Page last updated: 2024-09-05

erlotinib hydrochloride and dabrafenib

erlotinib hydrochloride has been researched along with dabrafenib in 5 studies

Compound Research Comparison

Studies
(erlotinib hydrochloride)
Trials
(erlotinib hydrochloride)
Recent Studies (post-2010)
(erlotinib hydrochloride)
Studies
(dabrafenib)
Trials
(dabrafenib)
Recent Studies (post-2010) (dabrafenib)
4,3537863,033825107808

Protein Interaction Comparison

ProteinTaxonomyerlotinib hydrochloride (IC50)dabrafenib (IC50)
Receptor-interacting serine/threonine-protein kinase 2Homo sapiens (human)0.077
GTPase KRasHomo sapiens (human)5.88
RAF proto-oncogene serine/threonine-protein kinaseHomo sapiens (human)0.15
Serine/threonine-protein kinase A-RafHomo sapiens (human)0.026
Serine/threonine-protein kinase B-rafHomo sapiens (human)0.0033
TGF-beta receptor type-1Homo sapiens (human)3.7
Receptor-interacting serine/threonine-protein kinase 3Homo sapiens (human)0.126

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (60.00)24.3611
2020's2 (40.00)2.80

Authors

AuthorsStudies
Yaqub, F1
Azan, A; Bakker Schut, TC; Besse, B; Boutros, C; Caspers, PJ; Eggermont, AM; Kamsu Kom, N; Koljenović, S; Lanoy, E; Mateus, C; Mir, LM; Noordhoek Hegt, V; Paci, A; Planchard, D; Puppels, GJ; Robert, C; Routier, E; Roy, S; Seck, A; Texier, M; Tomasic, G1
Brown, B; Molloy, MP; Neilson, KA; Semaan, C1
Niederer, R; Samalia, P; Sims, J1
Choi, YS; Jeon, MJ; Kim, TY; Kim, WB; Kim, WG; Kwon, H; Shong, YK; You, MH1

Trials

1 trial(s) available for erlotinib hydrochloride and dabrafenib

ArticleYear
A Novel Spectroscopically Determined Pharmacodynamic Biomarker for Skin Toxicity in Cancer Patients Treated with Targeted Agents.
    Cancer research, 2017, 01-15, Volume: 77, Issue:2

    Topics: Aged; Algorithms; Antineoplastic Agents; Area Under Curve; Biomarkers; Drug Eruptions; Erlotinib Hydrochloride; Female; Humans; Imidazoles; Indoles; Male; Middle Aged; Oximes; Pilot Projects; Protein Kinase Inhibitors; Pyridones; Pyrimidinones; ROC Curve; Sensitivity and Specificity; Skin; Spectrum Analysis, Raman; Sulfonamides; Vemurafenib

2017

Other Studies

4 other study(ies) available for erlotinib hydrochloride and dabrafenib

ArticleYear
American Society of Clinical Oncology Annual Meeting 2013.
    The Lancet. Respiratory medicine, 2013, Volume: 1, Issue:5

    Topics: Antibodies, Monoclonal; Antineoplastic Agents; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Docetaxel; Erlotinib Hydrochloride; Female; Humans; Imidazoles; Indoles; Lung Neoplasms; Male; Medical Oncology; Multicenter Studies as Topic; Oximes; Protein Kinase Inhibitors; Pyrimidines; Pyrroles; Quinazolines; Randomized Controlled Trials as Topic; Small Cell Lung Carcinoma; Societies, Medical; Sulfones; Sunitinib; Taxoids; Treatment Outcome; Triazoles; United States

2013
Pharmacological Inhibition of Casein Kinase 2 Enhances the Effectiveness of PI3K Inhibition in Colon Cancer Cells.
    Anticancer research, 2018, Volume: 38, Issue:11

    Topics: Casein Kinase II; Cell Line, Tumor; Cell Proliferation; Cell Survival; Colonic Neoplasms; Drug Synergism; Erlotinib Hydrochloride; Gene Expression Regulation, Neoplastic; HT29 Cells; Humans; Imidazoles; Indazoles; MAP Kinase Signaling System; Mutation; Naphthyridines; Oximes; Phenazines; Phosphoinositide-3 Kinase Inhibitors; Proto-Oncogene Mas; Proto-Oncogene Proteins B-raf; Sulfonamides

2018
Drug-induced ocular inflammation.
    The New Zealand medical journal, 2020, 12-18, Volume: 133, Issue:1527

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Alendronate; Allopurinol; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal, Humanized; Antihypertensive Agents; Brimonidine Tartrate; Diphosphonates; ErbB Receptors; Erlotinib Hydrochloride; Etanercept; Female; Humans; Imidazoles; Immune Checkpoint Inhibitors; Male; Middle Aged; Nivolumab; Oximes; Protein Kinase Inhibitors; Proto-Oncogene Proteins B-raf; Retrospective Studies; Scleritis; Uveitis, Anterior; Vemurafenib; Zoledronic Acid

2020
Effects of dabrafenib and erlotinib combination treatment on anaplastic thyroid carcinoma.
    Endocrine-related cancer, 2022, 05-09, Volume: 29, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; ErbB Receptors; Erlotinib Hydrochloride; Humans; Imidazoles; Mitogen-Activated Protein Kinase Kinases; Mutation; Oximes; Protein Kinase Inhibitors; Proto-Oncogene Proteins B-raf; Thyroid Carcinoma, Anaplastic; Thyroid Neoplasms

2022