Page last updated: 2024-08-21

erythromycin and dextromethorphan

erythromycin has been researched along with dextromethorphan in 12 studies

Research

Studies (12)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	3 (25.00)	18.2507
2000's	4 (33.33)	29.6817
2010's	5 (41.67)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Johans, C; Kinnunen, PK; Söderlund, T; Suomalainen, P	1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR	1
Chen, L; Fei, J; Mei, Y; Ren, S; Yan, SF; Zeng, J; Zhang, JZ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Littenberg, B; Smith, DS; Wheeler, M	1
Gorski, JC; Haehner, BD; Hall, SD; Jones, DR; O'Mara, EM	1
Barnas, CR; Gorski, JC; Krecic-Shepard, ME; Schwartz, JB; Slimko, J; Wainer, IW	1
Gillenwater, HH; Hamilton, G; Hawke, RL; LeCluyse, EL; Lindley, C; McCune, JS; Ritchie, J	1
Miller, JL; Trepanier, LA	1
Gelderblom, H; Guchelaar, HJ; Modak, AS; Opdam, FL	1

Reviews

2 review(s) available for erythromycin and dextromethorphan

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Breath tests to phenotype drug disposition in oncology. Clinical pharmacokinetics, 2013, Volume: 52, Issue:11 Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Antineoplastic Agents; Breath Tests; Cytochrome P-450 Enzyme System; Dextromethorphan; Dihydrouracil Dehydrogenase (NADP); Erythromycin; Humans; Neoplasms; Pantoprazole; Phenotype; Uracil	2013

Trials

3 trial(s) available for erythromycin and dextromethorphan

Article	Year
A randomized controlled trial of oral albuterol in acute cough. The Journal of family practice, 1996, Volume: 42, Issue:1 Topics: Acute Disease; Administration, Oral; Adrenergic beta-Agonists; Adult; Aged; Albuterol; Ambulatory Care; Antitussive Agents; Bronchitis; Cough; Dextromethorphan; Double-Blind Method; Drug Interactions; Drug Therapy, Combination; Erythromycin; Female; Humans; Male; Middle Aged; Prospective Studies	1996
Determination of cytochrome P450 3A4/5 activity in vivo with dextromethorphan N-demethylation. Clinical pharmacology and therapeutics, 1996, Volume: 60, Issue:4 Topics: Administration, Oral; Adolescent; Adult; Antitussive Agents; Cross-Over Studies; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Dextromethorphan; Drug Interactions; Erythromycin; Female; Humans; Male; Microsomes, Liver; Middle Aged; Mixed Function Oxygenases; Phenotype; Rifampin	1996
In vivo and in vitro induction of human cytochrome P4503A4 by dexamethasone. Clinical pharmacology and therapeutics, 2000, Volume: 68, Issue:4 Topics: Administration, Oral; Adult; Anti-Inflammatory Agents; Breath Tests; Cells, Cultured; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Dexamethasone; Dextromethorphan; Dose-Response Relationship, Drug; Drug Administration Schedule; Enzyme Induction; Erythromycin; Female; Glucocorticoids; Hepatocytes; Humans; Hydroxylation; In Vitro Techniques; Male; Mixed Function Oxygenases; Predictive Value of Tests; Reference Values; Testosterone	2000

Other Studies

7 other study(ies) available for erythromycin and dextromethorphan

Article	Year
Surface activity profiling of drugs applied to the prediction of blood-brain barrier permeability. Journal of medicinal chemistry, 2004, Mar-25, Volume: 47, Issue:7 Topics: Blood-Brain Barrier; Lipid Bilayers; Micelles; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship; Surface Properties	2004
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2). Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11 Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship	2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions. Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10 Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection	2012
Discovery and characterization of novel, potent, and selective cytochrome P450 2J2 inhibitors. Drug metabolism and disposition: the biological fate of chemicals, 2013, Volume: 41, Issue:1 Topics: Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Discovery; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Kinetics; Microsomes, Liver; Models, Molecular; Molecular Dynamics Simulation; Substrate Specificity	2013
In vivo comparison of putative probes of CYP3A4/5 activity: erythromycin, dextromethorphan, and verapamil. Clinical pharmacology and therapeutics, 1999, Volume: 66, Issue:1 Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Anti-Arrhythmia Agents; Anti-Bacterial Agents; Antitussive Agents; Area Under Curve; Breath Tests; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Dextromethorphan; Erythromycin; Female; Humans; Infusions, Intravenous; Linear Models; Male; Middle Aged; Mixed Function Oxygenases; Reference Values; Verapamil	1999
NADH-dependent reduction of sulphamethoxazole hydroxylamine in dog and human liver microsomes. Xenobiotica; the fate of foreign compounds in biological systems, 2000, Volume: 30, Issue:12 Topics: Adult; Animals; Anti-Infective Agents; Antibodies, Monoclonal; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Dextromethorphan; Dogs; Erythromycin; Female; Humans; Inactivation, Metabolic; Kinetics; Male; Microsomes, Liver; Middle Aged; NAD; Oxidation-Reduction; Oxidoreductases; Oxidoreductases, N-Demethylating; Protein Synthesis Inhibitors; Species Specificity; Sulfamethoxazole; Tolbutamide	2000