Page last updated: 2024-09-05

erlotinib hydrochloride and 2-methoxyestradiol

erlotinib hydrochloride has been researched along with 2-methoxyestradiol in 2 studies

Compound Research Comparison

Studies
(erlotinib hydrochloride)
Trials
(erlotinib hydrochloride)
Recent Studies (post-2010)
(erlotinib hydrochloride)
Studies
(2-methoxyestradiol)
Trials
(2-methoxyestradiol)
Recent Studies (post-2010) (2-methoxyestradiol)
4,3537863,03377911315

Protein Interaction Comparison

ProteinTaxonomyerlotinib hydrochloride (IC50)2-methoxyestradiol (IC50)
Tubulin alpha-1A chainSus scrofa (pig)2.2
Tubulin beta chainSus scrofa (pig)2.2
Tubulin beta-2B chainBos taurus (cattle)3.48
Similar to alpha-tubulin isoform 1 Bos taurus (cattle)3.0667
Similar to alpha-tubulin isoform 1 Bos taurus (cattle)3.9

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (50.00)24.3611
2020's1 (50.00)2.80

Authors

AuthorsStudies
Heinonen, T; Huttala, O; Mannerström, M; Sabell, E; Sarkanen, JR; Toimela, T; Ylikomi, T1
Chen, Z; Guo, H; Hu, W; Jiao, M; Jin, T; Li, Y; Lu, M; Ni, J; Wang, Z; Wu, H; Yang, Y; Yao, Y; Yuan, A; Zhang, H; Zheng, S1

Other Studies

2 other study(ies) available for erlotinib hydrochloride and 2-methoxyestradiol

ArticleYear
Intra-laboratory validated human cell-based in vitro vasculogenesis/angiogenesis test with serum-free medium.
    Reproductive toxicology (Elmsford, N.Y.), 2017, Volume: 70

    Topics: 2-Methoxyestradiol; Adipose Tissue; Aspirin; Cells, Cultured; Culture Media; Drug-Related Side Effects and Adverse Reactions; Erlotinib Hydrochloride; Estradiol; Human Umbilical Vein Endothelial Cells; Humans; Laboratories; Levamisole; Mannitol; Methimazole; Neovascularization, Physiologic; Reproducibility of Results; Serum; Stromal Cells; Teratogens; Toxicity Tests; Umbilical Cord; Vascular Endothelial Growth Factor A

2017
2-Methoxyestradiol synergizes with Erlotinib to suppress hepatocellular carcinoma by disrupting the PLAGL2-EGFR-HIF-1/2α signaling loop.
    Pharmacological research, 2021, Volume: 169

    Topics: 2-Methoxyestradiol; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Basic Helix-Loop-Helix Transcription Factors; Carcinoma, Hepatocellular; Cell Line, Tumor; DNA-Binding Proteins; Drug Synergism; ErbB Receptors; Erlotinib Hydrochloride; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Liver Neoplasms; Male; Mice, Inbred BALB C; Mice, Inbred NOD; Mice, Nude; Neoplasm Transplantation; RNA-Binding Proteins; Signal Transduction; Transcription Factors

2021