Page last updated: 2024-08-21

erythromycin and itraconazole

erythromycin has been researched along with itraconazole in 25 studies

Research

Studies (25)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	7 (28.00)	18.2507
2000's	9 (36.00)	29.6817
2010's	7 (28.00)	24.3611
2020's	2 (8.00)	2.80

Authors

Authors	Studies
Huang, L; Humphreys, JE; Morgan, JB; Polli, JW; Serabjit-Singh, CS; Webster, LO; Wring, SA	1
Fischer, H; Huwyler, J; Poli, S; Schwab, D; Tabatabaei, A	1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Ekins, S; Harwood, HJ; Hoover, DJ; Lawton, MP; Mankowski, DC; Treadway, JL	1
Andricopulo, AD; Moda, TL; Montanari, CA	1
Lombardo, F; Obach, RS; Waters, NJ	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Gao, F; Huang, G; Xiao, J	1
Oster, G; Thompson, D	1
Kantola, T; Kivistö, KT; Lamberg, TS; Neuvonen, PJ	1
Barbanoj, MJ; Jané, F; Parra, P	1
Isohanni, MH; Neuvonen, PJ; Olkkola, KT; Palkama, VJ	1
Isohanni, MH; Neuvonen, PJ; Olkkola, KT	1
Brosen, K; Damkier, P; Hansen, LL	1
Iga, T; Katashima, M; Kotaki, H; Matsuo, H; Ohtani, H; Sawada, Y; Takedomi, S; Yamamoto, K; Yamano, K	1
Ghoos, Y; Lemahieu, WP; Maes, BD; Rutgeerts, P; Vanrenterghem, Y; Verbeke, K	1
Ravenstijn, P; Sensenhauser, C; Snoeys, J; Templeton, I	1
Cahn, AP; Georgiou, A; Harrell, AW; Hessel, EM; Marotti, M; Patel, A; Riddell, K; Taskar, KS; Taylor, M; Tracey, H; Wilson, R	1
Li, Z; Reinhart, JM; Tonero, ME	1

Reviews

2 review(s) available for erythromycin and itraconazole

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Current scenario of tetrazole hybrids for antibacterial activity. European journal of medicinal chemistry, 2019, Dec-15, Volume: 184 Topics: Anti-Bacterial Agents; Bacteria; Dose-Response Relationship, Drug; Microbial Sensitivity Tests; Molecular Structure; Structure-Activity Relationship; Tetrazoles	2019

Trials

5 trial(s) available for erythromycin and itraconazole

Article	Year
Plasma buspirone concentrations are greatly increased by erythromycin and itraconazole. Clinical pharmacology and therapeutics, 1997, Volume: 62, Issue:3 Topics: Administration, Oral; Adolescent; Adult; Analysis of Variance; Antifungal Agents; Area Under Curve; Buspirone; Cross-Over Studies; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Double-Blind Method; Drug Interactions; Erythromycin; Female; Humans; Itraconazole; Mixed Function Oxygenases; Protein Synthesis Inhibitors; Psychomotor Performance; Serotonin Receptor Agonists	1997
Effect of erythromycin and itraconazole on the pharmacokinetics of intravenous lignocaine. European journal of clinical pharmacology, 1998, Volume: 54, Issue:7 Topics: Adult; Anti-Bacterial Agents; Cross-Over Studies; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Double-Blind Method; Drug Interactions; Enzyme Inhibitors; Erythromycin; Female; Humans; Injections, Intravenous; Itraconazole; Lidocaine; Male; Mixed Function Oxygenases	1998
Effect of erythromycin and itraconazole on the pharmacokinetics of oral lignocaine. Pharmacology & toxicology, 1999, Volume: 84, Issue:3 Topics: Administration, Oral; Adult; Anesthetics, Local; Cross-Over Studies; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Double-Blind Method; Drug Interactions; Erythromycin; Female; Humans; Itraconazole; Lidocaine; Male; Mixed Function Oxygenases; Placebos; Protein Synthesis Inhibitors	1999
A physiologically based pharmacokinetic modeling approach to predict drug-drug interactions between domperidone and inhibitors of CYP3A4. Biopharmaceutics & drug disposition, 2016, Volume: 37, Issue:1 Topics: Adolescent; Adult; Caco-2 Cells; Computer Simulation; Cytochrome P-450 CYP3A Inhibitors; Domperidone; Dopamine Antagonists; Drug Interactions; Erythromycin; Female; Humans; Itraconazole; Ketoconazole; Male; Microsomes, Liver; Middle Aged; Models, Biological; Young Adult	2016
Drug Interactions for Low-Dose Inhaled Nemiralisib: A Case Study Integrating Modeling, In Vitro, and Clinical Investigations. Drug metabolism and disposition: the biological fate of chemicals, 2020, Volume: 48, Issue:4 Topics: Administration, Inhalation; Adolescent; Adult; Aged; Area Under Curve; Clarithromycin; Computer Simulation; Cross-Over Studies; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Drug Interactions; Erythromycin; Healthy Volunteers; Humans; Indazoles; Indoles; Itraconazole; Male; Microsomes, Liver; Midazolam; Middle Aged; Models, Biological; Oxazoles; Phosphoinositide-3 Kinase Inhibitors; Piperazines; Prospective Studies; Retrospective Studies; Young Adult	2020

Other Studies

18 other study(ies) available for erythromycin and itraconazole

Article	Year
Rational use of in vitro P-glycoprotein assays in drug discovery. The Journal of pharmacology and experimental therapeutics, 2001, Volume: 299, Issue:2 Topics: Adenosine Triphosphatases; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cells, Cultured; Chromatography, Liquid; Enzyme Inhibitors; Fluoresceins; Fluorescent Dyes; Humans; Mass Spectrometry; Pharmacology; Spodoptera	2001
Comparison of in vitro P-glycoprotein screening assays: recommendations for their use in drug discovery. Journal of medicinal chemistry, 2003, Apr-24, Volume: 46, Issue:9 Topics: Adenosine Triphosphatases; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Cells, Cultured; Drug Evaluation, Preclinical; Fluoresceins; Fluorescent Dyes; Humans; Indicators and Reagents; Mice; Models, Molecular; Rhodamines; Species Specificity; Swine	2003
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Three-dimensional quantitative structure-activity relationship analysis of human CYP51 inhibitors. Drug metabolism and disposition: the biological fate of chemicals, 2007, Volume: 35, Issue:3 Topics: Amides; Cytochrome P-450 Enzyme Inhibitors; Enzyme Inhibitors; Humans; Indoles; Models, Molecular; Oxidoreductases; Quantitative Structure-Activity Relationship; Sterol 14-Demethylase	2007
Hologram QSAR model for the prediction of human oral bioavailability. Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24 Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions. Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10 Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection	2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Use of terfenadine and contraindicated drugs. JAMA, 1996, May-01, Volume: 275, Issue:17 Topics: Anti-Bacterial Agents; Antifungal Agents; Clarithromycin; Contraindications; Drug Interactions; Drug Utilization; Erythromycin; Histamine H1 Antagonists; Humans; Itraconazole; Ketoconazole; Pharmaceutical Services; Product Labeling; Retrospective Studies; Terfenadine; Troleandomycin	1996
Buspirone plasma concentrations. Clinical pharmacology and therapeutics, 1998, Volume: 64, Issue:3 Topics: Anti-Anxiety Agents; Anti-Bacterial Agents; Antifungal Agents; Biological Availability; Buspirone; Erythromycin; Humans; Itraconazole; Research Design; Serotonin Receptor Agonists	1998
Drug interactions. The Medical letter on drugs and therapeutics, 1999, Jul-02, Volume: 41, Issue:1056 Topics: Anti-Bacterial Agents; Antifungal Agents; Binding, Competitive; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Erythromycin; Humans; Isoenzymes; Itraconazole; Ketoconazole; Microsomes, Liver; Mixed Function Oxygenases; Pharmacokinetics	1999
Effect of diclofenac, disulfiram, itraconazole, grapefruit juice and erythromycin on the pharmacokinetics of quinidine. British journal of clinical pharmacology, 1999, Volume: 48, Issue:6 Topics: Adult; Aryl Hydrocarbon Hydroxylases; Beverages; Citrus; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP2E1 Inhibitors; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Diclofenac; Disulfiram; Drug Interactions; Enzyme Inhibitors; Erythromycin; Humans; Itraconazole; Male; Mixed Function Oxygenases; Oxidation-Reduction; Quinidine; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases	1999
Prediction of midazolam-CYP3A inhibitors interaction in the human liver from in vivo/in vitro absorption, distribution, and metabolism data. Drug metabolism and disposition: the biological fate of chemicals, 2001, Volume: 29, Issue:4 Pt 1 Topics: Anesthetics, Intravenous; Animals; Aryl Hydrocarbon Hydroxylases; Cimetidine; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Inhibitors; Erythromycin; Humans; Intestinal Absorption; Itraconazole; Kinetics; Liver; Male; Microsomes, Liver; Midazolam; Models, Biological; Oxidoreductases, N-Demethylating; Portal Vein; Protein Binding; Rats; Rats, Sprague-Dawley; Tissue Distribution	2001
Measurement of hepatic and intestinal CYP3A4 and PGP activity by combined po + iv [14C]erythromycin breath and urine test. American journal of physiology. Gastrointestinal and liver physiology, 2003, Volume: 285, Issue:3 Topics: Administration, Oral; ATP Binding Cassette Transporter, Subfamily B, Member 1; Breath Tests; Carbon Radioisotopes; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Erythromycin; Feces; Female; Gastric Acid; Gastric Emptying; Humans; Injections, Intravenous; Intestinal Mucosa; Itraconazole; Kidney Transplantation; Liver; Male; Postoperative Period; Reference Values	2003
Cytochrome P450 reaction phenotyping of itraconazole hydroxylation in the dog. Journal of veterinary pharmacology and therapeutics, 2022, Volume: 45, Issue:3 Topics: Animals; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dogs; Enzyme Inhibitors; Erythromycin; Hydroxylation; Itraconazole; Microsomes, Liver; Quinidine	2022