Page last updated: 2024-09-05

erlotinib hydrochloride and nvp-tae684

erlotinib hydrochloride has been researched along with nvp-tae684 in 1 studies

Compound Research Comparison

Studies
(erlotinib hydrochloride)
Trials
(erlotinib hydrochloride)
Recent Studies (post-2010)
(erlotinib hydrochloride)
Studies
(nvp-tae684)
Trials
(nvp-tae684)
Recent Studies (post-2010) (nvp-tae684)
4,3537863,03374063

Protein Interaction Comparison

ProteinTaxonomyerlotinib hydrochloride (IC50)nvp-tae684 (IC50)
Tyrosine-protein kinase JAK2Homo sapiens (human)1.505
Serine/threonine-protein kinase/endoribonuclease IRE1Homo sapiens (human)0.065
Tyrosine-protein kinase ABL1Homo sapiens (human)1.048
Insulin receptorHomo sapiens (human)2.5164
Tyrosine-protein kinase Fes/FpsHomo sapiens (human)0.569
Macrophage colony-stimulating factor 1 receptorHomo sapiens (human)0.0501
Tyrosine-protein kinase LynHomo sapiens (human)1.308
Proto-oncogene tyrosine-protein kinase receptor RetHomo sapiens (human)1.385
Insulin-like growth factor 1 receptorHomo sapiens (human)0.0003
Hepatocyte growth factor receptorHomo sapiens (human)1.667
Proto-oncogene tyrosine-protein kinase ROSHomo sapiens (human)0.002
Platelet-derived growth factor receptor betaHomo sapiens (human)3.22
Fibroblast growth factor receptor 1Homo sapiens (human)0.6175
Proto-oncogene tyrosine-protein kinase SrcHomo sapiens (human)1.146
Insulin receptor Rattus norvegicus (Norway rat)1.2
Vascular endothelial growth factor receptor 1 Homo sapiens (human)0.872
Fibroblast growth factor receptor 4Homo sapiens (human)0.652
Fibroblast growth factor receptor 3Homo sapiens (human)0.085
Non-receptor tyrosine-protein kinase TYK2Homo sapiens (human)2.309
Vascular endothelial growth factor receptor 2Homo sapiens (human)2.123
Receptor-type tyrosine-protein kinase FLT3Homo sapiens (human)0.7385
Tyrosine-protein kinase ZAP-70Homo sapiens (human)1.598
Cytoplasmic tyrosine-protein kinase BMXHomo sapiens (human)1.578
Ephrin type-B receptor 4Homo sapiens (human)1.3
ALK tyrosine kinase receptorMus musculus (house mouse)0.01
Angiopoietin-1 receptorHomo sapiens (human)0.5895
Macrophage-stimulating protein receptorHomo sapiens (human)1.634
Lysine--tRNA ligaseHomo sapiens (human)0.88
BDNF/NT-3 growth factors receptorHomo sapiens (human)2.018
Leucine-rich repeat serine/threonine-protein kinase 2Homo sapiens (human)0.0323
Echinoderm microtubule-associated protein-like 4Homo sapiens (human)0.03
ALK tyrosine kinase receptorHomo sapiens (human)0.0138

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kita, K; Mano, H; Matsumoto, K; Nakade, J; Nakagawa, T; Nakamura, T; Nanjo, S; Soda, M; Takeuchi, S; Uenaka, T; Yamada, T; Yano, S1

Other Studies

1 other study(ies) available for erlotinib hydrochloride and nvp-tae684

ArticleYear
Paracrine receptor activation by microenvironment triggers bypass survival signals and ALK inhibitor resistance in EML4-ALK lung cancer cells.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2012, Jul-01, Volume: 18, Issue:13

    Topics: Adaptor Proteins, Signal Transducing; Anaplastic Lymphoma Kinase; Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Coculture Techniques; Crizotinib; Drug Resistance, Neoplasm; Endothelial Cells; ErbB Receptors; Erlotinib Hydrochloride; Fibroblasts; Gene Amplification; Hepatocyte Growth Factor; Humans; Intercellular Signaling Peptides and Proteins; Lung Neoplasms; Male; Mice; Mice, SCID; Mutation, Missense; Oncogene Proteins, Fusion; Paracrine Communication; Proto-Oncogene Proteins c-met; Pyrazoles; Pyridines; Pyrimidines; Quinazolines; Receptor Protein-Tyrosine Kinases; Tumor Microenvironment; Xenograft Model Antitumor Assays

2012