Page last updated: 2024-09-05

erlotinib hydrochloride and entinostat

erlotinib hydrochloride has been researched along with entinostat in 1 studies

Compound Research Comparison

Studies
(erlotinib hydrochloride)
Trials
(erlotinib hydrochloride)
Recent Studies (post-2010)
(erlotinib hydrochloride)
Studies
(entinostat)
Trials
(entinostat)
Recent Studies (post-2010) (entinostat)
4,3537863,03355731402

Protein Interaction Comparison

ProteinTaxonomyerlotinib hydrochloride (IC50)entinostat (IC50)
Histone deacetylase 3Homo sapiens (human)1.5547
Cytochrome P450 3A4Homo sapiens (human)0.73
Tissue factorHomo sapiens (human)8
Cytochrome P450 2C19Homo sapiens (human)3.93
Histone deacetylase 4Homo sapiens (human)2.5077
Histone deacetylase 1Homo sapiens (human)1.0631
Histone deacetylase 7Homo sapiens (human)2.7679
Histone deacetylase 2Homo sapiens (human)1.4517
Polyamine deacetylase HDAC10Homo sapiens (human)3.1451
Histone deacetylase 11 Homo sapiens (human)3.3762
Histone deacetylase 8Homo sapiens (human)3.5118
Histone deacetylase 6Homo sapiens (human)2.9645
Histone deacetylase 9Homo sapiens (human)2.9949
Histone deacetylase 5Homo sapiens (human)2.7109
Histone deacetylase Plasmodium falciparum (malaria parasite P. falciparum)0.94
Nuclear receptor corepressor 2Homo sapiens (human)1.185

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bunn, PA; Hirsch, FR; Jotte, RM; Konduri, K; Neubauer, MA; Ruxer, RL; Spira, AI; Varella-Garcia, M; Witta, SE1

Trials

1 trial(s) available for erlotinib hydrochloride and entinostat

ArticleYear
Randomized phase II trial of erlotinib with and without entinostat in patients with advanced non-small-cell lung cancer who progressed on prior chemotherapy.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2012, Jun-20, Volume: 30, Issue:18

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Biomarkers, Tumor; Cadherins; Carcinoma, Non-Small-Cell Lung; Erlotinib Hydrochloride; Female; Histone Deacetylase Inhibitors; Humans; Lung Neoplasms; Male; Middle Aged; Pyridines; Quinazolines

2012