Compounds > erlotinib hydrochloride
Page last updated: 2024-09-05

erlotinib hydrochloride and u 0126

erlotinib hydrochloride has been researched along with u 0126 in 4 studies

Compound Research Comparison

Studies
(erlotinib hydrochloride)		Trials
(erlotinib hydrochloride)		Recent Studies (post-2010)
(erlotinib hydrochloride)		Studies
(u 0126)		Trials
(u 0126)		Recent Studies (post-2010) (u 0126)
4,3537863,0332,81621,213

Protein Interaction Comparison

ProteinTaxonomyerlotinib hydrochloride (IC50)u 0126 (IC50)
RAF proto-oncogene serine/threonine-protein kinaseHomo sapiens (human)0.29
Serine/threonine-protein kinase B-rafHomo sapiens (human)0.25
Amine oxidase [flavin-containing] BRattus norvegicus (Norway rat)0.07
Dual specificity mitogen-activated protein kinase kinase 2Homo sapiens (human)0.2816
Dual specificity mitogen-activated protein kinase kinase 1Homo sapiens (human)0.2529

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chung, WC; Gold, KA; Hittelman, WN; Kang, SM; Ki Hong, W; Kim, ES; Koo, JS; Lee, J; Ryu, SH1
Grandal, MV; Grøvdal, LM; Holst, MR; Kim, J; Knudsen, SL; van Deurs, B1
Deng, ZL; Dong, YC; Han, QL; Jiang, T; Lv, XH; Ren, H; Xing, WJ; Zou, Y1
Macigova, P; Mudry, P; Neradil, J; Noskova, H; Polaskova, K; Slaby, O; Sramek, M; Sterba, J; Veselska, R1

Other Studies

4 other study(ies) available for erlotinib hydrochloride and u 0126

ArticleYear
Prevention of bronchial hyperplasia by EGFR pathway inhibitors in an organotypic culture model.
    Cancer prevention research (Philadelphia, Pa.), 2011, Volume: 4, Issue:8

    Topics: Bronchi; Butadienes; Cell Line, Tumor; Cyclin D1; Enzyme Inhibitors; ErbB Receptors; Erlotinib Hydrochloride; Humans; Hyperplasia; Luciferases; Lung Neoplasms; MAP Kinase Kinase Kinases; Models, Biological; Nitriles; Organ Culture Techniques; Quinazolines; RNA, Small Interfering

2011
EGF receptor inhibitors increase ErbB3 mRNA and protein levels in breast cancer cells.
    Cellular signalling, 2012, Volume: 24, Issue:1

    Topics: Breast Neoplasms; Butadienes; Cell Line, Tumor; Chromones; ErbB Receptors; Erlotinib Hydrochloride; Female; Gefitinib; Gene Expression; Gene Expression Profiling; Humans; Imidazoles; MAP Kinase Kinase 1; Morpholines; Nitriles; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Proto-Oncogene Proteins c-akt; Pyridines; Quinazolines; Receptor, ErbB-2; Receptor, ErbB-3; Receptor, ErbB-4; RNA, Messenger; Signal Transduction; Tyrphostins; Up-Regulation

2012
Effects of epidermal growth factor receptor and phosphatase and tensin homologue gene expression on the inhibition of U87MG glioblastoma cell proliferation induced by protein kinase inhibitors.
    Clinical and experimental pharmacology & physiology, 2013, Volume: 40, Issue:1

    Topics: Butadienes; Cell Line, Tumor; Cell Proliferation; ErbB Receptors; Erlotinib Hydrochloride; Extracellular Signal-Regulated MAP Kinases; Furans; Gene Expression; Glioblastoma; Humans; Nitriles; Phosphatidylinositol 3-Kinases; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Pyridines; Pyrimidines; Quinazolines; Signal Transduction; Sirolimus; TOR Serine-Threonine Kinases

2013
Effects of Sunitinib and Other Kinase Inhibitors on Cells Harboring a
    International journal of molecular sciences, 2018, Sep-01, Volume: 19, Issue:9

    Topics: Butadienes; Cell Line, Tumor; Cell Proliferation; Child; Erlotinib Hydrochloride; Female; Humans; Infant; Male; Mutation; Myofibromatosis; Nitriles; Phosphorylation; Protein Kinase Inhibitors; Pyrazoles; Pyridazines; Receptor, Platelet-Derived Growth Factor beta; Sunitinib

2018