Page last updated: 2024-09-05

erlotinib and vincristine

erlotinib has been researched along with vincristine in 7 studies

Compound Research Comparison

Studies
(erlotinib)
Trials
(erlotinib)
Recent Studies (post-2010)
(erlotinib)
Studies
(vincristine)
Trials
(vincristine)
Recent Studies (post-2010) (vincristine)
22101802460117

Protein Interaction Comparison

ProteinTaxonomyerlotinib (IC50)vincristine (IC50)
Tubulin beta-4A chainHomo sapiens (human)0.5
Tubulin beta chainHomo sapiens (human)0.5
Tubulin alpha-3C chainHomo sapiens (human)0.5
Tubulin alpha-1B chainHomo sapiens (human)0.5
Tubulin alpha-4A chainHomo sapiens (human)0.5
Tubulin beta-4B chainHomo sapiens (human)0.5
Tubulin beta-3 chainHomo sapiens (human)0.5
Tubulin beta-2A chainHomo sapiens (human)0.5
Beta-tubulin Leishmania donovani1
Tubulin beta-8 chainHomo sapiens (human)0.5
Tubulin beta-2B chainBos taurus (cattle)1.8
Tubulin alpha-3E chainHomo sapiens (human)0.5
Tubulin alpha-1A chainHomo sapiens (human)0.5
Similar to alpha-tubulin isoform 1 Bos taurus (cattle)1.8
Similar to alpha-tubulin isoform 1 Bos taurus (cattle)1.8
Tubulin alpha-1C chainHomo sapiens (human)0.5
Tubulin beta-6 chainHomo sapiens (human)0.5
Tubulin beta-2B chainHomo sapiens (human)0.5
Tubulin beta-1 chainHomo sapiens (human)0.5

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (14.29)29.6817
2010's6 (85.71)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
Benfenati, E; Raska, I; Toropov, AA; Toropova, AP1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Abdelazeem, AH; Amjad, MW; Bukhari, SNA; Qin, HL; Raja, MAG; Youssif, BGM; Zha, GF1
Abdelazeem, AH; Abdelgawad, MA; Abdelrahman, MH; Bukhari, SNA; Ibrahim, HM; Mohamed, MFA; Salem, OIA; Treambleau, L; Youssif, BGM1
Abdelatef, SA; Abdelazeem, AH; Abdellatif, KRA; Amin, NH; El-Saadi, MT; Omar, HA1

Reviews

1 review(s) available for erlotinib and vincristine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

6 other study(ies) available for erlotinib and vincristine

ArticleYear
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
QSPR modeling of octanol/water partition coefficient of antineoplastic agents by balance of correlations.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:4

    Topics: Antineoplastic Agents; Models, Chemical; Octanols; Quantitative Structure-Activity Relationship; Water

2010
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
Discovery of potential anticancer multi-targeted ligustrazine based cyclohexanone and oxime analogs overcoming the cancer multidrug resistance.
    European journal of medicinal chemistry, 2017, Jul-28, Volume: 135

    Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cyclohexanones; Dose-Response Relationship, Drug; Drug Discovery; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Humans; Molecular Docking Simulation; Molecular Structure; Oximes; Pyrazines; Structure-Activity Relationship

2017
Design, synthesis, mechanistic and histopathological studies of small-molecules of novel indole-2-carboxamides and pyrazino[1,2-a]indol-1(2H)-ones as potential anticancer agents effecting the reactive oxygen species production.
    European journal of medicinal chemistry, 2018, Feb-25, Volume: 146

    Topics: Animals; Antineoplastic Agents; Antioxidants; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; ErbB Receptors; Humans; Indoles; Male; Mice; Models, Molecular; Molecular Structure; Neoplasms, Experimental; Polymerization; Proto-Oncogene Proteins B-raf; Pyrazines; Reactive Oxygen Species; Small Molecule Libraries; Structure-Activity Relationship; Tubulin

2018
Design, synthesis and anticancer evaluation of novel spirobenzo[h]chromene and spirochromane derivatives with dual EGFR and B-RAF inhibitory activities.
    European journal of medicinal chemistry, 2018, Apr-25, Volume: 150

    Topics: Antineoplastic Agents; Benzopyrans; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; ErbB Receptors; Humans; Molecular Structure; Protein Kinase Inhibitors; Proto-Oncogene Proteins B-raf; Spiro Compounds; Structure-Activity Relationship

2018