Page last updated: 2024-09-05

erlotinib hydrochloride and glutaminase

erlotinib hydrochloride has been researched along with glutaminase in 2 studies

Compound Research Comparison

Studies (erlotinib hydrochloride)	Trials (erlotinib hydrochloride)	Recent Studies (post-2010) (erlotinib hydrochloride)	Studies (glutaminase)	Trials (glutaminase)	Recent Studies (post-2010) (glutaminase)
4,353	786	3,033	2,301	11	738

Protein Interaction Comparison

Protein	Taxonomy	erlotinib hydrochloride (IC50)	glutaminase (IC50)
Protein-glutamine gamma-glutamyltransferase 2	Homo sapiens (human)		0.045

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	2 (100.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Bao, X; Gan, M; Han, TY; Jin, J; Wang, J; Xie, C; Zhan, WH; Zhang, C	1
Bailey, ST; Braas, D; Christofk, HR; Czernin, J; Demo, S; Dubinett, SM; Emberley, E; Fishbein, MC; Garon, E; Graeber, T; Gross, M; Jackson, NJ; Janes, J; Krysan, K; Lee, JT; Mackinnon, A; Magyar, C; Momcilovic, M; Pan, A; Parlati, F; Rodriguez, M; Sadeghi, S; Shackelford, DB; Walser, TC; Works, M; Zhang, W	1

Other Studies

2 other study(ies) available for erlotinib hydrochloride and glutaminase

Article	Year
Inhibition of mitochondrial glutaminase activity reverses acquired erlotinib resistance in non-small cell lung cancer. Oncotarget, 2016, Jan-05, Volume: 7, Issue:1 Topics: Apoptosis; Benzophenanthridines; Blotting, Western; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Erlotinib Hydrochloride; Flow Cytometry; Glutaminase; Humans; Lung Neoplasms; Mitochondria; Protein Kinase Inhibitors; RNA Interference; Time Factors	2016
Targeted Inhibition of EGFR and Glutaminase Induces Metabolic Crisis in EGFR Mutant Lung Cancer. Cell reports, 2017, 01-17, Volume: 18, Issue:3 Topics: AMP-Activated Protein Kinases; Animals; Apoptosis; Autophagy; Benzeneacetamides; Carbon Radioisotopes; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; ErbB Receptors; Erlotinib Hydrochloride; Fluorodeoxyglucose F18; Glutaminase; Glutamine; Humans; Lung Neoplasms; Mice; Mice, SCID; Mutation; Radiopharmaceuticals; RNA Interference; Thiadiazoles; Transplantation, Heterologous	2017

Article

Year

Inhibition of mitochondrial glutaminase activity reverses acquired erlotinib resistance in non-small cell lung cancer.

Oncotarget, 2016, Jan-05, Volume: 7, Issue:1

Topics: Apoptosis; Benzophenanthridines; Blotting, Western; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Erlotinib Hydrochloride; Flow Cytometry; Glutaminase; Humans; Lung Neoplasms; Mitochondria; Protein Kinase Inhibitors; RNA Interference; Time Factors

2016

Targeted Inhibition of EGFR and Glutaminase Induces Metabolic Crisis in EGFR Mutant Lung Cancer.

Cell reports, 2017, 01-17, Volume: 18, Issue:3

Topics: AMP-Activated Protein Kinases; Animals; Apoptosis; Autophagy; Benzeneacetamides; Carbon Radioisotopes; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; ErbB Receptors; Erlotinib Hydrochloride; Fluorodeoxyglucose F18; Glutaminase; Glutamine; Humans; Lung Neoplasms; Mice; Mice, SCID; Mutation; Radiopharmaceuticals; RNA Interference; Thiadiazoles; Transplantation, Heterologous

2017