Compounds > erlotinib hydrochloride
Page last updated: 2024-09-05

erlotinib hydrochloride and curcumin

erlotinib hydrochloride has been researched along with curcumin in 4 studies

Compound Research Comparison

Studies
(erlotinib hydrochloride)		Trials
(erlotinib hydrochloride)		Recent Studies (post-2010)
(erlotinib hydrochloride)		Studies
(curcumin)		Trials
(curcumin)		Recent Studies (post-2010) (curcumin)
4,3537863,03316,33659312,705

Protein Interaction Comparison

ProteinTaxonomyerlotinib hydrochloride (IC50)curcumin (IC50)
toll-like receptor 9Homo sapiens (human)8.362
TPA: protein transporter TIM10Saccharomyces cerevisiae S288C19.7
intestinal alkaline phosphatase precursorMus musculus (house mouse)18.7
perilipin-1Homo sapiens (human)9.167
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform aHomo sapiens (human)9.167
hypothetical protein SA1422Staphylococcus aureus subsp. aureus N31542.9
Prostaglandin E synthaseHomo sapiens (human)1.8
Lysine-specific histone demethylase 1AHomo sapiens (human)9.6
D-amino-acid oxidaseSus scrofa (pig)1.07
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1Oryctolagus cuniculus (rabbit)3
Amyloid-beta precursor proteinHomo sapiens (human)4.3079
Neuronal proto-oncogene tyrosine-protein kinase Src Mus musculus (house mouse)2.2
Heme oxygenase 1 Rattus norvegicus (Norway rat)10
Microtubule-associated protein tauHomo sapiens (human)3.25
60 kDa heat shock protein, mitochondrialHomo sapiens (human)8.3
Tissue factorHomo sapiens (human)0.0132
TyrosinaseHomo sapiens (human)5
Alpha-1B adrenergic receptorRattus norvegicus (Norway rat)5.4
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2Homo sapiens (human)7
Glycogen synthase kinase-3 betaRattus norvegicus (Norway rat)0.066
Amine oxidase [flavin-containing] AHomo sapiens (human)3.5
Heme oxygenase 2Rattus norvegicus (Norway rat)10
Alpha-1D adrenergic receptorRattus norvegicus (Norway rat)5.4
Amine oxidase [flavin-containing] BHomo sapiens (human)2.5733
Proteasome subunit beta type-5Homo sapiens (human)10
17-beta-hydroxysteroid dehydrogenase type 2Homo sapiens (human)1.73
Alpha-synucleinHomo sapiens (human)0.22
Alpha-1A adrenergic receptorRattus norvegicus (Norway rat)5.4
10 kDa heat shock protein, mitochondrialHomo sapiens (human)8.3
Histone acetyltransferase p300Homo sapiens (human)6.5
60 kDa chaperonin Escherichia coli3
10 kDa chaperonin Escherichia coli3
Sarcoplasmic/endoplasmic reticulum calcium ATPase 3Homo sapiens (human)7
Cysteine protease Trypanosoma brucei rhodesiense7.75
CDGSH iron-sulfur domain-containing protein 1Homo sapiens (human)2.36
Broad substrate specificity ATP-binding cassette transporter ABCG2Homo sapiens (human)1.63
Beta lactamase (plasmid)Pseudomonas aeruginosa7.751

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (50.00)24.3611
2020's2 (50.00)2.80

Authors

AuthorsStudies
Izumi, Y; Nomori, H; Yamamoto, J; Yamauchi, Y1
Fan, X; Jiang, L; Li, S; Liu, Z; Wu, X; Zhao, H; Zhu, F1
Cheng, C; Hu, X; Shi, S; Sui, B; Wang, M; Xu, P1
Bagherian, A; Masoudian, N; Mirzaei, H; Roudi, B1

Other Studies

4 other study(ies) available for erlotinib hydrochloride and curcumin

ArticleYear
Coadministration of erlotinib and curcumin augmentatively reduces cell viability in lung cancer cells.
    Phytotherapy research : PTR, 2014, Volume: 28, Issue:5

    Topics: Animals; Apoptosis; Cell Line, Tumor; Cell Survival; Curcumin; Erlotinib Hydrochloride; Humans; I-kappa B Proteins; Lung Neoplasms; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Quinazolines; RNA Interference

2014
Curcumin lowers erlotinib resistance in non-small cell lung carcinoma cells with mutated EGF receptor.
    Oncology research, 2013, Volume: 21, Issue:3

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Curcumin; Down-Regulation; Drug Resistance, Neoplasm; Drug Synergism; ErbB Receptors; Erlotinib Hydrochloride; Female; Humans; Inhibitor of Apoptosis Proteins; Lung Neoplasms; Mice; Mice, Nude; Mutation; Quinazolines; Random Allocation; Survivin; Xenograft Model Antitumor Assays

2013
Carrier-Free Nanoassembly of Curcumin-Erlotinib Conjugate for Cancer Targeted Therapy.
    Advanced healthcare materials, 2020, Volume: 9, Issue:19

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Curcumin; Erlotinib Hydrochloride; Mice; Nanoparticles; Pancreatic Neoplasms; Xenograft Model Antitumor Assays

2020
Anti-glioblastoma effects of nanomicelle-curcumin plus erlotinib.
    Food & function, 2021, Nov-01, Volume: 12, Issue:21

    Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Movement; Curcumin; Erlotinib Hydrochloride; Gene Expression Regulation, Neoplastic; Glioblastoma; Humans; Micelles; Nanostructures

2021