Page last updated: 2024-09-05

erlotinib hydrochloride and pd 0325901

erlotinib hydrochloride has been researched along with pd 0325901 in 2 studies

Compound Research Comparison

Studies
(erlotinib hydrochloride)
Trials
(erlotinib hydrochloride)
Recent Studies (post-2010)
(erlotinib hydrochloride)
Studies
(pd 0325901)
Trials
(pd 0325901)
Recent Studies (post-2010) (pd 0325901)
4,3537863,0332997256

Protein Interaction Comparison

ProteinTaxonomyerlotinib hydrochloride (IC50)pd 0325901 (IC50)
Cytochrome P450 1A2Homo sapiens (human)0.015
Cytochrome P450 2D6Homo sapiens (human)0.015
Serine/threonine-protein kinase B-rafHomo sapiens (human)0.006
Mitogen-activated protein kinase 1Homo sapiens (human)0.025
Dual specificity mitogen-activated protein kinase kinase 1Mus musculus (house mouse)0.0003
Dual specificity mitogen-activated protein kinase kinase 2Homo sapiens (human)0.078
Dual specificity mitogen-activated protein kinase kinase 1Homo sapiens (human)0.0285

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Al Saleh, S; Khajah, MA; Luqmani, YA; Mathew, PM1
Chinn, DC; Gandara, DR; Holland, WS; Lara, PN; Mack, PC1

Other Studies

2 other study(ies) available for erlotinib hydrochloride and pd 0325901

ArticleYear
Differential effect of growth factors on invasion and proliferation of endocrine resistant breast cancer cells.
    PloS one, 2012, Volume: 7, Issue:7

    Topics: Benzamides; Breast Neoplasms; Cell Movement; Cell Proliferation; Chemokine CCL5; Chromones; Collagenases; Diphenylamine; Epidermal Growth Factor; ErbB Receptors; Erlotinib Hydrochloride; Extracellular Signal-Regulated MAP Kinases; Female; Gene Knockdown Techniques; Humans; Insulin-Like Growth Factor I; Lymphokines; MCF-7 Cells; Morpholines; Phosphorylation; Platelet-Derived Growth Factor; Protein Processing, Post-Translational; Proto-Oncogene Proteins c-akt; Quinazolines; Receptors, Estrogen; RNA, Small Interfering; Transforming Growth Factor beta

2012
Effects of AKT inhibition on HGF-mediated erlotinib resistance in non-small cell lung cancer cell lines.
    Journal of cancer research and clinical oncology, 2015, Volume: 141, Issue:4

    Topics: Apoptosis; Benzamides; Carcinoma, Non-Small-Cell Lung; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Cell Survival; Diphenylamine; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Drug Synergism; ErbB Receptors; Erlotinib Hydrochloride; Flow Cytometry; Hepatocyte Growth Factor; Heterocyclic Compounds, 3-Ring; Humans; Immunoblotting; Lung Neoplasms; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mutation; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Quinazolines; ras Proteins

2015