Page last updated: 2024-09-05

erlotinib hydrochloride and abemaciclib

erlotinib hydrochloride has been researched along with abemaciclib in 1 studies

Compound Research Comparison

Studies
(erlotinib hydrochloride)
Trials
(erlotinib hydrochloride)
Recent Studies (post-2010)
(erlotinib hydrochloride)
Studies
(abemaciclib)
Trials
(abemaciclib)
Recent Studies (post-2010) (abemaciclib)
4,3537863,03335243343

Protein Interaction Comparison

ProteinTaxonomyerlotinib hydrochloride (IC50)abemaciclib (IC50)
Cyclin-T1Homo sapiens (human)0.0734
Cyclin-KHomo sapiens (human)0.065
Cyclin-dependent kinase 1Homo sapiens (human)0.7586
Replicase polyprotein 1abSevere acute respiratory syndrome coronavirus 26.62
Cyclin-dependent kinase 4Homo sapiens (human)0.0097
G2/mitotic-specific cyclin-B1Homo sapiens (human)0.7484
Cyclin-A2Homo sapiens (human)0.1036
G1/S-specific cyclin-D1Homo sapiens (human)0.0048
G1/S-specific cyclin-E1Homo sapiens (human)0.232
Cyclin-dependent kinase 2Homo sapiens (human)0.1847
G1/S-specific cyclin-D3Homo sapiens (human)0.0112
Cyclin-dependent kinase 7Homo sapiens (human)2.027
Cyclin-dependent kinase 9Homo sapiens (human)0.0693
Cyclin-HHomo sapiens (human)2.6027
CDK-activating kinase assembly factor MAT1Homo sapiens (human)3.106
Cyclin-dependent kinase 6Homo sapiens (human)0.0168
Cyclin-dependent-like kinase 5 Homo sapiens (human)0.405
Cyclin-dependent kinase 5 activator 1Homo sapiens (human)0.405

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Goldman, JW; Hurt, KC; Koustenis, A; Paz-Ares, L; Reck, M; Shi, P1

Trials

1 trial(s) available for erlotinib hydrochloride and abemaciclib

ArticleYear
Treatment Rationale and Study Design for the JUNIPER Study: A Randomized Phase III Study of Abemaciclib With Best Supportive Care Versus Erlotinib With Best Supportive Care in Patients With Stage IV Non-Small-Cell Lung Cancer With a Detectable KRAS Mutati
    Clinical lung cancer, 2016, Volume: 17, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aminopyridines; Antineoplastic Combined Chemotherapy Protocols; Benzimidazoles; Biomarkers, Tumor; Carcinoma, Non-Small-Cell Lung; Cisplatin; Drug Resistance, Neoplasm; Erlotinib Hydrochloride; Female; Follow-Up Studies; Humans; Lung Neoplasms; Male; Middle Aged; Mutation; Neoplasm Staging; Palliative Care; Prognosis; Proto-Oncogene Proteins p21(ras); Salvage Therapy; Survival Rate; Young Adult

2016