Page last updated: 2024-09-05

erlotinib and raltitrexed

erlotinib has been researched along with raltitrexed in 2 studies

Compound Research Comparison

Studies
(erlotinib)
Trials
(erlotinib)
Recent Studies (post-2010)
(erlotinib)
Studies
(raltitrexed)
Trials
(raltitrexed)
Recent Studies (post-2010) (raltitrexed)
2210180580143121

Protein Interaction Comparison

ProteinTaxonomyerlotinib (IC50)raltitrexed (IC50)
Thymidylate synthase Escherichia coli7.0667
Dihydrofolate reductaseHomo sapiens (human)1.8578
Thymidylate synthaseLacticaseibacillus casei8.2667
Thymidylate synthaseHomo sapiens (human)1.208
Thymidylate synthaseMus musculus (house mouse)0.67
Thymidylate synthaseEscherichia coli K-122.32
Dihydrofolate reductaseEscherichia coli K-122.32
Folate receptor betaHomo sapiens (human)0.384
Folate receptor alphaHomo sapiens (human)0.015
Non-receptor tyrosine-protein kinase TYK2Homo sapiens (human)0.26
Reduced folate transporterHomo sapiens (human)0.0063
Thymidylate synthase Rattus norvegicus (Norway rat)0.9
Bifunctional dihydrofolate reductase-thymidylate synthaseToxoplasma gondii1.7956
Proton-coupled folate transporterHomo sapiens (human)0.0995

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Benfenati, E; Raska, I; Toropov, AA; Toropova, AP1
Bailey-Downs, LC; Gangjee, A; Ihnat, MA; Kisliuk, RL; Thorpe, JE; Zhao, Y1

Other Studies

2 other study(ies) available for erlotinib and raltitrexed

ArticleYear
QSPR modeling of octanol/water partition coefficient of antineoplastic agents by balance of correlations.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:4

    Topics: Antineoplastic Agents; Models, Chemical; Octanols; Quantitative Structure-Activity Relationship; Water

2010
Novel tricyclic indeno[2,1-d]pyrimidines with dual antiangiogenic and cytotoxic activities as potent antitumor agents.
    Bioorganic & medicinal chemistry, 2012, Jul-15, Volume: 20, Issue:14

    Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Chick Embryo; Drug Screening Assays, Antitumor; Humans; Indenes; Melanoma, Experimental; Mice; Pyrimidines; Receptor, Platelet-Derived Growth Factor beta

2012