Compounds > erlotinib
Page last updated: 2024-09-05

erlotinib and propafenone

erlotinib has been researched along with propafenone in 5 studies

Compound Research Comparison

Studies
(erlotinib)		Trials
(erlotinib)		Recent Studies (post-2010)
(erlotinib)		Studies
(propafenone)		Trials
(propafenone)		Recent Studies (post-2010) (propafenone)
22101801,471268239

Protein Interaction Comparison

ProteinTaxonomyerlotinib (IC50)propafenone (IC50)
Potassium channel subfamily K member 3Homo sapiens (human)5.1
ATP-binding cassette sub-family C member 9Homo sapiens (human)2.2
5-hydroxytryptamine receptor 4Cavia porcellus (domestic guinea pig)0.384
Potassium channel subfamily K member 2Homo sapiens (human)7.6
Cytochrome P450 1A2Homo sapiens (human)3.292
Beta-2 adrenergic receptorHomo sapiens (human)0.052
Aldo-keto reductase family 1 member B1Rattus norvegicus (Norway rat)3.016
ATP-dependent translocase ABCB1Homo sapiens (human)0.3311
Beta-1 adrenergic receptorHomo sapiens (human)0.354
Cytochrome P450 2D6Homo sapiens (human)4.6034
Beta-3 adrenergic receptorHomo sapiens (human)0.424
5-hydroxytryptamine receptor 1ARattus norvegicus (Norway rat)1.637
Sodium-dependent noradrenaline transporter Homo sapiens (human)3.016
5-hydroxytryptamine receptor 2AHomo sapiens (human)0.654
5-hydroxytryptamine receptor 2CHomo sapiens (human)0.384
5-hydroxytryptamine receptor 1BRattus norvegicus (Norway rat)1.637
5-hydroxytryptamine receptor 2BHomo sapiens (human)0.092
5-hydroxytryptamine receptor 6Homo sapiens (human)1.863
Sodium-dependent dopamine transporter Homo sapiens (human)1.868
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)1.3733
Sodium channel protein type 5 subunit alphaHomo sapiens (human)2.245
ATP-sensitive inward rectifier potassium channel 11Homo sapiens (human)2.2
Sigma non-opioid intracellular receptor 1Homo sapiens (human)2.61

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (20.00)29.6817
2010's4 (80.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Dalvie, D; Loi, CM; Smith, DA1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Chen, EC; Chien, HC; Giacomini, KM; Huang, Y; Khuri, N; Liang, X; Sali, A; Stecula, A; Yee, SW1

Reviews

1 review(s) available for erlotinib and propafenone

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

4 other study(ies) available for erlotinib and propafenone

ArticleYear
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Which metabolites circulate?
    Drug metabolism and disposition: the biological fate of chemicals, 2013, Volume: 41, Issue:5

    Topics: Humans; Metabolic Clearance Rate; Pharmaceutical Preparations

2013
Discovery of Competitive and Noncompetitive Ligands of the Organic Cation Transporter 1 (OCT1; SLC22A1).
    Journal of medicinal chemistry, 2017, 04-13, Volume: 60, Issue:7

    Topics: Drug Discovery; HEK293 Cells; Humans; Ligands; Molecular Docking Simulation; Organic Cation Transporter 1; Small Molecule Libraries

2017