Page last updated: 2024-08-21

erythromycin and lidocaine

erythromycin has been researched along with lidocaine in 41 studies

Research

Studies (41)

Timeframe	Studies, this research(%)	All Research%
pre-1990	2 (4.88)	18.7374
1990's	9 (21.95)	18.2507
2000's	18 (43.90)	29.6817
2010's	12 (29.27)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Hansch, C; Khwaja, TA; Selassie, CD	1
Huang, L; Humphreys, JE; Morgan, JB; Polli, JW; Serabjit-Singh, CS; Webster, LO; Wring, SA	1
Johans, C; Kinnunen, PK; Söderlund, T; Suomalainen, P	1
Jolivette, LJ; Ward, KW	1
Jolivette, LJ; Nagilla, R; Ward, KW	1
Abraham, MH; Acree, WE; Ibrahim, A	1
Lombardo, F; Obach, RS; Waters, NJ	1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM	1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM	1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Glen, RC; Lowe, R; Mitchell, JB	1
Ekins, S; Williams, AJ; Xu, JJ	1
Balko, KM; Colby, DA; Mo, H	1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K	1
Giacomini, KM; Huang, Y; Khuri, N; Kido, Y; Kosaka, A; Morrissey, KM; Sali, A; Wittwer, MB; Zhang, X; Zur, AA	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Bellman, K; Knegtel, RM; Settimo, L	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Deu, C; Guerin, C; Gueugniaud, PY; Mahul, P; Robert, D	1
D'Arcy, PF	1
Cakaloglu, Y; Devlin, J; Tredger, JM; Williams, R	1
Bruschetta, HR; Guzman, E; Niarchos, AP; Parente, TF; Paris, DG	1
Watkins, PB	1
Alworth, WL; Foroozesh, M; Halpert, JR; Hollenberg, PF; Hopkins, NE; Roberts, ES	1
Tanaka, E; Yasuhara, H	1
Isohanni, MH; Neuvonen, PJ; Olkkola, KT; Palkama, VJ	1
Isohanni, MH; Neuvonen, PJ; Olkkola, KT	2
Backman, JT; Kivistö, KT; Neuvonen, PJ; Taavitsainen, P; Wang, JS; Wen, X	1
Nieto, JE; Rakestraw, PC; Snyder, JR; Vatistas, NJ	1
Danhof, M; Groeneveld, AB; Swart, EL; Touw, DJ; van der Hoven, B	1
De Martin, S; Orlando, R; Padrini, R; Palatini, P; Piccoli, P	1
Hamunen, K; Isohanni, MH; Neuvonen, PJ; Olkkola, KT	1
Cripps, PJ; Dallap, BL; Edwards, GB; Proudman, CJ; Smith, MA	1
Bhadresa, S; Coon, DJ; Lawrence, MS; Magiera, D; Struharik, M; Ward, KW	1
Abouei Mehrizi, A; Fathollahipour, S; Ghaee, A; Koosha, M	1

Reviews

4 review(s) available for erythromycin and lidocaine

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Torsades de pointes induced by erythromycin and terfenadine. The American journal of emergency medicine, 1994, Volume: 12, Issue:6 Topics: Drug Therapy, Combination; Electrocardiography; Erythromycin; Female; Humans; Lidocaine; Magnesium; Middle Aged; Terfenadine; Torsades de Pointes	1994
Noninvasive tests of CYP3A enzymes. Pharmacogenetics, 1994, Volume: 4, Issue:4 Topics: Animals; Breath Tests; Cytochrome P-450 Enzyme System; Dapsone; Erythromycin; Humans; Hydrocortisone; Lidocaine; Liver; Midazolam; Nifedipine	1994
[Evaluation of liver function in liver diseases using drugs as indicators]. The Journal of toxicological sciences, 1997, Volume: 22, Issue:3 Topics: Aminopyrine; Antipyrine; Erythromycin; Humans; Lidocaine; Liver; Liver Diseases; Liver Function Tests; Trimethadione	1997

Trials

6 trial(s) available for erythromycin and lidocaine

Article	Year
Inactivation of cytochrome P450s 2B1, 2B4, 2B6, and 2B11 by arylalkynes. Drug metabolism and disposition: the biological fate of chemicals, 1997, Volume: 25, Issue:11 Topics: Alkynes; Anesthetics, Local; Animals; Anti-Bacterial Agents; Autoradiography; Cytochrome P-450 Enzyme Inhibitors; Dogs; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Erythromycin; Female; Humans; Lidocaine; Male; Mice; Microsomes, Liver; Nitrophenols; Rabbits; Rats; Rats, Inbred F344; Testosterone	1997
Effect of erythromycin and itraconazole on the pharmacokinetics of intravenous lignocaine. European journal of clinical pharmacology, 1998, Volume: 54, Issue:7 Topics: Adult; Anti-Bacterial Agents; Cross-Over Studies; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Double-Blind Method; Drug Interactions; Enzyme Inhibitors; Erythromycin; Female; Humans; Injections, Intravenous; Itraconazole; Lidocaine; Male; Mixed Function Oxygenases	1998
Effect of erythromycin and itraconazole on the pharmacokinetics of oral lignocaine. Pharmacology & toxicology, 1999, Volume: 84, Issue:3 Topics: Administration, Oral; Adult; Anesthetics, Local; Cross-Over Studies; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Double-Blind Method; Drug Interactions; Erythromycin; Female; Humans; Itraconazole; Lidocaine; Male; Mixed Function Oxygenases; Placebos; Protein Synthesis Inhibitors	1999
Effect of the CYP3A4 inhibitor erythromycin on the pharmacokinetics of lignocaine and its pharmacologically active metabolites in subjects with normal and impaired liver function. British journal of clinical pharmacology, 2003, Volume: 55, Issue:1 Topics: Adult; Anesthetics, Local; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Double-Blind Method; Erythromycin; Humans; Lidocaine; Liver Cirrhosis; Male; Protein Synthesis Inhibitors	2003
The effect of erythromycin and fluvoxamine on the pharmacokinetics of intravenous lidocaine. Anesthesia and analgesia, 2005, Volume: 100, Issue:5 Topics: Adult; Cross-Over Studies; Cytochrome P-450 CYP1A2 Inhibitors; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Double-Blind Method; Drug Interactions; Erythromycin; Female; Fluvoxamine; Humans; Infusions, Intravenous; Lidocaine; Male	2005
Effect of fluvoxamine and erythromycin on the pharmacokinetics of oral lidocaine. Basic & clinical pharmacology & toxicology, 2006, Volume: 99, Issue:2 Topics: Administration, Oral; Adult; Anesthetics, Local; Area Under Curve; Cross-Over Studies; Cytochrome P-450 CYP1A2 Inhibitors; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Dose-Response Relationship, Drug; Double-Blind Method; Enzyme Inhibitors; Erythromycin; Female; Fluvoxamine; Half-Life; Humans; Lidocaine; Male; Metabolic Clearance Rate; Nausea	2006

Other Studies

31 other study(ies) available for erythromycin and lidocaine

Article	Year
Structure-activity relationships of antineoplastic agents in multidrug resistance. Journal of medicinal chemistry, 1990, Volume: 33, Issue:7 Topics: Animals; Antineoplastic Agents; Cell Line; Cell Survival; Cricetinae; Dactinomycin; Drug Resistance; Leukemia L1210; Mice; Regression Analysis; Structure-Activity Relationship; Tumor Cells, Cultured	1990
Rational use of in vitro P-glycoprotein assays in drug discovery. The Journal of pharmacology and experimental therapeutics, 2001, Volume: 299, Issue:2 Topics: Adenosine Triphosphatases; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cells, Cultured; Chromatography, Liquid; Enzyme Inhibitors; Fluoresceins; Fluorescent Dyes; Humans; Mass Spectrometry; Pharmacology; Spodoptera	2001
Surface activity profiling of drugs applied to the prediction of blood-brain barrier permeability. Journal of medicinal chemistry, 2004, Mar-25, Volume: 47, Issue:7 Topics: Blood-Brain Barrier; Lipid Bilayers; Micelles; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship; Surface Properties	2004
Extrapolation of human pharmacokinetic parameters from rat, dog, and monkey data: Molecular properties associated with extrapolative success or failure. Journal of pharmaceutical sciences, 2005, Volume: 94, Issue:7 Topics: Algorithms; Animals; Dogs; Haplorhini; Humans; Pharmaceutical Preparations; Pharmacokinetics; Rats; Species Specificity; Tissue Distribution	2005
Comparative evaluation of oral systemic exposure of 56 xenobiotics in rat, dog, monkey and human. Xenobiotica; the fate of foreign compounds in biological systems, 2005, Volume: 35, Issue:2 Topics: Administration, Oral; Animals; Area Under Curve; Dogs; Haplorhini; Humans; Models, Statistical; Rats; Software; Species Specificity; Xenobiotics	2005
Air to lung partition coefficients for volatile organic compounds and blood to lung partition coefficients for volatile organic compounds and drugs. European journal of medicinal chemistry, 2008, Volume: 43, Issue:3 Topics: Air; Animals; Humans; Lung; Organic Chemicals; Probability; Rats; Tissue Distribution; Volatilization	2008
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19 Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship	2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21 Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain. Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19 Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models. Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3 Topics:	2008
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species. Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6 Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
Predicting phospholipidosis using machine learning. Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5 Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
A practical deuterium-free NMR method for the rapid determination of 1-octanol/water partition coefficients of pharmaceutical agents. Bioorganic & medicinal chemistry letters, 2010, Nov-15, Volume: 20, Issue:22 Topics: 1-Octanol; Magnetic Resonance Spectroscopy; Pharmaceutical Preparations; Water	2010
QSAR-based permeability model for drug-like compounds. Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8 Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2011
Discovery of potent, selective multidrug and toxin extrusion transporter 1 (MATE1, SLC47A1) inhibitors through prescription drug profiling and computational modeling. Journal of medicinal chemistry, 2013, Feb-14, Volume: 56, Issue:3 Topics: Computer Simulation; Fluorescent Dyes; Organic Cation Transport Proteins; Prescription Drugs	2013
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds. Pharmaceutical research, 2014, Volume: 31, Issue:4 Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation	2014
[Torsade de pointes induced by the combination lidocaine-erythromycin and hepatic insufficiency]. Presse medicale (Paris, France : 1983), 1985, Apr-20, Volume: 14, Issue:16 Topics: Aged; Drug Therapy, Combination; Erythromycin; Humans; Lidocaine; Liver Diseases; Male; Tachycardia	1985
Early reports on drug interactions. Drug intelligence & clinical pharmacy, 1983, Volume: 17, Issue:2 Topics: Acetaminophen; Amiodarone; Apazone; Aspirin; Carbamazepine; Chlordiazepoxide; Cimetidine; Coumarins; Drug Interactions; Erythromycin; Ethanol; Furosemide; Gentamicins; Humans; Levodopa; Lidocaine; Phenytoin; Prenylamine; Quinidine	1983
Importance of cytochrome P-450IIIA activity in determining dosage and blood levels of FK 506 and cyclosporine in liver transplant recipients. Hepatology (Baltimore, Md.), 1994, Volume: 20, Issue:2 Topics: Aryl Hydrocarbon Hydroxylases; Breath Tests; Cyclosporine; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Erythromycin; Female; Humans; Lidocaine; Liver Transplantation; Male; Oxidoreductases, N-Demethylating; Predictive Value of Tests; Regression Analysis; Tacrolimus	1994
Fluvoxamine is a more potent inhibitor of lidocaine metabolism than ketoconazole and erythromycin in vitro. Pharmacology & toxicology, 1999, Volume: 85, Issue:5 Topics: Anesthetics, Local; Autopsy; Cytochrome P-450 CYP1A2 Inhibitors; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Dose-Response Relationship, Drug; Enzyme Inhibitors; Erythromycin; Fluvoxamine; Humans; In Vitro Techniques; Ketoconazole; Lidocaine; Male; Microsomes, Liver; Middle Aged; Mixed Function Oxygenases	1999
In vitro effects of erythromycin, lidocaine, and metoclopramide on smooth muscle from the pyloric antrum, proximal portion of the duodenum, and middle portion of the jejunum of horses. American journal of veterinary research, 2000, Volume: 61, Issue:4 Topics: Animals; Anti-Arrhythmia Agents; Dopamine Antagonists; Duodenum; Erythromycin; Gastrointestinal Agents; Horse Diseases; Horses; In Vitro Techniques; Intestinal Obstruction; Jejunum; Lidocaine; Metoclopramide; Muscle Contraction; Muscle, Smooth; Postoperative Complications; Pyloric Antrum	2000
Correlation between midazolam and lignocaine pharmacokinetics and MEGX formation in healthy volunteers. British journal of clinical pharmacology, 2002, Volume: 53, Issue:2 Topics: Adult; Drug Interactions; Erythromycin; Female; Humans; Hypnotics and Sedatives; Lidocaine; Liver Function Tests; Male; Midazolam; Time Factors	2002
Evaluation of the clinical efficacy of prokinetic drugs in the management of post-operative ileus: can retrospective data help us? Veterinary journal (London, England : 1997), 2005, Volume: 170, Issue:2 Topics: Animals; Cisapride; Digestive System Surgical Procedures; Erythromycin; Gastrointestinal Agents; Horse Diseases; Horses; Ileus; Lidocaine; Metoclopramide; Retrospective Studies; Risk Factors	2005
Exploration of the African green monkey as a preclinical pharmacokinetic model: oral pharmacokinetic parameters and drug-drug interactions. Xenobiotica; the fate of foreign compounds in biological systems, 2009, Volume: 39, Issue:3 Topics: Animals; Aza Compounds; Chlorocebus aethiops; Chromatography, High Pressure Liquid; Ciprofloxacin; Drug Evaluation, Preclinical; Erythromycin; Fluoroquinolones; Lidocaine; Mass Spectrometry; Models, Animal; Moxifloxacin; Pharmacokinetics; Phenytoin; Prednisolone; Propranolol; Quinolines; Species Specificity	2009
Electrospinning of PVA/chitosan nanocomposite nanofibers containing gelatin nanoparticles as a dual drug delivery system. Journal of biomedical materials research. Part A, 2015, Volume: 103, Issue:12 Topics: Anesthetics, Local; Anti-Bacterial Agents; Bandages; Chitosan; Drug Delivery Systems; Erythromycin; Gelatin; Lidocaine; Nanocomposites; Nanofibers; Nanoparticles; Polyvinyl Alcohol	2015