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erlotinib hydrochloride and transforming growth factor beta

erlotinib hydrochloride has been researched along with transforming growth factor beta in 11 studies

Compound Research Comparison

Studies
(erlotinib hydrochloride)
Trials
(erlotinib hydrochloride)
Recent Studies (post-2010)
(erlotinib hydrochloride)
Studies
(transforming growth factor beta)
Trials
(transforming growth factor beta)
Recent Studies (post-2010) (transforming growth factor beta)
4,3537863,03349,11956017,610

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (18.18)29.6817
2010's9 (81.82)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Epstein, D; Haley, JD; Petti, F; Sujka-Kwok, I; Thomson, S1
Dolman, ME; Fretz, MM; Goldschmeding, R; Hennink, WE; Kok, RJ; Lacombe, M; Nguyen, TQ; Pato, J; Prakash, J; Storm, G1
Altorki, N; Camiolo, M; Fenoglio, S; Gao, DC; Johns, C; Kenner, L; Lindsted, T; Mittal, V; Schlederer, M; Sordella, R; Stiles, B; Yao, Z1
Gunn, JR; Korc, M; Sempere, LF1
Al Saleh, S; Khajah, MA; Luqmani, YA; Mathew, PM1
Deitz, S; Gore, J; Korc, M; Ouyang, H1
Ashkenazi, A; Belmont, L; Chan, S; Koeppen, H; Lin, E; McNamara, E; Neve, RM; Pham, T; Settleman, J; Wilson, C; Yauch, RL; Ye, X1
Aoki, N; Celis, E; Harabuchi, Y; Kimura, S; Kobayashi, H; Kumai, T; Oikawa, K1
Abera, MB; Kazanietz, MG1
Bugyik, E; Dezső, K; Mózes, M; Nagy, P; Paku, S; Rókusz, A; Szücs, A; Veres, D1
Black, EP; Collard, JP; Krentz Gober, M; Thompson, K1

Other Studies

11 other study(ies) available for erlotinib hydrochloride and transforming growth factor beta

ArticleYear
Kinase switching in mesenchymal-like non-small cell lung cancer lines contributes to EGFR inhibitor resistance through pathway redundancy.
    Clinical & experimental metastasis, 2008, Volume: 25, Issue:8

    Topics: Benzimidazoles; Carcinoma, Non-Small-Cell Lung; Cell Proliferation; Chromatography, Liquid; Drug Resistance, Neoplasm; ErbB Receptors; Erlotinib Hydrochloride; Humans; Immunoblotting; Lung Neoplasms; Mesoderm; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-akt; Pyrimidines; Quinazolines; Quinolines; Receptor, ErbB-2; Receptor, ErbB-3; Receptors, Fibroblast Growth Factor; Receptors, Platelet-Derived Growth Factor; Respiratory Mucosa; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Spectrometry, Mass, Electrospray Ionization; Thiophenes; Transforming Growth Factor beta; Tumor Cells, Cultured

2008
Intervention in growth factor activated signaling pathways by renally targeted kinase inhibitors.
    Journal of controlled release : official journal of the Controlled Release Society, 2008, Dec-18, Volume: 132, Issue:3

    Topics: Cells, Cultured; Chemistry, Pharmaceutical; Drug Carriers; Endocytosis; Epidermal Growth Factor; ErbB Receptors; Erlotinib Hydrochloride; Fibrosis; Gene Expression Regulation; Humans; Intercellular Signaling Peptides and Proteins; Kidney Tubules, Proximal; Kinetics; Muramidase; Phosphorylation; Protein Kinase Inhibitors; Pyrazoles; Pyrroles; Quinazolines; Receptors, Transforming Growth Factor beta; Signal Transduction; Transforming Growth Factor beta

2008
TGF-beta IL-6 axis mediates selective and adaptive mechanisms of resistance to molecular targeted therapy in lung cancer.
    Proceedings of the National Academy of Sciences of the United States of America, 2010, Aug-31, Volume: 107, Issue:35

    Topics: Animals; Base Sequence; Carcinoma, Non-Small-Cell Lung; Cell Line; Cell Line, Tumor; Cell Movement; Cell Survival; Drug Resistance, Neoplasm; Epithelial Cells; ErbB Receptors; Erlotinib Hydrochloride; Gefitinib; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Interleukin-6; Lung Neoplasms; Mesoderm; Mice; Mice, Nude; Mutation; Protein Kinase Inhibitors; Quinazolines; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Transforming Growth Factor beta

2010
A novel 3-dimensional culture system uncovers growth stimulatory actions by TGFβ in pancreatic cancer cells.
    Cancer biology & therapy, 2011, Aug-01, Volume: 12, Issue:3

    Topics: Animals; Benzamides; Carcinoma, Pancreatic Ductal; Cell Culture Techniques; Cell Line, Tumor; Cell Proliferation; Cisplatin; Culture Media; Deoxycytidine; Dioxoles; Drug Resistance, Neoplasm; Epidermal Growth Factor; ErbB Receptors; Erlotinib Hydrochloride; Extracellular Matrix; Gemcitabine; Humans; Mice; Mice, Transgenic; Pancreatic Neoplasms; Quinazolines; Receptors, Transforming Growth Factor beta; Transforming Growth Factor beta; Transforming Growth Factor beta1; Tumor Microenvironment

2011
Differential effect of growth factors on invasion and proliferation of endocrine resistant breast cancer cells.
    PloS one, 2012, Volume: 7, Issue:7

    Topics: Benzamides; Breast Neoplasms; Cell Movement; Cell Proliferation; Chemokine CCL5; Chromones; Collagenases; Diphenylamine; Epidermal Growth Factor; ErbB Receptors; Erlotinib Hydrochloride; Extracellular Signal-Regulated MAP Kinases; Female; Gene Knockdown Techniques; Humans; Insulin-Like Growth Factor I; Lymphokines; MCF-7 Cells; Morpholines; Phosphorylation; Platelet-Derived Growth Factor; Protein Processing, Post-Translational; Proto-Oncogene Proteins c-akt; Quinazolines; Receptors, Estrogen; RNA, Small Interfering; Transforming Growth Factor beta

2012
microRNA-10b enhances pancreatic cancer cell invasion by suppressing TIP30 expression and promoting EGF and TGF-β actions.
    Oncogene, 2014, Sep-18, Volume: 33, Issue:38

    Topics: Acetyltransferases; Animals; Antineoplastic Agents; Base Sequence; Binding Sites; Carcinoma, Pancreatic Ductal; Cell Line, Tumor; Epidermal Growth Factor; Erlotinib Hydrochloride; Gene Expression; Gene Expression Regulation, Neoplastic; Humans; Kruppel-Like Factor 4; Male; Mice; Mice, Nude; MicroRNAs; Neoplasm Invasiveness; Neoplasm Transplantation; Pancreatic Neoplasms; Quinazolines; RNA Interference; Signal Transduction; Transcription Factors; Transforming Growth Factor beta

2014
AXL inhibition sensitizes mesenchymal cancer cells to antimitotic drugs.
    Cancer research, 2014, Oct-15, Volume: 74, Issue:20

    Topics: Animals; Antineoplastic Agents; Axl Receptor Tyrosine Kinase; CDC2 Protein Kinase; Cisplatin; Cyclin-Dependent Kinases; Docetaxel; Drug Resistance, Neoplasm; Drug Synergism; Epithelial-Mesenchymal Transition; Erlotinib Hydrochloride; HeLa Cells; Humans; Mesoderm; Mice, Nude; Mitosis; Proto-Oncogene Proteins; Quinazolines; Receptor Protein-Tyrosine Kinases; Taxoids; Transforming Growth Factor beta; Xenograft Model Antitumor Assays

2014
Tumor-derived TGF-β and prostaglandin E2 attenuate anti-tumor immune responses in head and neck squamous cell carcinoma treated with EGFR inhibitor.
    Journal of translational medicine, 2014, Sep-21, Volume: 12

    Topics: Carcinoma, Squamous Cell; CD4-Positive T-Lymphocytes; Cell Line, Tumor; Dinoprostone; ErbB Receptors; Erlotinib Hydrochloride; Head and Neck Neoplasms; Humans; Transforming Growth Factor beta

2014
Protein kinase Cα mediates erlotinib resistance in lung cancer cells.
    Molecular pharmacology, 2015, Volume: 87, Issue:5

    Topics: Cell Line, Tumor; Down-Regulation; Drug Resistance, Neoplasm; Epithelial-Mesenchymal Transition; ErbB Receptors; Erlotinib Hydrochloride; Humans; Lung Neoplasms; Mutation; Protein Kinase C-alpha; Protein Kinase Inhibitors; Quinazolines; Signal Transduction; Transforming Growth Factor beta; Up-Regulation

2015
Ductular reaction correlates with fibrogenesis but does not contribute to liver regeneration in experimental fibrosis models.
    PloS one, 2017, Volume: 12, Issue:4

    Topics: Animals; Carbon Tetrachloride; Cell Proliferation; Disease Models, Animal; Erlotinib Hydrochloride; Fibrosis; Imatinib Mesylate; Keratin-19; Liver; Liver Cirrhosis; Liver Regeneration; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microscopy, Confocal; Protein Kinase Inhibitors; Thioacetamide; Transforming Growth Factor beta

2017
A microRNA signature of response to erlotinib is descriptive of TGFβ behaviour in NSCLC.
    Scientific reports, 2017, 06-23, Volume: 7, Issue:1

    Topics: Carcinoma, Non-Small-Cell Lung; Cell Cycle; Cell Line, Tumor; Drug Resistance, Neoplasm; Enzyme Activation; Epithelial-Mesenchymal Transition; Erlotinib Hydrochloride; Extracellular Signal-Regulated MAP Kinases; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; MicroRNAs; Phenotype; Promoter Regions, Genetic; Protein Binding; Proto-Oncogene Proteins c-akt; Smad Proteins; Time Factors; Transforming Growth Factor beta

2017