Compounds > erlotinib hydrochloride
Page last updated: 2024-09-05

erlotinib hydrochloride and genistein

erlotinib hydrochloride has been researched along with genistein in 4 studies

Compound Research Comparison

Studies
(erlotinib hydrochloride)		Trials
(erlotinib hydrochloride)		Recent Studies (post-2010)
(erlotinib hydrochloride)		Studies
(genistein)		Trials
(genistein)		Recent Studies (post-2010) (genistein)
4,3537863,0337,4232042,311

Protein Interaction Comparison

ProteinTaxonomyerlotinib hydrochloride (IC50)genistein (IC50)
Chain A, Estrogen receptor 1 (alpha)Homo sapiens (human)0.009
Maltase-glucoamylase, intestinalHomo sapiens (human)2.61
Steroid hormone receptor ERR2Homo sapiens (human)0.395
Tyrosine-protein kinase ABL1Homo sapiens (human)5.5
Epidermal growth factor receptorHomo sapiens (human)1.2
TransthyretinHomo sapiens (human)7.8
Estrogen receptorHomo sapiens (human)1.3477
Steroid hormone receptor ERR1Homo sapiens (human)0.01
Polyunsaturated fatty acid lipoxygenase ALOX15Oryctolagus cuniculus (rabbit)9.033
17-beta-hydroxysteroid dehydrogenase type 1Homo sapiens (human)2.21
Protein kinase C alpha typeHomo sapiens (human)1
cAMP-dependent protein kinase catalytic subunit alphaHomo sapiens (human)1
Amine oxidase [flavin-containing] AHomo sapiens (human)4.184
Thromboxane-A synthase Homo sapiens (human)7.72
Amine oxidase [flavin-containing] BHomo sapiens (human)3.9333
Dipeptidyl peptidase 4Homo sapiens (human)0.48
Proteasome subunit beta type-5Homo sapiens (human)9.26
Sodium-dependent serotonin transporterRattus norvegicus (Norway rat)0.395
Tyrosine-protein kinase CSKHomo sapiens (human)1
Dual specificity mitogen-activated protein kinase kinase 4Homo sapiens (human)0.4
Xanthine dehydrogenase/oxidaseBos taurus (cattle)1.73
Aldehyde oxidaseHomo sapiens (human)0.34
Integrase Human immunodeficiency virus 11.1
Estrogen receptor betaHomo sapiens (human)0.3706
Beta-hydroxyacyl-ACP dehydratase precursor (Fatty acid synthesis protein)Plasmodium falciparum (malaria parasite P. falciparum)7
Solute carrier organic anion transporter family member 1B3Homo sapiens (human)3.8905
Broad substrate specificity ATP-binding cassette transporter ABCG2Homo sapiens (human)7.85
Solute carrier organic anion transporter family member 1B1Homo sapiens (human)9.1201

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (50.00)29.6817
2010's2 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Abbruzzese, J; Ali, IF; Ali, S; El-Rayes, BF; Philip, PA; Sarkar, FH1
Ali, S; Gadgeel, SM; Philip, PA; Sarkar, FH; Wozniak, A1
Aichinger, G; Berger, W; Marko, D; Nagel, LJ; Pahlke, G1
Nimmano, N; Somavarapu, S; Taylor, KMG1

Other Studies

4 other study(ies) available for erlotinib hydrochloride and genistein

ArticleYear
Potentiation of the effect of erlotinib by genistein in pancreatic cancer: the role of Akt and nuclear factor-kappaB.
    Cancer research, 2006, Nov-01, Volume: 66, Issue:21

    Topics: Apoptosis; Cell Line, Tumor; Cell Survival; Deoxycytidine; Drug Synergism; ErbB Receptors; Erlotinib Hydrochloride; Gemcitabine; Genistein; Humans; NF-kappa B; Pancreatic Neoplasms; Phosphorylation; Proto-Oncogene Proteins c-akt; Quinazolines; Signal Transduction

2006
Genistein enhances the effect of epidermal growth factor receptor tyrosine kinase inhibitors and inhibits nuclear factor kappa B in nonsmall cell lung cancer cell lines.
    Cancer, 2009, May-15, Volume: 115, Issue:10

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Cyclooxygenase 2; Dinoprostone; ErbB Receptors; Erlotinib Hydrochloride; Gefitinib; Genistein; Humans; Lung Neoplasms; NF-kappa B; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Quinazolines

2009
Bilberry extract, its major polyphenolic compounds, and the soy isoflavone genistein antagonize the cytostatic drug erlotinib in human epithelial cells.
    Food & function, 2016, Aug-10, Volume: 7, Issue:8

    Topics: Anthocyanins; Cell Line, Tumor; Cytostatic Agents; Epithelial Cells; ErbB Receptors; Erlotinib Hydrochloride; Gallic Acid; Genistein; Glucosides; Glycine max; Humans; Phloroglucinol; Phosphorylation; Plant Extracts; Polyphenols; Vaccinium myrtillus

2016
Aerosol characterisation of nebulised liposomes co-loaded with erlotinib and genistein using an abbreviated cascade impactor method.
    International journal of pharmaceutics, 2018, May-05, Volume: 542, Issue:1-2

    Topics: Aerosols; Erlotinib Hydrochloride; Genistein; Liposomes; Nebulizers and Vaporizers; Particle Size; Technology, Pharmaceutical

2018