Page last updated: 2024-09-05

erlotinib and profenamine

erlotinib has been researched along with profenamine in 2 studies

Compound Research Comparison

Studies (erlotinib)	Trials (erlotinib)	Recent Studies (post-2010) (erlotinib)	Studies (profenamine)	Trials (profenamine)	Recent Studies (post-2010) (profenamine)
221	0	180	65	0	24

Protein Interaction Comparison

Protein	Taxonomy	profenamine (IC50)
Cholinesterase	Homo sapiens (human)	0.255
Muscarinic acetylcholine receptor M1	Rattus norvegicus (Norway rat)	0.72
Muscarinic acetylcholine receptor M3	Rattus norvegicus (Norway rat)	0.72
Muscarinic acetylcholine receptor M4	Rattus norvegicus (Norway rat)	0.72
Muscarinic acetylcholine receptor M5	Rattus norvegicus (Norway rat)	0.72
Muscarinic acetylcholine receptor M2	Rattus norvegicus (Norway rat)	0.72
Acetylcholinesterase	Homo sapiens (human)	0.27
Cholinesterase	Equus caballus (horse)	0.72

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	2 (100.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ	1
Chen, EC; Chien, HC; Giacomini, KM; Huang, Y; Khuri, N; Liang, X; Sali, A; Stecula, A; Yee, SW	1

Other Studies

2 other study(ies) available for erlotinib and profenamine

Article	Year
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship	2012
Discovery of Competitive and Noncompetitive Ligands of the Organic Cation Transporter 1 (OCT1; SLC22A1). Journal of medicinal chemistry, 2017, 04-13, Volume: 60, Issue:7 Topics: Drug Discovery; HEK293 Cells; Humans; Ligands; Molecular Docking Simulation; Organic Cation Transporter 1; Small Molecule Libraries	2017

Article

Year

Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.

Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012

Discovery of Competitive and Noncompetitive Ligands of the Organic Cation Transporter 1 (OCT1; SLC22A1).

Journal of medicinal chemistry, 2017, 04-13, Volume: 60, Issue:7

Topics: Drug Discovery; HEK293 Cells; Humans; Ligands; Molecular Docking Simulation; Organic Cation Transporter 1; Small Molecule Libraries

2017