Page last updated: 2024-09-02

erythromycin 2'-acetate and erythromycin

erythromycin 2'-acetate has been researched along with erythromycin in 26 studies

Compound Research Comparison

Studies
(erythromycin 2'-acetate)
Trials
(erythromycin 2'-acetate)
Recent Studies (post-2010)
(erythromycin 2'-acetate)
Studies
(erythromycin)
Trials
(erythromycin)
Recent Studies (post-2010) (erythromycin)
2714014,5241,1381,926

Protein Interaction Comparison

ProteinTaxonomyerythromycin 2'-acetate (IC50)erythromycin (IC50)
30S ribosomal protein S6Escherichia coli K-121.156
30S ribosomal protein S7Escherichia coli K-121.156
50S ribosomal protein L15Escherichia coli K-121.156
Cytochrome P450 3A4Homo sapiens (human)1.045
50S ribosomal protein L10Escherichia coli K-121.156
50S ribosomal protein L11Escherichia coli K-121.156
50S ribosomal protein L7/L12Escherichia coli K-121.156
50S ribosomal protein L19Escherichia coli K-121.156
50S ribosomal protein L1Escherichia coli K-121.156
50S ribosomal protein L20Escherichia coli K-121.156
50S ribosomal protein L27Escherichia coli K-121.156
50S ribosomal protein L28Escherichia coli K-121.156
50S ribosomal protein L29Escherichia coli K-121.156
50S ribosomal protein L31Escherichia coli K-121.156
50S ribosomal protein L31 type BEscherichia coli K-121.156
50S ribosomal protein L32Escherichia coli K-121.156
50S ribosomal protein L33Escherichia coli K-121.156
50S ribosomal protein L34Escherichia coli K-121.156
50S ribosomal protein L35Escherichia coli K-121.156
50S ribosomal protein L36Escherichia coli K-121.156
30S ribosomal protein S10Escherichia coli K-121.156
30S ribosomal protein S11Escherichia coli K-121.156
30S ribosomal protein S12Escherichia coli K-121.156
30S ribosomal protein S13Escherichia coli K-121.156
30S ribosomal protein S16Escherichia coli K-121.156
30S ribosomal protein S18Escherichia coli K-121.156
30S ribosomal protein S19Escherichia coli K-121.156
30S ribosomal protein S20Escherichia coli K-121.156
30S ribosomal protein S2Escherichia coli K-121.156
30S ribosomal protein S3Escherichia coli K-121.156
30S ribosomal protein S4Escherichia coli K-121.156
30S ribosomal protein S5Escherichia coli K-121.156
30S ribosomal protein S8Escherichia coli K-121.156
30S ribosomal protein S9Escherichia coli K-121.156
50S ribosomal protein L13Escherichia coli K-121.156
50S ribosomal protein L14Escherichia coli K-121.156
50S ribosomal protein L16Escherichia coli K-121.156
50S ribosomal protein L23Escherichia coli K-121.156
30S ribosomal protein S15Escherichia coli K-121.156
50S ribosomal protein L17Escherichia coli K-121.156
50S ribosomal protein L21Escherichia coli K-121.156
50S ribosomal protein L30Escherichia coli K-121.156
50S ribosomal protein L6Escherichia coli K-121.156
30S ribosomal protein S14Escherichia coli K-121.156
30S ribosomal protein S17Escherichia coli K-121.156
30S ribosomal protein S1Escherichia coli K-121.156
50S ribosomal protein L18Escherichia coli K-121.156
50S ribosomal protein L2Escherichia coli K-121.156
50S ribosomal protein L3Escherichia coli K-121.156
50S ribosomal protein L24Escherichia coli K-121.156
50S ribosomal protein L4Escherichia coli K-121.156
50S ribosomal protein L22Escherichia coli K-121.156
50S ribosomal protein L5Escherichia coli K-121.156
30S ribosomal protein S21Escherichia coli K-121.156
50S ribosomal protein L25Escherichia coli K-121.156
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)0.039
50S ribosomal protein L36 2Escherichia coli K-121.156

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-199015 (57.69)18.7374
1990's10 (38.46)18.2507
2000's1 (3.85)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Haataja, H; Järvinen, A; Mattila, J; Nykänen, S1
Marvola, M; Nokelainen, M; Nykänen, S1
Lankinen, KS; Lehtonen, L; Rita, H; Salmi, HA; Valtonen, V; Wikberg, R1
Gordin, A; Kokkonen, P; Lehtinen, R; Peltola, J; Pohto, P; Tuominen, RK; Wikberg, R1
Anttila, M; Laakso, S; Scheinin, M1
Gordin, A; Kaukoranta-Tolvanen, SS; Männistö, PT; Renkonen, OV; Tamm, L1
Hanhijärvi, H; Havas, A; Komulainen, H; Männistö, PT; Rauramaa, V; Vuorela, A1
Allonen, H; Elonen, E; Roos, L; Saloranta, P1
Korkeala, H; Männistö, PT1
Antikainen, R; Gordin, A; Kokkonen, P; Männistö, PT; Rauramaa, V; Savolainen, S; Ylikoski, J1
Antikainen, R; Brandt, H; Gordin, A; Salo, OP1
Flygare, U; Hildén, M; Hurme, J; Järvinen, H; Leskinen, J; Pynnönen, S; Riikonen, A; Salomaa, V; Seuri, M; Wuolijoki, E1
Antikainen, R; Gordin, A; Rostila, T; Visa, K1
Männistö, PT; Pohto, P; Solkinen, A; Tuominen, RK; Vuorela, A1
Haataja, H; Männistö, PT; Pohto, P; Solkinen, A; Tuominen, RK; Vuorela, A1
Haataja, H; Kokkonen, P1
Antikainen, R; Gordin, A; Haataja, H; Männistö, PT; Savolainen, S; Tuominen, RK; Ylikoski, J1
Antikainen, R; Gordin, A; Hulmi, S; Kalima, S; Mäkelä, P1
Collan, Y; Hanhijärvi, H; Husband, RF; Kosma, VM; Männistö, PT; Viluksela, M1
Antikainen, R; Gordin, A; Salmi, HA1
Lehtonen, L; Wiesner, B; Wilen-Rosenqvist, G1
Karhunen, M; Kokkonen, P; Lehtonen, L; Tuominen, R; Wikberg, R1
Kiesvaara, J; Niskanen, T; Riippi, M; Yliruusi, J1
Antikainen, O; Niskanen, T; Riippi, M; Yliruusi, J1
Järvinen, T; Niemi, R; Rautio, J1
Riippi, M; Tanninen, V; Yliruusi, J1

Trials

13 trial(s) available for erythromycin 2'-acetate and erythromycin

ArticleYear
Effect of food on absorption and hydrolysis of erythromycin acistrate.
    Arzneimittel-Forschung, 1992, Volume: 42, Issue:1

    Topics: Adult; Biological Availability; Chromatography, High Pressure Liquid; Erythromycin; Female; Food; Humans; Hydrolysis; Intestinal Absorption; Male; Tablets, Enteric-Coated

1992
Hepatic safety of erythromycin acistrate in 1549 patients with respiratory tract or skin infections.
    The Journal of antimicrobial chemotherapy, 1991, Volume: 27, Issue:2

    Topics: Adolescent; Adult; Aged; Alanine Transaminase; Alkaline Phosphatase; Aspartate Aminotransferases; Eating; Erythromycin; Female; gamma-Glutamyltransferase; Humans; Liver; Male; Middle Aged; Prodrugs; Respiratory Tract Infections; Skin Diseases, Infectious; Time Factors

1991
Effect of erythromycin acistrate and erythromycin stearate on human colonic microflora.
    Scandinavian journal of infectious diseases, 1989, Volume: 21, Issue:6

    Topics: Adolescent; Adult; Bacteria, Anaerobic; Colon; Erythromycin; Feces; Gram-Negative Bacteria; Humans; Random Allocation

1989
Erythromycin ethylsuccinate, base and acistrate in the treatment of upper respiratory tract infection: two comparative studies of tolerability.
    The Journal of antimicrobial chemotherapy, 1989, Volume: 24, Issue:3

    Topics: Adolescent; Adult; Aged; Erythromycin; Erythromycin Ethylsuccinate; Female; Gastrointestinal Diseases; Humans; Male; Middle Aged; Respiratory Tract Infections

1989
Efficacy and tolerability of erythromycin acistrate and erythromycin stearate in acute skin infections of patients with atopic eczema.
    The Journal of antimicrobial chemotherapy, 1988, Volume: 21 Suppl D

    Topics: Administration, Cutaneous; Adolescent; Adult; Aged; Dermatitis, Atopic; Double-Blind Method; Erythromycin; Female; Humans; Male; Middle Aged; Ointments; Prodrugs; Random Allocation; Skin Diseases, Infectious; Staphylococcal Skin Infections

1988
Treatment of respiratory tract infections with erythromycin acistrate and two formulations of erythromycin base.
    The Journal of antimicrobial chemotherapy, 1988, Volume: 21 Suppl D

    Topics: Adolescent; Adult; Aged; Double-Blind Method; Erythromycin; Female; Humans; Liver; Male; Middle Aged; Random Allocation; Respiratory Tract Infections; Tablets, Enteric-Coated

1988
Erythromycin acistrate and erythromycin stearate in the treatment of non-gonococcal urethritis.
    The Journal of antimicrobial chemotherapy, 1988, Volume: 21 Suppl D

    Topics: Adolescent; Adult; Chlamydia Infections; Erythromycin; Humans; Male; Prodrugs; Tetracycline; Urethritis

1988
Absorption of erythromycin acistrate and erythromycin base in the fasting and non-fasting state.
    The Journal of antimicrobial chemotherapy, 1988, Volume: 21 Suppl D

    Topics: Adult; Cimetidine; Drug Interactions; Erythromycin; Fasting; Female; Food; Humans; Intestinal Absorption; Male; Random Allocation; Tablets; Tablets, Enteric-Coated

1988
Antibiotic concentration in suction skin blister fluid and saliva after repeated dosage of erythromycin acistrate and erythromycin base.
    The Journal of antimicrobial chemotherapy, 1988, Volume: 21 Suppl D

    Topics: Adult; Blister; Erythromycin; Female; Humans; Hydrolysis; Male; Orosomucoid; Random Allocation; Saliva; Suction

1988
Tonsillar penetration of erythromycin and its 2'-acetyl ester in patients with chronic tonsillitis.
    The Journal of antimicrobial chemotherapy, 1988, Volume: 21 Suppl D

    Topics: Adolescent; Adult; Chronic Disease; Erythromycin; Female; Humans; Hydrolysis; Male; Palatine Tonsil; Premedication; Prodrugs; Random Allocation; Tablets, Enteric-Coated; Tonsillitis

1988
Comparison of erythromycin acistrate and enterocoated erythromycin base in acute respiratory infections.
    The Journal of antimicrobial chemotherapy, 1988, Volume: 21 Suppl D

    Topics: Acute Disease; Adolescent; Adult; Double-Blind Method; Erythromycin; Female; Humans; Liver; Male; Middle Aged; Prodrugs; Random Allocation; Respiratory Tract Infections; Tablets, Enteric-Coated

1988
Erythromycin acistrate and enterocoated pellets of erythromycin base in acute respiratory infections of hospitalized conscripts.
    The Journal of antimicrobial chemotherapy, 1988, Volume: 21 Suppl D

    Topics: Acute Disease; Adolescent; Adult; Erythromycin; Hospitalization; Humans; Liver; Prodrugs; Random Allocation; Respiratory Tract Infections; Streptococcal Infections; Tablets, Enteric-Coated; Virus Diseases

1988
Twice daily dosing of erythromycin acistrate in the treatment of acute bronchitis and pneumonia.
    Arzneimittel-Forschung, 1993, Volume: 43, Issue:9

    Topics: Acute Disease; Adult; Aged; Bronchitis; Double-Blind Method; Doxycycline; Erythromycin; Female; Humans; Male; Middle Aged; Pneumonia, Pneumococcal; Prodrugs; Respiratory Tract Infections

1993

Other Studies

13 other study(ies) available for erythromycin 2'-acetate and erythromycin

ArticleYear
Bioavailability of erythromycin acistrate from hard gelatin capsules containing sodium bicarbonate.
    Pharmaceutical research, 1991, Volume: 8, Issue:8

    Topics: Adult; Bicarbonates; Biological Availability; Capsules; Erythromycin; Female; Humans; Prodrugs; Sodium; Sodium Bicarbonate

1991
Penetration of erythromycin into periapical lesions after repeated doses of erythromycin acistrate and erythromycin stearate: a pilot study.
    Oral surgery, oral medicine, and oral pathology, 1991, Volume: 71, Issue:6

    Topics: Adult; Aged; Biological Availability; Erythromycin; Humans; Middle Aged; Periapical Granuloma; Pilot Projects; Premedication; Prodrugs; Radicular Cyst; Sepsis

1991
Determination of erythromycin base and 2'-acetylerythromycin in human plasma using high-performance liquid chromatography with electrochemical detection.
    Journal of chromatography, 1990, Apr-06, Volume: 526, Issue:2

    Topics: Biological Availability; Chromatography, High Pressure Liquid; Drug Stability; Electrodes; Erythromycin; Humans; Hydrogen-Ion Concentration; Oleandomycin; Oxidation-Reduction; Reproducibility of Results; Temperature

1990
Efficacy of erythromycin acistrate (2'-acetyl erythromycin stearate) and erythromycin stearate in experimental infections in mice.
    The Journal of pharmacology and experimental therapeutics, 1989, Volume: 250, Issue:3

    Topics: Animals; Erythromycin; Mice; Peritonitis; Staphylococcal Infections; Streptococcal Infections; Structure-Activity Relationship

1989
Time course of the antibacterial activity of erythromycin stearate and erythromycin acistrate against two Staphylococcus aureus strains in vitro.
    The Journal of antimicrobial chemotherapy, 1988, Volume: 22, Issue:2

    Topics: Drug Resistance, Microbial; Erythromycin; Prodrugs; Staphylococcus aureus; Time Factors

1988
Concentrations of erythromycin, 2'-acetyl erythromycin, and their anhydro forms in plasma and tonsillar tissue after repeated dosage of erythromycin stearate and erythromycin acistrate.
    Antimicrobial agents and chemotherapy, 1988, Volume: 32, Issue:7

    Topics: Child; Child, Preschool; Dose-Response Relationship, Drug; Drug Administration Schedule; Erythromycin; Female; Humans; Hydrolysis; Male; Palatine Tonsil

1988
Determination of 2'-acetyl erythromycin and erythromycin in human tonsil tissue by HPLC with coulometric detection.
    The Journal of antimicrobial chemotherapy, 1988, Volume: 21 Suppl D

    Topics: Chromatography, High Pressure Liquid; Electrochemistry; Erythromycin; Humans; Palatine Tonsil; Prodrugs

1988
Comparative liver toxicity of various erythromycin derivatives in animals.
    The Journal of antimicrobial chemotherapy, 1988, Volume: 21 Suppl D

    Topics: Animals; Body Weight; Cholangitis; Dogs; Dose-Response Relationship, Drug; Erythromycin; Esters; Female; Liver; Male; Organ Size; Random Allocation; Rats; Rats, Inbred Strains

1988
Erythromycin and 2'-acetyl erythromycin concentrations in plasma and pelvic tissues after repeated doses of erythromycin acistrate.
    Arzneimittel-Forschung, 1993, Volume: 43, Issue:1

    Topics: Biotransformation; Endometrium; Erythromycin; Fallopian Tubes; Female; Humans; Hydrolysis; Middle Aged; Myometrium; Ovary; Pelvis; Prodrugs

1993
Dependence between dissolution rate and porosity of compressed erythromycin acistrate tablets.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 1998, Volume: 46, Issue:2

    Topics: Erythromycin; Kinetics; Microscopy, Electron, Scanning; Molecular Conformation; Molecular Structure; Particle Size; Prodrugs; Solubility; Tablets

1998
The effect of compression force on surface structure, crushing strength, friability and disintegration time of erythromycin acistrate tablets.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 1998, Volume: 46, Issue:3

    Topics: Chemistry, Pharmaceutical; Compressive Strength; Erythromycin; Microscopy, Electron, Scanning; Prodrugs; Surface Properties; Tablets

1998
[Prodrugs].
    Duodecim; laaketieteellinen aikakauskirja, 1997, Volume: 113, Issue:24

    Topics: Acyclovir; Angiotensin-Converting Enzyme Inhibitors; Antiviral Agents; Epinephrine; Erythromycin; Finland; Humans; Penicillins; Prodrugs; Technology, Pharmaceutical; Valacyclovir; Valine

1997
Effect of compression force on the crystal properties of erythromycin acistrate tablets.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2000, Volume: 50, Issue:3

    Topics: Chemistry, Pharmaceutical; Compressive Strength; Crystallization; Erythromycin; Microscopy, Electron, Scanning; Particle Size; Powders; Prodrugs; Tablets; X-Ray Diffraction

2000