Page last updated: 2024-09-05

erlotinib hydrochloride and cudc 101

erlotinib hydrochloride has been researched along with cudc 101 in 2 studies

Compound Research Comparison

Studies
(erlotinib hydrochloride)
Trials
(erlotinib hydrochloride)
Recent Studies (post-2010)
(erlotinib hydrochloride)
Studies
(cudc 101)
Trials
(cudc 101)
Recent Studies (post-2010) (cudc 101)
4,3537863,03339235

Protein Interaction Comparison

ProteinTaxonomyerlotinib hydrochloride (IC50)cudc 101 (IC50)
Histone deacetylase 3Homo sapiens (human)0.1561
Tyrosine-protein kinase ABL1Homo sapiens (human)2.89
Epidermal growth factor receptorHomo sapiens (human)0.0046
Receptor tyrosine-protein kinase erbB-2Homo sapiens (human)0.0525
Tyrosine-protein kinase LckHomo sapiens (human)5.91
Tyrosine-protein kinase LynHomo sapiens (human)0.84
Proto-oncogene tyrosine-protein kinase receptor RetHomo sapiens (human)3.2
Fibroblast growth factor receptor 2Homo sapiens (human)3.43
Vascular endothelial growth factor receptor 2Homo sapiens (human)0.849
Receptor-type tyrosine-protein kinase FLT3Homo sapiens (human)1.5
Histone deacetylase 4Homo sapiens (human)0.1567
Fatty-acid amide hydrolase 1Rattus norvegicus (Norway rat)3.7086
Histone deacetylase 1Homo sapiens (human)0.1554
Histone deacetylase 7Homo sapiens (human)0.2081
Histone deacetylase 2Homo sapiens (human)0.1566
Polyamine deacetylase HDAC10Homo sapiens (human)0.1815
Histone deacetylase 11 Homo sapiens (human)0.1806
Histone deacetylase 8Homo sapiens (human)0.1662
Histone deacetylase 6Homo sapiens (human)0.1555
Histone deacetylase 9Homo sapiens (human)0.1644
Histone deacetylase 5Homo sapiens (human)0.1564

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Atoyan, R; Cai, X; Lai, CJ; Ma, AW; Pursell, NW; Samson, ME; Savagner, P; Selmi, A; Voi, M; Wang, J; Xu, W1
Biswas, L; Keechilat, P; Melge, AR; Mohan, CG; Panicker, PS1

Other Studies

2 other study(ies) available for erlotinib hydrochloride and cudc 101

ArticleYear
Potential advantages of CUDC-101, a multitargeted HDAC, EGFR, and HER2 inhibitor, in treating drug resistance and preventing cancer cell migration and invasion.
    Molecular cancer therapeutics, 2013, Volume: 12, Issue:6

    Topics: Cadherins; Cell Line, Tumor; Cell Movement; Drug Resistance, Neoplasm; ErbB Receptors; Erlotinib Hydrochloride; Gene Expression Regulation, Neoplastic; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Hydroxamic Acids; Neoplasm Invasiveness; Proto-Oncogene Proteins c-met; Quinazolines; Receptor, ErbB-2; Stomach Neoplasms

2013
Epidermal growth factor receptor (EGFR) structure-based bioactive pharmacophore models for identifying next-generation inhibitors against clinically relevant EGFR mutations.
    Chemical biology & drug design, 2017, Volume: 90, Issue:4

    Topics: Antineoplastic Agents; Computer-Aided Design; Databases, Pharmaceutical; Drug Design; ErbB Receptors; Erlotinib Hydrochloride; Gefitinib; Humans; Hydroxamic Acids; Molecular Docking Simulation; Mutation; Protein Kinase Inhibitors; Quantitative Structure-Activity Relationship; Quinazolines; Small Molecule Libraries

2017