erythromycin has been researched along with mitemcinal in 23 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (13.04) | 18.2507 |
| 2000's | 20 (86.96) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Abdullah, NA; Chen, S; Inoue, R; Ito, Y; Tanaka, M; Yamada, K | 1 |
| Kitazawa, T; Ohga, A; Taneike, T | 1 |
| Bertrand, PP; Bornstein, JC; Clark, MJ; Furness, JB; Jenkinson, KM; Verlinden, M; Wright, T | 1 |
| Miller, P; Poitras, P; St-Pierre, S; Takanashi, H; Trudel, L | 1 |
| Peeters, TL | 1 |
| Itoh, Z; Koga, H; Omura, S; Ozaki, K; Takanashi, H; Yogo, K | 1 |
| Itoh, Z; Kamei, K; Koga, H; Muramatsu, H; Omura, S; Ozaki, K; Sudo, H; Takanashi, H; Yogo, K | 1 |
| Cynshi, O; Itoh, Z; Kamei, K; Koga, H; Muramatsu, H; Omura, S; Ozaki, K; Sudo, H; Takanashi, H; Yogo, K | 1 |
| Akima, M; Itoh, Z; Kamei, K; Koga, H; Omura, S; Onoma, M; Ozaki, K; Sudo, H; Takanashi, H; Yogo, K | 1 |
| Itoh, Z; Koto, M; Omura, S; Ozaki, K; Takanashi, H; Yogo, K | 1 |
| Itoh, M; Itoh, Z; Kato, A; Kimura, K; Mizoguchi, K; Omura, S; Suzuki, M; Tabo, M; Takanashi, H | 1 |
| Itoh, Z; Kato, A; Kimura, K; Mizoguchi, K; Omura, S; Suzuki, M; Tabo, M; Takanashi, H | 1 |
| Cynshi, O; McCallum, RW | 1 |
| Akiba, Y; Aso, Y; Higashida, A; Itoh, Z; Kawanishi, T; Mitsui, T; Miyayama, T; Omura, S; Saitoh, R; Takata, S | 1 |
| Itoh, Z; Koto, M; Omura, S; Onoma, M; Ozaki, K; Takanashi, H; Yogo, K | 1 |
| Akima, M; Itoh, Z; Kamei, K; Koga, H; Omura, S; Onoma, M; Ozaki, K; Takanashi, H; Yogo, K | 1 |
| Yang, Y | 1 |
| Hayashi, S; Itoh, Z; Kamei, K; Kawabe, Y; Matsuo, S; Monnai, M; Muramatsu, H; Omura, S; Onoma, M; Ozaki, K; Shiga, T; Suzuki, M; Takanashi, H; Yogo, K | 1 |
| Fujii, E; Itoh, Z; Kato, A; Kimura, K; Mizoguchi, K; Omura, S; Suzuki, M; Takanashi, H | 1 |
| Fujii, E; Hayashi, S; Itoh, Z; Kato, A; Kimura, K; Mizoguchi, K; Omura, S; Sugimoto, T; Suzuki, M; Takanashi, H; Wanibuchi, H | 1 |
| Kamada, K; Murata, H; Murata, M; Nagai, H; Terada, K; Ushio, H; Yoshimura, S | 1 |
| Cynshi, O; Takanashi, H | 1 |
| Hagane, K; Hirabayashi, T; Hoshino, K; Matsufuji, H; Morikawa, Y; Ozaki, K | 1 |
3 review(s) available for erythromycin and mitemcinal
| Article | Year |
|---|---|
GM-611 (Chugai Pharmaceutical).
Topics: Animals; Clinical Trials as Topic; Erythromycin; Gastrointestinal Motility; Humans; Receptors, Gastrointestinal Hormone; Receptors, Neuropeptide; Structure-Activity Relationship | 2001 |
[Mechanism and clinical application of erythromycin as a gastrointestinal prokinetic agent in children].
Topics: Anti-Bacterial Agents; Child; Dyspepsia; Erythromycin; Gastroesophageal Reflux; Gastrointestinal Motility; Humans; Motilin; Receptors, Gastrointestinal Hormone; Receptors, Neuropeptide | 2008 |
Motilides: a long and winding road: lessons from mitemcinal (GM-611) on diabetic gastroparesis.
Topics: Animals; Diabetes Complications; Dogs; Erythromycin; Gastric Emptying; Gastrointestinal Agents; Gastroparesis; Humans; Molecular Structure; Randomized Controlled Trials as Topic | 2009 |
1 trial(s) available for erythromycin and mitemcinal
| Article | Year |
|---|---|
Clinical trial: effect of mitemcinal (a motilin agonist) on gastric emptying in patients with gastroparesis - a randomized, multicentre, placebo-controlled study.
Topics: Adolescent; Adult; Aged; Blood Glucose; Diabetes Mellitus; Dose-Response Relationship, Drug; Double-Blind Method; Erythromycin; Female; Gastric Emptying; Gastrointestinal Agents; Gastroparesis; Humans; Male; Middle Aged; Motilin; Placebos; Treatment Outcome | 2007 |
19 other study(ies) available for erythromycin and mitemcinal
| Article | Year |
|---|---|
Electrophysiological characterization of a motilin agonist, GM611, on rabbit duodenal smooth muscle.
Topics: Animals; Duodenum; Erythromycin; Gastrointestinal Agents; Male; Motilin; Muscle Contraction; Muscle, Smooth; Patch-Clamp Techniques; Rabbits | 1996 |
Functional characterization of neural and smooth muscle motilin receptors in the chicken proventriculus and ileum.
Topics: Animals; Chickens; Dogs; Erythromycin; Gastrointestinal Agents; Hormones; Ileum; Motilin; Muscle Contraction; Muscle, Smooth; Proventriculus; Rabbits; Receptors, Gastrointestinal Hormone; Receptors, Neuropeptide; Swine | 1997 |
Erythromycin derivatives ABT 229 and GM 611 act on motilin receptors in the rabbit duodenum.
Topics: Animals; Anti-Bacterial Agents; Carbachol; Dose-Response Relationship, Drug; Duodenum; Erythromycin; Female; Gastrointestinal Agents; Male; Motilin; Muscle Contraction; Rabbits; Receptors, Gastrointestinal Hormone; Receptors, Neuropeptide | 1999 |
Neural and muscular receptors for motilin in the rabbit colon.
Topics: Animals; Binding, Competitive; Colon; Duodenum; Erythromycin; Female; Gastrointestinal Motility; Hormone Antagonists; Iodine Radioisotopes; Motilin; Muscle, Smooth; Peptides, Cyclic; Rabbits; Receptors, Gastrointestinal Hormone; Receptors, Neuropeptide; Synaptosomes | 2000 |
In vitro pharmacological characterization of mitemcinal (GM-611), the first acid-resistant non-peptide motilin receptor agonist, in smooth muscle of rabbit small intestine.
Topics: Acetylcholine; Animals; Atropine; Binding, Competitive; Calcium Chloride; Diltiazem; Dose-Response Relationship, Drug; Erythromycin; Hexamethonium; Hydrogen-Ion Concentration; In Vitro Techniques; Indoles; Intestine, Small; Male; Molecular Structure; Muscle Contraction; Muscle, Smooth; Naloxone; Rabbits; Receptors, Gastrointestinal Hormone; Receptors, Neuropeptide; Tetrodotoxin; Tropisetron; Verapamil | 2007 |
Mitemcinal (GM-611), an orally active motilin receptor agonist, accelerates colonic motility and bowel movement in conscious dogs.
Topics: Administration, Oral; Animals; Colon; Defecation; Diarrhea; Dogs; Dose-Response Relationship, Drug; Erythromycin; Female; Gastrointestinal Motility; Male; Motilin; Muscle Contraction; Receptors, Gastrointestinal Hormone; Receptors, Neuropeptide | 2007 |
Mitemcinal (GM-611), an orally active motilin agonist, facilitates defecation in rabbits and dogs without causing loose stools.
Topics: Animals; Constipation; Defecation; Diarrhea; Disease Models, Animal; Dogs; Dose-Response Relationship, Drug; Erythromycin; Gastrointestinal Agents; Morphine; Motilin; Rabbits; Reference Values | 2007 |
Effects of mitemcinal (GM-611), an acid-resistant nonpeptide motilin receptor agonist, on the gastrointestinal contractile activity in conscious dogs.
Topics: Administration, Oral; Animals; Digestion; Dogs; Dose-Response Relationship, Drug; Erythromycin; Female; Gastrointestinal Agents; Gastrointestinal Tract; Injections, Intravenous; Male; Motilin; Muscle Contraction; Muscle, Smooth; Receptors, Gastrointestinal Hormone; Receptors, Neuropeptide | 2007 |
Effects of motilin and mitemcinal (GM-611) on gastrointestinal contractile activity in rhesus monkeys in vivo and in vitro.
Topics: Animals; Binding Sites; Dose-Response Relationship, Drug; Duodenum; Erythromycin; Gastrointestinal Agents; Gastrointestinal Motility; Injections, Intravenous; Macaca mulatta; Male; Motilin; Myoelectric Complex, Migrating; Rabbits; Receptors, Gastrointestinal Hormone; Receptors, Neuropeptide; Stomach | 2007 |
Preclinical electrophysiology assays of mitemcinal (GM-611), a novel prokinetic agent derived from erythromycin.
Topics: Action Potentials; Animals; Cell Line; Cisapride; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Electrocardiography; ERG1 Potassium Channel; Erythromycin; Ether-A-Go-Go Potassium Channels; Gastrointestinal Agents; Gastrointestinal Motility; Guinea Pigs; Heart Atria; Heart Conduction System; Heart Rate; Humans; Long QT Syndrome; Male; Potassium Channel Blockers; Rabbits; Risk Assessment; Time Factors; Torsades de Pointes; Transfection | 2007 |
Hemodynamic and electrophysiological effects of mitemcinal (GM-611), a novel prokinetic agent derived from erythromycin in a halothane-anesthetized canine model.
Topics: Action Potentials; Anesthesia, General; Anesthetics, Inhalation; Animals; Blood Pressure; Cardiac Pacing, Artificial; Cisapride; Dogs; Dose-Response Relationship, Drug; Electrocardiography; Erythromycin; Gastrointestinal Agents; Gastrointestinal Motility; Halothane; Heart Rate; Infusions, Intravenous; Long QT Syndrome; Male; Models, Animal; Risk Assessment; Time Factors; Torsades de Pointes; Ventricular Function, Left; Ventricular Pressure | 2007 |
Nonlinear intestinal pharmacokinetics of mitemcinal, the first acid-resistant non-peptide motilin receptor agonist, in rats.
Topics: Administration, Oral; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Bile; Caco-2 Cells; Cell Membrane Permeability; Digoxin; Dose-Response Relationship, Drug; Erythromycin; Humans; Intestinal Absorption; Intestinal Mucosa; Male; Rats; Rats, Sprague-Dawley; Receptors, Gastrointestinal Hormone; Receptors, Neuropeptide | 2007 |
Effects of oral mitemcinal (GM-611), erythromycin, EM-574 and cisapride on gastric emptying in conscious rhesus monkeys.
Topics: Acetaminophen; Administration, Oral; Analgesics, Non-Narcotic; Animals; Cisapride; Consciousness; Erythromycin; Gastric Emptying; Gastrointestinal Agents; Macaca mulatta; Male | 2008 |
Oral mitemcinal (GM-611), an erythromycin-derived prokinetic, accelerates normal and experimentally delayed gastric emptying in conscious dogs.
Topics: Acetaminophen; Administration, Oral; Animals; Cisapride; Clonidine; Disease Models, Animal; Dogs; Dose-Response Relationship, Drug; Duodenum; Erythromycin; Gastric Emptying; Gastric Mucosa; Gastrointestinal Agents; Gastrointestinal Motility; Gastroparesis; Postprandial Period; Receptors, Gastrointestinal Hormone; Receptors, Neuropeptide; Stomach; Time Factors; Vagotomy | 2008 |
Mitemcinal (GM-611), an orally active motilin receptor agonist, improves delayed gastric emptying in a canine model of diabetic gastroparesis.
Topics: Administration, Oral; Animals; Diabetes Mellitus, Experimental; Disease Models, Animal; Dogs; Erythromycin; Female; Gastric Emptying; Gastroparesis; Receptors, Gastrointestinal Hormone; Receptors, Neuropeptide | 2008 |
Assessment of the carcinogenic potential of mitemcinal (GM-611): increased incidence of malignant lymphoma in a rat carcinogenicity study.
Topics: Animals; Carcinogenicity Tests; Carcinogens; Cell Line, Tumor; Cell Lineage; Erythromycin; Female; Genes, p53; Immunohistochemistry; Lymphoma; Mice; Mice, Inbred C57BL; Mice, Knockout; Rats; Rats, Sprague-Dawley; Risk Assessment | 2008 |
Characterization of multinuclear hepatocytes induced in rats by mitemcinal (GM-611), an erythromycin derivative.
Topics: Animals; Bromodeoxyuridine; Cell Nucleus; Cell Shape; Dogs; Erythromycin; Female; Hepatocytes; Kinetics; Rats; Rats, Sprague-Dawley | 2008 |
Characterization and monitoring of pseudo-polymorphs in manufacturing process by NIR.
Topics: Chemistry, Pharmaceutical; Crystallization; Drug Stability; Erythromycin; Humidity; Spectroscopy, Near-Infrared; Tablets; X-Ray Diffraction | 2009 |
Stimulatory action of mitemcinal (GM-611), an acid-resistant non-peptide motilin receptor agonist, on colonic motor activity and defecation: spontaneous and mitemcinal-induced giant migrating contractions during defecation in dogs.
Topics: Animals; Anthraquinones; Circadian Rhythm; Colon; Defecation; Dogs; Erythromycin; Female; Gastrointestinal Motility; Laxatives; Muscle, Smooth; Myoelectric Complex, Migrating; Receptors, Gastrointestinal Hormone; Receptors, Neuropeptide; Senna Extract; Sennosides; Transducers | 2009 |