Page last updated: 2024-08-21

erythromycin and fluconazole

erythromycin has been researched along with fluconazole in 39 studies

Research

Studies (39)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (7.69)18.2507
2000's14 (35.90)29.6817
2010's21 (53.85)24.3611
2020's1 (2.56)2.80

Authors

AuthorsStudies
Dantzig, AH; Ekins, S; Kim, RB; Lan, LB; Leake, BF; Schuetz, EG; Schuetz, JD; Shepard, RL; Wikel, JH; Winter, MA; Wrighton, SA; Yasuda, K1
Furuya, K; Lan, LB; Sanglard, D; Schuetz, EG; Schuetz, JD; Yasuda, K1
Johans, C; Kinnunen, PK; Söderlund, T; Suomalainen, P1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Ekins, S; Harwood, HJ; Hoover, DJ; Lawton, MP; Mankowski, DC; Treadway, JL1
Lombardo, F; Obach, RS; Waters, NJ1
Bavikar, SN; Chattopadhyay, S; Deshpande, MV; Dodd, RH; Hazra, BG; Kadreppa, S; Pore, VS; Salunke, DB; Shirazi, F; Thierry, J1
Pratim Roy, P; Roy, K1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Chen, X; Lin, X; Skolnik, S; Wang, J1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Deshpande, MV; Hazra, BG; Pore, VS; Salunke, DB; Shingate, BB; Shirazi, F1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Beaumont, K; Di, L; Maurer, TS; Smith, DA1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Chen, F; Chen, W; Lan, L; Li, B; Li, J; Liu, Y; Mao, F; Ni, S; Wei, H; Zhu, J1
Blanchet, M; Bourguet-Kondracki, ML; Brunel, JM; Cadelis, MM; Copp, BR; Li, SA; Sue, K; Vidal, N1
Gao, F; Huang, G; Wang, T; Xiao, J1
Blanchet, M; Bourguet-Kondracki, ML; Brunel, JM; Cadelis, MM; Copp, BR; Kang, W; Pike, EIW; Vidal, N; Wu, Z1
Gao, F; Huang, G; Xiao, J1
Bourguet-Kondracki, ML; Cadelis, MM; Copp, BR; Deed, RC; Douafer, H; Li, SA; Michel Brunel, J1
Ariyaratnam, S; Pemberton, M; Sloan, P; Thakker, NS; Thornhill, MH1
Alpert, NM; Babich, JW; Fischman, AJ; Rubin, RH1
Kawamura, T; Kawanami, R; Mochizuki, Y; Nakahara, Y1
Hattori, A; Iida, T; Nishiyama, C1
Bhoopathy, S; Karnes, HT; Sarkar, MA1
Beckmann, BM; Hinterseer, M; Irlbeck, M; Kaab, S; Ney, L; Pfeufer, A; Steinbeck, G1
Blough, DK; Dees, EC; Givens, RC; Hawke, RL; Isoherranen, N; Iwanaga, K; Lamba, JK; Ludington, SR; Paine, MF; Pusek, SN; Schuetz, EG; Thummel, KE; Watkins, PB1
Boulenc, X; Hachad, H; Levy, RH; Ragueneau-Majlessi, I; Rauch, C1
Fraczkiewicz, G; Shi, JG; Williams, WV; Yeleswaram, S1
Basmadjian, C; Jakkidi, M; Roy, S1
Li, A; Rong, H; Welty, D; Yeo, K1

Reviews

5 review(s) available for erythromycin and fluconazole

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Antibacterial activity study of 1,2,4-triazole derivatives.
    European journal of medicinal chemistry, 2019, Jul-01, Volume: 173

    Topics: Anti-Bacterial Agents; Bacteria; Dose-Response Relationship, Drug; Microbial Sensitivity Tests; Molecular Structure; Structure-Activity Relationship; Triazoles

2019
Current scenario of tetrazole hybrids for antibacterial activity.
    European journal of medicinal chemistry, 2019, Dec-15, Volume: 184

    Topics: Anti-Bacterial Agents; Bacteria; Dose-Response Relationship, Drug; Microbial Sensitivity Tests; Molecular Structure; Structure-Activity Relationship; Tetrazoles

2019
The role of positron emission tomography in pharmacokinetic analysis.
    Drug metabolism reviews, 1997, Volume: 29, Issue:4

    Topics: Animals; Anti-Infective Agents; Biological Availability; Brain; Central Nervous System Agents; Drug Monitoring; Erythromycin; Fluconazole; Fluoroquinolones; Humans; Rabbits; Radiochemistry; Radiopharmaceuticals; Tissue Distribution; Tomography, Emission-Computed

1997
[A case of Folliculitis barbae Candidomycetica].
    Nihon Ishinkin Gakkai zasshi = Japanese journal of medical mycology, 2001, Volume: 42, Issue:2

    Topics: Administration, Oral; Aged; Anti-Inflammatory Agents; Candidiasis, Cutaneous; Diagnosis, Differential; Erythromycin; Facial Dermatoses; Fluconazole; Folliculitis; Humans; Male; Onychomycosis; Steroids; Treatment Outcome

2001

Other Studies

34 other study(ies) available for erythromycin and fluconazole

ArticleYear
Three-dimensional quantitative structure-activity relationships of inhibitors of P-glycoprotein.
    Molecular pharmacology, 2002, Volume: 61, Issue:5

    Topics: Animals; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Caco-2 Cells; Ergonovine; Fluoxetine; Humans; Models, Molecular; Oxytocics; Protein Conformation; Selective Serotonin Reuptake Inhibitors; Structure-Activity Relationship; Swine; Transfection; Vinblastine

2002
Interaction of cytochrome P450 3A inhibitors with P-glycoprotein.
    The Journal of pharmacology and experimental therapeutics, 2002, Volume: 303, Issue:1

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Cell Line; Cells, Cultured; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dihydroergocryptine; Drug Interactions; Enzyme Inhibitors; Fluconazole; Humans; Mice; Mice, Knockout; Microsomes, Liver; Oxidoreductases, N-Demethylating; Recombinant Proteins; Reserpine; Swine; Tissue Distribution; Transfection; Vinblastine

2002
Surface activity profiling of drugs applied to the prediction of blood-brain barrier permeability.
    Journal of medicinal chemistry, 2004, Mar-25, Volume: 47, Issue:7

    Topics: Blood-Brain Barrier; Lipid Bilayers; Micelles; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship; Surface Properties

2004
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Three-dimensional quantitative structure-activity relationship analysis of human CYP51 inhibitors.
    Drug metabolism and disposition: the biological fate of chemicals, 2007, Volume: 35, Issue:3

    Topics: Amides; Cytochrome P-450 Enzyme Inhibitors; Enzyme Inhibitors; Humans; Indoles; Models, Molecular; Oxidoreductases; Quantitative Structure-Activity Relationship; Sterol 14-Demethylase

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Synthesis of chimeric tetrapeptide-linked cholic acid derivatives: impending synergistic agents.
    Bioorganic & medicinal chemistry letters, 2008, Oct-15, Volume: 18, Issue:20

    Topics: Anti-Bacterial Agents; beta-Alanine; Cell Line; Cell Line, Tumor; Chemistry, Pharmaceutical; Cholic Acid; Drug Design; Erythromycin; Fluconazole; Glycine; Humans; Models, Chemical; Molecular Conformation; Peptides; Polymyxin B

2008
Comparative chemometric modeling of cytochrome 3A4 inhibitory activity of structurally diverse compounds using stepwise MLR, FA-MLR, PLS, GFA, G/PLS and ANN techniques.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:7

    Topics: Algorithms; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Enzyme Inhibitors; Factor Analysis, Statistical; Least-Squares Analysis; Linear Models; Models, Molecular; Neural Networks, Computer; Quantitative Structure-Activity Relationship; Reproducibility of Results

2009
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Attenuation of intestinal absorption by major efflux transporters: quantitative tools and strategies using a Caco-2 model.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:2

    Topics: Adenosine; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Sub-Family B Member 4; ATP-Binding Cassette Transporters; Biological Transport; Caco-2 Cells; Chromatography, Liquid; Dibenzocycloheptenes; Diketopiperazines; Drug Discovery; Heterocyclic Compounds, 4 or More Rings; Humans; Intestinal Absorption; Mass Spectrometry; Models, Biological; Neoplasm Proteins; Pharmaceutical Preparations; Predictive Value of Tests; Propionates; Quinolines; Substrate Specificity

2011
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Stereoselective synthesis and antimicrobial activity of steroidal C-20 tertiary alcohols with thiazole/pyridine side chain.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:9

    Topics: Alcohols; Anti-Infective Agents; Bacteria; Chromatography, Liquid; Fungi; Magnetic Resonance Spectroscopy; Mass Spectrometry; Microbial Sensitivity Tests; Pyridines; Stereoisomerism; Thiazoles

2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Volume of Distribution in Drug Design.
    Journal of medicinal chemistry, 2015, Aug-13, Volume: 58, Issue:15

    Topics: Drug Design; Half-Life; Pharmacokinetics

2015
Novel Terminal Bipheny-Based Diapophytoene Desaturases (CrtN) Inhibitors as Anti-MRSA/VISR/LRSA Agents with Reduced hERG Activity.
    Journal of medicinal chemistry, 2018, 01-11, Volume: 61, Issue:1

    Topics: Animals; Drug Design; Enzyme Inhibitors; ERG1 Potassium Channel; HEK293 Cells; Hep G2 Cells; Humans; Inhibitory Concentration 50; Methicillin-Resistant Staphylococcus aureus; Mice; Oxidoreductases; Rats; Safety; Solubility; Structure-Activity Relationship; Water

2018
6-Bromoindolglyoxylamido derivatives as antimicrobial agents and antibiotic enhancers.
    Bioorganic & medicinal chemistry, 2019, 05-15, Volume: 27, Issue:10

    Topics: Anti-Bacterial Agents; Anti-Infective Agents; Cell Line; Cell Survival; Drug Resistance, Bacterial; Erythrocytes; Fungi; Gram-Negative Bacteria; Gram-Positive Bacteria; Hemolysis; Humans; Indoles; Microbial Sensitivity Tests; Polyamines

2019
Exploration of the antibiotic potentiating activity of indolglyoxylpolyamines.
    European journal of medicinal chemistry, 2019, Dec-01, Volume: 183

    Topics: Anti-Bacterial Agents; Cell Line; Cell Membrane Permeability; Cell Survival; Cephalosporins; Gram-Negative Bacteria; Hemolysis; Humans; Hydrolysis; Indoles; Microbial Sensitivity Tests; Signal Transduction; Spermine

2019
Valorisation of the diterpene podocarpic acid - Antibiotic and antibiotic enhancing activities of polyamine conjugates.
    Bioorganic & medicinal chemistry, 2022, 06-15, Volume: 64

    Topics: Abietanes; Adjuvants, Pharmaceutic; Animals; Anti-Bacterial Agents; Anti-Infective Agents; Escherichia coli; Mammals; Microbial Sensitivity Tests; Polyamines; Structure-Activity Relationship

2022
Treating oral candidiasis: potentially fatal.
    British dental journal, 1997, Aug-09, Volume: 183, Issue:3

    Topics: Anti-Bacterial Agents; Anticoagulants; Antifungal Agents; Candidiasis, Oral; Drug Interactions; Erythromycin; Fluconazole; Humans; Warfarin

1997
[Successful treatment of allergic bronchopulmonary aspergillosis with erythromycin and fluconazole].
    Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society, 1999, Volume: 37, Issue:4

    Topics: Adult; Aspergillosis, Allergic Bronchopulmonary; Drug Therapy, Combination; Erythromycin; Female; Fluconazole; Humans

1999
Characterization of quinidine 3-hydroxylation as a probe for the CYP 3A enzyme using a novel capillary electrophoresis technique.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2002, Volume: 16, Issue:4-5

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; Biomarkers; Cytochrome P-450 CYP3A; Electrophoresis, Capillary; Enzyme Inhibitors; Erythromycin; Fluconazole; Hydroxylation; Ketoconazole; Microsomes, Liver; Oxidoreductases, N-Demethylating; Quinidine; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Sensitivity and Specificity; Stereoisomerism

2002
Acute respiratory distress syndrome with transiently impaired left ventricular function and Torsades de Pointes arrhythmia unmasking congenital long QT syndrome in a 25-yr-old woman.
    British journal of anaesthesia, 2006, Volume: 97, Issue:2

    Topics: Adult; Anti-Bacterial Agents; Antifungal Agents; Echocardiography; ERG1 Potassium Channel; Erythromycin; Ether-A-Go-Go Potassium Channels; Female; Fluconazole; Humans; Hypokalemia; Long QT Syndrome; Mutation; Recurrence; Respiratory Distress Syndrome; Torsades de Pointes; Treatment Outcome; Ventricular Dysfunction, Left

2006
The influence of CYP3A5 expression on the extent of hepatic CYP3A inhibition is substrate-dependent: an in vitro-in vivo evaluation.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:1

    Topics: Adolescent; Adult; Animals; Baculoviridae; Blotting, Western; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Erythromycin; Female; Fluconazole; Genetic Vectors; Genotype; Humans; In Vitro Techniques; Insecta; Male; Microsomes, Liver; Midazolam; Middle Aged; Substrate Specificity; Transfection

2008
Quantitative correlations among CYP3A sensitive substrates and inhibitors: literature analysis.
    Current drug metabolism, 2007, Volume: 8, Issue:8

    Topics: Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Databases, Factual; Drug Interactions; Enzyme Inhibitors; Erythromycin; Fluconazole; Ketoconazole; Midazolam; Substrate Specificity; Verapamil

2007
Predicting drug-drug interactions involving multiple mechanisms using physiologically based pharmacokinetic modeling: a case study with ruxolitinib.
    Clinical pharmacology and therapeutics, 2015, Volume: 97, Issue:2

    Topics: Cytochrome P-450 CYP3A Inducers; Cytochrome P-450 CYP3A Inhibitors; Digoxin; Drug Interactions; Erythromycin; Fasting; Fluconazole; Humans; Ketoconazole; Models, Biological; Nitriles; Prospective Studies; Pyrazoles; Pyrimidines; Retrospective Studies; Rifampin

2015
An illusion of septic shock: acute generalised exanthematous pustulosis with multiorgan dysfunction.
    BMJ case reports, 2017, Aug-02, Volume: 2017

    Topics: Acute Disease; Acute Generalized Exanthematous Pustulosis; Anti-Bacterial Agents; Anti-Inflammatory Agents; Diagnosis, Differential; Erythromycin; Fluconazole; Humans; Male; Methylprednisolone; Middle Aged; Multiple Organ Failure

2017
Development of Guanfacine Extended-Release Dosing Strategies in Children and Adolescents with ADHD Using a Physiologically Based Pharmacokinetic Model to Predict Drug-Drug Interactions with Moderate CYP3A4 Inhibitors or Inducers.
    Paediatric drugs, 2018, Volume: 20, Issue:2

    Topics: Adolescent; Adrenergic alpha-2 Receptor Agonists; Alkynes; Anti-Retroviral Agents; Antifungal Agents; Attention Deficit Disorder with Hyperactivity; Benzoxazines; Child; Cyclopropanes; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inducers; Cytochrome P-450 CYP3A Inhibitors; Delayed-Action Preparations; Drug Interactions; Erythromycin; Fluconazole; Guanfacine; Humans; Models, Biological

2018