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erlotinib hydrochloride and transforming growth factor alpha

erlotinib hydrochloride has been researched along with transforming growth factor alpha in 17 studies

Compound Research Comparison

Studies (erlotinib hydrochloride)	Trials (erlotinib hydrochloride)	Recent Studies (post-2010) (erlotinib hydrochloride)	Studies (transforming growth factor alpha)	Trials (transforming growth factor alpha)	Recent Studies (post-2010) (transforming growth factor alpha)
4,353	786	3,033	4,301	44	623

Research

Studies (17)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	10 (58.82)	29.6817
2010's	7 (41.18)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Faj, D; Kurbel, S	1
Arteaga, CL; Carpenter, G; Gazdar, AF; Muthuswamy, SK; Narasanna, A; Perez-Torres, M; Wang, SE; Wu, FY; Xiang, B; Yang, S	1
Desbois-Mouthon, C; Fartoux, L; Poupon, R; Rosmorduc, O	1
Alvarez-Hernandez, D; Arcidiacono, MV; Cannata-Andia, J; Dusso, AS; Gonzalez-Suarez, I; Lu, Y; Sato, T; Slatopolsky, E; Tokumoto, M; Tominaga, Y; Yang, J	1
Davidson, C; Hardie, WD; Ikegami, M; Korfhagen, TR; Le Cras, TD; Leikauf, GD; Prestridge, A; Whitsett, JA	1
Holtkamp, N; Malzer, E; Mautner, VF; Mawrin, C; Mucha, J; Okuducu, AF; Schildhaus, HU; von Deimling, A; Zietsch, J	1
Blair, E; Clark, JI; Cohen, EE; Dancey, JE; Davis, DW; Dekker, A; Karrison, TG; Kozloff, MF; Liu, W; Nattam, S; Pierce, C; Seiwert, TY; Stenson, K; Vokes, EE; Wong, SJ; Yan, DH	1
Davidson, CR; Hardie, WD; Ikegami, M; Korfhagen, TR; Le Cras, TD; Schmidt, SM; Whitsett, JA	1
España, A; López-Picazo, JM; López-Zabalza, MJ; Marquina, M; Pelacho, B; Pretel, M	1
Ren, S; Tang, L; Yan, L; Zhang, J; Zhang, L; Zhou, C; Zhou, S	1
Addison, CL; Bradbury, PA; Ding, K; Goss, GD; Le Maître, A; Seymour, L; Shepherd, FA; Tsao, MS; Zhao, H	1
Argiris, A; Ferris, RL; Freilino, ML; Gooding, WE; Grandis, JR; Gross, N; Moskowitz, HS; Thomas, SM	1
Batlle, D; Egido, J; Eguchi, S; Keri, G; Morgado-Pascual, JL; Ortiz, A; Pato, J; Ramos, AM; Rayego-Mateos, S; Ruiz-Ortega, M; Sanz, AB	1
Ahuja, A; Chan, AT; Chan, C; Chan, SL; Dattatray, RD; Ho, WM; Hui, EP; King, AD; Lau, W; Ma, BB; Mo, F; Poon, A; To, KF; Wong, SC	1
Arcidiacono, MV; Dusso, A; Fernandez, E; Yang, J	1
Acker, T; Acker-Palmer, A; Cuesta, AM; Dopeso, H; Garvalov, BK; Henze, AT; Jiao, HK; Jurida, L; Kracht, M	1
Chung, S; Fan, X; Harris, RC; Li, Y; Li, Z; Niu, A; Overstreet, JM; Wang, S; Wang, Y; Zhang, MZ	1

Reviews

1 review(s) available for erlotinib hydrochloride and transforming growth factor alpha

Article	Year
[Anti-EGFR therapy: towards a "à la carte" targeting of hepatocellular carcinoma]. Gastroenterologie clinique et biologique, 2006, Volume: 30, Issue:10 Topics: Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Line, Tumor; Cetuximab; Clinical Trials, Phase II as Topic; Disease Models, Animal; Epidermal Growth Factor; ErbB Receptors; Erlotinib Hydrochloride; Gefitinib; Humans; Ligands; Liver Neoplasms; Multicenter Studies as Topic; Neoplasm Recurrence, Local; Protein Kinase Inhibitors; Quinazolines; Rats; Signal Transduction; Transforming Growth Factor alpha	2006

Article

Year

[Anti-EGFR therapy: towards a "à la carte" targeting of hepatocellular carcinoma].

Gastroenterologie clinique et biologique, 2006, Volume: 30, Issue:10

Topics: Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Line, Tumor; Cetuximab; Clinical Trials, Phase II as Topic; Disease Models, Animal; Epidermal Growth Factor; ErbB Receptors; Erlotinib Hydrochloride; Gefitinib; Humans; Ligands; Liver Neoplasms; Multicenter Studies as Topic; Neoplasm Recurrence, Local; Protein Kinase Inhibitors; Quinazolines; Rats; Signal Transduction; Transforming Growth Factor alpha

2006

Trials

4 trial(s) available for erlotinib hydrochloride and transforming growth factor alpha

Article	Year
Erlotinib and bevacizumab in patients with recurrent or metastatic squamous-cell carcinoma of the head and neck: a phase I/II study. The Lancet. Oncology, 2009, Volume: 10, Issue:3 Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Carcinoma, Squamous Cell; ErbB Receptors; Erlotinib Hydrochloride; Female; Head and Neck Neoplasms; Humans; Male; Middle Aged; Multivariate Analysis; Quinazolines; Regression Analysis; Transforming Growth Factor alpha; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-2	2009
Clinical efficacy of erlotinib in patients previously treated for advanced non-small cell lung cancer. Respirology (Carlton, Vic.), 2009, Volume: 14, Issue:5 Topics: Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; Carcinoma, Non-Small-Cell Lung; Disease Progression; Erlotinib Hydrochloride; Female; Follow-Up Studies; Humans; Lung Neoplasms; Male; Middle Aged; Predictive Value of Tests; Protein Kinase Inhibitors; Quinazolines; Retrospective Studies; Survival Rate; Transforming Growth Factor alpha; Treatment Outcome; Vascular Endothelial Growth Factor A	2009
Serum biomarker modulation following molecular targeting of epidermal growth factor and cyclooxygenase pathways: a pilot randomized trial in head and neck cancer. Oral oncology, 2012, Volume: 48, Issue:11 Topics: Adult; Aged; Antineoplastic Agents; Biomarkers, Tumor; Carcinoma, Squamous Cell; Double-Blind Method; Enzyme-Linked Immunosorbent Assay; ErbB Receptors; Erlotinib Hydrochloride; Female; Head and Neck Neoplasms; Hepatocyte Growth Factor; Humans; Interleukin-6; Male; Middle Aged; Neoadjuvant Therapy; Pilot Projects; Placebos; Prospective Studies; Protein Kinase Inhibitors; Quinazolines; Sulindac; Transforming Growth Factor alpha	2012
Intermittent versus continuous erlotinib with concomitant modified "XELOX" (q3W) in first-line treatment of metastatic colorectal cancer: correlation with serum amphiregulin and transforming growth factor alpha. Cancer, 2013, Dec-01, Volume: 119, Issue:23 Topics: Adult; Aged; Amphiregulin; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Colorectal Neoplasms; Deoxycytidine; Drug Administration Schedule; EGF Family of Proteins; Erlotinib Hydrochloride; Female; Fluorouracil; Glycoproteins; Humans; Intercellular Signaling Peptides and Proteins; Male; Middle Aged; Mutation; Neoplasm Metastasis; Oxaloacetates; Patient Compliance; Prognosis; Protein Kinase Inhibitors; Proto-Oncogene Proteins; Proto-Oncogene Proteins p21(ras); Quinazolines; ras Proteins; Transforming Growth Factor alpha	2013

Other Studies

12 other study(ies) available for erlotinib hydrochloride and transforming growth factor alpha

Article	Year
Association of skin rash and tumor response to HER1/EGFR inhibition: does HER1 stimulated tumor growth depend on circulatory instead of paracrine ligands? Medical hypotheses, 2005, Volume: 64, Issue:6 Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Autocrine Communication; Cetuximab; Epidermal Growth Factor; ErbB Receptors; Erlotinib Hydrochloride; Exanthema; Humans; Ligands; Models, Biological; Neoplasm Proteins; Neoplasms; Paracrine Communication; Quinazolines; Skin; Transforming Growth Factor alpha; Treatment Outcome	2005
HER2 kinase domain mutation results in constitutive phosphorylation and activation of HER2 and EGFR and resistance to EGFR tyrosine kinase inhibitors. Cancer cell, 2006, Volume: 10, Issue:1 Topics: Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Apoptosis; Cell Line, Tumor; Cell Movement; Cell Proliferation; Drug Resistance, Neoplasm; Epidermal Growth Factor; ErbB Receptors; Erlotinib Hydrochloride; Female; Gefitinib; Humans; Mice; Mice, Nude; Models, Biological; Morpholines; Mutation; Phosphorylation; Protein Kinase Inhibitors; Quinazolines; Receptor, ErbB-2; RNA, Small Interfering; Transforming Growth Factor alpha; Trastuzumab; Xenograft Model Antitumor Assays	2006
EGFR activation increases parathyroid hyperplasia and calcitriol resistance in kidney disease. Journal of the American Society of Nephrology : JASN, 2008, Volume: 19, Issue:2 Topics: Animals; Calcitriol; Carcinoma, Squamous Cell; CCAAT-Enhancer-Binding Protein-beta; Cell Line, Tumor; Disease Models, Animal; Drug Resistance; ErbB Receptors; Erlotinib Hydrochloride; Female; Genes, Reporter; Humans; Hyperparathyroidism, Secondary; Hyperplasia; Protein Kinase Inhibitors; Quinazolines; Rats; Rats, Sprague-Dawley; Receptors, Calcitriol; Renal Insufficiency, Chronic; Transforming Growth Factor alpha	2008
EGF receptor tyrosine kinase inhibitors diminish transforming growth factor-alpha-induced pulmonary fibrosis. American journal of physiology. Lung cellular and molecular physiology, 2008, Volume: 294, Issue:6 Topics: Animals; Bronchoalveolar Lavage Fluid; Doxycycline; ErbB Receptors; Erlotinib Hydrochloride; Gefitinib; Gene Expression; Humans; Mice; Pulmonary Fibrosis; Quinazolines; RNA, Messenger; Transforming Growth Factor alpha	2008
EGFR and erbB2 in malignant peripheral nerve sheath tumors and implications for targeted therapy. Neuro-oncology, 2008, Volume: 10, Issue:6 Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Blotting, Western; Cell Line, Tumor; Cell Proliferation; Drug Delivery Systems; Drug Synergism; Epidermal Growth Factor; ErbB Receptors; Erlotinib Hydrochloride; Gene Dosage; Genes, p16; Genes, p53; Humans; Immunohistochemistry; Nerve Sheath Neoplasms; Polymorphism, Single-Stranded Conformational; PTEN Phosphohydrolase; Quinazolines; Receptor, ErbB-2; Reverse Transcriptase Polymerase Chain Reaction; Transforming Growth Factor alpha; Trastuzumab	2008
Rapamycin prevents transforming growth factor-alpha-induced pulmonary fibrosis. American journal of respiratory cell and molecular biology, 2009, Volume: 41, Issue:5 Topics: Animals; Carrier Proteins; Collagen; Disease Models, Animal; Disease Progression; Doxycycline; Enzyme Inhibitors; ErbB Receptors; Erlotinib Hydrochloride; Gene Expression Regulation; Humans; Lung; Mice; Mice, Transgenic; Phosphatidylinositol 3-Kinases; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Proliferating Cell Nuclear Antigen; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Pulmonary Fibrosis; Quinazolines; Respiratory Mechanics; Ribosomal Protein S6 Kinases, 70-kDa; Signal Transduction; Sirolimus; Time Factors; TOR Serine-Threonine Kinases; Transforming Growth Factor alpha; Uteroglobin	2009
An imbalance in Akt/mTOR is involved in the apoptotic and acantholytic processes in a mouse model of pemphigus vulgaris. Experimental dermatology, 2009, Volume: 18, Issue:9 Topics: Acantholysis; Animals; Apoptosis; Betacellulin; Carrier Proteins; Disease Models, Animal; Enzyme Activation; Epidermal Growth Factor; Epidermis; ErbB Receptors; Erlotinib Hydrochloride; Humans; Immunoglobulin G; Intercellular Signaling Peptides and Proteins; Intradermal Tests; Isoenzymes; Mice; Mice, Inbred C57BL; Pemphigus; Phosphotransferases (Alcohol Group Acceptor); Proto-Oncogene Proteins c-akt; Pyrazoles; Pyrimidines; Quinazolines; Sirolimus; src-Family Kinases; TOR Serine-Threonine Kinases; Transforming Growth Factor alpha	2009
Plasma transforming growth factor alpha and amphiregulin protein levels in NCIC Clinical Trials Group BR.21. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2010, Dec-20, Volume: 28, Issue:36 Topics: Amphiregulin; Antineoplastic Agents; Biomarkers, Tumor; Carcinoma, Non-Small-Cell Lung; EGF Family of Proteins; Erlotinib Hydrochloride; Female; Glycoproteins; Humans; Intercellular Signaling Peptides and Proteins; Lung Neoplasms; Male; Middle Aged; Prognosis; Quinazolines; Retrospective Studies; Transforming Growth Factor alpha	2010
TWEAK transactivation of the epidermal growth factor receptor mediates renal inflammation. The Journal of pathology, 2013, Volume: 231, Issue:4 Topics: ADAM Proteins; ADAM17 Protein; Animals; Cells, Cultured; Cytokine TWEAK; Epithelial Cells; ErbB Receptors; Erlotinib Hydrochloride; Female; Gene Silencing; Heparin-binding EGF-like Growth Factor; Humans; Inflammation Mediators; Intercellular Signaling Peptides and Proteins; Kidney Tubules; Ligands; Mice; Mice, Inbred C57BL; Nephritis; NF-kappa B; Phosphorylation; Quinazolines; Receptors, Tumor Necrosis Factor; Signal Transduction; Transcriptional Activation; Transforming Growth Factor alpha; Tumor Necrosis Factors; TWEAK Receptor	2013
The induction of C/EBPβ contributes to vitamin D inhibition of ADAM17 expression and parathyroid hyperplasia in kidney disease. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2015, Volume: 30, Issue:3 Topics: ADAM Proteins; ADAM17 Protein; Animals; Antineoplastic Agents; Apoptosis; Blotting, Western; Calcitriol; CCAAT-Enhancer-Binding Protein-beta; Cell Proliferation; Cells, Cultured; ErbB Receptors; Erlotinib Hydrochloride; Gene Expression Regulation; Humans; Hyperparathyroidism, Secondary; Hyperplasia; Immunoenzyme Techniques; Kidney Diseases; Parathyroid Glands; Parathyroid Hormone; Rats; Real-Time Polymerase Chain Reaction; Receptors, Calcitriol; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Transforming Growth Factor alpha; Vitamin D; Vitamins	2015
PHD3 Controls Lung Cancer Metastasis and Resistance to EGFR Inhibitors through TGFα. Cancer research, 2018, 04-01, Volume: 78, Issue:7 Topics: A549 Cells; Animals; Antineoplastic Agents; Apoptosis Regulatory Proteins; Cell Hypoxia; Cell Line, Tumor; Drug Resistance, Neoplasm; Epithelial-Mesenchymal Transition; ErbB Receptors; Erlotinib Hydrochloride; Female; HCT116 Cells; Humans; Hypoxia-Inducible Factor-Proline Dioxygenases; Intracellular Signaling Peptides and Proteins; Lung Neoplasms; Mice; Mice, Nude; Mitochondrial Proteins; Neoplasm Metastasis; Protein Kinase Inhibitors; Transforming Growth Factor alpha; Tumor Microenvironment; Xenograft Model Antitumor Assays	2018
Inhibition of Epidermal Growth Factor Receptor Activation Is Associated With Improved Diabetic Nephropathy and Insulin Resistance in Type 2 Diabetes. Diabetes, 2018, Volume: 67, Issue:9 Topics: Albuminuria; Animals; Biomarkers; Crosses, Genetic; Cytokines; Diabetes Mellitus, Type 2; Diabetic Nephropathies; ErbB Receptors; Erlotinib Hydrochloride; Fibrosis; Glomerulonephritis; Hypoglycemic Agents; Insulin Resistance; Kidney; Macrophages; Membrane Transport Modulators; Mice, Knockout; Mice, Mutant Strains; Nitric Oxide Synthase Type III; Oxidative Stress; Protein Kinase Inhibitors; T-Lymphocytes; Transforming Growth Factor alpha	2018