Page last updated: 2024-09-05

erlotinib hydrochloride and wortmannin

erlotinib hydrochloride has been researched along with wortmannin in 1 studies

Compound Research Comparison

Studies (erlotinib hydrochloride)	Trials (erlotinib hydrochloride)	Recent Studies (post-2010) (erlotinib hydrochloride)	Studies (wortmannin)	Trials (wortmannin)	Recent Studies (post-2010) (wortmannin)
4,353	786	3,033	4,066	2	726

Protein Interaction Comparison

Protein	Taxonomy	wortmannin (IC50)
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	Homo sapiens (human)	0.0465
Myosin light chain kinase, smooth muscle	Gallus gallus (chicken)	0.26
Metabotropic glutamate receptor 1	Rattus norvegicus (Norway rat)	0.0085
Phosphatidylinositol 3-kinase regulatory subunit alpha	Homo sapiens (human)	0.2368
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	Homo sapiens (human)	0.1309
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	Homo sapiens (human)	0.0493
Serine/threonine-protein kinase mTOR	Homo sapiens (human)	0.04
Phosphatidylinositol 4-kinase alpha	Homo sapiens (human)	0.28
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	Homo sapiens (human)	0.0492
Serine/threonine-protein kinase PLK1	Homo sapiens (human)	0.4433
Myosin light chain kinase, smooth muscle	Homo sapiens (human)	2.3567
Phosphoinositide 3-kinase regulatory subunit 5	Homo sapiens (human)	0.019
Serine/threonine-protein kinase PLK3	Homo sapiens (human)	0.1057
Phosphatidylinositol 4-kinase beta	Homo sapiens (human)	0.44

Research

Studies (1)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	1 (100.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Hedley, DW; Ng, SS; Nicklee, T; Tsao, MS	1

Other Studies

1 other study(ies) available for erlotinib hydrochloride and wortmannin

Article	Year
Effects of the epidermal growth factor receptor inhibitor OSI-774, Tarceva, on downstream signaling pathways and apoptosis in human pancreatic adenocarcinoma. Molecular cancer therapeutics, 2002, Volume: 1, Issue:10 Topics: Adenocarcinoma; Androstadienes; Animals; Antineoplastic Agents; Apoptosis; Deoxycytidine; Enzyme Inhibitors; ErbB Receptors; Erlotinib Hydrochloride; Fluorescent Antibody Technique, Indirect; Gemcitabine; Humans; Image Processing, Computer-Assisted; Immunohistochemistry; In Situ Nick-End Labeling; Male; Mice; Mice, SCID; Microscopy, Fluorescence; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Neoplasm Transplantation; Pancreatic Neoplasms; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Quinazolines; Signal Transduction; Wortmannin	2002

Article

Year

Effects of the epidermal growth factor receptor inhibitor OSI-774, Tarceva, on downstream signaling pathways and apoptosis in human pancreatic adenocarcinoma.

Molecular cancer therapeutics, 2002, Volume: 1, Issue:10

Topics: Adenocarcinoma; Androstadienes; Animals; Antineoplastic Agents; Apoptosis; Deoxycytidine; Enzyme Inhibitors; ErbB Receptors; Erlotinib Hydrochloride; Fluorescent Antibody Technique, Indirect; Gemcitabine; Humans; Image Processing, Computer-Assisted; Immunohistochemistry; In Situ Nick-End Labeling; Male; Mice; Mice, SCID; Microscopy, Fluorescence; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Neoplasm Transplantation; Pancreatic Neoplasms; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Quinazolines; Signal Transduction; Wortmannin

2002