Compounds > erythromycin
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erythromycin and aminopyrine

erythromycin has been researched along with aminopyrine in 14 studies

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19901 (7.14)18.7374
1990's6 (42.86)18.2507
2000's3 (21.43)29.6817
2010's4 (28.57)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Honda, K; Izumi, T; Miyaji, Y; Nakayama, S; Okazaki, O; Okudaira, N; Shiosakai, K; Sugiyama, D; Suzuki, W; Takakusa, H; Watanabe, A1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Kolars, JC; Murray, SA; Peters, KM; Watkins, PB1
Trzaski, M1
Grevel, J; Kahan, BD; Napoli, KL; Serino, F; Strobel, HW1
Tanaka, E; Yasuhara, H1
Breimer, DD; Tanaka, E1
Bastien, MC; Demers, C; Gascon-Barré, M; Provencher, SJ; Villeneuve, JP1
Chen, JH; Ding, H; Kong, R; Li, QX; Peng, RX; Wang, H; Yu, JP; Zhang, YH1
Grand, F; Guitton, J; Kilinc, I; Sarkis, A1
Hu, K; Li, D; Lin, M; Yang, XL; Yu, WJ; Zhang, SJ1

Reviews

2 review(s) available for erythromycin and aminopyrine

ArticleYear
[Evaluation of liver function in liver diseases using drugs as indicators].
    The Journal of toxicological sciences, 1997, Volume: 22, Issue:3

    Topics: Aminopyrine; Antipyrine; Erythromycin; Humans; Lidocaine; Liver; Liver Diseases; Liver Function Tests; Trimethadione

1997
In vivo function tests of hepatic drug-oxidizing capacity in patients with liver disease.
    Journal of clinical pharmacy and therapeutics, 1997, Volume: 22, Issue:4

    Topics: Aminopyrine; Antipyrine; Breath Tests; Caffeine; Chlorzoxazone; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme System; Erythromycin; Humans; Liver Diseases; Liver Function Tests; Trimethadione

1997

Other Studies

12 other study(ies) available for erythromycin and aminopyrine

ArticleYear
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
    Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19

    Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
Combination of GSH trapping and time-dependent inhibition assays as a predictive method of drugs generating highly reactive metabolites.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:7

    Topics: Glutathione; Pharmacology; Sulfur Radioisotopes

2011
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Differential regulation of liver P-450III cytochromes in choline-deficient rats: implications for the erythromycin breath test as a parameter of liver function.
    Hepatology (Baltimore, Md.), 1990, Volume: 12, Issue:6

    Topics: Aminopyrine; Animals; Blotting, Northern; Breath Tests; Choline Deficiency; Cytochrome P-450 Enzyme System; Erythromycin; Female; Immunoblotting; Liver; Liver Cirrhosis, Experimental; Liver Function Tests; Male; Microsomes, Liver; Nucleic Acid Hybridization; Oxidoreductases, N-Demethylating; Rats; Rats, Inbred Strains; RNA, Messenger

1990
[Effect of various drugs in vivo and in vitro on the results of the most frequently performed enzymatic determinations in a clinical laboratory].
    Folia medica Cracoviensia, 1980, Volume: 22, Issue:3-4

    Topics: Alanine Transaminase; Alkaline Phosphatase; Aminopyrine; Amylases; Antipyrine; Ascorbic Acid; Aspartate Aminotransferases; Chlorpropamide; Clinical Enzyme Tests; Diazepam; Drug Combinations; Enzyme Activation; Enzyme Inhibitors; Erythromycin; Female; Humans; In Vitro Techniques; L-Lactate Dehydrogenase; Male; Pemoline; Phenylbutazone; Poland; Salicylates

1980
Generation of oxygen free radicals during the metabolism of cyclosporine A: a cause-effect relationship with metabolism inhibition.
    Molecular and cellular biochemistry, 1993, May-26, Volume: 122, Issue:2

    Topics: Aminopyrine; Animals; Carbon Tetrachloride; Catalase; Chloramphenicol; Cyclosporine; Cytochrome P-450 Enzyme System; Erythromycin; Free Radicals; Ketoconazole; Lipid Peroxidation; Male; Proadifen; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Superoxide Dismutase

1993
Effect of cyclosporine A on cytochrome P-450-mediated drug metabolism in the partially hepatectomized rat.
    Drug metabolism and disposition: the biological fate of chemicals, 1999, Volume: 27, Issue:4

    Topics: Aminopyrine; Animals; Biotransformation; Blotting, Northern; Caffeine; Carbon Radioisotopes; Cyclosporine; Cytochrome P-450 Enzyme System; Enzyme Activation; Erythromycin; Hepatectomy; Isoenzymes; Liver Regeneration; Male; Rats; Rats, Sprague-Dawley; RNA, Messenger; Substrate Specificity

1999
Demethylation capacity of human fetal adrenal mitochondrial cytochrome P-450 in vitro.
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1999, Volume: 20, Issue:4

    Topics: Adrenal Glands; Aminopyrine; Benzphetamine; Cytochrome P-450 Enzyme System; Erythromycin; Fetus; Formaldehyde; Humans; Microsomes, Liver; Mitochondria; Troleandomycin

1999
Application of isotopic ratio mass spectrometry for the in vitro determination of demethylation activity in human liver microsomes using N-methyl-13C-labeled substrates.
    Analytical biochemistry, 2002, Jul-15, Volume: 306, Issue:2

    Topics: Aminopyrine; Caffeine; Carbon Isotopes; Cytochrome P-450 Enzyme System; Erythromycin; Humans; In Vitro Techniques; Mass Spectrometry; Methylation; Microsomes, Liver; Oxidoreductases, N-Demethylating

2002
Effects of mammalian CYP3A inducers on CYP3A-related enzyme activities in grass carp (Ctenopharyngodon idellus): Possible implications for the establishment of a fish CYP3A induction model.
    Comparative biochemistry and physiology. Toxicology & pharmacology : CBP, 2008, Volume: 147, Issue:1

    Topics: Aminopyrine; Aminopyrine N-Demethylase; Animals; Aryl Hydrocarbon Hydroxylases; Bass; Carps; Cell Culture Techniques; Cell Line; Cytochrome P-450 CYP3A; Dexamethasone; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Induction; Erythromycin; Fish Proteins; Hepatocytes; Kidney; Kinetics; Liver; Microsomes, Liver; Models, Animal; Phenobarbital; Rifampin; Steroid Hydroxylases; Substrate Specificity; Testosterone

2008