Page last updated: 2024-09-05

erlotinib and guanabenz

erlotinib has been researched along with guanabenz in 3 studies

Compound Research Comparison

Studies
(erlotinib)
Trials
(erlotinib)
Recent Studies (post-2010)
(erlotinib)
Studies
(guanabenz)
Trials
(guanabenz)
Recent Studies (post-2010) (guanabenz)
22101804464296

Protein Interaction Comparison

ProteinTaxonomyerlotinib (IC50)guanabenz (IC50)
trace amine-associated receptor 1Homo sapiens (human)1.173
Solute carrier family 22 member 1 Homo sapiens (human)4.85
5-hydroxytryptamine receptor 4Cavia porcellus (domestic guinea pig)0.204
Alpha-2A adrenergic receptorHomo sapiens (human)0.041
Alpha-2B adrenergic receptorHomo sapiens (human)0.149
Alpha-2C adrenergic receptorHomo sapiens (human)1.106
5-hydroxytryptamine receptor 1ARattus norvegicus (Norway rat)2.068
Amine oxidase [flavin-containing] AHomo sapiens (human)1.787
Alpha-1D adrenergic receptorHomo sapiens (human)0.472
5-hydroxytryptamine receptor 2AHomo sapiens (human)0.392
5-hydroxytryptamine receptor 2CHomo sapiens (human)0.204
5-hydroxytryptamine receptor 1BRattus norvegicus (Norway rat)2.068
5-hydroxytryptamine receptor 2BHomo sapiens (human)0.097

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (33.33)29.6817
2010's2 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Chen, EC; Chien, HC; Giacomini, KM; Huang, Y; Khuri, N; Liang, X; Sali, A; Stecula, A; Yee, SW1

Other Studies

3 other study(ies) available for erlotinib and guanabenz

ArticleYear
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
    Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19

    Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship

2009
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Discovery of Competitive and Noncompetitive Ligands of the Organic Cation Transporter 1 (OCT1; SLC22A1).
    Journal of medicinal chemistry, 2017, 04-13, Volume: 60, Issue:7

    Topics: Drug Discovery; HEK293 Cells; Humans; Ligands; Molecular Docking Simulation; Organic Cation Transporter 1; Small Molecule Libraries

2017