Page last updated: 2024-08-21

erythromycin and cyclosporine

erythromycin has been researched along with cyclosporine in 64 studies

Research

Studies (64)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	26 (40.63)	18.2507
2000's	19 (29.69)	29.6817
2010's	18 (28.13)	24.3611
2020's	1 (1.56)	2.80

Authors

Authors	Studies
Hasegawa, T; Hui, CS; Kitaichi, K; Miyamoto, KI; Sakai, M; Takagi, K; Wang, L; Yokogawa, K	1
Huang, L; Humphreys, JE; Morgan, JB; Polli, JW; Serabjit-Singh, CS; Webster, LO; Wring, SA	1
Dantzig, AH; Ekins, S; Kim, RB; Lan, LB; Leake, BF; Schuetz, EG; Schuetz, JD; Shepard, RL; Wikel, JH; Winter, MA; Wrighton, SA; Yasuda, K	1
Furuya, K; Lan, LB; Sanglard, D; Schuetz, EG; Schuetz, JD; Yasuda, K	1
Fischer, H; Huwyler, J; Poli, S; Schwab, D; Tabatabaei, A	1
Asakura, E; Hasegawa, T; Kitaichi, K; Miyoshi, M; Nadai, M; Nakayama, H; Shimizu, A; Sugie, M; Takagi, K; Zhao, YL	1
Li, Y; Li, YH; Wang, YH; Yang, L; Yang, SL	1
Lombardo, F; Obach, RS; Waters, NJ	1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM	1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM	1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Chen, X; Lin, X; Skolnik, S; Wang, J	1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K	1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V	1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR	1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Fent, K; Popovic, M; Smital, T; Zaja, R	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Blanco, MJ; Edmondson, Q; Furukawa, A; Handford, MJ; Hewitt, WM; Kelly, CN; Klein, VG; Lokey, RS; Ly, AM; Naylor, MR; Noland, RP; Pye, CR; Ramos, DP; Schwochert, J; Townsend, CE; Turmon, AC	1
Bauer, S; Brockmöller, J; Kewitz, H; Roots, I	1
Annesley, TM; Leichtman, AB; Normolle, DP; Smith, DE; Turgeon, DK; Watkins, PB	1
Lhoëst, G; Nickmilder, M; Verbeeck, R	1
Kolars, J; Lown, K; Merion, R; Turgeon, K; Watkins, PB; Wrighton, SA	1
Carruthers, SG; Freeman, DJ; Grant, DR	1
Cakaloglu, Y; Devlin, J; Tredger, JM; Williams, R	1
Benet, LZ; Gomez, DY; Gupta, SK; Hebert, MF; Rowland, M; Wacher, VJ; Wu, CY	1
Akagawa, KS; Keicho, N; Kudoh, S; Yotsumoto, H	1
Zylber-Katz, E	1
Jamal, SA; Murphy, GF; Siu, LL; Skorecki, KL; Tobe, SW; Warner, E	1
Deeb, GM; Leichtman, AB; Lown, KS; Merion, RM; Normolle, DP; Turgeon, DK; Watkins, PB	1
Bren, A; Kandus, A; Koselj, M; Kovac, D	1
Annesley, TM; Blake, DS; Leichtman, AB; Lown, KS; Schmouder, RL; Turgeon, DK; Watkins, PB	1
Sadrieh, N; Thomas, PE	1
Gonzalez, FJ; Korzekwa, KR; Nemec, J; Relling, MV; Schuetz, EG; Schuetz, JD	1
García-Valdecasas, JC; Grande, L; Moral, A; Navasa, M; Rimola, A; Rodés, J; Visa, J	1
Grevel, J; Kahan, BD; Napoli, KL; Serino, F; Strobel, HW	1
Collier, PS; Hughes, CM; Swanton, JG	1
Armstrong, D; Bernard, EM; Brown, ST; Edwards, FF; Tong, W	1
Kinirons, MT; Pincus, T; Stein, CM; Wilkinson, GR; Wood, AJ	1
Iwakawa, S; Komada, F; Ohba, M; Ohnishi, N; Okumura, K	1
Watkins, PB	1
Benet, LZ; Berg-Candolfi, M; Candolfi, E	1
Cline, MS; Cummings, OW; Filo, RS; Goldman, M; Pescovitz, MD	1
Bastien, MC; Demers, C; Gascon-Barré, M; Provencher, SJ; Villeneuve, JP	1
Gelfand, JM; Lebwohl, M; Tan, MH	1
Murakami, T; Nagai, J; Nasu, R; Sanemasa, M; Takano, M; Yumoto, R	1
De Vos, M; Depoortere, I; Lefebvre, R; Peeters, TL; Schoonjans, R; Van Vlem, B; Vanholder, R	1
Dalhoff, K; Kirkegaard, P; Rasmussen, A; Schmidt, LE	1
Liu, XD; Wang, GJ; Xie, L; Zhang, L	1
Asakura, E; Baba, K; Hasegawa, T; Kitaichi, K; Nadai, M; Sugie, M; Takagi, K; Torita, S; Zhao, YL	1
Karla, PK; Mitra, AK; Pal, D; Quinn, T	1
Hu, J; Liu, H; Liu, X; Wang, G; Xie, L	1
Das, T; Foroutan, P; Gatenby, RA; Gillies, RJ; Kam, Y; Martinez, G; Minton, S; Ruiz, E; Tian, H	1
Beumont, M; Monshouwer, M; Ouwerkerk-Mahadevan, S; Snoeys, J	1
Bromley, J; Schulze, R; Thacker, S; Thomas, L; Weng, M	1
Matsushima, N; Mendell, J; Parasrampuria, DA; Shi, M; Truitt, K; Zahir, H	1
Denny, JWL; Natkunarajah, J; Valiallah, N	1
Chen, J; Chen, L; Guo, S; Lei, J; Xu, P; Xu, T; Yu, L; Yu, X; Zhou, X; Zhu, S	1

Reviews

2 review(s) available for erythromycin and cyclosporine

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Clinically significant therapeutic interactions for the practicing dermatologist. Advances in dermatology, 1999, Volume: 14 Topics: Anti-Bacterial Agents; Antineoplastic Agents; Combined Modality Therapy; Cyclosporine; Dermatologic Agents; Dermatology; Drug Interactions; Erythromycin; Humans; Methotrexate; Photosensitizing Agents; Practice Patterns, Physicians'; Psoriasis; PUVA Therapy	1999

Trials

5 trial(s) available for erythromycin and cyclosporine

Article	Year
Vinblastine and erythromycin: an unrecognized serious drug interaction. Cancer chemotherapy and pharmacology, 1995, Volume: 35, Issue:3 Topics: Aged; Carcinoma, Renal Cell; Constipation; Cyclosporine; Drug Synergism; Drug Therapy, Combination; Erythromycin; Humans; Kidney Neoplasms; Lung Neoplasms; Lymphatic Metastasis; Male; Middle Aged; Muscle Spasticity; Neutropenia; Pain; Vinblastine	1995
Drug interactions between cyclosporine and rifampicin, erythromycin, and azoles in kidney recipients with opportunistic infections. Transplantation proceedings, 1994, Volume: 26, Issue:5 Topics: Adult; Antifungal Agents; Aspergillosis; Azoles; Candidiasis; Cyclosporine; Drug Interactions; Erythromycin; Female; Humans; Kidney Transplantation; Legionnaires' Disease; Male; Middle Aged; Opportunistic Infections; Postoperative Complications; Rifampin; Streptococcal Infections; Tuberculosis, Pulmonary	1994
Prediction of interpatient and intrapatient variation in OG 37-325 dosing requirements by the erythromycin breath test. A prospective study in renal transplant recipients. Transplantation, 1994, Jun-27, Volume: 57, Issue:12 Topics: Adult; Breath Tests; Cyclosporine; Cyclosporins; Dose-Response Relationship, Drug; Erythromycin; Female; Humans; Immunosuppressive Agents; Kidney Diseases; Kidney Transplantation; Male; Middle Aged; Patient Compliance; Predictive Value of Tests; Regression Analysis	1994
Relationship between postoperative erythromycin breath test and early morbidity in liver transplant recipients. Transplantation, 2003, Jul-27, Volume: 76, Issue:2 Topics: Adult; Anti-Bacterial Agents; Aryl Hydrocarbon Hydroxylases; Breath Tests; Cyclosporine; Cytochrome P-450 CYP3A; Erythromycin; Female; Graft Rejection; Graft Survival; Humans; Immunosuppressive Agents; Kidney Diseases; Liver; Liver Transplantation; Male; Middle Aged; Oxidoreductases, N-Demethylating; Postoperative Complications; Predictive Value of Tests; Tacrolimus	2003
Edoxaban drug-drug interactions with ketoconazole, erythromycin, and cyclosporine. British journal of clinical pharmacology, 2016, Volume: 82, Issue:6 Topics: Administration, Oral; Adolescent; Adult; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cross-Over Studies; Cyclosporine; Cytochrome P-450 CYP3A; Drug Administration Schedule; Drug Interactions; Erythromycin; Factor Xa Inhibitors; Healthy Volunteers; Humans; Ketoconazole; Metabolic Clearance Rate; Middle Aged; Pyridines; Substrate Specificity; Thiazoles; Young Adult	2016

Other Studies

57 other study(ies) available for erythromycin and cyclosporine

Article	Year
Reversal of anticancer drug resistance by macrolide antibiotics in vitro and in vivo. Clinical and experimental pharmacology & physiology, 2000, Volume: 27, Issue:8 Topics: Animals; Anti-Bacterial Agents; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Calcium Channel Blockers; Cell Membrane; Cell Survival; Cyclosporine; Drug Resistance, Neoplasm; Immunosuppressive Agents; Leukemia P388; Macrolides; Mice; Neoplasm Transplantation; Tumor Cells, Cultured; Verapamil; Vinblastine	2000
Rational use of in vitro P-glycoprotein assays in drug discovery. The Journal of pharmacology and experimental therapeutics, 2001, Volume: 299, Issue:2 Topics: Adenosine Triphosphatases; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cells, Cultured; Chromatography, Liquid; Enzyme Inhibitors; Fluoresceins; Fluorescent Dyes; Humans; Mass Spectrometry; Pharmacology; Spodoptera	2001
Three-dimensional quantitative structure-activity relationships of inhibitors of P-glycoprotein. Molecular pharmacology, 2002, Volume: 61, Issue:5 Topics: Animals; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Caco-2 Cells; Ergonovine; Fluoxetine; Humans; Models, Molecular; Oxytocics; Protein Conformation; Selective Serotonin Reuptake Inhibitors; Structure-Activity Relationship; Swine; Transfection; Vinblastine	2002
Interaction of cytochrome P450 3A inhibitors with P-glycoprotein. The Journal of pharmacology and experimental therapeutics, 2002, Volume: 303, Issue:1 Topics: Animals; Aryl Hydrocarbon Hydroxylases; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Cell Line; Cells, Cultured; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dihydroergocryptine; Drug Interactions; Enzyme Inhibitors; Fluconazole; Humans; Mice; Mice, Knockout; Microsomes, Liver; Oxidoreductases, N-Demethylating; Recombinant Proteins; Reserpine; Swine; Tissue Distribution; Transfection; Vinblastine	2002
Comparison of in vitro P-glycoprotein screening assays: recommendations for their use in drug discovery. Journal of medicinal chemistry, 2003, Apr-24, Volume: 46, Issue:9 Topics: Adenosine Triphosphatases; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Cells, Cultured; Drug Evaluation, Preclinical; Fluoresceins; Fluorescent Dyes; Humans; Indicators and Reagents; Mice; Models, Molecular; Rhodamines; Species Specificity; Swine	2003
Azithromycin reverses anticancer drug resistance and modifies hepatobiliary excretion of doxorubicin in rats. European journal of pharmacology, 2004, Jan-26, Volume: 484, Issue:2-3 Topics: Animals; Antibiotics, Antineoplastic; Azithromycin; Bile; Bile Ducts; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance, Neoplasm; Humans; Intracellular Fluid; K562 Cells; Liver; Male; Rats; Rats, Sprague-Dawley	2004
Modeling K(m) values using electrotopological state: substrates for cytochrome P450 3A4-mediated metabolism. Bioorganic & medicinal chemistry letters, 2005, Sep-15, Volume: 15, Issue:18 Topics: Computational Biology; Cyclohexanols; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Molecular Structure; Principal Component Analysis; Pyrrolizidine Alkaloids; Quantitative Structure-Activity Relationship; Reproducibility of Results; Substrate Specificity; Venlafaxine Hydrochloride	2005
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2). Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11 Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship	2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19 Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship	2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21 Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
Attenuation of intestinal absorption by major efflux transporters: quantitative tools and strategies using a Caco-2 model. Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:2 Topics: Adenosine; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Sub-Family B Member 4; ATP-Binding Cassette Transporters; Biological Transport; Caco-2 Cells; Chromatography, Liquid; Dibenzocycloheptenes; Diketopiperazines; Drug Discovery; Heterocyclic Compounds, 4 or More Rings; Humans; Intestinal Absorption; Mass Spectrometry; Models, Biological; Neoplasm Proteins; Pharmaceutical Preparations; Predictive Value of Tests; Propionates; Quinolines; Substrate Specificity	2011
QSAR-based permeability model for drug-like compounds. Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8 Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2011
FDA-approved drug labeling for the study of drug-induced liver injury. Drug discovery today, 2011, Volume: 16, Issue:15-16 Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration	2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions. Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10 Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection	2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10 Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding	2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Molecular characterization of zebrafish Oatp1d1 (Slco1d1), a novel organic anion-transporting polypeptide. The Journal of biological chemistry, 2013, Nov-22, Volume: 288, Issue:47 Topics: Animals; Evolution, Molecular; Glycosylation; Gonadal Steroid Hormones; HEK293 Cells; Humans; Ion Transport; Organic Anion Transporters; Protein Multimerization; Zebrafish; Zebrafish Proteins	2013
Lipophilic Permeability Efficiency Reconciles the Opposing Roles of Lipophilicity in Membrane Permeability and Aqueous Solubility. Journal of medicinal chemistry, 2018, 12-27, Volume: 61, Issue:24 Topics: 1-Octanol; Cell Membrane Permeability; Cyclosporins; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Peptides; Peptides, Cyclic; Pharmaceutical Preparations; Small Molecule Libraries; Solubility; Structure-Activity Relationship; Water	2018
The effect of the new immunosuppressive drug FK506 on the formation of secondary metabolites of cyclosporin A. International journal of clinical pharmacology, therapy, and toxicology, 1992, Volume: 30, Issue:11 Topics: Biotransformation; Cyclosporine; Diltiazem; Erythromycin; Humans; Immunosuppressive Agents; In Vitro Techniques; Microsomes, Liver; Tacrolimus	1992
Erythromycin breath test predicts oral clearance of cyclosporine in kidney transplant recipients. Clinical pharmacology and therapeutics, 1992, Volume: 52, Issue:5 Topics: Adult; Breath Tests; Carbon Dioxide; Carbon Radioisotopes; Cyclosporine; Cytochrome P-450 Enzyme System; Erythromycin; Female; Humans; Kidney Transplantation; Male; Middle Aged; Steroid Hydroxylases	1992
Isolation and mass spectrometric identification of cyclosporin A isomeric dihydrodiol precursors from erythromycin-induced rabbit liver microsomes. Pharmaceutica acta Helvetiae, 1992, Volume: 67, Issue:9-10 Topics: Animals; Chromatography, High Pressure Liquid; Cyclosporine; Erythromycin; In Vitro Techniques; Isomerism; Male; Mass Spectrometry; Microsomes, Liver; Rabbits	1992
The erythromycin breath test selectively measures P450IIIA in patients with severe liver disease. Clinical pharmacology and therapeutics, 1992, Volume: 51, Issue:3 Topics: Aryl Hydrocarbon Hydroxylases; Breath Tests; Carbon Dioxide; Carbon Radioisotopes; Cyclosporine; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Erythromycin; Female; Humans; Liver Diseases; Male; Microsomes, Liver; Oxidoreductases, N-Demethylating	1992
The cyclosporin-erythromycin interaction: impaired first pass metabolism in the pig. British journal of pharmacology, 1991, Volume: 103, Issue:3 Topics: Animals; Chromatography, High Pressure Liquid; Cyclosporine; Drug Interactions; Erythromycin; Female; Half-Life; Swine	1991
Importance of cytochrome P-450IIIA activity in determining dosage and blood levels of FK 506 and cyclosporine in liver transplant recipients. Hepatology (Baltimore, Md.), 1994, Volume: 20, Issue:2 Topics: Aryl Hydrocarbon Hydroxylases; Breath Tests; Cyclosporine; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Erythromycin; Female; Humans; Lidocaine; Liver Transplantation; Male; Oxidoreductases, N-Demethylating; Predictive Value of Tests; Regression Analysis; Tacrolimus	1994
Differentiation of absorption and first-pass gut and hepatic metabolism in humans: studies with cyclosporine. Clinical pharmacology and therapeutics, 1995, Volume: 58, Issue:5 Topics: Administration, Oral; Biological Availability; Cyclosporine; Drug Interactions; Erythromycin; Humans; Immunosuppressive Agents; Injections, Intravenous; Intestinal Absorption; Intestinal Mucosa; Ketoconazole; Kidney Transplantation; Liver; Protein Synthesis Inhibitors; Rifampin	1995
Antilymphocytic activity of erythromycin distinct from that of FK506 or cyclosporin A. The Journal of antibiotics, 1993, Volume: 46, Issue:9 Topics: Antigens; Cell Line; Concanavalin A; Cyclosporine; Drug Synergism; Erythromycin; Humans; Immunosuppressive Agents; Interleukin-2; Lymphocyte Activation; Lymphocytes; Motilin; Receptors, Interleukin-2; Tacrolimus; Tumor Cells, Cultured	1993
Multiple drug interactions with cyclosporine in a heart transplant patient. The Annals of pharmacotherapy, 1995, Volume: 29, Issue:2 Topics: Cyclosporine; Drug Interactions; Drug Monitoring; Erythromycin; Heart Transplantation; Humans; Immunosuppression Therapy; Isoniazid; Male; Middle Aged; Rifampin	1995
P450 3A activity and cyclosporine dosing in kidney and heart transplant recipients. Clinical pharmacology and therapeutics, 1994, Volume: 56, Issue:3 Topics: Adult; Breath Tests; Cyclosporine; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme System; Drug Administration Schedule; Erythromycin; Female; Heart Transplantation; Humans; Kidney Transplantation; Male; Middle Aged; Mixed Function Oxygenases; Prospective Studies; Regression Analysis	1994
Characterization of rat cytochrome P450 isozymes involved in the covalent binding of cyclosporin A to microsomal proteins. Toxicology and applied pharmacology, 1994, Volume: 127, Issue:2 Topics: Aging; Animals; Antibodies, Monoclonal; Aryl Hydrocarbon Hydroxylases; Blotting, Western; Catalysis; Cyclosporine; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Induction; Erythromycin; Female; Glutathione; Isoenzymes; Kidney; Male; Mannitol; Microsomes; Microsomes, Liver; Oxidoreductases, N-Demethylating; Protein Binding; Proteins; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Testosterone; Tritium; Troleandomycin	1994
O-demethylation of epipodophyllotoxins is catalyzed by human cytochrome P450 3A4. Molecular pharmacology, 1994, Volume: 45, Issue:2 Topics: Biotransformation; Catalysis; Catechols; Chromatography, High Pressure Liquid; Cyclosporine; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dexamethasone; Erythromycin; Etoposide; Humans; Methylation; Microsomes, Liver; Midazolam; Mixed Function Oxygenases; Teniposide	1994
Erythromycin ototoxicity in liver transplant patients. Transplant international : official journal of the European Society for Organ Transplantation, 1994, Volume: 7, Issue:1 Topics: Adult; Cyclosporine; Drug Interactions; Erythromycin; Female; Hearing Loss, Bilateral; Humans; Liver Transplantation; Male; Middle Aged; Respiratory Tract Infections	1994
Generation of oxygen free radicals during the metabolism of cyclosporine A: a cause-effect relationship with metabolism inhibition. Molecular and cellular biochemistry, 1993, May-26, Volume: 122, Issue:2 Topics: Aminopyrine; Animals; Carbon Tetrachloride; Catalase; Chloramphenicol; Cyclosporine; Cytochrome P-450 Enzyme System; Erythromycin; Free Radicals; Ketoconazole; Lipid Peroxidation; Male; Proadifen; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Superoxide Dismutase	1993
Cyclosporin A and erythromycin: a study of a drug interaction in the in situ perfused rat liver model. Biopharmaceutics & drug disposition, 1993, Volume: 14, Issue:7 Topics: Animals; Bile; Cyclosporine; Cyclosporins; Drug Interactions; Erythromycin; Humans; Liver; Male; Metabolic Clearance Rate; Perfusion; Rats; Rats, Sprague-Dawley	1993
Azithromycin, rifabutin, and rifapentine for treatment and prophylaxis of Mycobacterium avium complex in rats treated with cyclosporine. Antimicrobial agents and chemotherapy, 1993, Volume: 37, Issue:3 Topics: Animals; Antitubercular Agents; Azithromycin; Cyclosporine; Erythromycin; Male; Mycobacterium avium-intracellulare Infection; Rats; Rats, Sprague-Dawley; Rifabutin; Rifampin; Rifamycins; Tissue Distribution	1993
Comparison of the dapsone recovery ratio and the erythromycin breath test as in vivo probes of CYP3A activity in patients with rheumatoid arthritis receiving cyclosporine. Clinical pharmacology and therapeutics, 1996, Volume: 59, Issue:1 Topics: Adult; Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Breath Tests; Carbon Radioisotopes; Cyclosporine; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme System; Dapsone; Erythromycin; Female; Humans; Male; Middle Aged; Mixed Function Oxygenases; Predictive Value of Tests; Protein Synthesis Inhibitors	1996
Effect of clarithromycin on the bioavailability of cyclosporin in rats. Biological & pharmaceutical bulletin, 1996, Volume: 19, Issue:5 Topics: Administration, Oral; Animals; Anti-Bacterial Agents; Biological Availability; Clarithromycin; Cyclosporine; Cyclosporins; Drug Interactions; Erythromycin; Gastric Emptying; Infusions, Intravenous; Male; Rats; Rats, Wistar	1996
Erythromycin breath test and clinical transplantation. Therapeutic drug monitoring, 1996, Volume: 18, Issue:4 Topics: Breath Tests; Carbon Dioxide; Carbon Radioisotopes; Cyclosporine; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Erythromycin; Genetic Variation; Humans; Liver; Mixed Function Oxygenases; Organ Transplantation; Protein Synthesis Inhibitors	1996
Suppression of intestinal and hepatic cytochrome P4503A in murine Toxoplasma infection. Effects of N-acetylcysteine and N(G)-monomethyl-L-arginine on the hepatic suppression. Xenobiotica; the fate of foreign compounds in biological systems, 1996, Volume: 26, Issue:4 Topics: Acetylcysteine; Animals; Antibodies, Monoclonal; Arginine; Aryl Hydrocarbon Hydroxylases; Cyclosporine; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Erythromycin; Interferon-gamma; Intestinal Mucosa; Jejunum; Macrophages, Peritoneal; Male; Mice; Mice, Inbred CBA; Microsomes; Microsomes, Liver; Nitrites; Oxidoreductases, N-Demethylating; Toxoplasmosis, Animal	1996
Bacillary angiomatosis in a renal transplant recipient. Transplantation, 1999, Jan-27, Volume: 67, Issue:2 Topics: Adult; Angiomatosis, Bacillary; Anti-Bacterial Agents; Cyclosporine; Erythromycin; Humans; Immunosuppressive Agents; Kidney Transplantation; Male; Mycophenolic Acid; Prednisone; Skin	1999
Effect of cyclosporine A on cytochrome P-450-mediated drug metabolism in the partially hepatectomized rat. Drug metabolism and disposition: the biological fate of chemicals, 1999, Volume: 27, Issue:4 Topics: Aminopyrine; Animals; Biotransformation; Blotting, Northern; Caffeine; Carbon Radioisotopes; Cyclosporine; Cytochrome P-450 Enzyme System; Enzyme Activation; Erythromycin; Hepatectomy; Isoenzymes; Liver Regeneration; Male; Rats; Rats, Sprague-Dawley; RNA, Messenger; Substrate Specificity	1999
Pharmacokinetic interaction of cytochrome P450 3A-related compounds with rhodamine 123, a P-glycoprotein substrate, in rats pretreated with dexamethasone. Drug metabolism and disposition: the biological fate of chemicals, 2001, Volume: 29, Issue:2 Topics: Animals; Aryl Hydrocarbon Hydroxylases; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biliary Tract; Blotting, Western; Cyclosporine; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Dexamethasone; Drug Interactions; Erythromycin; Intestinal Absorption; Intestines; Liver; Male; Midazolam; Oxidoreductases, N-Demethylating; Rats; Rats, Wistar; Rhodamine 123; Substrate Specificity; Verapamil	2001
In vitro evaluation of motilin agonism by macrolide immunosuppressive drugs. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2002, Volume: 17, Issue:6 Topics: Animals; Carbachol; Cyclosporine; Duodenum; Electric Stimulation; Erythromycin; Immunosuppressive Agents; In Vitro Techniques; Kinetics; Male; Motilin; Muscle Contraction; Muscle, Smooth; Rabbits; Sirolimus; Tacrolimus	2002
P-glycoprotein restricted transport of nimodipine across blood-brain barrier. Acta pharmacologica Sinica, 2003, Volume: 24, Issue:9 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood-Brain Barrier; Calcium Channel Blockers; Capillaries; Cells, Cultured; Cerebral Cortex; Cyclosporine; Drug Resistance, Multiple; Endothelium, Vascular; Erythromycin; Nimodipine; Rats; Rats, Nude; Rats, Sprague-Dawley	2003
Possible involvement of the drug transporters P glycoprotein and multidrug resistance-associated protein Mrp2 in disposition of azithromycin. Antimicrobial agents and chemotherapy, 2004, Volume: 48, Issue:3 Topics: Animals; Anti-Bacterial Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azithromycin; Bile; Cyclosporine; Erythromycin; Hyperbilirubinemia; Immunosuppressive Agents; Intestinal Mucosa; Kidney; Liver; Male; Mitochondrial Proteins; Probenecid; Rats; Rats, Sprague-Dawley; Rats, Wistar; Renal Agents; Ribosomal Proteins; Saccharomyces cerevisiae Proteins; Tissue Distribution	2004
Molecular evidence and functional expression of a novel drug efflux pump (ABCC2) in human corneal epithelium and rabbit cornea and its role in ocular drug efflux. International journal of pharmaceutics, 2007, May-04, Volume: 336, Issue:1 Topics: Animals; Biological Transport; Cell Line; Cell Membrane; Cells, Cultured; Cornea; Cyclosporine; Dogs; Epithelial Cells; Epithelium, Corneal; Erythromycin; Gene Expression; Humans; Male; Membrane Transport Proteins; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Pharmaceutical Preparations; Propionates; Quinolines; Rabbits	2007
Possible multiple transporters were involved in hepatobiliary excretion of antofloxacin in rats. Xenobiotica; the fate of foreign compounds in biological systems, 2007, Volume: 37, Issue:6 Topics: Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Bile; Biological Transport; Cimetidine; Cyclosporine; Diclofenac; Enzyme Inhibitors; Erythromycin; Liver; Male; Membrane Transport Proteins; Ofloxacin; Probenecid; Rats; Rats, Sprague-Dawley; Uricosuric Agents	2007
Sweat but no gain: inhibiting proliferation of multidrug resistant cancer cells with "ersatzdroges". International journal of cancer, 2015, Feb-15, Volume: 136, Issue:4 Topics: Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B; Cell Proliferation; Cell Survival; Clarithromycin; Cyclosporine; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Erythromycin; Female; Gene Expression; Humans; Mammary Neoplasms, Experimental; MCF-7 Cells; Mice, Nude; Molecular Targeted Therapy; Tumor Burden; Verapamil; Xenograft Model Antitumor Assays	2015
Mechanistic understanding of the nonlinear pharmacokinetics and intersubject variability of simeprevir: A PBPK-guided drug development approach. Clinical pharmacology and therapeutics, 2016, Volume: 99, Issue:2 Topics: Alkynes; Antiviral Agents; Benzoxazines; Cyclopropanes; Cyclosporine; Cytochrome P-450 CYP3A; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Erythromycin; Hepatitis C; Humans; Liver; Liver-Specific Organic Anion Transporter 1; Nonlinear Dynamics; Organic Anion Transporters; Rifampin; Ritonavir; Simeprevir; Viral Nonstructural Proteins	2016
Ophthalmic Considerations in Stevens-Johnson Syndrome. The Journal of pediatrics, 2016, Volume: 175 Topics: Adolescent; Anti-Bacterial Agents; Biological Dressings; Conjunctivitis; Cyclosporine; Erythromycin; Glucocorticoids; Humans; Immunosuppressive Agents; Male; Prednisolone; Stevens-Johnson Syndrome	2016
'It's hard to swallow'. Clinical and experimental dermatology, 2018, Volume: 43, Issue:8 Topics: Anti-Bacterial Agents; Capsules; Cyclosporine; Deglutition; Deglutition Disorders; Dermatologic Agents; Erythromycin; Humans; Isotretinoin; Lymecycline; Methotrexate; Tablets	2018
Metabolic interactions between flumatinib and the CYP3A4 inhibitors erythromycin, cyclosporine, and voriconazole. Die Pharmazie, 2020, 09-01, Volume: 75, Issue:9 Topics: Aminopyridines; Animals; Benzamides; Cyclosporine; Cytochrome P-450 CYP3A Inhibitors; Drug Interactions; Erythromycin; Female; Humans; Male; Protein Kinase Inhibitors; Rats; Rats, Sprague-Dawley; Voriconazole	2020