Page last updated: 2024-09-05

erlotinib hydrochloride and s 1033

erlotinib hydrochloride has been researched along with s 1033 in 11 studies

Compound Research Comparison

Studies
(erlotinib hydrochloride)
Trials
(erlotinib hydrochloride)
Recent Studies (post-2010)
(erlotinib hydrochloride)
Studies
(s 1033)
Trials
(s 1033)
Recent Studies (post-2010) (s 1033)
4,3537863,0331,4071471,074

Protein Interaction Comparison

ProteinTaxonomyerlotinib hydrochloride (IC50)s 1033 (IC50)
Voltage-dependent L-type calcium channel subunit alpha-1FHomo sapiens (human)4.7
Solute carrier family 22 member 3Homo sapiens (human)0.5
Tyrosine-protein kinase ABL1Homo sapiens (human)0.34
Low-density lipoprotein receptorHomo sapiens (human)9.8
FibronectinHomo sapiens (human)0.12
RAF proto-oncogene serine/threonine-protein kinaseHomo sapiens (human)1.1
Tyrosine-protein kinase LckHomo sapiens (human)0.1082
Macrophage colony-stimulating factor 1 receptorHomo sapiens (human)0.677
Tyrosine-protein kinase LynHomo sapiens (human)1.281
Cytochrome P450 3A4Homo sapiens (human)0.58
Macrophage colony-stimulating factor 1 receptorMus musculus (house mouse)0.534
Platelet-derived growth factor receptor betaHomo sapiens (human)0.052
Mast/stem cell growth factor receptor KitHomo sapiens (human)0.1115
Breakpoint cluster region proteinHomo sapiens (human)0.0575
Proto-oncogene tyrosine-protein kinase SrcHomo sapiens (human)1.01
Solute carrier family 2, facilitated glucose transporter member 4Mus musculus (house mouse)0.042
Ribosyldihydronicotinamide dehydrogenase [quinone]Homo sapiens (human)1.0905
Platelet-derived growth factor receptor alphaHomo sapiens (human)0.0368
Ephrin type-A receptor 2Homo sapiens (human)0.033
Receptor-type tyrosine-protein kinase FLT3Homo sapiens (human)9.548
Voltage-dependent L-type calcium channel subunit alpha-1D Homo sapiens (human)4.7
Epithelial discoidin domain-containing receptor 1Homo sapiens (human)0.0371
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)0.2879
Voltage-dependent L-type calcium channel subunit alpha-1SHomo sapiens (human)4.7
Voltage-dependent L-type calcium channel subunit alpha-1CHomo sapiens (human)4.7
Discoidin domain-containing receptor 2Homo sapiens (human)0.0289
Proprotein convertase subtilisin/kexin type 9Homo sapiens (human)9.8
Broad substrate specificity ATP-binding cassette transporter ABCG2Homo sapiens (human)2.5

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (9.09)29.6817
2010's8 (72.73)24.3611
2020's2 (18.18)2.80

Authors

AuthorsStudies
Gelderblom, H; Guchelaar, HJ; van Erp, NP1
Geoerger, B; Leblond, P1
Beijnen, JH; Harmsen, S; Maas-Bakker, RF; Meijerman, I; Schellens, JH1
Andriamanana, I; Duretz, B; Gana, I; Hulin, A1
Bacus, S; Brown, AM; Doherty, KR; Kramer, JW; Moran, DM; Shell, SA; Talbert, DR; Trusk, PB; Wappel, RL1
Ashby, CR; Chen, ZS; Kathawala, RJ; Wang, YJ1
Ding, JF; Zhong, DF1
Broutin, S; Gil, S; Jovelet, C; Mir, O; Paci, A1
Aderhold, C; Birk, R; Hock, C; Hörmann, K; Kramer, B; Kuhlin, B; Lammert, A; Schultz, JD1
Brors, B; Haibe-Kains, B; Kurilov, R1
Aderhold, C; Birk, R; Huber, L; Kramer, B; Mueller, CE; Rotter, N; Schell, A1

Reviews

5 review(s) available for erlotinib hydrochloride and s 1033

ArticleYear
Clinical pharmacokinetics of tyrosine kinase inhibitors.
    Cancer treatment reviews, 2009, Volume: 35, Issue:8

    Topics: Administration, Oral; Antineoplastic Agents; Benzamides; Benzenesulfonates; Biological Availability; Cytochrome P-450 Enzyme System; Dasatinib; Drug Interactions; Erlotinib Hydrochloride; Gefitinib; Humans; Imatinib Mesylate; Indoles; Intestinal Absorption; Lapatinib; Niacinamide; Phenylurea Compounds; Piperazines; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Pyridines; Pyrimidines; Pyrroles; Quinazolines; Sorafenib; Sunitinib; Thiazoles; Tissue Distribution

2009
[Indications and current development of new targeted therapies in pediatric oncology].
    Bulletin du cancer, 2011, Volume: 98, Issue:5

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Benzamides; Benzenesulfonates; Bevacizumab; Child; Dasatinib; Erlotinib Hydrochloride; Hedgehog Proteins; Humans; Imatinib Mesylate; Indoles; Integrins; Molecular Targeted Therapy; Neoplasms; Niacinamide; Nifurtimox; Phenylurea Compounds; Piperazines; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Pyridines; Pyrimidines; Pyrroles; Quinazolines; Sorafenib; Sunitinib; Thiazoles; TOR Serine-Threonine Kinases

2011
Recent advances regarding the role of ABC subfamily C member 10 (ABCC10) in the efflux of antitumor drugs.
    Chinese journal of cancer, 2014, Volume: 33, Issue:5

    Topics: Antineoplastic Agents; Benzamides; Benzylisoquinolines; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Erlotinib Hydrochloride; Humans; Imatinib Mesylate; Imidazoles; Lapatinib; Multidrug Resistance-Associated Proteins; Piperazines; Purines; Pyrimidines; Quinazolines; Sildenafil Citrate; Sulfonamides; Sulfones; Taxoids; Triazines; Vardenafil Dihydrochloride

2014
[Clinical pharmacokinetics of small molecule tyrosine kinase inhibitors].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2013, Volume: 48, Issue:7

    Topics: Antineoplastic Agents; Crown Ethers; Cytochrome P-450 Enzyme System; Dasatinib; Drug Interactions; Erlotinib Hydrochloride; Gefitinib; Glucuronosyltransferase; Humans; Imatinib Mesylate; Indoles; Niacinamide; Phenylurea Compounds; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Pyrimidines; Pyrroles; Quinazolines; Sorafenib; Sunitinib

2013
[Tyrosine kinase inhibitors and pregnancy: A risk to the fetus?].
    Bulletin du cancer, 2016, Volume: 103, Issue:5

    Topics: Abnormalities, Drug-Induced; Adult; Antineoplastic Agents; Dasatinib; Erlotinib Hydrochloride; Female; Fetus; Gefitinib; Humans; Imatinib Mesylate; Lapatinib; Maternal Age; Placenta; Pregnancy; Pregnancy Complications, Neoplastic; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Pyrimidines; Quinazolines; Risk

2016

Other Studies

6 other study(ies) available for erlotinib hydrochloride and s 1033

ArticleYear
PXR-mediated P-glycoprotein induction by small molecule tyrosine kinase inhibitors.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2013, Mar-12, Volume: 48, Issue:4-5

    Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line, Tumor; Drug Resistance, Neoplasm; Erlotinib Hydrochloride; Gefitinib; Humans; Niacinamide; Phenylurea Compounds; Piperidines; Pregnane X Receptor; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Pyrimidines; Quinazolines; Receptors, Steroid; Sorafenib

2013
Simultaneous analysis of anticancer agents bortezomib, imatinib, nilotinib, dasatinib, erlotinib, lapatinib, sorafenib, sunitinib and vandetanib in human plasma using LC/MS/MS.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2013, May-01, Volume: 926

    Topics: Antineoplastic Agents; Benzamides; Boronic Acids; Bortezomib; Chromatography, Liquid; Dasatinib; Erlotinib Hydrochloride; Humans; Imatinib Mesylate; Indoles; Lapatinib; Niacinamide; Phenylurea Compounds; Piperazines; Piperidines; Pyrazines; Pyrimidines; Pyrroles; Quinazolines; Reproducibility of Results; Sorafenib; Sunitinib; Tandem Mass Spectrometry; Thiazoles

2013
Multi-parameter in vitro toxicity testing of crizotinib, sunitinib, erlotinib, and nilotinib in human cardiomyocytes.
    Toxicology and applied pharmacology, 2013, Oct-01, Volume: 272, Issue:1

    Topics: Caspase 3; Caspase 7; Cell Survival; Cells, Cultured; Cholesterol; Crizotinib; Enzyme Activation; ERG1 Potassium Channel; Erlotinib Hydrochloride; Ether-A-Go-Go Potassium Channels; Humans; Indoles; Ion Channels; Lipids; Myocytes, Cardiac; Patch-Clamp Techniques; Pluripotent Stem Cells; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Pyrazoles; Pyridines; Pyrimidines; Pyrroles; Quinazolines; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction; RNA; Sunitinib

2013
Impact of Small Molecules on β-Catenin and E-Cadherin Expression in HPV16-positive and -negative Squamous Cell Carcinomas.
    Anticancer research, 2017, Volume: 37, Issue:6

    Topics: Antigens, CD; Antineoplastic Agents; beta Catenin; Cadherins; Carcinoma, Squamous Cell; Cell Line, Tumor; Dasatinib; Erlotinib Hydrochloride; Gefitinib; Head and Neck Neoplasms; Human papillomavirus 16; Humans; Protein Kinase Inhibitors; Pyrimidines; Quinazolines

2017
Assessment of modelling strategies for drug response prediction in cell lines and xenografts.
    Scientific reports, 2020, 02-18, Volume: 10, Issue:1

    Topics: Animals; Biomarkers, Pharmacological; Cell Line, Tumor; Erlotinib Hydrochloride; Humans; Imidazoles; Indoles; Lapatinib; Machine Learning; Mice; Neoplasms; Organ Specificity; Paclitaxel; Piperazines; Prognosis; Pyrimidines; Sorafenib; Sulfonamides; Xenograft Model Antitumor Assays

2020
Tyrosine Kinase Inhibitors and Everolimus Reduce IGF1R Expression in HPV16-positive and -negative Squamous Cell Carcinoma.
    Anticancer research, 2020, Volume: 40, Issue:7

    Topics: Antineoplastic Agents; Cell Line, Tumor; Dasatinib; Erlotinib Hydrochloride; Everolimus; Gefitinib; Head and Neck Neoplasms; Human papillomavirus 16; Humans; Papillomavirus Infections; Protein Kinase Inhibitors; Pyrimidines; Receptor, IGF Type 1; Squamous Cell Carcinoma of Head and Neck

2020