Page last updated: 2024-09-05

erlotinib hydrochloride and dinaciclib

erlotinib hydrochloride has been researched along with dinaciclib in 1 studies

Compound Research Comparison

Studies
(erlotinib hydrochloride)
Trials
(erlotinib hydrochloride)
Recent Studies (post-2010)
(erlotinib hydrochloride)
Studies
(dinaciclib)
Trials
(dinaciclib)
Recent Studies (post-2010) (dinaciclib)
4,3537863,03313312129

Protein Interaction Comparison

ProteinTaxonomyerlotinib hydrochloride (IC50)dinaciclib (IC50)
Cyclin-T1Homo sapiens (human)0.0272
Cyclin-KHomo sapiens (human)0.0227
Cyclin-dependent kinase 1Homo sapiens (human)0.0162
Cyclin-dependent kinase 4Homo sapiens (human)0.0742
G2/mitotic-specific cyclin-B1Homo sapiens (human)0.049
Cyclin-A2Homo sapiens (human)0.002
G1/S-specific cyclin-D1Homo sapiens (human)0.119
G1/S-specific cyclin-E1Homo sapiens (human)0.0028
Cyclin-dependent kinase 2Homo sapiens (human)0.0074
Aldo-keto reductase family 1 member C3Homo sapiens (human)0.23
Cyclin-dependent kinase 8Homo sapiens (human)0.0039
Glycogen synthase kinase-3 alphaHomo sapiens (human)0.414
Glycogen synthase kinase-3 betaHomo sapiens (human)0.324
Cyclin-dependent kinase 7Homo sapiens (human)0.1273
Cyclin-dependent kinase 9Homo sapiens (human)0.0227
Cyclin-HHomo sapiens (human)0.17
CDK-activating kinase assembly factor MAT1Homo sapiens (human)0.17
Cyclin-A1Homo sapiens (human)0.003
Cyclin-dependent-like kinase 5 Homo sapiens (human)0.011
Heat shock factor protein 1Homo sapiens (human)0.007
Cyclin-dependent kinase 13Homo sapiens (human)0.021
Cyclin-dependent kinase 5 activator 1Homo sapiens (human)0.0219
Cyclin-dependent kinase 12Homo sapiens (human)0.0323

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bannerji, R; Edelman, MJ; Jou, YM; Joy, AA; Martin, JC; Nemunaitis, J; Small, K; Statkevich, P; Stephenson, JJ; Yao, SL; Zhang, D; Zhou, H; Zhu, Y1

Trials

1 trial(s) available for erlotinib hydrochloride and dinaciclib

ArticleYear
Randomized phase 2 study of the cyclin-dependent kinase inhibitor dinaciclib (MK-7965) versus erlotinib in patients with non-small cell lung cancer.
    Lung cancer (Amsterdam, Netherlands), 2014, Volume: 83, Issue:2

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bridged Bicyclo Compounds, Heterocyclic; Carcinoma, Non-Small-Cell Lung; Cyclic N-Oxides; Cyclin-Dependent Kinases; Disease-Free Survival; ErbB Receptors; Erlotinib Hydrochloride; Female; Follow-Up Studies; Humans; Indolizines; Injections, Intravenous; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Neutropenia; Pyridinium Compounds; Quinazolines

2014