Page last updated: 2024-09-05

erlotinib hydrochloride and niclosamide

erlotinib hydrochloride has been researched along with niclosamide in 3 studies

Compound Research Comparison

Studies
(erlotinib hydrochloride)
Trials
(erlotinib hydrochloride)
Recent Studies (post-2010)
(erlotinib hydrochloride)
Studies
(niclosamide)
Trials
(niclosamide)
Recent Studies (post-2010) (niclosamide)
4,3537863,03397919465

Protein Interaction Comparison

ProteinTaxonomyerlotinib hydrochloride (IC50)niclosamide (IC50)
glucose-6-phosphate dehydrogenase-6-phosphogluconolactonasePlasmodium berghei13.7
Tyrosine-protein kinase JAK2Homo sapiens (human)10
Replicase polyprotein 1abSevere acute respiratory syndrome coronavirus 20.28
Proto-oncogene tyrosine-protein kinase SrcHomo sapiens (human)10
Signal transducer and activator of transcription 3Homo sapiens (human)0.23
Anoctamin-1Homo sapiens (human)0.028

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (66.67)24.3611
2020's1 (33.33)2.80

Authors

AuthorsStudies
Chen, ZG; Curran, WJ; Deng, X; Hu, Z; Khuri, FR; Li, R; Owonikoko, TK; Ramalingam, SS; Sica, GL; Sun, SY1
Chen, ZG; Curran, WJ; Deng, X; Hu, Z; Khuri, FR; Li, R; Shin, DM; Sica, GL; You, S1
Chella, N; Kumar, P; Padakanti, AP; Pawar, SD1

Other Studies

3 other study(ies) available for erlotinib hydrochloride and niclosamide

ArticleYear
Niclosamide overcomes acquired resistance to erlotinib through suppression of STAT3 in non-small cell lung cancer.
    Molecular cancer therapeutics, 2013, Volume: 12, Issue:10

    Topics: Apoptosis; bcl-X Protein; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Drug Resistance, Neoplasm; ErbB Receptors; Erlotinib Hydrochloride; Gene Expression Regulation, Neoplastic; Humans; Mutation; Niclosamide; Phosphorylation; Proto-Oncogene Proteins c-bcl-2; Quinazolines; Signal Transduction; STAT3 Transcription Factor; Xenograft Model Antitumor Assays

2013
Inhibition of STAT3 by niclosamide synergizes with erlotinib against head and neck cancer.
    PloS one, 2013, Volume: 8, Issue:9

    Topics: Antineoplastic Agents; Base Sequence; Cell Line, Tumor; DNA Primers; Drug Synergism; ErbB Receptors; Erlotinib Hydrochloride; Head and Neck Neoplasms; Humans; Niclosamide; Phosphorylation; Quinazolines; Reverse Transcriptase Polymerase Chain Reaction; STAT3 Transcription Factor

2013
Development and validation of HPLC method for simultaneous estimation of erlotinib and niclosamide from liposomes optimized by screening design.
    Journal of liposome research, 2023, Volume: 33, Issue:3

    Topics: Chromatography, High Pressure Liquid; Drug Liberation; Erlotinib Hydrochloride; Liposomes; Niclosamide; Particle Size

2023