erythromycin has been researched along with methylmalonyl-coenzyme a in 18 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (5.56) | 18.7374 |
| 1990's | 8 (44.44) | 18.2507 |
| 2000's | 6 (33.33) | 29.6817 |
| 2010's | 2 (11.11) | 24.3611 |
| 2020's | 1 (5.56) | 2.80 |
| Authors | Studies |
|---|---|
| Hunaiti, AA; Kolattukudy, PE | 1 |
| Kao, CM; Katz, L; Khosla, C | 1 |
| Cane, DE | 1 |
| Aparicio, JF; Caffrey, P; Leadlay, PF; Loughran, MS; Marsden, AF; Staunton, J | 1 |
| Leadlay, PF; Roberts, GA; Staunton, J | 1 |
| Cane, D; Ebert-Khosla, S; Khosla, C; Pieper, R | 1 |
| Donadio, S; Jackson, M; Kakavas, S; Katz, L; Pereda, A; Ruan, X; Shivakumar, A; Stassi, DL; Staver, MJ; Summers, RG; Zeidner, D | 1 |
| Bycroft, M; Grice, P; Hanefeld, U; Leadlay, PF; Staunton, J; Timoney, M; Weissman, KJ | 1 |
| Cane, DE; Fu, H; Khosla, C; Lau, J | 1 |
| Admiraal, SJ; Cane, DE; Gramajo, H; Khosla, C; Pfeifer, BA | 1 |
| Ferber, D | 1 |
| Carney, JR; Dayem, LC; Kealey, JT; Kennedy, J; Murli, S | 1 |
| Kealey, JT; Kennedy, J; Murli, S | 1 |
| Brikun, IA; Cernota, WH; Reeves, AR; Weber, JM; Wesley, RK | 1 |
| Brikun, IA; Cernota, WH; Gonzalez, MC; Leach, BI; Reeves, AR; Weber, JM | 1 |
| Boghigian, BA; Pfeifer, BA; Zhang, H | 1 |
| Jiang, M; Pfeifer, BA | 1 |
| Chen, K; Chen, Y; Khan, S; Li, B; Ren, S; Wu, H; Wu, P; Zhang, B; Zhang, L; Zhang, Y | 1 |
18 other study(ies) available for erythromycin and methylmalonyl-coenzyme a
| Article | Year |
|---|---|
Source of methylmalonyl-coenzyme A for erythromycin synthesis: methylmalonyl-coenzyme A mutase from Streptomyces erythreus.
Topics: Acyl Coenzyme A; Bacterial Proteins; Chromatography, DEAE-Cellulose; Erythromycin; Hydrogen-Ion Concentration; Isomerases; Kinetics; Malonyl Coenzyme A; Methylmalonyl-CoA Mutase; Streptomyces; Vitamin B 12 | 1984 |
Engineered biosynthesis of a complete macrolactone in a heterologous host.
Topics: Acyl Coenzyme A; Base Sequence; Binding Sites; Cloning, Molecular; Drug Design; Erythromycin; Escherichia coli; Genes, Bacterial; Genetic Engineering; Genetic Vectors; Molecular Sequence Data; Multienzyme Complexes; Multigene Family; Mutation; Oleandomycin; Recombinant Proteins; Streptomyces; Structure-Activity Relationship | 1994 |
Polyketide biosynthesis: molecular recognition or genetic programming?
Topics: Acetyl Coenzyme A; Acyl Coenzyme A; Anthraquinones; Anti-Bacterial Agents; Cell-Free System; Erythromycin; Malonyl Coenzyme A; Multienzyme Complexes; Naphthacenes; Streptomyces | 1994 |
Stereospecific acyl transfers on the erythromycin-producing polyketide synthase.
Topics: Acetyl Coenzyme A; Acyl Coenzyme A; Erythromycin; Malonyl Coenzyme A; Molecular Conformation; Multienzyme Complexes; Racemases and Epimerases; Saccharopolyspora; Stereoisomerism; Substrate Specificity | 1994 |
Heterologous expression in Escherichia coli of an intact multienzyme component of the erythromycin-producing polyketide synthase.
Topics: Acyl Coenzyme A; Amino Acid Sequence; Base Sequence; Binding Sites; Chromatography, Gel; DNA, Bacterial; Erythromycin; Escherichia coli; Gene Expression; Genes, Bacterial; Genetic Engineering; Molecular Sequence Data; Molecular Weight; Multienzyme Complexes; Protein Processing, Post-Translational; Recombinant Proteins; Saccharopolyspora | 1993 |
Erythromycin biosynthesis: kinetic studies on a fully active modular polyketide synthase using natural and unnatural substrates.
Topics: Acyl Coenzyme A; Carboxylic Acids; Erythromycin; Kinetics; Multienzyme Complexes; NADP; Phosphates; Streptomyces; Substrate Specificity | 1996 |
Acyltransferase domain substitutions in erythromycin polyketide synthase yield novel erythromycin derivatives.
Topics: Acyl Coenzyme A; Acyltransferases; Amino Acid Sequence; Cloning, Molecular; Erythromycin; Genetic Vectors; Molecular Sequence Data; Molecular Structure; Multienzyme Complexes; Plasmids; Recombinant Proteins; Saccharopolyspora; Transformation, Genetic | 1997 |
The molecular basis of Celmer's rules: the stereochemistry of the condensation step in chain extension on the erythromycin polyketide synthase.
Topics: Acyl Coenzyme A; Catalysis; Deuterium; Erythromycin; Gas Chromatography-Mass Spectrometry; Lactones; Magnetic Resonance Spectroscopy; Multienzyme Complexes; Saccharopolyspora; Solvents; Stereoisomerism; Substrate Specificity | 1997 |
Dissecting the role of acyltransferase domains of modular polyketide synthases in the choice and stereochemical fate of extender units.
Topics: Acyl Coenzyme A; Acyltransferases; Amino Acid Sequence; Erythromycin; Escherichia coli; Isoenzymes; Molecular Sequence Data; Multienzyme Complexes; Plasmids; Protein Processing, Post-Translational; Protein Structure, Tertiary; Recombinant Fusion Proteins; Sirolimus; Stereoisomerism; Streptomyces; Substrate Specificity; Thiolester Hydrolases | 1999 |
Biosynthesis of complex polyketides in a metabolically engineered strain of E. coli.
Topics: Acyl Coenzyme A; Bacterial Proteins; Cloning, Molecular; Erythromycin; Escherichia coli; Multienzyme Complexes; Promoter Regions, Genetic; Recombinant Fusion Proteins; Saccharopolyspora; Transferases (Other Substituted Phosphate Groups); Transformation, Bacterial | 2001 |
Microbiology. Possible new route to polyketide synthesis.
Topics: Acyl Coenzyme A; Bacillus subtilis; Erythromycin; Escherichia coli; Genetic Engineering; Multienzyme Complexes; Pantetheine; Patents as Topic; Protein Engineering; Recombinant Proteins; Saccharopolyspora | 2001 |
Metabolic engineering of Escherichia coli for improved 6-deoxyerythronolide B production.
Topics: Acyl Coenzyme A; Carbon Isotopes; Chromosomes, Bacterial; Erythromycin; Escherichia coli; Gene Expression Regulation, Bacterial; Industrial Microbiology; Intramolecular Transferases; Molecular Biology; Multienzyme Complexes; Plasmids; Propionates | 2003 |
6-Deoxyerythronolide B analogue production in Escherichia coli through metabolic pathway engineering.
Topics: Acetoacetates; Acyl Coenzyme A; Bacterial Proteins; Bacteriocins; Butyrates; DNA Glycosylases; DNA-Binding Proteins; Erythromycin; Escherichia coli; Escherichia coli Proteins; Gene Expression Regulation, Bacterial; Genetic Engineering; Multienzyme Complexes; Peptides; Plasmids; Racemases and Epimerases | 2003 |
Engineering precursor flow for increased erythromycin production in Aeromicrobium erythreum.
Topics: Actinobacteria; Acyl Coenzyme A; Bacterial Proteins; Erythromycin; Gene Deletion; Gene Expression Regulation, Bacterial; Methyltransferases | 2004 |
Engineering of the methylmalonyl-CoA metabolite node of Saccharopolyspora erythraea for increased erythromycin production.
Topics: Acyl Coenzyme A; Bacterial Proteins; Chromosomes, Bacterial; Erythromycin; Genetic Engineering; Open Reading Frames; Saccharopolyspora | 2007 |
Investigating the role of native propionyl-CoA and methylmalonyl-CoA metabolism on heterologous polyketide production in Escherichia coli.
Topics: Acyl Coenzyme A; Coenzyme A-Transferases; Erythromycin; Escherichia coli; Escherichia coli Proteins; Gene Deletion; Gene Dosage; Gene Expression; Macrolides; Methylmalonyl-CoA Decarboxylase; Methylmalonyl-CoA Mutase | 2010 |
Metabolic and pathway engineering to influence native and altered erythromycin production through E. coli.
Topics: Acyl Coenzyme A; Erythromycin; Escherichia coli; Glycerol; Metabolic Engineering | 2013 |
Polyketide Starter and Extender Units Serve as Regulatory Ligands to Coordinate the Biosynthesis of Antibiotics in Actinomycetes.
Topics: Acyl Coenzyme A; Anti-Bacterial Agents; Bacterial Proteins; Biosynthetic Pathways; Erythromycin; Ligands; Polyketide Synthases; Promoter Regions, Genetic; Saccharopolyspora | 2021 |