erlotinib hydrochloride has been researched along with aminopterin in 1 studies
| Studies (erlotinib hydrochloride) | Trials (erlotinib hydrochloride) | Recent Studies (post-2010) (erlotinib hydrochloride) | Studies (aminopterin) | Trials (aminopterin) | Recent Studies (post-2010) (aminopterin) |
|---|---|---|---|---|---|
| 4,353 | 786 | 3,033 | 1,389 | 73 | 109 |
| Protein | Taxonomy | erlotinib hydrochloride (IC50) | aminopterin (IC50) |
|---|---|---|---|
| Dihydrofolate reductase | Homo sapiens (human) | 0.0201 | |
| Dihydrofolate reductase | Mus musculus (house mouse) | 0.0253 | |
| Dihydrofolate reductase | Lacticaseibacillus casei | 0.005 | |
| Dihydrofolate reductase | Escherichia coli K-12 | 0.011 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Albert, I; Azzoli, CG; Bodkin, D; Iannotti, NO; Jiang, PY; Juhász, E; Kelly, K; Koutsoukos, T; Patel, JD; Pereira, JR; Weems, G; Zatloukal, P | 1 |
1 trial(s) available for erlotinib hydrochloride and aminopterin
| Article | Year |
|---|---|
Randomized phase 2b study of pralatrexate versus erlotinib in patients with stage IIIB/IV non-small-cell lung cancer (NSCLC) after failure of prior platinum-based therapy.
Topics: Adult; Aged; Aged, 80 and over; Aminopterin; Carcinoma, Non-Small-Cell Lung; Disease-Free Survival; Dose-Response Relationship, Drug; ErbB Receptors; Erlotinib Hydrochloride; Female; Folic Acid Antagonists; Follow-Up Studies; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Platinum; Protein Kinase Inhibitors; Quinazolines; Retrospective Studies; Survival Rate; Treatment Failure; United States | 2012 |