Page last updated: 2024-09-05

erlotinib hydrochloride and sertraline

erlotinib hydrochloride has been researched along with sertraline in 1 studies

Compound Research Comparison

Studies
(erlotinib hydrochloride)
Trials
(erlotinib hydrochloride)
Recent Studies (post-2010)
(erlotinib hydrochloride)
Studies
(sertraline)
Trials
(sertraline)
Recent Studies (post-2010) (sertraline)
4,3537863,0333,4801,0281,329

Protein Interaction Comparison

ProteinTaxonomyerlotinib hydrochloride (IC50)sertraline (IC50)
5-hydroxytryptamine receptor 4Cavia porcellus (domestic guinea pig)1.083
Aldo-keto reductase family 1 member B1Rattus norvegicus (Norway rat)0.9848
Muscarinic acetylcholine receptor M2Homo sapiens (human)2.7675
Muscarinic acetylcholine receptor M4Homo sapiens (human)2.6309
Cytochrome P450 3A4Homo sapiens (human)0.8
Muscarinic acetylcholine receptor M5Homo sapiens (human)0.5073
Alpha-2A adrenergic receptorHomo sapiens (human)0.2888
Cytochrome P450 2D6Homo sapiens (human)1.4
Muscarinic acetylcholine receptor M1Homo sapiens (human)1.2882
Angiotensin-converting enzymeOryctolagus cuniculus (rabbit)8.3173
Alpha-2B adrenergic receptorHomo sapiens (human)0.1814
Alpha-2C adrenergic receptorHomo sapiens (human)4.477
DRattus norvegicus (Norway rat)0.26
D(3) dopamine receptorRattus norvegicus (Norway rat)0.26
Sodium-dependent noradrenaline transporter Homo sapiens (human)0.8783
Sodium-dependent dopamine transporterRattus norvegicus (Norway rat)0.825
D(1B) dopamine receptorRattus norvegicus (Norway rat)0.26
5-hydroxytryptamine receptor 2AHomo sapiens (human)2.7409
5-hydroxytryptamine receptor 2CHomo sapiens (human)1.083
D(4) dopamine receptorRattus norvegicus (Norway rat)0.26
3-oxo-5-alpha-steroid 4-dehydrogenase 2Homo sapiens (human)0.8
Sodium-dependent serotonin transporterHomo sapiens (human)0.0016
Sodium-dependent serotonin transporterRattus norvegicus (Norway rat)0.1743
Melanocortin receptor 5Homo sapiens (human)4.598
Cytochrome P450 2C19Homo sapiens (human)0.655
5-hydroxytryptamine receptor 2BHomo sapiens (human)3.3935
D(2) dopamine receptorRattus norvegicus (Norway rat)0.26
Sodium-dependent dopamine transporter Homo sapiens (human)0.2175
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)8.3173
Nuclear receptor subfamily 3 group C member 3 Bos taurus (cattle)8.3173
Sigma non-opioid intracellular receptor 1Homo sapiens (human)0.0697
TransporterRattus norvegicus (Norway rat)0.26

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cheng, F; Jiang, X; Liu, M; Lu, W; Lv, J; Pang, X; Shen, X; Wang, Q; Zhao, Z1

Other Studies

1 other study(ies) available for erlotinib hydrochloride and sertraline

ArticleYear
Repurposing sertraline sensitizes non-small cell lung cancer cells to erlotinib by inducing autophagy.
    JCI insight, 2018, 06-07, Volume: 3, Issue:11

    Topics: Adenylate Kinase; Animals; Antineoplastic Combined Chemotherapy Protocols; Autophagy; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Survival; Drug Repositioning; Drug Resistance, Neoplasm; Drug Synergism; Erlotinib Hydrochloride; Humans; Lung Neoplasms; Male; Mice; Sertraline; Signal Transduction; Survival Analysis; TOR Serine-Threonine Kinases; Xenograft Model Antitumor Assays

2018