Compounds > erlotinib hydrochloride
Page last updated: 2024-09-05

erlotinib hydrochloride and ponatinib

erlotinib hydrochloride has been researched along with ponatinib in 2 studies

Compound Research Comparison

Studies
(erlotinib hydrochloride)		Trials
(erlotinib hydrochloride)		Recent Studies (post-2010)
(erlotinib hydrochloride)		Studies
(ponatinib)		Trials
(ponatinib)		Recent Studies (post-2010) (ponatinib)
4,3537863,03353834519

Protein Interaction Comparison

ProteinTaxonomyerlotinib hydrochloride (IC50)ponatinib (IC50)
Receptor-interacting serine/threonine-protein kinase 2Homo sapiens (human)0.0038
Tyrosine-protein kinase JAK2Homo sapiens (human)0.169
Tyrosine-protein kinase ABL1Homo sapiens (human)0.0037
Proto-oncogene tyrosine-protein kinase SrcGallus gallus (chicken)0.0009
High affinity nerve growth factor receptorHomo sapiens (human)0.0114
Tyrosine-protein kinase LckHomo sapiens (human)0.0003
Tyrosine-protein kinase FynHomo sapiens (human)0.0004
Macrophage colony-stimulating factor 1 receptorHomo sapiens (human)0.0086
Tyrosine-protein kinase YesHomo sapiens (human)0.0009
Tyrosine-protein kinase LynHomo sapiens (human)0.0008
Proto-oncogene tyrosine-protein kinase receptor RetHomo sapiens (human)0.0357
Hepatocyte growth factor receptorHomo sapiens (human)0.0017
Tyrosine-protein kinase HCKHomo sapiens (human)0.0001
Platelet-derived growth factor receptor betaHomo sapiens (human)0.0012
Mast/stem cell growth factor receptor KitHomo sapiens (human)0.0271
Breakpoint cluster region proteinHomo sapiens (human)0.0008
Fibroblast growth factor receptor 1Homo sapiens (human)0.0016
Proto-oncogene tyrosine-protein kinase SrcHomo sapiens (human)0.0053
Platelet-derived growth factor receptor alphaHomo sapiens (human)0.0016
cAMP-dependent protein kinase catalytic subunit alphaHomo sapiens (human)0.613
Vascular endothelial growth factor receptor 1 Homo sapiens (human)0.0123
Ephrin type-A receptor 1Homo sapiens (human)0.143
Fibroblast growth factor receptor 2Homo sapiens (human)0.0018
Fibroblast growth factor receptor 4Homo sapiens (human)0.0058
Fibroblast growth factor receptor 3Homo sapiens (human)0.0099
Tyrosine-protein kinase JAK1Homo sapiens (human)0.0322
Ephrin type-A receptor 2Homo sapiens (human)0.0013
Vascular endothelial growth factor receptor 2Homo sapiens (human)0.0053
Receptor-type tyrosine-protein kinase FLT3Homo sapiens (human)0.0086
Tyrosine-protein kinase CSKHomo sapiens (human)0.0127
Tyrosine-protein kinase FRKHomo sapiens (human)0.0013
Glycogen synthase kinase-3 betaHomo sapiens (human)2.8
Epithelial discoidin domain-containing receptor 1Homo sapiens (human)0.0094
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)4.385
Receptor-interacting serine/threonine-protein kinase 1Homo sapiens (human)0.012
Coiled-coil domain-containing protein 6Homo sapiens (human)0.1804
Mitogen-activated protein kinase 14Homo sapiens (human)0.01
Leucine-rich repeat serine/threonine-protein kinase 2Homo sapiens (human)0.48
Broad substrate specificity ATP-binding cassette transporter ABCG2Homo sapiens (human)0.04
Receptor-interacting serine/threonine-protein kinase 3Homo sapiens (human)0.0016

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Adkins, J; Aldrich, J; Asmann, Y; Baker, A; Barr Fritcher, EG; Barrett, MT; Bhavsar, JD; Bible, KC; Block, M; Borad, MJ; Bryce, AH; Carpten, JD; Champion, MD; Cherni, I; Christoforides, A; Collins, JM; Condjella, RM; Craig, DW; Egan, JB; Fonseca, R; Han, H; Harris, P; Hunt, K; Izatt, T; Kipp, BR; Klee, EW; Kocher, JP; Kurdoglu, A; Lazaridis, KN; Liang, WS; Lobello, J; Mastrian, SD; McCullough, AE; McDonald, J; McWilliams, RR; Middha, S; Nair, AA; Nasser, S; Oliver, GR; Patel, MD; Phillips, L; Placek, P; Reiman, R; Schahl, K; Silva, AC; Stewart, AK; Von Hoff, D; Watanabe, AT; Young, SW1
Cao, Y; Du, P; Kim, HJ; Lee, HJ; Settleman, J; Zhuang, G1

Other Studies

2 other study(ies) available for erlotinib hydrochloride and ponatinib

ArticleYear
Integrated genomic characterization reveals novel, therapeutically relevant drug targets in FGFR and EGFR pathways in sporadic intrahepatic cholangiocarcinoma.
    PLoS genetics, 2014, Volume: 10, Issue:2

    Topics: Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Cell Line, Tumor; Cholangiocarcinoma; ErbB Receptors; Erlotinib Hydrochloride; Genome, Human; Humans; Imidazoles; Indazoles; Molecular Targeted Therapy; Mutation; Prognosis; Protein Kinase Inhibitors; Pyridazines; Pyrimidines; Quinazolines; Receptor, Fibroblast Growth Factor, Type 2; Signal Transduction; Sulfonamides; Transcriptome

2014
Drug resistance via feedback activation of Stat3 in oncogene-addicted cancer cells.
    Cancer cell, 2014, Aug-11, Volume: 26, Issue:2

    Topics: Adenocarcinoma; Adenocarcinoma of Lung; Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Drug Resistance, Neoplasm; ErbB Receptors; Erlotinib Hydrochloride; Humans; Imidazoles; Interleukin-6; Janus Kinase 1; Kaplan-Meier Estimate; Lung Neoplasms; Mice; Mice, SCID; Mutation; Nitriles; Oncogenes; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins p21(ras); Pyrazoles; Pyridazines; Pyrimidines; Quinazolines; ras Proteins; Receptors, Fibroblast Growth Factor; Signal Transduction; STAT3 Transcription Factor; Xenograft Model Antitumor Assays

2014