Page last updated: 2024-08-21

erythromycin and hmr 3647

erythromycin has been researched along with hmr 3647 in 49 studies

Research

Studies (49)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	33 (67.35)	29.6817
2010's	15 (30.61)	24.3611
2020's	1 (2.04)	2.80

Authors

Authors	Studies
Alder, J; Chu, DT; Clark, RF; Ewing, P; Flamm, RK; Ma, Z; Mitten, M; Nilius, AM; Or, YS; Wang, S	1
Alder, J; Brazzale, A; Cao, Z; Chu, DT; Clark, RF; Ewing, P; Flamm, R; Griesgraber, G; Li, L; Ma, Z; Meulbroek, J; Mitten, M; Nemoto, PA; Nilius, AM; Or, YS; Phan, LT; Plattner, JJ; Rupp, MJ; Shortridge, VD; Wang, S; Yong, H; Zhang, S; Zhang, X; Zhong, P	1
Carter, JJ; Daly, MM; Englund, EE; Keyes, RF; Ma, Z; Nilius, AM; Stone, GG	1
Beebe, X; Bui, MH; Djuric, SW; Ma, Z; Mitten, MJ; Nilius, AM; Yang, F	1
Akritopoulou-Zanze, I; Daly, MM; Djuric, SW; Hensey, DM; Ma, Z; Marron, TG; Nilius, AM; Phelan, KM; Stone, GG; Yong, H	1
Abbanat, D; Baum, EZ; Bush, K; Foleno, BD; Henninger, TC; Hilliard, JJ; Hlasta, DJ; Macielag, MJ; Xu, X	1
Abbanat, D; Bush, K; Foleno, B; Henninger, T; Hilliard, J; Macielag, M; Xu, X	1
Abbanat, D; Bush, K; Foleno, BD; Henninger, TC; Macielag, MJ; Marinelli, BA; Zhu, B	1
Fu, H; Gu, X; Katz, L; Marquez, S; Myles, DC	1
Abbanat, D; Bush, K; Foleno, BD; Grant, EB; Guiadeen, D; Macielag, MJ	1
Abbanat, D; Bush, K; Foleno, BD; Henninger, TC; Hilliard, JJ; Macielag, MJ; Tennakoon, MA	1
Klugman, KP; Low, DE; Smith, AM; Wolter, N	1
Fiett, J; Gniadkowski, M; Grzesiowski, P; Hryniewicz, W; Izdebski, R; Sadowy, E	1
Abbanat, D; Bush, K; Foleno, BD; Macielag, MJ; Marinelli, BA; Zhu, B	1
Ardanuy, C; Bouza, E; Calatayud, L; Cercenado, E; Fenoll, A; Liñares, J; Martín, R; Pallares, R	1
Jansen, WT; Milatovic, D; Verel, A; Verhoef, J	1
Beceiro, A; Bou, G; Canle, D; Fernández, A; Lasa, I; Latasa, C; Mallo, S; Molina, F; Pérez, A; Pérez, S; Poza, M; Tomás, Mdel M; Villanueva, R	1
Andricopulo, AD; Moda, TL; Montanari, CA	1
Calvet, L; Devine, R; Dubreuil, L; Jean-Pierre, H; Jumas-Bilak, E; Marchandin, H; Mercier, G; Morio, F	1
Chiba, N; Hasegawa, K; Iwata, S; Matsubara, K; Morozumi, M; Nakayama, E; Sunakawa, K; Takayanagi, R; Ubukata, K	1
Douthwaite, S; Farrell, DJ; Klugman, KP; Northwood, JB; Smith, AM; Wolter, N	1
Bailey, M; Chettiath, T; Mankin, AS	1
Gentry, DR; Holmes, DJ	1
Danese, P; DeVito, J; Franceschi, F; Lawrence, L; Sutcliffe, J	1
Baquero, F; Cantón, R; de la Pedrosa, EG; Galán, JC; Morosini, MI; Reinert, RR; Ruiz-Garbajosa, P; van der Linden, M	1
Lombardo, F; Obach, RS; Waters, NJ	1
Benton, BM; Debabov, DV; Difuntorum, S; Krause, KM; Renelli, M; Wu, TX	1
Chen, Z; Gai, Y; Or, YS; Polemeropoulos, A; Tang, D; Wang, Z; Xu, G	1
Dinos, GP; Kalpaxis, DL; Kouvela, EC; Wilson, DN	1
Brown-Elliott, BA; Nash, KA; Wallace, RJ	1
Jiang, LJ; Or, YS; Wang, M	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Arhin, FF; Draghi, DC; Moeck, G; Parr, TR; Pillar, CM; Sahm, DF	1
Appelbaum, PC; Beachel, L; Clark, C; Dewasse, B; Kosowska-Shick, KM; McGhee, P; Nagai, K	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Hakanen, AJ; Huovinen, P; Kotilainen, P; Lehtopolku, M; Nakari, UM; Siitonen, A	1
Castanheira, M; Jones, RN; Woosley, LN	1
Shakya, T; Wright, GD	1
Gunell, M; Hakanen, AJ; Huovinen, P; Jalava, J; Kotilainen, P; Siitonen, A	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Biedenbach, DJ; Castanheira, M; Jones, RN	1
Ekins, S; Williams, AJ; Xu, JJ	1
Bhateja, P; Chakrabarti, A; Das, B; Dullu, J; Hajare, AK; Jadhav, JS; Kumar, R; Pandya, M; Ramkumar, G; Rathy, S; Surase, YB; Venkataramanan, R	1
Klepacki, D; LeTourneau, N; Mankin, A; Melman, A; Vimal, P	1
Chen, X; Lei, P; Liu, L; Liu, Y; Xu, P; Xu, Y; Zhu, D	1
Atamanyuk, D; Bonvin, Y; Briet, S; Denis, A; Desroy, N; Drocourt, E; Durant, L; Escaich, S; Faivre, F; Floquet, S; Gerusz, V; Junop, MS; Lee, TW; LeFralliec, G; Moreau, F; Oliveira, C; Oxoby, M; Verhey, TB; Vongsouthi, V	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Bertrand, D; Fernandes, P; Pereira, D; Watkins, PB	1

Reviews

1 review(s) available for erythromycin and hmr 3647

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016

Trials

1 trial(s) available for erythromycin and hmr 3647

Article	Year
Pharmacokinetics of EDP-420 after ascending single oral doses in healthy adult volunteers. Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:5 Topics: Administration, Oral; Adolescent; Adult; Anti-Bacterial Agents; Bridged-Ring Compounds; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Humans; Macrolides; Male; Middle Aged; Treatment Outcome; Young Adult	2009

Article

Year

Pharmacokinetics of EDP-420 after ascending single oral doses in healthy adult volunteers.

Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:5

Topics: Administration, Oral; Adolescent; Adult; Anti-Bacterial Agents; Bridged-Ring Compounds; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Humans; Macrolides; Male; Middle Aged; Treatment Outcome; Young Adult

2009

Other Studies

47 other study(ies) available for erythromycin and hmr 3647

Article	Year
Design, synthesis, and antimicrobial activity of 6-O-substituted ketolides active against resistant respiratory tract pathogens. Journal of medicinal chemistry, 2000, Mar-23, Volume: 43, Issue:6 Topics: Animals; Anti-Bacterial Agents; Drug Design; Drug Resistance, Microbial; Haemophilus influenzae; Lung; Lung Diseases; Macrolides; Mice; Models, Molecular; Rats; Respiratory Tract Infections; Staphylococcal Infections; Staphylococcus; Streptococcal Infections; Streptococcus; Structure-Activity Relationship	2000
Novel erythromycin derivatives with aryl groups tethered to the C-6 position are potent protein synthesis inhibitors and active against multidrug-resistant respiratory pathogens. Journal of medicinal chemistry, 2001, Nov-22, Volume: 44, Issue:24 Topics: Animals; Anti-Bacterial Agents; Carbamates; Cell-Free System; Drug Resistance, Multiple; Erythromycin; Haemophilus influenzae; Ketolides; Lung; Mice; Models, Molecular; Protein Biosynthesis; Protein Synthesis Inhibitors; Rats; Respiratory Tract Infections; Ribosomes; Staphylococcus aureus; Streptococcus pneumoniae; Streptococcus pyogenes; Structure-Activity Relationship; Transcription, Genetic	2001
Synthesis and antibacterial activity of 6-O-arylbutynyl ketolides with improved activity against some key erythromycin-resistant pathogens. Journal of medicinal chemistry, 2003, May-08, Volume: 46, Issue:10 Topics: Alkynes; Anti-Bacterial Agents; Drug Resistance, Bacterial; Erythromycin; Haemophilus influenzae; Microbial Sensitivity Tests; Staphylococcus; Structure-Activity Relationship	2003
Synthesis and antibacterial activity of 6-O-arylpropargyl-9-oxime-11,12-carbamate ketolides. Bioorganic & medicinal chemistry letters, 2004, May-17, Volume: 14, Issue:10 Topics: Animals; Anti-Bacterial Agents; Disease Models, Animal; Drug Resistance, Bacterial; Haemophilus influenzae; Ketolides; Macrolides; Rats; Respiratory Tract Infections; Staphylococcus; Structure-Activity Relationship	2004
Synthesis and antibacterial activity of novel bifunctional macrolides. Bioorganic & medicinal chemistry letters, 2004, Jul-16, Volume: 14, Issue:14 Topics: Anti-Bacterial Agents; Bacteria; Cell Membrane; Drug Resistance; Drug Resistance, Bacterial; Erythromycin; Macrolides; Microbial Sensitivity Tests; Structure-Activity Relationship	2004
Synthesis and antibacterial activity of C-6 carbamate ketolides, a novel series of orally active ketolide antibiotics. Bioorganic & medicinal chemistry letters, 2004, Sep-06, Volume: 14, Issue:17 Topics: Administration, Oral; Animals; Anti-Bacterial Agents; Carbamates; Female; Ketolides; Mice; Microbial Sensitivity Tests	2004
Synthesis and antibacterial activity of C2-fluoro, C6-carbamate ketolides, and their C9-oximes. Bioorganic & medicinal chemistry letters, 2005, Feb-15, Volume: 15, Issue:4 Topics: Anti-Bacterial Agents; Ketolides; Microbial Sensitivity Tests; Oximes; Streptococcus; Structure-Activity Relationship	2005
Synthesis and antibacterial activity of 3-O-acyl-6-O-carbamoyl erythromycin A derivatives. Bioorganic & medicinal chemistry letters, 2006, Feb-15, Volume: 16, Issue:4 Topics: Anti-Bacterial Agents; Bacteria; Erythromycin; Ketolides; Microbial Sensitivity Tests; Molecular Conformation; Stereoisomerism; Structure-Activity Relationship	2006
Synthesis and in vitro antibiotic activity of 16-membered 9-O-arylalkyloxime macrolides. Bioorganic & medicinal chemistry letters, 2006, Mar-01, Volume: 16, Issue:5 Topics: Alkylation; Anti-Bacterial Agents; Gram-Negative Bacteria; Gram-Positive Bacteria; Macrolides; Methylation; Molecular Structure; Oximes; Ribosomes; Structure-Activity Relationship	2006
Synthesis and antibacterial activity of 6-O-heteroarylcarbamoyl-11,12-lactoketolides. Bioorganic & medicinal chemistry letters, 2006, Apr-01, Volume: 16, Issue:7 Topics: Anti-Bacterial Agents; Haemophilus influenzae; Ketolides; Magnetic Resonance Spectroscopy; Microbial Sensitivity Tests; Streptococcus pneumoniae; Structure-Activity Relationship	2006
Synthesis and antibacterial activity of C6-carbazate ketolides. Bioorganic & medicinal chemistry letters, 2006, Dec-15, Volume: 16, Issue:24 Topics: Anti-Bacterial Agents; Hydrazines; Ketolides; Microbial Sensitivity Tests; Staphylococcus; Structure-Activity Relationship	2006
High-level telithromycin resistance in a clinical isolate of Streptococcus pneumoniae. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:3 Topics: Anti-Bacterial Agents; Bacterial Proteins; Culture Media; Drug Resistance, Bacterial; Genotype; Humans; Ketolides; Methyltransferases; Microbial Sensitivity Tests; Mutation; Phenotype; Pneumococcal Infections; Ribosomal Proteins; Streptococcus pneumoniae	2007
Clonal diversity and resistance mechanisms in tetracycline-nonsusceptible Streptococcus pneumoniae isolates in Poland. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:4 Topics: Bacterial Proteins; Cell Lineage; DNA Transposable Elements; Genetic Variation; Poland; Streptococcus pneumoniae; Tetracycline; Tetracycline Resistance	2007
Synthesis and antibacterial activity of 3-keto-6-O-carbamoyl-11,12-cyclic thiocarbamate erythromycin A derivatives. Bioorganic & medicinal chemistry letters, 2007, Jul-15, Volume: 17, Issue:14 Topics: Anti-Bacterial Agents; Erythromycin; Microbial Sensitivity Tests; Staphylococcus aureus; Streptococcus pneumoniae	2007
Serotypes, Clones, and Mechanisms of Resistance of Erythromycin-Resistant Streptococcus pneumoniae Isolates Collected in Spain. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:9 Topics: Anti-Bacterial Agents; Clone Cells; Drug Resistance, Multiple, Bacterial; Electrophoresis, Polyacrylamide Gel; Erythromycin; Genes, Bacterial; Microbial Sensitivity Tests; Phenotype; Pneumococcal Infections; Serotyping; Spain; Streptococcus pneumoniae; Tetracycline Resistance	2007
In vitro activity of telavancin against gram-positive clinical isolates recently obtained in Europe. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:9 Topics: Aminoglycosides; Anti-Bacterial Agents; Drug Resistance, Multiple, Bacterial; Europe; Gram-Positive Bacteria; Gram-Positive Bacterial Infections; Humans; Lipoglycopeptides; Methicillin Resistance; Microbial Sensitivity Tests; Staphylococcus aureus; Streptococcus agalactiae; Streptococcus pyogenes; Vancomycin Resistance; Viridans Streptococci	2007
Cloning, nucleotide sequencing, and analysis of the AcrAB-TolC efflux pump of Enterobacter cloacae and determination of its involvement in antibiotic resistance in a clinical isolate. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:9 Topics: Bacterial Proteins; Base Sequence; beta-Lactamases; Carrier Proteins; Cloning, Molecular; DNA, Bacterial; Drug Resistance, Bacterial; Enterobacter cloacae; Enterobacteriaceae Infections; Genes, MDR; Genetic Vectors; Humans; Microbial Sensitivity Tests; Molecular Sequence Data; Plasmids; Porins	2007
Hologram QSAR model for the prediction of human oral bioavailability. Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24 Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2007
Antimicrobial susceptibilities and clinical sources of Dialister species. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:12 Topics: Anti-Bacterial Agents; Drug Resistance, Bacterial; Gram-Negative Bacterial Infections; Humans; Microbial Sensitivity Tests; Species Specificity; Veillonellaceae	2007
Increased macrolide resistance of Mycoplasma pneumoniae in pediatric patients with community-acquired pneumonia. Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:1 Topics: Adolescent; Anti-Bacterial Agents; Child; Child, Preschool; Community-Acquired Infections; Drug Resistance, Bacterial; Humans; Infant; Infant, Newborn; Macrolides; Microbial Sensitivity Tests; Mycoplasma pneumoniae; Pneumonia, Mycoplasma; RNA, Ribosomal, 23S	2008
Telithromycin resistance in Streptococcus pneumoniae is conferred by a deletion in the leader sequence of erm(B) that increases rRNA methylation. Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:2 Topics: 5' Untranslated Regions; Amino Acid Sequence; Anti-Bacterial Agents; Drug Resistance, Bacterial; Humans; Ketolides; Methylation; Methyltransferases; Microbial Sensitivity Tests; Molecular Sequence Data; RNA, Ribosomal; Sequence Deletion; Streptococcus pneumoniae	2008
Induction of erm(C) expression by noninducing antibiotics. Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:3 Topics: Amino Acid Sequence; Anti-Bacterial Agents; Drug Resistance, Bacterial; Enzyme Induction; Escherichia coli; Gene Expression Regulation, Bacterial; Ketolides; Macrolides; Methyltransferases; Microbial Sensitivity Tests; Molecular Sequence Data; Protein Conformation; Protein Sorting Signals; Ribosomes; RNA, Messenger	2008
Selection for high-level telithromycin resistance in Staphylococcus aureus yields mutants resulting from an rplB-to-rplV gene conversion-like event. Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:3 Topics: Amino Acid Sequence; Anti-Bacterial Agents; Base Sequence; Drug Resistance, Bacterial; Gene Conversion; Ketolides; Microbial Sensitivity Tests; Molecular Sequence Data; Mutation; Ribosomal Proteins; Staphylococcus aureus	2008
In vitro activities of the Rx-01 oxazolidinones against hospital and community pathogens. Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:5 Topics: Anti-Infective Agents; Bacteria; Community-Acquired Infections; Cross Infection; Enterococcus; Humans; Methicillin Resistance; Microbial Sensitivity Tests; Molecular Structure; Oxazolidinones; Respiratory System; Staphylococcus; Staphylococcus aureus; Streptococcus; Streptococcus pneumoniae	2008
Polyclonal population structure of Streptococcus pneumoniae isolates in Spain carrying mef and mef plus erm(B). Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:6 Topics: Anti-Bacterial Agents; Bacterial Proteins; Drug Resistance, Bacterial; Electrophoresis, Gel, Pulsed-Field; Erythromycin; Humans; Membrane Proteins; Methyltransferases; Microbial Sensitivity Tests; Sequence Analysis, DNA; Serotyping; Spain; Streptococcus pneumoniae	2008
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
In vitro activity of telavancin against resistant gram-positive bacteria. Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:7 Topics: Aminoglycosides; Anti-Bacterial Agents; Drug Resistance, Bacterial; Enterococcus; Gram-Positive Bacteria; Gram-Positive Bacterial Infections; Humans; In Vitro Techniques; Lipoglycopeptides; Methicillin Resistance; Microbial Sensitivity Tests; Staphylococcus; Streptococcus	2008
Synthesis of 3,6-bicyclolides: a novel class of macrolide antibiotics. Bioorganic & medicinal chemistry letters, 2008, Dec-15, Volume: 18, Issue:24 Topics: Animals; Anti-Bacterial Agents; Chemistry, Pharmaceutical; Crystallography, X-Ray; Drug Design; Drug Resistance, Multiple; Humans; Macrolides; Mice; Microbial Sensitivity Tests; Models, Chemical; Molecular Conformation; Respiratory System	2008
Distinct mode of interaction of a novel ketolide antibiotic that displays enhanced antimicrobial activity. Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:4 Topics: Anti-Bacterial Agents; Erythromycin; Escherichia coli; Ketolides; RNA, Ribosomal, 23S; Structure-Activity Relationship	2009
A novel gene, erm(41), confers inducible macrolide resistance to clinical isolates of Mycobacterium abscessus but is absent from Mycobacterium chelonae. Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:4 Topics: Amino Acid Sequence; Clarithromycin; Drug Resistance, Bacterial; Humans; Macrolides; Methyltransferases; Microbial Sensitivity Tests; Molecular Sequence Data; Mycobacterium chelonae; Nontuberculous Mycobacteria; Polymerase Chain Reaction; RNA	2009
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:11 Topics: Anti-Bacterial Agents; Drug Resistance, Bacterial; Enterococcus faecium; Glycopeptides; Gram-Positive Bacteria; Humans; Lipoglycopeptides; Microbial Sensitivity Tests; Staphylococcus aureus; Streptococcus	2009
In vitro activity of CEM-101 against Streptococcus pneumoniae and Streptococcus pyogenes with defined macrolide resistance mechanisms. Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:1 Topics: Anti-Bacterial Agents; Drug Resistance, Bacterial; Macrolides; Microbial Sensitivity Tests; Penicillin G; Streptococcus pneumoniae; Streptococcus pyogenes; Triazoles	2010
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Antimicrobial susceptibilities of multidrug-resistant Campylobacter jejuni and C. coli strains: in vitro activities of 20 antimicrobial agents. Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:3 Topics: Anti-Bacterial Agents; Campylobacter coli; Campylobacter Infections; Campylobacter jejuni; Carbapenems; Drug Resistance, Multiple, Bacterial; Erythromycin; Feces; Finland; Humans; Macrolides; Microbial Sensitivity Tests; Minocycline; Tigecycline	2010
CEM-101 activity against Gram-positive organisms. Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:5 Topics: Anti-Bacterial Agents; Azithromycin; Ceftriaxone; Clarithromycin; Drug Resistance, Bacterial; Drug Synergism; Erythromycin; Gentamicins; Gram-Positive Bacteria; Ketolides; Macrolides; Microbial Sensitivity Tests; Ofloxacin; Staphylococcus aureus; Staphylococcus epidermidis; Streptococcus pneumoniae; Streptococcus pyogenes; Triazoles; Trimethoprim, Sulfamethoxazole Drug Combination; Vancomycin	2010
Nucleotide selectivity of antibiotic kinases. Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:5 Topics: Anti-Bacterial Agents; Bacteria; Binding, Competitive; Drug Resistance, Bacterial; Guanosine Triphosphate; Kanamycin Kinase; Models, Chemical; Nucleotides; Phosphotransferases (Alcohol Group Acceptor); Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Substrate Specificity	2010
In vitro activity of azithromycin against nontyphoidal Salmonella enterica. Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:8 Topics: Anti-Bacterial Agents; Anti-Infective Agents; Azithromycin; Drug Resistance, Bacterial; Finland; Fluoroquinolones; Humans; Microbial Sensitivity Tests; Salmonella enterica; Salmonella Infections	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
Determination of CEM-101 activity tested against clinical isolates of Neisseria meningitidis from a worldwide collection. Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:9 Topics: Anti-Bacterial Agents; Azithromycin; Ceftriaxone; Ciprofloxacin; Humans; Ketolides; Macrolides; Microbial Sensitivity Tests; Minocycline; Neisseria meningitidis; Penicillins; Rifampin; Sulfamethoxazole; Triazoles; Trimethoprim	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
Synthesis and antibacterial activity of a novel series of acylides active against community acquired respiratory pathogens. Bioorganic & medicinal chemistry letters, 2012, Jan-01, Volume: 22, Issue:1 Topics: Anti-Bacterial Agents; Chemistry, Pharmaceutical; Clarithromycin; Drug Design; Drug Resistance, Bacterial; Haemophilus influenzae; Humans; Ketolides; Microbial Sensitivity Tests; Models, Chemical; Nitrogen; Respiratory Tract Infections; Streptococcus pneumoniae	2012
Synthesis and antibacterial activity of desosamine-modified macrolide derivatives. Bioorganic & medicinal chemistry letters, 2012, Jul-15, Volume: 22, Issue:14 Topics: Amino Sugars; Anti-Bacterial Agents; Escherichia coli; Macrolides; Microbial Viability; Models, Molecular; Molecular Structure; Staphylococcus aureus; Structure-Activity Relationship	2012
Synthesis and antibacterial activity of novel modified 5-O-desosamine ketolides. Bioorganic & medicinal chemistry letters, 2012, Dec-15, Volume: 22, Issue:24 Topics: Anti-Bacterial Agents; Dose-Response Relationship, Drug; Ketolides; Microbial Sensitivity Tests; Molecular Conformation; Staphylococcus aureus; Staphylococcus epidermidis; Streptococcus Phages; Streptococcus pneumoniae; Structure-Activity Relationship	2012
Novel HldE-K inhibitors leading to attenuated Gram negative bacterial virulence. Journal of medicinal chemistry, 2013, Feb-28, Volume: 56, Issue:4 Topics: Anti-Bacterial Agents; Benzothiazoles; Escherichia coli; Lipopolysaccharides; Microbial Sensitivity Tests; Multienzyme Complexes; Nucleotidyltransferases; Phosphotransferases (Alcohol Group Acceptor); Structure-Activity Relationship; Triazines; Virulence	2013
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Differentiating the Pharmacodynamics and Toxicology of Macrolide and Ketolide Antibiotics. Journal of medicinal chemistry, 2020, 06-25, Volume: 63, Issue:12 Topics: Animals; Anti-Bacterial Agents; Bacteria; Bacterial Infections; Drug Resistance, Bacterial; Drug-Related Side Effects and Adverse Reactions; Humans; Ketolides; Macrolides	2020