Compounds > erlotinib hydrochloride
Page last updated: 2024-09-05

erlotinib hydrochloride and lonafarnib

erlotinib hydrochloride has been researched along with lonafarnib in 2 studies

Compound Research Comparison

Studies
(erlotinib hydrochloride)		Trials
(erlotinib hydrochloride)		Recent Studies (post-2010)
(erlotinib hydrochloride)		Studies
(lonafarnib)		Trials
(lonafarnib)		Recent Studies (post-2010) (lonafarnib)
4,3537863,0332243490

Protein Interaction Comparison

ProteinTaxonomyerlotinib hydrochloride (IC50)lonafarnib (IC50)
Chain A, Protein farnesyltransferase alpha subunitRattus norvegicus (Norway rat)0.0019
Chain B, Protein farnesyltransferase beta subunitRattus norvegicus (Norway rat)0.0019
GTPase HRasHomo sapiens (human)0.07
ATP-dependent translocase ABCB1Homo sapiens (human)2.7
Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alphaBos taurus (cattle)0.0081
Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alphaHomo sapiens (human)0.1498
Protein farnesyltransferase subunit betaBos taurus (cattle)0.0081
Protein farnesyltransferase subunit betaHomo sapiens (human)0.1498
Protein farnesyltransferase subunit betaRattus norvegicus (Norway rat)0.0019
Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alphaRattus norvegicus (Norway rat)0.0019

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kurisu, K; Okamura, T1
Bernhard, JC; Ferrière, JM; Ravaud, A; Robert, G; Wallerand, H1

Reviews

2 review(s) available for erlotinib hydrochloride and lonafarnib

ArticleYear
[Molecular targeted therapy for malignant brain tumors].
    Nihon rinsho. Japanese journal of clinical medicine, 2005, Volume: 63 Suppl 9

    Topics: Antineoplastic Agents; Benzamides; Brain Neoplasms; Drug Delivery Systems; Drug Design; Drug Resistance, Neoplasm; Drug Therapy, Combination; ErbB Receptors; Erlotinib Hydrochloride; Gefitinib; Glioma; Humans; Imatinib Mesylate; Intracellular Signaling Peptides and Proteins; Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Piperazines; Piperidines; Protein Kinases; Protein-Tyrosine Kinases; Pyridines; Pyrimidines; Quinazolines; Signal Transduction; Sirolimus; TOR Serine-Threonine Kinases

2005
[Targeted therapy for locally advanced and/or metastatic bladder cancer].
    Progres en urologie : journal de l'Association francaise d'urologie et de la Societe francaise d'urologie, 2008, Volume: 18, Issue:7

    Topics: Angiogenesis Inhibitors; Antibiotics, Antineoplastic; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Bevacizumab; Disease Progression; Erlotinib Hydrochloride; Gefitinib; Genetic Therapy; Humans; Immunosuppressive Agents; Mutation; Piperidines; Protein Kinase Inhibitors; Pyridines; Quinazolines; Randomized Controlled Trials as Topic; Signal Transduction; Sirolimus; Targeted Gene Repair; Trastuzumab; Urinary Bladder Neoplasms

2008