1
Liu, Y; Luo, S; Wang, X	1
Berseth, CL; Jadcherla, SR; Klee, G	1
Cambray, C; Gimeno, C; López, A; Rovira, A	1
Kitazawa, T; Ohga, A; Taneike, T	1
Lu, G; Sarr, MG; Szurszewski, JH	1
Neubrand, M; Sauerbruch, T	1
Geypens, BJ; Ghoos, YF; Maes, B; Samsom, M; Smout, AJ; Verhagen, MA	1
Toyota, K	1
Bertrand, PP; Bornstein, JC; Clark, MJ; Furness, JB; Jenkinson, KM; Verlinden, M; Wright, T	1
Abramovitz, M; Austin, CP; Bakshi, R; Cascieri, MA; Evans, J; Feighner, SD; Figueroa, D; Howard, AD; Hreniuk, DL; Kargman, S; MacNeil, D; McKee, KK; Nargund, R; O'Neill, G; Palyha, OC; Patchett, AA; Pong, SS; Smith, RG; Stocco, R; Tan, CP; Van Der Ploeg, LH	1
Altomare, DF; Chieppa, DM; De Salvia, MA; Mansi, G; Mitolo, CI; Montagnani, M; Nacci, C; Potenza, MA; Rinaldi, M; Rinaldi, R; Serio, M	1
Samsom, M; Smout, AJ; Van Herwaarden, MA; Van Nispen, CH; Verlinden, M	1
Miller, P; Poitras, P; St-Pierre, S; Takanashi, H; Trudel, L	1
Gonzalez, A; Ryan, RP; Sarna, SK	1
Allen, RG; Chiba, T; Kost, LJ; Phillips, SF; Thomforde, GM	1
Gouda, H; Hirono, S; Omura, S; Sunazuka, T	1
Depoortere, I; Geboes, K; Janssens, J; Missiaen, L; Peeters, TL; Penninckx, F; Takanashi, H; Thijs, T; Van Assche, G	1
Geenen, DJ; Hogan, RB; Mack, RJ; McCallum, RW; Riff, D; Talley, NJ; Verlinden, M	1
Boesiger, P; Brasseur, JG; Dent, J; Faas, H; Feinle, C; Fried, M; Hebbard, GS; Indireshkumar, K; Kunz, P; Schwizer, W; Thumshirn, M	1
Berseth, CL; Jadcherla, SR	1
Dong, M; Matsuura, B; Miller, LJ	1
Depoortere, I	1
Dellagrammaticas, HD; Iacovidou, N; Kapetanakis, J; Megaloyanni, E; Papadimitriou, M	1
De Vos, M; Depoortere, I; Lefebvre, R; Peeters, TL; Schoonjans, R; Van Vlem, B; Vanholder, R	1
Depoortere, I; Peeters, TL; Thielemans, L; Vanden Broeck, J	1
Inauen, W; Netzer, P; Schmitt, B	1
Camilleri, M	1
Roberts, JJ; Shapiro, BL; Steinmetz, WE	1
Cote, N; Harris, WH; Kenney, DG; Koenig, JB; LaMarre, J; Monteith, G; Trout, DR	1
Cuiqiong, Y; Jingkun, Z; Yongge, L; Yuqiang, N	1
Giles, N; Horowitz, M; Jones, KL; Krause, G; O'Donovan, DG; Russo, A; Stevens, JE	1
Itoh, H; Katagiri, F; Takeyama, M	1
Depoortere, I; Peeters, TL; Robberecht, P; Vertongen, P; Waelbroeck, M; Xu, L	1
Ji, M; Lin, L; Lin, Z; Zhang, HJ; Zhao, ZQ	1
Dong, L; Yang, X; Yang, XE	1
Bassil, A; Corcoran, S; Jarvie, EM; North Laidler, VJ; Sanger, GJ	1
Itoh, Z; Kamei, K; Koga, H; Muramatsu, H; Omura, S; Ozaki, K; Sudo, H; Takanashi, H; Yogo, K	1
Cynshi, O; Itoh, Z; Kamei, K; Koga, H; Muramatsu, H; Omura, S; Ozaki, K; Sudo, H; Takanashi, H; Yogo, K	1
Akima, M; Itoh, Z; Kamei, K; Koga, H; Omura, S; Onoma, M; Ozaki, K; Sudo, H; Takanashi, H; Yogo, K	1
Itoh, Z; Koto, M; Omura, S; Ozaki, K; Takanashi, H; Yogo, K	1
Andrews, PL; Bompadre, G; Holbrook, JD; Holmgren, S; Hoyle, CH; Jönsson, E; Olsson, C; Sanger, GJ	1
Jia, YD; Jiang, ZY; Liu, CQ; Tang, M	1
Chen, H; Chen, L; Wang, JJ; Wei, HJ; Yung, WH	1
Cynshi, O; McCallum, RW	1
Depoortere, I; Mitselos, A; Peeters, TL; Vanden Berghe, P	1
Yang, Y	1
Center, SA; Erb, HN; Ramstedt, KL; Randolph, JF; Warner, KL; Yeager, AE	1
Barnes, AA; Bolton, VN; Borman, RA; Cellek, S; Hellström, PM; Jarvie, EM; Lee, K; Macpherson, DT; Matthews, KL; Muir, AI; Näslund, E; Sanger, GJ; Unsworth, WP; Westaway, SM	1
Chapman, MJ; Deane, AM; Fraser, RJ	1
Burlingame, MA; Carreras, CW; Chen, Y; Claypool, M; Crumb, W; Fu, H; Hardy, DJ; Li, Y; Liu, Y; Marquez, S; Myles, DC; Shaw, SJ; Zheng, H	1
Borne, M; Brinquin, L; Cirodde, A; De Rudnicki, S; Janvier, F; Leclerc, T; Libert, N	1
Hoshino, S; Koike, K; Oda, S; Sakahara, S; Sakai, T; Sakata, I; Takahashi, T; Xie, Z	1
Carreras, CW; Claypool, M; Li, Y; Liu, Y; Myles, DC; Shaw, SJ	1
Ghazinour, M; Iranpour, R; Mohammadizadeh, M	1
Carreras, CW; Claypool, M; Liu, Y; Myles, DC; Shaw, SJ	1
Ducrotté, P; Gourcerol, G	1
Brown, AJ; Chen, BE; Devlin, MJ; Geliebter, A; Kissileff, HR; Samuels, F; Walsh, BT; Zimmerli, EJ	1
Abe, M; Furukawa, S; Hiasa, Y; Ikeda, Y; Kumagi, T; Matsuura, B; Miyake, T; Nunoi, H; Onji, M; Ueda, T; Utsunomiya, S	1
Broad, J; Hobson, A; Sanger, GJ; Wang, Y	1
Broad, J; Sanger, GJ	1
Aziz, Q; Broad, J; Bulmer, DC; Dukes, GE; Javid, FA; Sanger, GJ	1
Ang, D; Deloose, E; Depoortere, I; Scarpellini, E; Tack, J; Van Oudenhove, L; Vanuytsel, T	1
Deloose, E; Depoortere, I; Janssen, P; Lannoo, M; Tack, J; Van der Schueren, B	1
Deloose, E; Depoortere, I; Janssen, P; Tack, J; Van den Bergh, O; Van Oudenhove, L; Vos, R	1
Deloose, E; Depoortere, I; Iven, J; Meyer-Gerspach, AC; O'daly, O; Tack, J; Van Oudenhove, L; Weltens, N; Zhao, D	1
Kato, S; Kawamura, T; Matsumoto, K; Matsuura, B; Shindo, M; Takahashi, A; Yoshida, A	1
Chen, Z; Huang, S; Jiang, Y; Li, H; Li, J; Li, Z; Xu, HE; Xu, P; Xu, Y; You, C; Zhang, Y	1
Barford, JM; Bolton, VJ; Brown, SL; Cluff, C; Fell, SC; Jarvie, EM; Johnson, CN; Lawless, K; MacPherson, DT; Mahmood, SR; Matthews, KL; McKay, F; Mitchell, DJ; Mohamed, S; Muir, AI; Myatt, JW; Sanger, GJ; Seal, JT; Smith, B; Stanway, SJ; Stemp, G; Stevens, AJ; Thompson, M; Westaway, SM	1

Reviews

16 review(s) available for erythromycin and motilin

Article	Year
[Erythromycin: a motilin receptor agonist]. Sheng li ke xue jin zhan [Progress in physiology], 1992, Volume: 23, Issue:4 Topics: Animals; Duodenum; Erythromycin; Humans; Motilin; Muscle Contraction; Muscle, Smooth; Receptors, Gastrointestinal Hormone; Receptors, Neuropeptide	1992
Erythromycin in gastrointestinal motility disturbances. The Annals of pharmacotherapy, 1992, Volume: 26, Issue:9 Topics: Clinical Trials as Topic; Erythromycin; Gastrointestinal Diseases; Gastrointestinal Motility; Humans; Motilin; Myoelectric Complex, Migrating	1992
Erythromycin, motilin, and gastroparesis. Clinical pharmacy, 1992, Volume: 11, Issue:11 Topics: Diabetic Neuropathies; Erythromycin; Gastrointestinal Diseases; Gastrointestinal Motility; Humans; Motilin	1992
Erythromycin and the gut. Gut, 1992, Volume: 33, Issue:3 Topics: Animals; Digestive System; Dogs; Erythromycin; Gastrointestinal Motility; Guinea Pigs; Humans; Motilin; Rabbits; Rats; Receptors, Gastrointestinal Hormone; Receptors, Neuropeptide	1992
[The potentials of erythromycin derivatives in the treatment of gastrointestinal motility disorders]. Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1991, Volume: 46, Issue:10-11 Topics: Biliary Tract; Colon; Erythromycin; Esophagogastric Junction; Gastric Emptying; Gastrointestinal Diseases; Gastrointestinal Motility; Humans; Intestinal Pseudo-Obstruction; Motilin	1991
[Has erythromycin a therapeutic role in gastroenterology in 1994?]. Gastroenterologie clinique et biologique, 1994, Volume: 18, Issue:11 Topics: Erythromycin; Gastric Emptying; Gastrointestinal Motility; Humans; Motilin; Receptors, Gastrointestinal Hormone	1994
[Motilide, motilin-like macrolides]. Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme, 1993, Volume: 38, Issue:11 Topics: Animals; Anti-Bacterial Agents; Dogs; Erythromycin; Gastrointestinal Motility; Humans; In Vitro Techniques; Molecular Structure; Motilin; Muscle Contraction; Muscle, Smooth; Receptors, Gastrointestinal Hormone; Receptors, Neuropeptide; Structure-Activity Relationship	1993
Erythromycin and other macrolides as prokinetic agents. Gastroenterology, 1993, Volume: 105, Issue:6 Topics: Animals; Anti-Bacterial Agents; Erythromycin; Esophagus; Gastric Emptying; Gastrointestinal Motility; Humans; Motilin; Myoelectric Complex, Migrating	1993
Erythromycin: a motilin agonist and gastrointestinal prokinetic agent. The American journal of gastroenterology, 1993, Volume: 88, Issue:4 Topics: Animals; Erythromycin; Gastric Emptying; Gastrointestinal Motility; Humans; Motilin; Receptors, Gastrointestinal Hormone; Receptors, Neuropeptide	1993
[Treatment of radiotherapy-induced gastroparesis with erythromycin]. Deutsche medizinische Wochenschrift (1946), 1996, Mar-29, Volume: 121, Issue:13 Topics: Aged; Endometrial Neoplasms; Erythromycin; Female; Gastric Emptying; Gastroparesis; Humans; Motilin; Radiotherapy, Adjuvant	1996
Motilin and clinical application. Peptides, 1997, Volume: 18, Issue:4 Topics: Amino Acid Sequence; Animals; Erythromycin; Gastrointestinal Agents; Gastrointestinal Diseases; Humans; Molecular Sequence Data; Motilin; Sequence Homology, Amino Acid; Structure-Activity Relationship	1997
Motilin and motilin receptors: characterization and functional significance. Verhandelingen - Koninklijke Academie voor Geneeskunde van Belgie, 2001, Volume: 63, Issue:6 Topics: Animals; Brain; Digestive System; Disease Susceptibility; Erythromycin; Gastrointestinal Agents; Humans; Motilin; Receptors, Gastrointestinal Hormone; Receptors, Neuropeptide	2001
[Mechanism and clinical application of erythromycin as a gastrointestinal prokinetic agent in children]. Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics, 2008, Volume: 10, Issue:1 Topics: Anti-Bacterial Agents; Child; Dyspepsia; Erythromycin; Gastroesophageal Reflux; Gastrointestinal Motility; Humans; Motilin; Receptors, Gastrointestinal Hormone; Receptors, Neuropeptide	2008
Prokinetic drugs for feed intolerance in critical illness: current and potential therapies. Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine, 2009, Volume: 11, Issue:2 Topics: Antiemetics; Cholecystokinin; Critical Illness; Dopamine Antagonists; Drug Therapy, Combination; Enteral Nutrition; Erythromycin; Gastric Emptying; Gastrointestinal Agents; Ghrelin; Humans; Metoclopramide; Motilin; Receptors, Opioid, mu; Serotonin Receptor Agonists	2009
[Promotility drugs use in critical care: indications and limits?]. Annales francaises d'anesthesie et de reanimation, 2009, Volume: 28, Issue:11 Topics: Critical Care; Dopamine Antagonists; Enteral Nutrition; Erythromycin; Gastrointestinal Motility; Humans; Metoclopramide; Motilin	2009
[Gastroparesis: pathophysiology and management]. Presse medicale (Paris, France : 1983), 2012, Volume: 41, Issue:7-8 Topics: Digestive System Surgical Procedures; Electric Stimulation Therapy; Erythromycin; Gastroparesis; Humans; Motilin; Treatment Failure	2012

Trials

14 trial(s) available for erythromycin and motilin

Article	Year
Erythromycin enhances fasting and postprandial proximal gastric tone in humans. Gastroenterology, 1995, Volume: 109, Issue:1 Topics: Adult; Analysis of Variance; Atropine; Eating; Erythromycin; Fasting; Female; Humans; Infusions, Intravenous; Male; Motilin; Muscle Contraction; Regression Analysis; Stimulation, Chemical; Stomach	1995
Motilin agonist erythromycin increases human lower esophageal sphincter pressure by stimulation of cholinergic nerves. Digestive diseases and sciences, 1994, Volume: 39, Issue:2 Topics: Adult; Cholinergic Fibers; Double-Blind Method; Erythromycin; Esophagogastric Junction; Female; Humans; Male; Manometry; Motilin; Peristalsis; Pressure	1994
Erythromycin effects on gastric emptying, antral motility and plasma motilin and pancreatic polypeptide concentrations in anorexia nervosa. Gut, 1993, Volume: 34, Issue:2 Topics: Adult; Anorexia Nervosa; Double-Blind Method; Erythromycin; Female; Gastric Emptying; Gastrointestinal Motility; Humans; Male; Middle Aged; Motilin; Pancreatic Polypeptide; Pyloric Antrum	1993
Erythromycin stimulates gastric emptying after esophagectomy with gastric replacement: a randomized clinical trial. The Journal of thoracic and cardiovascular surgery, 1996, Volume: 111, Issue:3 Topics: Adult; Aged; Analysis of Variance; Erythromycin; Esophagectomy; Female; Gastrectomy; Gastric Emptying; Humans; Male; Middle Aged; Motilin; Prospective Studies; Stimulation, Chemical; Technetium Tc 99m Sulfur Colloid	1996
Effects of a new motilide, ABT-229, on gastric emptying and postprandial antroduodenal motility in healthy volunteers. Alimentary pharmacology & therapeutics, 1997, Volume: 11, Issue:6 Topics: Administration, Oral; Adult; Cross-Over Studies; Double-Blind Method; Duodenum; Erythromycin; Gastric Emptying; Gastrointestinal Agents; Gastrointestinal Motility; Humans; Male; Manometry; Motilin; Postprandial Period; Reference Values	1997
The effect of motilin agonist ABT-229 on gastro-oesophageal reflux, oesophageal motility and lower oesophageal sphincter characteristics in GERD patients. Alimentary pharmacology & therapeutics, 2000, Volume: 14, Issue:4 Topics: Adult; Cisapride; Cross-Over Studies; Double-Blind Method; Erythromycin; Esophagus; Female; Gastroesophageal Reflux; Gastrointestinal Agents; Humans; Hydrogen-Ion Concentration; Male; Manometry; Middle Aged; Motilin	2000
Effects of a motilin receptor agonist (ABT-229) on upper gastrointestinal symptoms in type 1 diabetes mellitus: a randomised, double blind, placebo controlled trial. Gut, 2001, Volume: 49, Issue:3 Topics: Adolescent; Adult; Aged; Analysis of Variance; Breath Tests; Diabetes Mellitus, Type 1; Dose-Response Relationship, Drug; Double-Blind Method; Dyspepsia; Erythromycin; Female; Gastric Emptying; Gastrointestinal Agents; Gastroparesis; Humans; Male; Middle Aged; Motilin; Regression Analysis; Treatment Outcome	2001
Effects of ABT-229, a motilin agonist, on acid reflux, oesophageal motility and gastric emptying in patients with gastro-oesophageal reflux disease. Alimentary pharmacology & therapeutics, 2002, Volume: 16, Issue:8 Topics: Adult; Aged; Aged, 80 and over; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Erythromycin; Female; Gastric Emptying; Gastroesophageal Reflux; Gastrointestinal Agents; Gastrointestinal Motility; Humans; Hydrogen-Ion Concentration; Male; Manometry; Middle Aged; Motilin	2002
Effect of the motilin agonist KC 11458 on gastric emptying in diabetic gastroparesis. Alimentary pharmacology & therapeutics, 2004, Aug-01, Volume: 20, Issue:3 Topics: Autonomic Nervous System Diseases; Blood Glucose; Diabetes Mellitus; Diabetic Neuropathies; Erythromycin; Female; Gastric Emptying; Gastroparesis; Humans; Male; Middle Aged; Motilin	2004
Clinical trial: effect of mitemcinal (a motilin agonist) on gastric emptying in patients with gastroparesis - a randomized, multicentre, placebo-controlled study. Alimentary pharmacology & therapeutics, 2007, Oct-15, Volume: 26, Issue:8 Topics: Adolescent; Adult; Aged; Blood Glucose; Diabetes Mellitus; Dose-Response Relationship, Drug; Double-Blind Method; Erythromycin; Female; Gastric Emptying; Gastrointestinal Agents; Gastroparesis; Humans; Male; Middle Aged; Motilin; Placebos; Treatment Outcome	2007
Efficacy of prophylactic oral erythromycin to improve enteral feeding tolerance in preterm infants: a randomised controlled study. Singapore medical journal, 2010, Volume: 51, Issue:12 Topics: Enteral Nutrition; Erythromycin; Female; Gestational Age; Humans; Infant, Newborn; Infant, Premature; Male; Motilin; Treatment Outcome	2010
Gastric emptying and symptoms of bulimia nervosa: effect of a prokinetic agent. Physiology & behavior, 2012, May-15, Volume: 106, Issue:2 Topics: Adolescent; Adult; Bulimia Nervosa; Cholecystokinin; Double-Blind Method; Erythromycin; Female; Gastric Emptying; Gastrointestinal Agents; Ghrelin; Humans; Middle Aged; Motilin; Peptide YY	2012
The motilin receptor agonist erythromycin stimulates hunger and food intake through a cholinergic pathway. The American journal of clinical nutrition, 2016, Volume: 103, Issue:3 Topics: Adult; Cholinergic Agents; Eating; Erythromycin; Fasting; Female; Gastrointestinal Agents; Humans; Hunger; Male; Motilin; Muscle Contraction; Myoelectric Complex, Migrating; Receptors, Gastrointestinal Hormone; Receptors, Neuropeptide; Single-Blind Method; Young Adult	2016
The motilin agonist erythromycin increases hunger by modulating homeostatic and hedonic brain circuits in healthy women: a randomized, placebo-controlled study. Scientific reports, 2018, 01-29, Volume: 8, Issue:1 Topics: Adult; Appetite; Brain; Cross-Over Studies; Eating; Erythromycin; Female; Ghrelin; Glucose; Homeostasis; Humans; Hunger; Insulin; Motilin; Women's Health	2018

Other Studies

109 other study(ies) available for erythromycin and motilin

Article	Year
Motilin and the postprandial motility of the antrum. Canadian journal of physiology and pharmacology, 1992, Volume: 70, Issue:11 Topics: Adolescent; Adult; Canada; Eating; Erythromycin; Female; Gastrointestinal Motility; Humans; Male; Motilin; Muscle Contraction; Muscle, Smooth; Pyloric Antrum	1992
Erythromycin stimulates gallbladder emptying and motilin release by atropine-sensitive pathways. Digestive diseases and sciences, 1992, Volume: 37, Issue:11 Topics: Adult; Analysis of Variance; Atropine; Dose-Response Relationship, Drug; Erythromycin; Fasting; Female; Gallbladder; Gallbladder Emptying; Humans; Male; Middle Aged; Motilin; Reference Values; Somatostatin; Time Factors; Ultrasonography	1992
[Motilin and motilides--future perspectives for therapy of gastrointestinal motility disorders]. Zeitschrift fur Gastroenterologie, 1992, Volume: 30, Issue:8 Topics: Autonomic Nervous System Diseases; Diabetes Mellitus, Type 1; Diabetic Neuropathies; Erythromycin; Gastric Emptying; Gastrointestinal Motility; Humans; Motilin; Stomach	1992
Effect of erythromycin on gallbladder emptying in diabetic patients with and without autonomic neuropathy and high levels of motilin. Digestive diseases and sciences, 1992, Volume: 37, Issue:11 Topics: Adult; Analysis of Variance; Atropine; Autonomic Nervous System Diseases; Diabetic Neuropathies; Erythromycin; Female; Gallbladder; Gallbladder Emptying; Heart Diseases; Humans; Male; Motilin; Ultrasonography	1992
Sphincter of Oddi regulates flow by acting as a variable resistor to flow. The American journal of physiology, 1992, Volume: 263, Issue:5 Pt 1 Topics: Animals; Bile; Cisapride; Erythromycin; Female; Male; Motilin; Opossums; Piperidines; Pressure; Sphincter of Oddi	1992
Erythromycin and motilin stimulate sphincter of Oddi motility and inhibit trans-sphincteric flow in the Australian possum. Naunyn-Schmiedeberg's archives of pharmacology, 1992, Volume: 346, Issue:6 Topics: Animals; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Erythromycin; Female; Gastrointestinal Motility; Male; Motilin; Opossums; Sphincter of Oddi; Tetrodotoxin	1992
Erythromycin, motilin, and meconium. American journal of obstetrics and gynecology, 1992, Volume: 166, Issue:2 Topics: Erythromycin; Female; Humans; Infant, Newborn; Meconium; Motilin; Pregnancy; Ureaplasma Infections; Ureaplasma urealyticum	1992
Motilin and erythromycin enhance the in vitro contractile activity of the sphincter of Oddi of the Australian brush-tailed possum. Naunyn-Schmiedeberg's archives of pharmacology, 1992, Volume: 345, Issue:1 Topics: Animals; Atropine; Calcium; Calcium Channel Blockers; Electrophysiology; Erythromycin; Gallbladder; Motilin; Muscle Contraction; Muscle, Smooth; Opossums; Sphincter of Oddi	1992
Effect of erythromycin on gastric motility in controls and in diabetic gastroparesis. Gastroenterology, 1992, Volume: 103, Issue:1 Topics: Adult; Aged; Diabetes Complications; Erythromycin; Female; Gastrointestinal Diseases; Gastrointestinal Motility; Humans; Male; Middle Aged; Motilin; Paralysis; Reference Values	1992
[Effect of motilin agonist, EM-523 on gastrointestinal motility]. Nihon Geka Gakkai zasshi, 1991, Volume: 92, Issue:9 Topics: Animals; Dogs; Erythromycin; Gastrointestinal Motility; Motilin	1991
Gastrointestinal motor effects of erythromycin in humans. Gastroenterology, 1991, Volume: 101, Issue:6 Topics: Abdominal Pain; Adult; Eating; Erythromycin; Fasting; Gastric Emptying; Gastrointestinal Motility; Humans; Intestine, Small; Male; Motilin; Peristalsis; Pyloric Antrum	1991
Hastening gut transit. Lancet (London, England), 1990, Oct-20, Volume: 336, Issue:8721 Topics: Cisapride; Erythromycin; Gastrointestinal Transit; Humans; Motilin; Piperidines; Serotonin Antagonists; Time Factors	1990
Erythromycin enhances delayed gastric emptying in dogs after Roux-Y antrectomy. American journal of surgery, 1991, Volume: 161, Issue:1 Topics: Administration, Oral; Anastomosis, Roux-en-Y; Animals; Dogs; Erythromycin; Gastric Emptying; Infusions, Intravenous; Jejunum; Metoclopramide; Motilin; Pyloric Antrum; Stomach; Vagotomy, Truncal	1991
Effect of erythromycin and of octreotide on motilin receptor density in the rabbit. Regulatory peptides, 1991, Feb-01, Volume: 32, Issue:2 Topics: Animals; Dose-Response Relationship, Drug; Erythromycin; Motilin; Muscle, Smooth; Octreotide; Rabbits; Receptors, Gastrointestinal Hormone; Receptors, Neuropeptide	1991
Erythromycin inhibits contractions of nerve-muscle preparations of the guinea pig small intestine. The Journal of pharmacology and experimental therapeutics, 1991, Volume: 257, Issue:3 Topics: Animals; Erythromycin; Gastrointestinal Motility; Guinea Pigs; In Vitro Techniques; Intestine, Small; Male; Motilin; Muscle Contraction; Muscle, Smooth; Neuromuscular Junction; Parasympathetic Nervous System; Reflex	1991
Ca2+ dependence of motilide-induced contractions in rabbit duodenal muscle strips in vitro. Naunyn-Schmiedeberg's archives of pharmacology, 1991, Volume: 343, Issue:2 Topics: Animals; Calcium; Duodenum; Erythromycin; In Vitro Techniques; Molecular Structure; Motilin; Muscle Contraction; Muscle, Smooth; Rabbits	1991
Development of motilin receptors and of motilin- and erythromycin-induced contractility in rabbits. Gastroenterology, 1990, Volume: 99, Issue:3 Topics: Acetylcholine; Animals; Erythromycin; Gastrointestinal Motility; In Vitro Techniques; Intestine, Small; Motilin; Muscle Contraction; Muscle Development; Muscle, Smooth; Organ Size; Pyloric Antrum; Rabbits; Receptors, Gastrointestinal Hormone; Receptors, Neuropeptide; Regression Analysis	1990
EM-523, an erythromycin derivative, and motilin show similar contractile activity in isolated rabbit intestine. The Journal of pharmacology and experimental therapeutics, 1990, Volume: 254, Issue:3 Topics: Acetylcholine; Animals; Atropine; Dinoprost; Drug Interactions; Erythromycin; Female; Guinea Pigs; Intestine, Small; Male; Motilin; Muscle Contraction; Muscle, Smooth; Rabbits; Rats; Rats, Inbred Strains; Species Specificity; Tetrodotoxin	1990
An erythromycin derivative, EM-523, induces motilin-like gastrointestinal motility in dogs. The Journal of pharmacology and experimental therapeutics, 1989, Volume: 251, Issue:2 Topics: Animals; Atropine; Dogs; Erythromycin; Fasting; Gastrointestinal Motility; Male; Motilin; Receptors, Gastrointestinal Hormone; Receptors, Neuropeptide; Vomiting	1989
Erythromycin and gastrointestinal motility. Lancet (London, England), 1987, Oct-31, Volume: 2, Issue:8566 Topics: Animals; Dogs; Erythromycin; Gastrointestinal Motility; Humans; Motilin; Vomiting	1987
Erythromycin and its derivatives with motilin-like biological activities inhibit the specific binding of 125I-motilin to duodenal muscle. Biochemical and biophysical research communications, 1988, Jan-29, Volume: 150, Issue:2 Topics: Animals; Duodenum; Erythromycin; In Vitro Techniques; Kinetics; Motilin; Muscle, Smooth; Rabbits; Receptors, Gastrointestinal Hormone; Receptors, Neuropeptide; Structure-Activity Relationship	1988
Erythromycin induces migrating motor complex in human gastrointestinal tract. Digestive diseases and sciences, 1986, Volume: 31, Issue:2 Topics: Adult; Erythromycin; Gastrointestinal Motility; Humans; Infusions, Parenteral; Motilin; Muscle Contraction; Sodium Chloride; Stimulation, Chemical	1986
Structure-activity relation among macrolide antibiotics in initiation of interdigestive migrating contractions in the canine gastrointestinal tract. The American journal of physiology, 1985, Volume: 248, Issue:3 Pt 1 Topics: Animals; Anti-Bacterial Agents; Dogs; Erythromycin; Female; Gastrointestinal Motility; Leucomycins; Male; Motilin; Oleandomycin; Spiramycin; Stimulation, Chemical; Structure-Activity Relationship; Tylosin	1985
Erythromycin mimics exogenous motilin in gastrointestinal contractile activity in the dog. The American journal of physiology, 1984, Volume: 247, Issue:6 Pt 1 Topics: Animals; Dogs; Eating; Erythromycin; Female; Gastrointestinal Hormones; Gastrointestinal Motility; Infusions, Parenteral; Male; Motilin; Pentagastrin; Radioimmunoassay; Secretin	1984
Stimulatory mechanism of EM523-induced contractions in postprandial stomach of conscious dogs. Gastroenterology, 1995, Volume: 109, Issue:5 Topics: Animals; Anti-Bacterial Agents; Atropine; Dipeptides; Dogs; Dopamine; Eating; Erythromycin; Hexamethonium; Indoles; Motilin; Muscle Contraction; Naloxone; Ondansetron; Serotonin Antagonists; Stomach; Substance P	1995
Gastrokinetic effects of erythromycin: myogenic and neurogenic mechanisms of action in rabbit stomach. The American journal of physiology, 1995, Volume: 269, Issue:3 Pt 1 Topics: Adrenergic Antagonists; Animals; Bethanechol; Cholinergic Antagonists; Dose-Response Relationship, Drug; Erythromycin; Gastric Fundus; Gastrointestinal Motility; Motilin; Muscle, Smooth; Nervous System Physiological Phenomena; Pyloric Antrum; Rabbits; Stomach; Substance P	1995
Antilymphocytic activity of erythromycin distinct from that of FK506 or cyclosporin A. The Journal of antibiotics, 1993, Volume: 46, Issue:9 Topics: Antigens; Cell Line; Concanavalin A; Cyclosporine; Drug Synergism; Erythromycin; Humans; Immunosuppressive Agents; Interleukin-2; Lymphocyte Activation; Lymphocytes; Motilin; Receptors, Interleukin-2; Tacrolimus; Tumor Cells, Cultured	1993
Transduction mechanism of motilin and motilides in rabbit duodenal smooth muscle. Regulatory peptides, 1995, Feb-14, Volume: 55, Issue:3 Topics: Adenylyl Cyclases; Animals; Carbachol; Duodenum; Erythromycin; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Inositol; Inositol Phosphates; Motilin; Muscle, Smooth; Rabbits; Receptors, Gastrointestinal Hormone; Receptors, Neuropeptide; Signal Transduction; Tritium	1995
[Clinical study of erythromycin action on gallbladder motility in patients with non-ulcer dyspepsia]. Zhonghua nei ke za zhi, 1994, Volume: 33, Issue:6 Topics: Adult; Dyspepsia; Erythromycin; Female; Gallbladder Emptying; Humans; Male; Motilin	1994
EM574, an erythromycin derivative, is a potent motilin receptor agonist in human gastric antrum. The Journal of pharmacology and experimental therapeutics, 1994, Volume: 271, Issue:1 Topics: Autoradiography; Binding Sites; Erythromycin; Humans; In Vitro Techniques; Motilin; Muscle Contraction; Pyloric Antrum; Radioligand Assay; Receptors, Gastrointestinal Hormone; Receptors, Neuropeptide	1994
Migrating motor complex recorded spontaneously and induced by motilin and erythromycin in an ex vivo rabbit intestinal preparation. Peptides, 1994, Volume: 15, Issue:6 Topics: Animals; Atropine; Digestive System; Erythromycin; Esophagus; Female; Gastrointestinal Motility; In Vitro Techniques; Intestine, Small; Male; Motilin; Neostigmine; Rabbits; Stomach	1994
Motilin receptor: a model for development of prokinetics. Digestive diseases and sciences, 1994, Volume: 39, Issue:12 Suppl Topics: Animals; Anti-Bacterial Agents; Dogs; Erythromycin; Gastrointestinal Motility; Humans; Motilin; Myoelectric Complex, Migrating; Rabbits; Receptors, Gastrointestinal Hormone; Receptors, Neuropeptide	1994
Effect of erythromycin on different parts of the rabbit intestine: comparison with motilin. General pharmacology, 1994, Volume: 25, Issue:1 Topics: Animals; Colon; Duodenum; Erythromycin; Female; Ileum; In Vitro Techniques; Intestines; Jejunum; Male; Motilin; Muscle Contraction; Muscle, Smooth; Rabbits	1994
Effect of erythromycin on gastric and gallbladder emptying and gastrointestinal symptoms in scleroderma patients is maintained medium term. The American journal of gastroenterology, 1994, Volume: 89, Issue:4 Topics: Drug Administration Schedule; Erythromycin; Female; Gallbladder Emptying; Gastric Emptying; Gastrointestinal Diseases; Gastrointestinal Motility; Humans; Male; Middle Aged; Motilin; Scleroderma, Systemic; Stimulation, Chemical; Time Factors	1994
5-hydroxytryptamine 3-receptor antagonist modulates gallbladder emptying and motilin release induced by erythromycin. Digestive diseases and sciences, 1993, Volume: 38, Issue:12 Topics: Adult; Erythromycin; Female; Food; Gallbladder Emptying; Humans; Male; Motilin; Ondansetron; Serotonin Antagonists	1993
Comparison of the motor-stimulating action of EM523, an erythromycin derivative, and prostaglandin F2 alpha in conscious dogs. Japanese journal of pharmacology, 1993, Volume: 63, Issue:2 Topics: Animals; Atropine; Dinoprost; Dogs; Dopamine; Erythromycin; Fasting; Gastrointestinal Motility; Male; Motilin	1993
The motilin antagonist ANQ-11125 blocks motilide-induced contractions in vitro in the rabbit. Biochemical and biophysical research communications, 1994, Jan-28, Volume: 198, Issue:2 Topics: Animals; Binding, Competitive; Digestive System; Duodenum; Erythromycin; Motilin; Muscle Contraction; Muscle, Smooth; Pyloric Antrum; Rabbits	1994
Erythromycin strengthens the defective lower esophageal sphincter in patients with gastroesophageal reflux disease. American journal of surgery, 1994, Volume: 167, Issue:1 Topics: Erythromycin; Esophagogastric Junction; Female; Gastroesophageal Reflux; Humans; Male; Manometry; Middle Aged; Motilin; Myoelectric Complex, Migrating; Peristalsis; Pressure; Stimulation, Chemical; Time Factors	1994
Erythromycin and the gallbladder. Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology, 1993, Volume: 12, Issue:2 Topics: Cholelithiasis; Erythromycin; Gallbladder; Gallbladder Emptying; Humans; Motilin	1993
Erythromycin, motilin, and the esophagus. Surgery, 1993, Volume: 114, Issue:2 Topics: Adult; Erythromycin; Esophagus; Female; Humans; Male; Middle Aged; Motilin; Muscle Contraction; Myoelectric Complex, Migrating; Pressure	1993
Down-regulation of motilin receptors on rabbit colon myocytes by chronic oral erythromycin. The Journal of pharmacology and experimental therapeutics, 1993, Volume: 266, Issue:2 Topics: Administration, Oral; Animals; Colon; Down-Regulation; Erythromycin; In Vitro Techniques; Male; Motilin; Muscle Contraction; Rabbits; Receptors, Gastrointestinal Hormone; Receptors, Neuropeptide	1993
5-hydroxytryptamine-3 receptors are involved in the initiation of gastric phase-3 motor activity in humans. Gastroenterology, 1993, Volume: 105, Issue:3 Topics: Adult; Digestive System; Digestive System Physiological Phenomena; Duodenum; Erythromycin; Female; Humans; Jejunum; Male; Motilin; Motor Activity; Motor Neurons; Ondansetron; Pyloric Antrum; Receptors, Serotonin; Stomach	1993
Motilin and erythromycin stimulate pepsinogen secretion by chief cells isolated from guinea pig stomach. Gastroenterology, 1993, Volume: 104, Issue:4 Topics: Animals; Atropine; Calcium; Carbachol; Cholecystokinin; Dinoprostone; Erythromycin; Gastric Mucosa; Guinea Pigs; In Vitro Techniques; Kinetics; Male; Motilin; Pepsinogens; Secretin; Vasoactive Intestinal Peptide	1993
Effect of erythromycin on interdigestive gastrointestinal contractile activity and plasma motilin concentration in humans. Digestive diseases and sciences, 1993, Volume: 38, Issue:5 Topics: Adolescent; Adult; Erythromycin; Female; Humans; Male; Motilin; Muscle Contraction; Peristalsis	1993
Mechanism of gastroprokinetic effect of EM523, an erythromycin derivative, in dogs. Gastroenterology, 1993, Volume: 104, Issue:5 Topics: Animals; Atropine; Dogs; Dose-Response Relationship, Drug; Erythromycin; Female; Gastrointestinal Motility; Immune Sera; Male; Motilin	1993
Effect of erythromycin derivative EM523L on human interdigestive gastrointestinal tract. Digestive diseases and sciences, 1993, Volume: 38, Issue:6 Topics: Adult; Digestion; Digestive System; Digestive System Physiological Phenomena; Dose-Response Relationship, Drug; Erythromycin; Gastrointestinal Motility; Humans; Male; Motilin; Reference Values; Time Factors	1993
Effect of nonpeptide motilin agonist EM523 on release of gut and pancreatic hormones in conscious dogs. Gastroenterology, 1996, Volume: 110, Issue:1 Topics: Animals; Atropine; Dogs; Erythromycin; Gastrointestinal Hormones; Motilin; Ondansetron; Pancreatic Hormones; Serotonin Antagonists; Vagotomy	1996
Effect of motilin, somatostatin and bombesin on gastroduodenal myoelectric activity in sheep. Life sciences, 1996, Volume: 58, Issue:17 Topics: Animals; Atropine; Bombesin; Duodenum; Electroencephalography; Erythromycin; Female; Gastrointestinal Motility; Hexamethonium; Motilin; Sheep; Somatostatin; Stomach	1996
Erythromycin inhibits rabbit pyloric smooth muscle through neuronal motilin receptors. Gastroenterology, 1996, Volume: 111, Issue:3 Topics: Animals; Erythromycin; In Vitro Techniques; Motilin; Muscle Contraction; Muscle, Smooth; Neurons; Pylorus; Rabbits; Receptors, Gastrointestinal Hormone; Receptors, Neuropeptide; Tachyphylaxis; Tetrodotoxin	1996
Vagus-dependent and vagus-independent mechanisms of action of the erythromycin derivative EM574 and motilin in dogs. Japanese journal of pharmacology, 1996, Volume: 71, Issue:1 Topics: Animals; Cisapride; Dogs; Erythromycin; Gastrointestinal Agents; Gastrointestinal Motility; Intestine, Small; Male; Motilin; Piperidines; Serotonin Receptor Agonists; Stomach; Vagus Nerve	1996
[Erythromycin derivative EM574 with motilin agonistic effect on human gastric antrum]. Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi, 1995, Volume: 31, Issue:6 Topics: Binding Sites; Dose-Response Relationship, Drug; Erythromycin; Gastrointestinal Agents; Humans; Motilin; Muscle Contraction; Muscle, Smooth; Pyloric Antrum	1995
EM523L, a nonpeptide motilin agonist, stimulates gastric emptying and pancreatic polypeptide secretion. Peptides, 1996, Volume: 17, Issue:6 Topics: Adult; Aged; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Erythromycin; Evaluation Studies as Topic; Female; Gastric Emptying; Gastrointestinal Agents; Humans; Male; Middle Aged; Motilin; Pancreatic Polypeptide	1996
Effect of motilin on gastrointestinal myoelectric activity in conscious rabbits. Peptides, 1996, Volume: 17, Issue:6 Topics: Animals; Atropine; Consciousness; Drug Interactions; Erythromycin; Gastrointestinal Agents; Hexamethonium; Motilin; Myoelectric Complex, Migrating; Ondansetron; Rabbits	1996
Electrophysiological characterization of a motilin agonist, GM611, on rabbit duodenal smooth muscle. The American journal of physiology, 1996, Volume: 271, Issue:6 Pt 1 Topics: Animals; Duodenum; Erythromycin; Gastrointestinal Agents; Male; Motilin; Muscle Contraction; Muscle, Smooth; Patch-Clamp Techniques; Rabbits	1996
Erythromycin and motilin as gastrointestinal prokinetic agents. European journal of anaesthesiology, 1997, Volume: 14, Issue:1 Topics: Animals; Erythromycin; Gastric Emptying; Gastrointestinal Agents; Gastrointestinal Motility; Humans; Motilin	1997
[Effects of changes of plasma motilin level on the motility of gallbladder in patients with chronic renal failure]. Zhonghua nei ke za zhi, 1996, Volume: 35, Issue:2 Topics: Adult; Aged; Erythromycin; Female; Gallbladder Emptying; Humans; Kidney Failure, Chronic; Male; Middle Aged; Motilin	1996
Regulation of migrating motor complexes by motilin and pancreatic polypeptide in human infants. Pediatric research, 1997, Volume: 42, Issue:3 Topics: Anti-Bacterial Agents; Erythromycin; Gestational Age; Hormones; Humans; Infant, Newborn; Infant, Premature; Motilin; Myoelectric Complex, Migrating; Pancreatic Polypeptide; Receptors, Gastrointestinal Hormone; Time Factors	1997
Acute colonic pseudo-obstruction (Ogilvie's syndrome) treated with erythromycin. Intensive care medicine, 1997, Volume: 23, Issue:7 Topics: Aged; Aged, 80 and over; Colonic Pseudo-Obstruction; Diagnosis, Differential; Erythromycin; Fatal Outcome; Humans; Male; Motilin; Radiography	1997
Functional characterization of neural and smooth muscle motilin receptors in the chicken proventriculus and ileum. Regulatory peptides, 1997, Aug-15, Volume: 71, Issue:2 Topics: Animals; Chickens; Dogs; Erythromycin; Gastrointestinal Agents; Hormones; Ileum; Motilin; Muscle Contraction; Muscle, Smooth; Proventriculus; Rabbits; Receptors, Gastrointestinal Hormone; Receptors, Neuropeptide; Swine	1997
Effect of motilin and erythromycin on calcium-activated potassium channels in rabbit colonic myocytes. Gastroenterology, 1998, Volume: 114, Issue:4 Topics: Animals; Calcium; Colon; Erythromycin; Female; Gastrointestinal Agents; Male; Motilin; Potassium Channels; Rabbits	1998
Erythromycin, a motilin agonist, increases postprandial gallbladder emptying during therapy with ursodeoxycholic acid. Zeitschrift fur Gastroenterologie, 1998, Volume: 36, Issue:4 Topics: Administration, Oral; Adult; Cholagogues and Choleretics; Cholelithiasis; Combined Modality Therapy; Drug Synergism; Erythromycin; Gallbladder Emptying; Humans; Lithotripsy; Male; Motilin; Postprandial Period; Reference Values; Ursodeoxycholic Acid	1998
Pyloric opening and closure evaluated by means of strain gauge force transducers. Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi, 1998, Volume: 34, Issue:1 Topics: Animals; Cisapride; Dogs; Duodenum; Erythromycin; Female; Gastrointestinal Agents; Gastrointestinal Motility; Male; Motilin; Muscle Contraction; Pyloric Antrum; Pylorus; Transducers	1998
Erythromycin derivatives ABT 229 and GM 611 act on motilin receptors in the rabbit duodenum. Clinical and experimental pharmacology & physiology, 1999, Volume: 26, Issue:3 Topics: Animals; Anti-Bacterial Agents; Carbachol; Dose-Response Relationship, Drug; Duodenum; Erythromycin; Female; Gastrointestinal Agents; Male; Motilin; Muscle Contraction; Rabbits; Receptors, Gastrointestinal Hormone; Receptors, Neuropeptide	1999
Receptor for motilin identified in the human gastrointestinal system. Science (New York, N.Y.), 1999, Jun-25, Volume: 284, Issue:5423 Topics: Alternative Splicing; Amino Acid Sequence; Base Sequence; Binding Sites; Calcium; Cell Line; Chromosome Mapping; Chromosomes, Human, Pair 13; Cloning, Molecular; Colon; Erythromycin; Gastric Mucosa; GTP-Binding Proteins; Humans; In Situ Hybridization; Intestine, Small; Ligands; Molecular Sequence Data; Motilin; Receptors, Gastrointestinal Hormone; Receptors, Neuropeptide; Thyroid Gland; Transfection	1999
Effects of erythromycin on human colonic circular muscle in idiopathic chronic constipation. European journal of clinical investigation, 2000, Volume: 30, Issue:1 Topics: Adult; Aged; Anti-Bacterial Agents; Chronic Disease; Colon; Constipation; Erythromycin; Humans; In Vitro Techniques; Middle Aged; Motilin; Muscle Contraction; Muscle, Smooth	2000
Neural and muscular receptors for motilin in the rabbit colon. Peptides, 2000, Volume: 21, Issue:2 Topics: Animals; Binding, Competitive; Colon; Duodenum; Erythromycin; Female; Gastrointestinal Motility; Hormone Antagonists; Iodine Radioisotopes; Motilin; Muscle, Smooth; Peptides, Cyclic; Rabbits; Receptors, Gastrointestinal Hormone; Receptors, Neuropeptide; Synaptosomes	2000
EM574, an erythromycin derivative, improves delayed gastric emptying of semi-solid meals in conscious dogs. European journal of pharmacology, 2000, Apr-28, Volume: 395, Issue:2 Topics: Animals; Atropine; Cisapride; Dogs; Erythromycin; Gastric Emptying; Gastrointestinal Agents; Gastroparesis; Male; Motilin; Muscarinic Antagonists; Receptors, Serotonin; Receptors, Serotonin, 5-HT4; Serotonin Receptor Agonists	2000
Enteric locus of action of prokinetics: ABT-229, motilin, and erythromycin. American journal of physiology. Gastrointestinal and liver physiology, 2000, Volume: 278, Issue:5 Topics: Animals; Atropine; Cell Size; Cells, Cultured; Dogs; Duodenum; Electric Stimulation; Erythromycin; Female; Gastrointestinal Agents; Gastrointestinal Motility; Hexamethonium; In Vitro Techniques; Infusions, Intra-Arterial; Intestinal Mucosa; Jejunum; Male; Methacholine Chloride; Motilin; Muscle Contraction; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Rabbits; Stomach; Tetrodotoxin	2000
Motilides accelerate regional gastrointestinal transit in the dog. Alimentary pharmacology & therapeutics, 2000, Volume: 14, Issue:7 Topics: Animals; Dogs; Dose-Response Relationship, Drug; Erythromycin; Female; Gastrointestinal Agents; Gastrointestinal Transit; Motilin; Radionuclide Imaging	2000
Three-dimensional structure-activity relationship analysis between motilin and motilide using conformational analysis and a novel molecular superposing method. Chemical & pharmaceutical bulletin, 2000, Volume: 48, Issue:11 Topics: Erythromycin; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Conformation; Motilin; Structure-Activity Relationship	2000
Contractile effects and intracellular Ca2+ signalling induced by motilin and erythromycin in the circular smooth muscle of human colon. Neurogastroenterology and motility, 2001, Volume: 13, Issue:1 Topics: Acetylcholine; Aged; Anti-Bacterial Agents; Calcium Channel Agonists; Calcium Signaling; Cells, Cultured; Colon; Erythromycin; Ethidium; Fluorescent Dyes; Humans; In Vitro Techniques; Motilin; Muscle Contraction; Muscle, Smooth	2001
Pressure-geometry relationship in the antroduodenal region in humans. American journal of physiology. Gastrointestinal and liver physiology, 2001, Volume: 281, Issue:5 Topics: Duodenum; Erythromycin; Fat Emulsions, Intravenous; Female; Gastric Emptying; Gastrointestinal Agents; Gastrointestinal Motility; Humans; Infusions, Parenteral; Injections, Intravenous; Magnetic Resonance Imaging; Male; Manometry; Motilin; Parenteral Nutrition; Pressure; Pyloric Antrum; Sodium Chloride	2001
Effect of erythromycin on gastroduodenal contractile activity in developing neonates. Journal of pediatric gastroenterology and nutrition, 2002, Volume: 34, Issue:1 Topics: Aging; Digestive System; Digestive System Physiological Phenomena; Dose-Response Relationship, Drug; Erythromycin; Female; Gastrointestinal Agents; Gastrointestinal Motility; Gestational Age; Humans; Infant, Newborn; Infant, Premature; Male; Manometry; Motilin; Myoelectric Complex, Migrating; Perfusion; Receptors, Gastrointestinal Hormone; Receptors, Neuropeptide	2002
Differential determinants for peptide and non-peptidyl ligand binding to the motilin receptor. Critical role of second extracellular loop for peptide binding and action. The Journal of biological chemistry, 2002, Mar-22, Volume: 277, Issue:12 Topics: Amino Acid Sequence; Amino Acids; Animals; Arginine; Calcium; Cell Membrane; COS Cells; Cysteine; Disulfides; Dose-Response Relationship, Drug; Erythromycin; Gene Deletion; Humans; Leucine; Ligands; Molecular Sequence Data; Motilin; Mutagenesis, Site-Directed; Oxygen; Protein Binding; Protein Structure, Tertiary; Protein Synthesis Inhibitors; Receptors, Gastrointestinal Hormone; Receptors, Neuropeptide; Sequence Homology, Amino Acid; Valine	2002
Effect of low-dose oral erythromycin on gastric aspirates in ventilated neonates less than 32 weeks of gestation. Preliminary results. Biology of the neonate, 2002, Volume: 81, Issue:3 Topics: Administration, Oral; Dose-Response Relationship, Drug; Enteral Nutrition; Erythromycin; Gastrointestinal Agents; Gestational Age; Humans; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Motilin; Prospective Studies; Respiration, Artificial; Respiratory Distress Syndrome, Newborn; Stomach; Suction	2002
In vitro evaluation of motilin agonism by macrolide immunosuppressive drugs. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2002, Volume: 17, Issue:6 Topics: Animals; Carbachol; Cyclosporine; Duodenum; Electric Stimulation; Erythromycin; Immunosuppressive Agents; In Vitro Techniques; Kinetics; Male; Motilin; Muscle Contraction; Muscle, Smooth; Rabbits; Sirolimus; Tacrolimus	2002
The motilin pharmacophore in CHO cells expressing the human motilin receptor. Biochemical and biophysical research communications, 2002, May-17, Volume: 293, Issue:4 Topics: Aequorin; Alanine; Animals; Calcium; CHO Cells; Cricetinae; Digestive System; Duodenum; Erythromycin; Gastrointestinal Agents; Humans; Motilin; Protein Binding; Protein Structure, Tertiary; Rabbits; Receptors, Gastrointestinal Hormone; Receptors, Neuropeptide; Structure-Activity Relationship; Swine; Thyroid Gland	2002
Motilin agonists and dyspepsia: throwing out the baby with the bath water. Gut, 2002, Volume: 51, Issue:4 Topics: Dyspepsia; Erythromycin; Gastric Emptying; Humans; Motilin	2002
The structure of erythromycin enol ether as a model for its activity as a motilide. Journal of medicinal chemistry, 2002, Oct-24, Volume: 45, Issue:22 Topics: Erythromycin; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Mimicry; Motilin; Protein Structure, Secondary	2002
Binding of radiolabeled porcine motilin and erythromycin lactobionate to smooth muscle membranes in various segments of the equine gastrointestinal tract. American journal of veterinary research, 2002, Volume: 63, Issue:11 Topics: Animals; Binding, Competitive; Digestive System; Erythromycin; Gastrointestinal Agents; Horses; In Vitro Techniques; Motilin; Muscle, Smooth; Receptors, Gastrointestinal Hormone; Receptors, Neuropeptide	2002
Relationship between plasma motilin and effect of oral erythromycin on gallbladder contraction in patients of functional dyspepsia. Chinese medical sciences journal = Chung-kuo i hsueh k'o hsueh tsa chih, 2000, Volume: 15, Issue:2 Topics: Administration, Oral; Adult; Dyspepsia; Erythromycin; Female; Gallbladder Emptying; Gastrointestinal Agents; Humans; Male; Motilin	2000
Effects of erythromycin on plasma gastrin, somatostatin, and motilin levels in healthy volunteers and postoperative cancer patients. Biological & pharmaceutical bulletin, 2005, Volume: 28, Issue:7 Topics: Adult; Aged; Anti-Bacterial Agents; Case-Control Studies; Erythromycin; Gastric Emptying; Gastrins; Humans; Immunoenzyme Techniques; Male; Middle Aged; Motilin; Neoplasms; Postoperative Period; Somatostatin	2005
Motilin and erythromycin-A share a common binding site in the third transmembrane segment of the motilin receptor. Biochemical pharmacology, 2005, Sep-15, Volume: 70, Issue:6 Topics: Amino Acid Sequence; Animals; Binding Sites; Blotting, Western; CHO Cells; Cricetinae; Erythromycin; Immunohistochemistry; Molecular Sequence Data; Motilin; Receptors, Gastrointestinal Hormone; Receptors, Neuropeptide; Swine	2005
Effect of erythromycin on gastric dysmotility and neuroendocrine peptides in rats with diabetes mellitus. Chinese medical sciences journal = Chung-kuo i hsueh k'o hsueh tsa chih, 2005, Volume: 20, Issue:3 Topics: Animals; Diabetes Mellitus, Experimental; Erythromycin; Gastrointestinal Agents; Gastrointestinal Motility; Male; Motilin; Muscle Contraction; Muscle, Smooth; Pyloric Antrum; Rats; Rats, Sprague-Dawley; Somatostatin; Substance P; Vasoactive Intestinal Peptide	2005
[Effects of motilin agonists on intracellular calcium mobilization in cultured rat myenteric neurons]. Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2006, Volume: 26, Issue:6 Topics: Animals; Animals, Newborn; Calcium; Calcium Signaling; Cells, Cultured; Dose-Response Relationship, Drug; Erythromycin; Microscopy, Confocal; Motilin; Myenteric Plexus; Neurons; Rats; Rats, Sprague-Dawley; Receptors, Gastrointestinal Hormone; Receptors, Neuropeptide	2006
Differences between the abilities of tegaserod and motilin receptor agonists to stimulate gastric motility in vitro. British journal of pharmacology, 2007, Volume: 150, Issue:4 Topics: Animals; Carbachol; Dose-Response Relationship, Drug; Electric Stimulation; Erythromycin; Gastrointestinal Agents; Gastrointestinal Motility; Half-Life; In Vitro Techniques; Indoles; Ligands; Male; Manometry; Motilin; Muscarinic Agonists; Rabbits; Receptors, Gastrointestinal Hormone; Receptors, Neuropeptide; Receptors, Serotonin, 5-HT4; Serotonin Receptor Agonists; Stimulation, Chemical	2007
Mitemcinal (GM-611), an orally active motilin receptor agonist, accelerates colonic motility and bowel movement in conscious dogs. Inflammopharmacology, 2007, Volume: 15, Issue:1 Topics: Administration, Oral; Animals; Colon; Defecation; Diarrhea; Dogs; Dose-Response Relationship, Drug; Erythromycin; Female; Gastrointestinal Motility; Male; Motilin; Muscle Contraction; Receptors, Gastrointestinal Hormone; Receptors, Neuropeptide	2007
Mitemcinal (GM-611), an orally active motilin agonist, facilitates defecation in rabbits and dogs without causing loose stools. Neurogastroenterology and motility, 2007, Volume: 19, Issue:4 Topics: Animals; Constipation; Defecation; Diarrhea; Disease Models, Animal; Dogs; Dose-Response Relationship, Drug; Erythromycin; Gastrointestinal Agents; Morphine; Motilin; Rabbits; Reference Values	2007
Effects of mitemcinal (GM-611), an acid-resistant nonpeptide motilin receptor agonist, on the gastrointestinal contractile activity in conscious dogs. Pharmacology, 2007, Volume: 79, Issue:4 Topics: Administration, Oral; Animals; Digestion; Dogs; Dose-Response Relationship, Drug; Erythromycin; Female; Gastrointestinal Agents; Gastrointestinal Tract; Injections, Intravenous; Male; Motilin; Muscle Contraction; Muscle, Smooth; Receptors, Gastrointestinal Hormone; Receptors, Neuropeptide	2007
Effects of motilin and mitemcinal (GM-611) on gastrointestinal contractile activity in rhesus monkeys in vivo and in vitro. Digestive diseases and sciences, 2007, Volume: 52, Issue:11 Topics: Animals; Binding Sites; Dose-Response Relationship, Drug; Duodenum; Erythromycin; Gastrointestinal Agents; Gastrointestinal Motility; Injections, Intravenous; Macaca mulatta; Male; Motilin; Myoelectric Complex, Migrating; Rabbits; Receptors, Gastrointestinal Hormone; Receptors, Neuropeptide; Stomach	2007
Identification of genes for the ghrelin and motilin receptors and a novel related gene in fish, and stimulation of intestinal motility in zebrafish (Danio rerio) by ghrelin and motilin. General and comparative endocrinology, 2008, Jan-01, Volume: 155, Issue:1 Topics: Amino Acid Sequence; Animals; Cloning, Molecular; Electric Stimulation; Erythromycin; Female; Fishes; Gastrointestinal Motility; Ghrelin; Humans; Male; Molecular Sequence Data; Motilin; Phylogeny; Receptors, Gastrointestinal Hormone; Receptors, Ghrelin; Receptors, Neuropeptide; Sequence Homology; Zebrafish	2008
Expression of motilin in the hypothalamus and the effect of central erythromycin on gastric motility in diabetic rats. Neuroscience bulletin, 2007, Volume: 23, Issue:2 Topics: Animals; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Erythromycin; Gastrointestinal Agents; Gastrointestinal Motility; Hippocampus; Injections, Intraventricular; Male; Microinjections; Motilin; Neurons; Paraventricular Hypothalamic Nucleus; Rats; Rats, Sprague-Dawley; Receptors, Gastrointestinal Hormone; Receptors, Neuropeptide; Statistics, Nonparametric; Supraoptic Nucleus	2007
Distribution and electrophysiological effects of motilin in Purkinje cells. Neuroreport, 2007, Aug-27, Volume: 18, Issue:13 Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Animals, Newborn; Cerebellum; Erythromycin; Excitatory Amino Acid Antagonists; Gastrointestinal Agents; Humans; In Vitro Techniques; Motilin; Patch-Clamp Techniques; Purkinje Cells; Rats; Rats, Sprague-Dawley; Receptors, Gastrointestinal Hormone; Receptors, Neuropeptide	2007
Differences in motilin receptor desensitization after stimulation with motilin or motilides are due to alternative receptor trafficking. Biochemical pharmacology, 2008, Mar-01, Volume: 75, Issue:5 Topics: Animals; Arrestins; beta-Arrestin 1; beta-Arrestin 2; beta-Arrestins; CHO Cells; Cricetinae; Cricetulus; Erythromycin; Humans; Motilin; Phosphorylation; Protein Transport; Receptors, Gastrointestinal Hormone; Receptors, Neuropeptide; Transfection	2008
Changes in gallbladder volume in healthy dogs after food was withheld for 12 hours followed by ingestion of a meal or a meal containing erythromycin. American journal of veterinary research, 2008, Volume: 69, Issue:5 Topics: Animals; Dogs; Eating; Erythromycin; Fasting; Female; Gallbladder; Gastrointestinal Agents; Male; Motilin; Muscle Contraction; Statistics, Nonparametric; Ultrasonography	2008
GSK962040: a small molecule, selective motilin receptor agonist, effective as a stimulant of human and rabbit gastrointestinal motility. Neurogastroenterology and motility, 2009, Volume: 21, Issue:6 Topics: Animals; Defecation; Electric Stimulation; Erythromycin; Gallbladder Emptying; Gastrointestinal Motility; Humans; In Vitro Techniques; Male; Motilin; Parasympathetic Nervous System; Piperazines; Piperidines; Pyloric Antrum; Rabbits; Receptors, Gastrointestinal Hormone; Receptors, Neuropeptide; Recombinant Proteins; Stimulation, Chemical; Substrate Specificity	2009
Structure-activity relationships of 9-substituted-9-dihydroerythromycin-based motilin agonists: optimizing for potency and safety. Journal of medicinal chemistry, 2009, Nov-12, Volume: 52, Issue:21 Topics: Animals; Bacteria; Cell Line; ERG1 Potassium Channel; Erythromycin; Ether-A-Go-Go Potassium Channels; Gastrointestinal Agents; Humans; In Vitro Techniques; Intestines; Microbial Sensitivity Tests; Motilin; Muscle Contraction; Muscle, Smooth; Rabbits; Stereoisomerism; Structure-Activity Relationship; Tachyphylaxis	2009
Physiological characteristics of gastric contractions and circadian gastric motility in the free-moving conscious house musk shrew (Suncus murinus). American journal of physiology. Regulatory, integrative and comparative physiology, 2010, Volume: 299, Issue:4 Topics: Animals; Atropine; Behavior, Animal; Body Weight; Eating; Erythromycin; Fasting; Gastrointestinal Motility; Male; Monitoring, Physiologic; Motilin; Postprandial Period; Protein Synthesis Inhibitors; Shrews; Stomach	2010
9-Dihydroerythromycin ethers as motilin agonists--developing structure-activity relationships for potency and safety. Bioorganic & medicinal chemistry, 2010, Nov-01, Volume: 18, Issue:21 Topics: Anti-Bacterial Agents; ERG1 Potassium Channel; Erythromycin; Ether-A-Go-Go Potassium Channels; Ethers; Humans; Microbial Sensitivity Tests; Motilin; Structure-Activity Relationship	2010
The role of the 4''-hydroxyl on motilin agonist potency in the 9-dihydroerythromycin series. Bioorganic & medicinal chemistry letters, 2011, Jun-15, Volume: 21, Issue:12 Topics: Cells, Cultured; ERG1 Potassium Channel; Erythromycin; Ether-A-Go-Go Potassium Channels; Gastrointestinal Agents; Humans; Hydroxyl Radical; Inhibitory Concentration 50; Molecular Structure; Motilin	2011
A relationship between motilin and growth hormone secretagogue receptors. Regulatory peptides, 2012, Jun-10, Volume: 176, Issue:1-3 Topics: Animals; Erythromycin; Ghrelin; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Motilin; Receptors, Gastrointestinal Hormone; Receptors, Ghrelin; Receptors, Neuropeptide	2012
Motilin: towards a new understanding of the gastrointestinal neuropharmacology and therapeutic use of motilin receptor agonists. British journal of pharmacology, 2013, Volume: 170, Issue:7 Topics: Animals; Drug Design; Enteric Nervous System; Erythromycin; Gastrointestinal Agents; Gastrointestinal Diseases; Gastrointestinal Motility; Gastrointestinal Tract; Humans; Motilin; Neurotransmitter Agents; Receptors, Gastrointestinal Hormone; Receptors, Neuropeptide; Signal Transduction	2013
The antibiotic azithromycin is a motilin receptor agonist in human stomach: comparison with erythromycin. British journal of pharmacology, 2013, Volume: 168, Issue:8 Topics: Adult; Aged; Aged, 80 and over; Animals; Anti-Bacterial Agents; Azithromycin; Calcium; CHO Cells; Cricetulus; Electric Stimulation; Erythromycin; Female; Gastrointestinal Agents; Gastrointestinal Motility; Humans; Male; Middle Aged; Motilin; Obesity; Pyloric Antrum; Receptors, Gastrointestinal Hormone; Receptors, Neuropeptide; Recombinant Proteins	2013
Anti-emetic and emetic effects of erythromycin in Suncus murinus: role of vagal nerve activation, gastric motility stimulation and motilin receptors. European journal of pharmacology, 2013, Jan-15, Volume: 699, Issue:1-3 Topics: Animals; Antiemetics; Disease Models, Animal; Dose-Response Relationship, Drug; Electric Stimulation; Erythromycin; Female; Gastric Mucosa; Gastrointestinal Agents; Gastrointestinal Motility; Male; Motilin; Muscle Contraction; Nicotine; Receptors, Gastrointestinal Hormone; Receptors, Neuropeptide; Shrews; Stomach; Vagus Nerve; Vomiting	2013
Motilin-induced gastric contractions signal hunger in man. Gut, 2016, Volume: 65, Issue:2 Topics: Appetite; Cholinesterase Inhibitors; Duodenum; Eating; Erythromycin; Gastrointestinal Motility; Ghrelin; Humans; Hunger; Manometry; Motilin; Muscle Contraction; Myoelectric Complex, Migrating; Neostigmine; Octreotide; Peptide Fragments; Somatostatin; Stomach	2016
Higher plasma motilin levels in obese patients decrease after Roux-en-Y gastric bypass surgery and regulate hunger. Gut, 2016, Volume: 65, Issue:7 Topics: Adult; Case-Control Studies; Duodenum; Erythromycin; Female; Gastric Bypass; Gastrointestinal Agents; Ghrelin; Humans; Hunger; Male; Motilin; Myoelectric Complex, Migrating; Obesity; Postoperative Period; Preoperative Period; Pyloric Antrum; Surveys and Questionnaires	2016
Characterization of the gastric motility response to human motilin and erythromycin in human motilin receptor-expressing transgenic mice. PloS one, 2019, Volume: 14, Issue:2 Topics: Animals; Calcium; Cations, Divalent; Cholinergic Neurons; Erythromycin; Gastrointestinal Motility; Gene Expression; Humans; Male; Mice, Inbred C57BL; Mice, Transgenic; Motilin; Muscle Contraction; Muscle, Smooth; Myenteric Plexus; Receptors, Gastrointestinal Hormone; Receptors, Neuropeptide; Stomach; Tissue Culture Techniques	2019
Structural basis for motilin and erythromycin recognition by motilin receptor. Science advances, 2023, 03-17, Volume: 9, Issue:11 Topics: Erythromycin; Humans; Motilin; Receptors, Gastrointestinal Hormone; Receptors, Neuropeptide	2023
Discovery of N-(3-fluorophenyl)-1-[(4-([(3S)-3-methyl-1-piperazinyl]methyl)phenyl)acetyl]-4-piperidinamine (GSK962040), the first small molecule motilin receptor agonist clinical candidate. Journal of medicinal chemistry, 2009, Feb-26, Volume: 52, Issue:4 Topics: Animals; Dogs; Drug Discovery; Gastrointestinal Agents; Gastrointestinal Motility; Humans; Muscle Contraction; Piperazines; Piperidines; Pyloric Antrum; Rabbits; Rats; Receptors, Gastrointestinal Hormone; Receptors, Neuropeptide	2009