Protein | Taxonomy | erlotinib hydrochloride (IC50) | resveratrol (IC50) |
Chain A, Leukotriene A-4 hydrolase | Homo sapiens (human) | | 212 |
Chain A, Leukotriene A-4 hydrolase | Homo sapiens (human) | | 212 |
Chain A, Leukotriene A-4 hydrolase | Homo sapiens (human) | | 212 |
Chain A, Leukotriene A-4 hydrolase | Homo sapiens (human) | | 212 |
Chain A, Leukotriene A-4 hydrolase | Homo sapiens (human) | | 212 |
Chain A, Leukotriene A-4 hydrolase | Homo sapiens (human) | | 212 |
Chain A, Leukotriene A-4 hydrolase | Homo sapiens (human) | | 212 |
Chain A, Leukotriene A-4 hydrolase | Homo sapiens (human) | | 212 |
Chain A, Leukotriene A-4 hydrolase | Homo sapiens (human) | | 212 |
Chain A, Leukotriene A-4 hydrolase | Homo sapiens (human) | | 212 |
Chain A, Leukotriene A-4 hydrolase | Homo sapiens (human) | | 212 |
Chain A, Leukotriene A-4 hydrolase | Homo sapiens (human) | | 212 |
Chain A, Leukotriene A-4 hydrolase | Homo sapiens (human) | | 212 |
Chain A, Leukotriene A-4 hydrolase | Homo sapiens (human) | | 212 |
Chain A, Leukotriene A-4 hydrolase | Homo sapiens (human) | | 212 |
Chain A, Leukotriene A-4 hydrolase | Homo sapiens (human) | | 212 |
Chain A, Leukotriene A-4 hydrolase | Homo sapiens (human) | | 212 |
M18 aspartyl aminopeptidase | Plasmodium falciparum 3D7 | | 2.242 |
Vif | Human immunodeficiency virus 1 | | 25.31 |
DNA dC->dU-editing enzyme APOBEC-3G isoform 1 | Homo sapiens (human) | | 25.31 |
Transient receptor potential cation channel subfamily A member 1 | Homo sapiens (human) | | 0.75 |
Amyloid-beta precursor protein | Homo sapiens (human) | | 2.6 |
Cytochrome P450 1A2 | Homo sapiens (human) | | 3 |
Prostaglandin G/H synthase 1 | Ovis aries (sheep) | | 2.025 |
Aldo-keto reductase family 1 member B1 | Rattus norvegicus (Norway rat) | | 2.312 |
Luciferin 4-monooxygenase | Photinus pyralis (common eastern firefly) | | 0.0589 |
Cytochrome P450 3A4 | Homo sapiens (human) | | 0.6 |
Neuronal acetylcholine receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | | 0.685 |
DNA polymerase alpha catalytic subunit | Homo sapiens (human) | | 3.3 |
Polyunsaturated fatty acid 5-lipoxygenase | Homo sapiens (human) | | 4.9 |
Aromatase | Homo sapiens (human) | | 0.96 |
Cytochrome P450 2C9 | Homo sapiens (human) | | 7 |
Neuronal acetylcholine receptor subunit beta-2 | Rattus norvegicus (Norway rat) | | 0.685 |
Tyrosinase | Homo sapiens (human) | | 5.35 |
Ribosyldihydronicotinamide dehydrogenase [quinone] | Homo sapiens (human) | | 1.3972 |
Nuclear factor NF-kappa-B p105 subunit | Homo sapiens (human) | | 2.5 |
Amine oxidase [flavin-containing] A | Homo sapiens (human) | | 2.4945 |
Prostaglandin G/H synthase 1 | Homo sapiens (human) | | 0.8517 |
Sodium-dependent noradrenaline transporter | Homo sapiens (human) | | 2.312 |
Amine oxidase [flavin-containing] B | Homo sapiens (human) | | 5.01 |
Dipeptidyl peptidase 4 | Homo sapiens (human) | | 0.0006 |
Cytochrome P450 2C19 | Homo sapiens (human) | | 3 |
Prostaglandin G/H synthase 2 | Homo sapiens (human) | | 1.672 |
Prostaglandin G/H synthase 2 | Ovis aries (sheep) | | 3.49 |
Nuclear factor NF-kappa-B p100 subunit | Homo sapiens (human) | | 2.5 |
Transcription factor p65 | Homo sapiens (human) | | 2.5 |
Cytochrome P450 1B1 | Homo sapiens (human) | | 1.4 |
Transient receptor potential cation channel subfamily A member 1 | Rattus norvegicus (Norway rat) | | 1.63 |
large T antigen | Betapolyomavirus macacae | | 26.2 |
Authors | Studies |
Hou, B; Hu, W; Nie, P; Yang, Y; Zhang, T; Zou, Z | 1 |
Abbaspour-Ravasjani, S; Asadollahi, L; Dorreyatim, SS; Hamishehkar, H; Mahoutforoush, A; Paiva-Santos, AC; Peixoto, D; Soltanfam, T; Veiga, F; Zeinali, M | 1 |
Al Hroot, J; Al-Husein, B; Mayyas, A; Zayed, A | 1 |
Article | Year |
Synergistic Induction of Erlotinib-Mediated Apoptosis by Resveratrol in Human Non-Small-Cell Lung Cancer Cells by Down-Regulating Survivin and Up-Regulating PUMA.Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2015, Volume: 35, Issue:6
Topics: Apoptosis; Apoptosis Regulatory Proteins; Carcinoma, Non-Small-Cell Lung; Caspase 3; Cell Line, Tumor; Down-Regulation; Drug Synergism; Erlotinib Hydrochloride; Humans; Inhibitor of Apoptosis Proteins; Lung Neoplasms; Myeloid Cell Leukemia Sequence 1 Protein; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Resveratrol; Ribosomal Protein S6 Kinases; Signal Transduction; Stilbenes; Survivin; TOR Serine-Threonine Kinases; Tumor Suppressor Protein p53; Up-Regulation | 2015 |
Co-Delivery of erlotinib and resveratrol via nanostructured lipid Carriers: A synergistically promising approach for cell proliferation prevention and ROS-Mediated apoptosis activation.International journal of pharmaceutics, 2022, Aug-25, Volume: 624Topics: Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Proliferation; Drug Carriers; Erlotinib Hydrochloride; Humans; Lipids; Lung Neoplasms; Nanostructures; Particle Size; Reactive Oxygen Species; Resveratrol | 2022 |
Rapid high performance liquid chromatography method for erlotinib quantification in vitro: Application to study the effect of resveratrol on metabolism and cellular uptake of erlotinib.Fundamental & clinical pharmacology, 2023, Volume: 37, Issue:5
Topics: Animals; Carcinoma, Non-Small-Cell Lung; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP3A; Erlotinib Hydrochloride; Humans; Lung Neoplasms; Microsomes, Liver; Rats; Resveratrol | 2023 |